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October 2016

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Buyers Guidebook

Astaxanthin Acquisition
Researching and choosing the best astaxanthin
ingredients for supplements and functional foods
by Sandy Almendarez

Underwritten by:
Astaxanthin
Buyers Guidebook
Table of Contents
SECTION I
Astaxanthin Acquisition............................................................ 3

SECTION II
Astaxanthin Buyers Guidebook............................................... 9

SECTION III
Astaxanthin Ingredient Listing ............................................. 16
Natural Products INSIDER | Astaxanthin Buyers Guidebook

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Astaxanthin Acquisition
Researching and choosing the best astaxanthin
ingredients for supplements and functional foods
by Sandy Almendarez

Astaxanthin gives salmon and lobster their rich pink and red hues, but most
consumers want the health benefits of the antioxidant-rich carotenoid without sucking
on seafood every day.
Research has shown astaxanthin helps immune,1 brain,2 heart,3 skin,4 sexual5 and
eye6 health. Further studies have demonstrated astaxanthins ability to improve exercise
endurance7 and reduce inflammation.8
Thankfully, astaxanthin can be sourced in less fishy ways. But, it mostly comes from
the waters.
According to the American Botanical Council (ABC), most commercially available
astaxanthin is harvested from algae. Specifically, Haematococcus pluvialis, a freshwater
species of chlorophyta, is often cultivated for its astaxanthin content.
Natural astaxanthin exist in a variety of organisms, such as shrimp shell, crab shell and
red yeast, but the content of astaxanthin in those is very low, and the extraction process
is very complicated, said Carol Cheow, general manager of sales and marketing,
Cactus Botanics, who said her company sources its astaxanthin from H. Pluvialis.
H. pluvialis life cycle comprises two stages: a green, motile, vegetative stage in which
the cells continuously divide and synthesize chlorophyll; and a red, non-motile resting
stage where cell division stops, chlorophyll content remains constant, and astaxanthin
content and cellular dry weight continuously increase, according to a U.S. patent (no.
6022701) issued to Ben-Gurion University of the Negev, Beersheba, Israel, in 2000.
The optimal environmental and nutritional conditions required for these two stages
Natural Products INSIDER | Astaxanthin Buyers Guidebook

are quite different, the patent authors noted. For vegetative growth, full nutrient
medium, moderate light intensity, and adequate temperature and pH are essential.
For the resting stage, however, no nutrient (except carbon) is required and higher light
intensity (e.g., sunlight) is necessary for faster astaxanthin accumulation. Due to such
discrepancies, the two stages must be separated into different cultivating systems with
different media accordingly.
Astaxanthin suppliers that work with naturalrather than syntheticastaxanthin
produce the initial phase of H. pluvialis in closed cultured systems, and then transfer the
microalgae to an open pond or photobioreactors.
Cyanotech Corp., which has been commercially producing microalgal products for
more than 21 years, harvests H. pluvialis on the Kona Coast of the Big Island of Hawaii
PAGE
to create its BioAstin astaxanthin. The initial production of H. pluvialis takes place in
3 closed culture systems, according to Cyanotechs website, followed by a five- to
seven-day reddening cycle conducted in 500,000-liter open culture ponds. After the
reddening cycle, the cultures are harvested, washed and dried. Then, the company
uses supercritical carbon dioxide (CO2) to extract the astaxanthin in an oleoresin form.
In contrast, the second stage of BGGs astaxanthin (AstaZine) is cultivated in a
closed photobioreactor system in the Yunnan Province in southern China. BGGs
website said this design avoids microbial contamination and enhances control of the
culture conditions and process.
Cyanotch countered that closed culture production of microalgal products dont
eliminate contamination. Closed culture systems can and are contaminated by
unwanted algae, fungi and protozoa, according to the Cyanotech website. When this
does occur, elimination of the biological contamination in closed culture systems can be
very difficult because of the high surface area and many nooks and crannies in such
systems. The company further noted that its
closed culture systems and open pond systems Every small change of the
have been designed to minimize contamination. environment, such as light,
As shown in a SupplySide documentary, BGGs
temperature and PH, will make
process starts with H. pluvialis being grown in a
sterilized beaker filled with a growth medium, which [the microalgae] unhappy.
stays in an incubation room for one week. The Eric Pan, director and chief
mixture is then transferred to outdoor technology officer, Ginkgo Asta, BGG
phtotobioreactor panels, where the algae receive
food and sunlight for additional incubation. Then, the mixture goes into a glass tube
system, which is housed outside, so sunlight can affect the process.
Every small change of the environment, such as light, temperature and PH, will make
[the microalgae] unhappy, said Eric Pan, director and chief technology officer, Ginkgo
Asta, BGG, in the documentary. The bloom of contamination like bacteria, mircoalge
and fungi will change their growth environment.
BGG allows the H. pluvialis to grow for one to two weeks in the glass tubes to allow it
Natural Products INSIDER | Astaxanthin Buyers Guidebook

