Datasheet of Foretinib(GSK1363089)

Detailed information:
http://www.sun-shinechem.com/Details/Foretinib(GSK1363089)/717/849217-64-7.html

USD250.0/50.0mg;
Price USD400.0/100.0mg
Please send your email to sales@sun-shinechem.com for other package.

Product Name Foretinib(GSK1363089)

N-(3-fluoro-4-(6-methoxy-7-(3-morpholinopropoxy)quinolin-4-yloxy)phenyl)-N-
Chemical Name
(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

Synonyms Foretinib,GSK1363089,XL880

CAS No. 849217-64-7 Catalog No 51705

O NH2
Molecular Weight 632.65 O F
O
N O
Molecular Formula C34H34F2N4O6 O

N N O
Other information N/A F

Items Specifications Results

Appearance Off-white solid Complies

HNMR 400MHz,d6-DMSO Complies

Analysis
HPLC 98.0% Complies

Storage condition Kept under dry and cool condition

The above substance has been tested according to In house Standards, and it
Conclusion
meets requirements.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com
 Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR,
mostly for Met and KDR with IC50of 0.4 nM and 0.9 nM. Less potent against Ron,
Description Flt-1/3/4, Kit, PDGFR/ and Tie-2, and little activity to FGFR1 and EGFR.

No.8 Rd, The Great Wall Park, Donghu High-Tech District 430074, Wuhan, China
Tel: 0086-27-59253327||Email:sales@sun-shinechem.com||Web:www.sun-shinechem.com