to reach its target concentration. To ensure temperatures dont get too high, BGG uses
a drip system of flowing water to cool the glass tubes where the algae is grown. BGG
uses enclosed photobioreactors and natural sunshine, as compared to other producers
who use open ponds susceptible to contamination, or indoor systems which use
artificial light, said Joe Huff, vice president of sales, BGG North America. BGGs algae
cultivation is located in a temperate climate with plentiful sunshine year round.
Algatechnologies manufactures natural astaxanthin using closed cultivation systems
exposed to natural sunlight. Then, Algatechnologies astaxanthin is extracted using
super-critical CO2 technology, obtaining 10-percent astaxanthin in oleoresin form, with
no solvent extractions, according to the company.
Likewise, Joe Kuncewitch, national sales manager, AstaReal USA (a Fuji Chemical
PAGE
Industry Group company), noted AstaREAL commercially cultivates its H. pluvialis algae
4 using bioreactors and fresh water microalgae. AstaReal is cultivated in Washington
state, which complements its facility near Stockholm, Sweden. Our Astaxanthin is
extracted in the United States, so even though we are a subsidiary of a Japanese
pharmaceutical company, our natural astaxanthin oil is 100-percent made in America.
H. pluvialis likes to grow in temperate climate, so China has become an ideal place for
cultivation, according to Cheow, who said Cactus Botanics algae growth base is in
southwest China.

Watch how BGG produces astaxanthin


in the SupplySide Global Experience
Documentary: Modernizing the Chinese
Supply Chain.
Steve Myers, INSIDER managing editor, and
Jon Benninger, Informa Health & Nutrition vice
president, look inside operations at a botanical
extract production facility and algae cultivation
plant as examples of how Chinese suppliers are
modernizing the supply chain through
investments in quality, sustainability, research and
product development. The documentary shows
BGGs newest facility, a microalgae cultivation plant in Southwest China
currently focused on producing natural astaxanthin from
Haematococcus pluvialis. Located in Shilin, outside of Kunming City in
Chinas Yunnan Province, the facility takes advantage of clean natural
resources and sunshine to help drive its closed photobioreactor system
for cultivating astaxanthin-rich microalgae in a controlled and sustainable
manner. The 100-plus-acre facility also includes laboratories for testing
Natural Products INSIDER | Astaxanthin Buyers Guidebook

and research and development (R&D).

4:28 / 12:13

Renewable Resource
While many natural resources need to contend with harvesting and environmental
concerns, Sustainability is one of the best features of astaxanthin (H. pluvialis
production), said Gen Lipkovicius, international marketing manager, PIVEG Inc. It is
produced rather than harvested from wild species.
This way, companies have a secure knowledge of how much they can produce and
moderate the effects of Mother Nature.
PAGE Huff agreed, noting BGGs natural astaxanthin is sustainable because its cultivated
5 from algae in photobioreactors, which is a controlled environment.
Correct Testing
To ensure products are contaminate-free, astaxanthin, like any ingredients designed
for use in supplements or functional foods, needs to be tested for purity and identity.
Cheow said the two methods to test astaxanthin are UV (ultraviolet) and HPLC
(high-performance liquid chromatography), noting Cactus Botanics uses HPTLC
(high-performance thin layer chromatography) to test its astaxanthin.
Potency and purity are key factors because its necessary to be sure of what
you are consuming, or, as a contract manufacturer, what you are going to put into
your final product, Kuncewitch said, noting that Fuji developed the astaxanthin assay
that was adopted by the U.S. Pharmacopeia (USP)/FCC in their 2013 chemical codex.
There is an HPLC test available to all legitimate seekers that can readily identify the
source, potency and purity of their
astaxanthin product. The power of astaxanthin as an
However, Kuncewitch said some
antioxidant can be a pitfall in
companies test for astaxanthin using UV
testing for carotenoids. This method is formulation. Stability can be an
inaccurate, misleading and allows fringe issue as oxygen can react with the
suppliers to pass the sniff test without nutrient, causing it to lose potency.
much effort or vetting, he said.

Formulation and Delivery


The power of astaxanthin as an antioxidant can be a pitfall in formulation.
Stability can be an issue as oxygen can react with the nutrient, causing it to lose
potency. To overcome this, Huff suggested brands purchase a stable oleoresin
or a microencapsulated beadlet.
To formulate asxtanthin into liquids, Cheow reminded that brands will need to use a
form that is water soluble.

Delivery Forms for Astaxanthin


Natural Products INSIDER | Astaxanthin Buyers Guidebook

Ingredient Form Delivery System


Powders (uncracked and cracked) Hard capsule and tablet*
Soft capsule, dairy, juice, beverages, candy, baked,
Extracts (powder or oil)
beauty products and high-quality capsules*
10-percent oleoresin oil Softgels and two-piece liquid capsules**

Two-piece capsules, beverage powder pre-mixes and


2-percent extract powder
tablet applications**
Specialty hard capsules and liquid blends,
1.5-percent water soluble liquids
such as RTD (ready-to-drink) beverages**
PAGE
6 Source: *Carol Cheow, general manager of sales and marketing, Cactus Botanics, and
**Joe Kuncewitch, national sales manager, AstaReal USA
Natural product companies looking to source astaxanthin for their
supplements, or functional foods and beverages need to consider cultivation
methods, delivery forms and supplier traits before entering into a partnership.
And as Kuncewitch reminded, Know your source and trust your source.
Dont purchase on price alone.

Questions to Ask an Astaxanthin Supplier


Before Signing a Contract
Joe Kuncewitch, national sales manager, AstaReal USA, said brand owners
should ask all of these questions before discussing price:
What country is it produced in?
What is the source of the astaxanthin: natural or synthetic? If its natural from
Haematococcus pluvialis, how is the algae cultivated?
What type of extraction processed is employed? Is the astaxanthin extracted using
a CO2 method or are co-solvents also being introduced? Are there any residual
solvents such as ethanol, methanol, isopropanol, acetone or hexane?
Gen Lipkovicius, international marketing manager, PIVEG Inc., said these
factors are important to consider when selecting an Astaxanthin supplier:
Does the product test properly, and is it stable?
Does the supplier hold up-to-date, internationally recognized and audited
certifications that ensure the product is produced under proper conditions?
Does the product and the supplier comply with the regulatory requirements of the
target market?
Does the manufacturer guarantee all results that are listed on the specification?
What country will the product be shipping from? (This affects import taxes.)
What is the lead time to receive products?
Natural Products INSIDER | Astaxanthin Buyers Guidebook

PAGE
7
U.S. Astaxanthin Regulations
In April 2009, FDA approved astaxanthin as a color additive for fish feed,
and in 2000, FDA approved H. pluvialis algae meal and Phaffia yeast for
use in fish feed. For human supplementation in the United States, some
ingredients have obtained GRAS (generally recognized as safe) status
or have been submitted to FDA under new dietary ingredient notification
(NDIN) regulations, allowing them to be used as dietary ingredients.
In winter 2011, both Algatechnologies AstaPure astaxanthin brand
and Cyanotechs BioAstin earned GRAS status, allowing the ingredients
to be used in foods, beverages and supplements in the United States.
In September 2011, Cyanotech followed its GRAS status by announcing
it received a letter of no objection from FDA regarding its NDIN for a
12-mg/d dose of BioAstin, which further paved its acceptable use in
U.S. supplements. And in February 2013, Fuji Health Science Inc. also
reported a successful NDIN for its AstaREAL astaxanthin at 12 mg/d.

References
1. Nakagawa K et al. Antioxidant effect of astaxanthin on phospholipid peroxidation in human
erythrocytes. Br J Nutr. 2011 Jun;105(11):1563-71. DOI: 10.1017/S0007114510005398.
2. Liu X. and Osawa T. (2009) Astaxanthin Protects Neuronal Cells against Oxidative Damage
and is a Potent Candidate for Brain Food. Forum Nutr. Basel, Karger, 2009, vol 61, pp 129-
135. DOI: 10.1159/000212745.
3. Fassett RG and Coombes JS. Astaxanthin: a potential therapeutic agent in cardiovascular
disease. Mar Drugs. 2011 Mar 21;9(3):447-65. DOI: 10.3390/md9030447.
Natural Products INSIDER | Astaxanthin Buyers Guidebook

4. Suganuma K et al. Astaxanthin attenuates the UVA-induced up-regulation of matrix-


metalloproteinase-1 and skin fibroblast elastase in human dermal fibroblasts. J Dermatol
Sci 2010;58(2):136-142. DOI: 10.1016/j.dermsci.2010.02.009.
5. Comhaire FH et al. Combined conventional/antioxidant Astaxanthin treatment for male
infertility: a double blind, randomized trial. Asian J Androl 2005;7:257-62.
6. Fassett RG et al. Astaxanthin vs placebo on arterial stiffness, oxidative stress and
inflammation in renal transplant patients (Xanthin): a randomised controlled trial. BMC.
Nephrol. 2008;9:17. DOI: 10.1186/1471-2369-9-17.
7. Ikeuchi M et al. Effects of astaxanthin supplementation on exercise-induced fatigue in
mice. Biol Pharm Bull. 2006 Oct;29(10):2106-10.
8. Speranza L et al. Astaxanthin treatment reduced oxidative induced pro-inflammatory
cytokines secretion in U937: SHP-1 as a novel biological target. Mar Drugs. 2012
PAGE Apr;10(4):890-9. DOI: 10.3390/md10040890.
8
Astaxanthin Buyers Guidebook 2016
A Clover Nutrition Inc. Anhui Viley Intl. Co. Ltd.
Green Harbor #1 Rm. 1612, Huifend Bldg.
Hi-tech Zone No. 665 Huangshan Road
Xian, Shaanxi Sheng China 710000 Hefei, Anhui Sheng China 230031
Phone: +00-86-150-94057355 Phone: +05-51-62817786
SalesEmail: info@clovercn.com SalesEmail: maxiaowei28@163.com
www.clovercn.com
Aqua Health Labs
A&A Pharmachem Inc. 2011 W. Belmont
4-77 Auriga Drive Chicago, IL United States 60618
Ottawa, ON Canada K2E 7Z7 Phone: (630)803-7701
Phone: (613)228-2600 SalesEmail: jmarkuso@aquahealthlabs.com
SalesEmail: naveen@aapharmachem.com www.aquahealthlabs.com
www.aapharmachem.com
Arista Industries Inc.
ACB SciTech Inc. 557 Danbury Road
1528 Bluff Court Wilton, United States 06897
Diamond Bar, CA United States 91765 Phone: (203)761-1009
Phone: (626)380-9319 SalesEmail: info@aristaindustries.com
SalesEmail: bruce@acbscitech.com www.aristaindustries.com
www.acbscitech.com
AstaReal Inc./Fuji Health Science
Aker BioMarine Antarctic US 3 Terri Lane
410 Newport Way N.W., Ste. D Ste. 12
Issaquah, WA United States 98027 Burlington, NJ United States 08016
Phone: (206)855-6736 Phone: (609)386-3030
SalesEmail: Molly.McMahon@akerbiomarine.com SalesEmail: joek@fujihealthscience.com
www.superbakrill.com www.astarealusa.com

Algatechnologies Aurobindo Pharma Ltd.


Kibbutz ketura Nutraceuticals Division - The Water Mark Bldg.,
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D.N Hevel Eilot, Central District Israel 8884000 Plot #11


Phone: +97-25-468-94394 Survey #9, Kondapur Hi-Tech City
www.algatech.com Hyderabad, Telangana State, Andhra Pradesh
India 500084
Amazon Forest Inc. Phone: +91-40-667-25361
102-116 Hillcrest Ave. SalesEmail: cnbhagawan@aurobindo.com
Ledgewood, NJ United States 07852 www.aurobindo.com
Phone: (973)584-3900
www.amazonforest.net Aviva Naturals Corp.
10A Jules Lane
Ambe Phytoextracts Pvt. Ltd. New Brunswick, NJ United States 08901
48 Hasanpur, IP Extension Phone: (609) 678-0077
PAGE
Patparganj SalesEmail: sales@avivanaturals.com
9 Delhi, NCT India 110092 www.avivanaturals.com
Phone: +91-11-437-64376
www.ambe-group.com
Astaxanthin Buyers Guidebook 2016
Barrington Nutritionals Changsha Huir Biological-tech Co. Ltd.
500 Mamaroneck Avenue Fl 20 Jindan Bldg.,
Harrison, NY United States 10528 Longping High-tech Park, Furong
Phone: (914)381-3500 Changsha, Hunan China 410126
SalesEmail: sales@barringtonnutritionals.com Phone: +86-731-85785038
www.barringtonnutritionals.com SalesEmail: huixin06@extract-plant.com
www.phyhuir.com
BGG
18301 Von Karman Ave., Ste. 570 Changsha Sunfull Bio-tech Co. Ltd
Irvine, CA United States 92612 18F, Jindan Bldg. A, Longping High-tech Park
Phone: (949)748-7348 Changsha, Hunan China 410126
SalesEmail: joe@bggworld.com Phone: +86-73-182-970067
www.bggworld.com SalesEmail: jan@sunfullbio.com
www.sunfullbio.com
Bio Actives Japan
2-15-9-9F, Kita-Otsuka, Toshima-Ku Chenguang Biotech Group Co. Ltd.
Tokyo, Tokyo Japan 1700004 No. 1 Chenguang Road
Phone: +81-35-981-0601 Quzhou, Hebei China 057250
SalesEmail: taka@bioactivesjapan.com Phone: +86-31-088-50990
www.bioactives.co.jp/ www.hdchenguang.com

Biodroga China Jiangsu Intl. Economic


301 Joseph Carrier & Technical Cooperation Group Ltd.
Vaudreuil-Dorion, QC Canada J7V 5V5 9F., No. 1 Hanzhongmen St.
Phone: (450)510-5599 Nanjing, Jiangsu Sheng China 210029
SalesEmail: biodroga@biodroga.ca Phone: +86-25-865-69853
www.biodroga.ca www.cnjsgroup.com

Blue California CIDIC Co. Ltd.


30111 Tomas 15 Fl., Hodo International Plaza,
Rancho Santa Margarita, 531 Zhongshan Road
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CA United States 92688 Wuxi, Jiangsu Sheng China 214002


Phone: (949)635-1990 Phone: +86-51-082-303030
www.bluecal-ingredients.com SalesEmail: dilinyun@cidic.com.cn
www.cidic.com.cn
Cactus Botanics
1108 W. Valley Blvd., Ste. 6278 Compound Solutions Inc.
Alhambra, CA United States 91803 1930 Palomar Point Way
Phone: (562)340-7402 Ste. 105
SalesEmail: carol.c@cactusbotanics.com Carlsbad, CA United States 92008
www.cactusbotanics.com Phone: (760)739-9881
SalesEmail: mtitlow@compoundsolutions.com
www.compoundsolutions.com
PAGE
10
Astaxanthin Buyers Guidebook 2016
Cyanotech Corporation Hunan Nutramax Inc.
73-4460 Queen Kaahumanu Highway 25/F, Jiahege Bldg.
#102 No. 217 Wanjiali Road
Kailua Kona, HI United States 96740 Changsha, Hunan China 410016
Phone: 808.3314101 Phone: +86-73-182-939656
SalesEmail: aprehn@nutrex-hawaii.com SalesEmail: sales@nutra-max.com
www.nutra-max.com
Divis Laboratories (USA) Inc.
325 Columbia Turnpike, Ste. 305 Hunan Zhengdi Biological Resources
Florham Park, NJ United States 07932 Development Co. Ltd.
Phone: (973)993-1060 Rm. 605, Bldg. A7,
SalesEmail: r.lockhart@divislabs.com Lugu International Industrial Park
www.divisnutraceuticals.com Changsha, Hunan China 410205
Phone: +07-31-85461025
Empirical Labs SalesEmail: export@hnzhengdi.com
1501 Academy Court, #5 www.hnzhengdi.com
Fort Collins, CO United States 80524
Phone: (970)232-3951 Icelandirect Inc.
SalesEmail: info@empirical-labs.com 700 Plaza Drive, 2nd Fl.
www.empirical-labs.com Secaucus, NJ United States 07094
Phone: (800)763-4690 x2
Ennature Biopharma - div. SalesEmail: henry@icelandirect.com
of India Glycols Ltd. www.icelandirect.com
Plot No. 2B, Sector-126, Express Hwy.
Noida, Uttar Pradesh India 201304 Indo World Trading Corp.
Phone: +91-12-030-90263 B-II/6, Mohan Co-op, IndL Est.
www.indiaglycols.com New Delhi, India 110044
Phone: +91-11-467-59700
Fenchem Inc. SalesEmail: indoworld@vsnl.com
15308 El Prado Road www.indo-world.com
Building 8
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Chino, CA United States 91710 INNOBIO Limited


Phone: (909)597-8880 No. 49, DDA
SalesEmail: sales@fenchem.com Dalian, Liaoning China 116600
www.fenchem.com Phone: +86-41-187-406567
www.innobio.cn
Hongjiu Biotech Co. Ltd.
Rm. 2413, No. 572 Zhongshan Road Innophos Nutrition
Dalian, Liaoning China 116023 680 North 700 West
Phone: +86-41-139-682391 North Salt Lake, UT United States 84054
SalesEmail: candy@hongjiu.cn Phone: (801)299-1661
www.hongjiu.cn SalesEmail: monica.mitchell@innophos.com
www.innophosnutrition.com
PAGE
Hunan Jiudian Pharmaceutical Co. Ltd.
11 Hunan Liuyang Bio-pharmaceutical Park
Changsha, Hunan China 410331
Phone: +86-0731-82805547
www.jiudianph.com
Astaxanthin Buyers Guidebook 2016
Jianhe Biotech Co. Ltd. MTC Industries Inc.
Nanhuoying Developing Zone 255 Oser Ave.
Xingtang County Hauppauge, NY United States 11788
Shijaizhuang, Hubei China 315800 Phone: (631)274-4818
Phone: +86-31-183-506700 SalesEmail: tim@mtcindustries.com
SalesEmail: henry.zhao@jh-biotech.com www.mtcindustries.com
www.jh-biotech.com
N&R Industries Inc
Kailu Ever Brilliance Biotechnology Co. Ltd. Rm. 2107, Block A, Epin Meidao Bldg.
1-919, Bldg. 8, E. Block Gaoxin Road, Hi-Tech Zone
Donghuashi Nanli Dongcheng District Xian, Shaanxi Sheng China 710075
Beijing, Beijing China 100062 Phone: +86-29-887-64861
Phone: +86-10-871-03711 SalesEmail: info@nutraii.com
SalesEmail: info@kebiotech.com www.nutraii.com
www.kebiotech.com
Nanjing Health Herb Bio-Tech Co. Ltd.
L.V. Lomas 17 Beijing Road W.
11850 SW 67th Ave. Nanjing, Jiangsu Sheng China 210024
Ste. 110 Phone: +86-25-866-38485
Portland, OR United States 97223 SalesEmail: tzhendong@healthherb.cn
Phone: (800)668-1221 www.healthherb.cn
www.lvlomas.com
Nantong Qihai Nutraceuticals Co. Ltd.
Laurus Labs Pvt. Ltd. 5th Fl., Bldg. 17
2nd Fl., Serene Chambers Zhongnanshijicheng
Road No. 7, Banjara Hills Nantong, Jiangsu Sheng China 226000
Hyderabad, Andhra Pradesh India 500034 Phone: +86-51-355-019226
Phone: +91-40-398-04333 SalesEmail: sales@qhnutraceuticals.com
www.lauruslabs.com www.qhnutraceuticals.com

Liaoning Pharmaceutical Naturalin Bio-Resources Co. Ltd.


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Foreign Trade Corp. B1-402, Lu-Valley Enterprise Square


No. 146 Northeast Great Road No. 27 Wenxuan Road, Lu-Valley
Dadong District Changsha, Hunan China 410205
Shenyang, Liaoning China 110044 Phone: +86-731-84430651
Phone: +86-24-31996036 SalesEmail: thomas@naturalin.com
SalesEmail: lpftc@vip.163.com www.naturalin.com
www.liaoningpharm.com
Neptune Technologies & Bioressources
Maxsun Industries Inc. 545 Promenade Du Centropolis
1967 W. Holt Ave. Ste. 100
Pomona, CA United States 91768 Laval, QC Canada H7T 0A3
Phone: (909)865-1999 Phone: (450)687-2262
PAGE www.maxsunindustries.com SalesEmail: j.khayat@neptunebiotech.com
12 www.neptunebiotech.com
Astaxanthin Buyers Guidebook 2016
Nutracode Purestar Chem Enterprise Co. Ltd.
9 W. 31st St., 25H No. 235 Huangchengdong Road
New York, NY United States 10001 Huzhou, Zhejiang Sheng China 313000
Phone: (610)390-2247 Phone: +86-57-221-57374
SalesEmail: shaun@nutracode.co SalesEmail: sales@purestarchem.com
www.nutracode.co www.purestarchem.com

Nutraland USA Inc. Qingdao Qingmei Biotech Co. Ltd.


212 Technology Drive Rm203A, Hongkong Middle Rd.
Ste. X Qingdao, Shandong Sheng China 266071
Irvine, CA United States 92618 Phone: +86-532-83876123
Phone: (949) 988-7615 SalesEmail: dennis@qingmeibio.com
SalesEmail: xu.sanying@nutralandusa.com www.qingmeibio.com
www.nutralandusa.com
Rimfrost USA LLC
Nutritech Holdings P.O. Box 143
No. 18 Qinling Road Merry Hill, NC United States 27957
Qingdao, Shandong Sheng China 266071 Phone: (252)482-1316
Phone: +86-53-283-868912 SalesEmail: shannon.perry@rimfrostusa.com
SalesEmail: michaelxy@ymail.com www.rimfrostusa.com
www.nutritechcorp.com
Rosun Natural Products Pvt. Ltd.
Olive Lifesciences Pvt. Ltd. 06/2302, Thiruvalluvar Ave.
No 30, Pride Quadra, 4th Fl. No: 1 Tollgate
Bellary Main Road, Hebbal Trichy, Tamil Nadu India 621 216
Bangalore, Karnataka India 560024 Phone: +91-95-000-02396
Phone: +91-80-235-30235 www.rosunnaturalproducts.com
www.olivelifesciences.com
Shaanxi Kingsci Biotechnology Co. Ltd.
Pharmax NA Inc. A-1404 Lijun Our Times,
1300 Valley Vista Drive, Ste. 205B No. 6 Fengcheng 1st Road
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Diamond Bar, CA United States 91765 Xian, Shanghai Shi China 710016
Phone: (909)396 6700 Phone: +86-29-861-81961
www.pharmaxus.com SalesEmail: sales2@kingsci.com
www.kingsci.com
PIVEG Inc.
10455 Sorrento Valley Road Shandong Lanao Biotech Co. Ltd.
Ste. 101 Jinan New Material Industrial Park
San Diego, CA United States 92121 -, Shandong Sheng China 250000
Phone: (858)436-3070 Phone: +86-531-62331337
SalesEmail: roberto.espinoza@piveg.com SalesEmail: service-lanao@hotmail.com
www.piveg.com www.lanao-china.com

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Astaxanthin Buyers Guidebook 2016
Shanghai Freemen Americas LLC Taiyo Intl. Inc.
377 Hoes Lane 5960 Golden Hills Drive
Ste. 240 Minneapolis, MN United States 55416
Piscataway, NJ United States 08854 Phone: (763)398-3003
Phone: (732)981-1288 SalesEmail: billd@taiyoint.com
SalesEmail: li.haisong@freemen.sh.cn www.taiyointernational.com
www.shanghaifreemen.com
TOYOND USA
Shanghai Seebio Biotech Inc. 2885 Sanford Ave. S.W., Ste. 27660
Office No. 502, Building 11, Grandville, Zhejiang Sheng China 49418
Lane 299, Bisheng Road, Phone: +86-18-657-179188
Zhangjiang High-Tech Park,Pudong SalesEmail: sales@toyond.com
Shanghai, Shanghai Shi China 201204 P.R www.toyond.com
Phone: +86-21-50272981 ext.6515
SalesEmail: foodadd@seebio.cn Trafa Pharmaceutical Supplies Inc
www.seebio.cn 138-14273 Knox Way
Richmond, BC Canada V6V 2Z4
Siddharth Intl. Phone: (604)562-4449
Green House, 2nd Fl. Green St. SalesEmail: sales@trafapharmasupplies.com
Mumbai, Maharashtra India 400023 www.trafapharmasupplies.com
Phone: +91-22-226-63119
SalesEmail: vishal@siddhint.com Valensa Intl.
www.siddhint.com 2751 Nutra Lane
Eustis, FL United States 32726
Sino Bio-Tech Co. Ltd. Phone: (352)357-2004
601 Century Pkwy., Ste. 300 SalesEmail: uma@valensa.com
Allen, TX United States 75013 www.valensa.com
Phone: (469)361-3361
SalesEmail: info@nutralifeusa.com Viatal a ZMC Company
www.nutralifeusa.com 2160 N. Central Road
Ste. 111
Natural Products INSIDER | Astaxanthin Buyers Guidebook

Soft Gel Technologies Inc. Fort Lee, NJ United States 07024


6982 Bandini Blvd. Phone: (201)363-8886
Los Angeles, CA United States 90040 SalesEmail: sales@viatalcorp.com
Phone: (323)726-0700 www.viatalcorp.com
SalesEmail: sales@soft-gel.com
www.soft-gel.com Watson Industries Inc.
106 Exchange Place
Sunrise Chemical Co. Ltd. Pomona, CA United States 91768
11 Renmin E. Road Phone: (909)718-0866
Huachang Oriental Plaza, Ste. 1707 SalesEmail: sales@watsonii.com
Zhangjiagang, Jiangsu Sheng China 215600 www.watsonii.com
Phone: +86-51-258-152556
PAGE SalesEmail: SALES@SUNRISE-CHEMICAL.COM
14 www.sunrise-chemical.com
Astaxanthin Buyers Guidebook 2016
Wuhan Healthdream Biological Yongzhou Huamao
Technology Co. Ltd Biotechnology Co. LTD
No.336 of Moshuihu RdWuhan City 2911 Xinglong International Plaza, Hinghua
430051,Hubei,China Economic Development Z
Wuhan, China 430000 Shangrenli Industrial Zone, Shuangpai
Phone: 86-27-84618766 County, Yongzhou City
SalesEmail: info@healthdreambio.com Changsha, Hunan China 410100
www.healthdreambio.com Phone: +00-86-731-82020210
www.hm-herb.com
Xian Healthful Biotechnology Co. Ltd.
A-804 HuiHang Plaza, HangTuo Road Yunnan Alcom Biotech Co. Ltd.
Xian, Shaanxi Sheng China 710001 Ziwu, Chuxiong, Yunnan, P.R.C
Phone: +86-29-626-51717 Yunnan, China 675012
SalesEmail: sales@healthfulbio.com Phone: +86-878-6168627
www.healthfulbio.com SalesEmail: andrew.cheng@alphy.com.cn
www.alphy.com
Xian Tonking Biotech Co. Ltd.
Pioneering R&D Park, No. 69 Jinye Road Yunnan Alphy Biotech Co. Ltd.
Xian High Tech Zone Ziwu Town
Xian, Shaanxi Sheng China 710077 Chuxiong City, Yunnan China 675012
Phone: +86-02-989-388356 Phone: +86-87-861-68627
SalesEmail: cathie@sxherb.com SalesEmail: lihongyan@alphy.com.cn
www.sxherb.com www.alphy.net.cn

Yichang Yonggim Co. Ltd. ZD Pharma LLC


Bldg. 18 Wenshayayuan/Jiangshanfenghua 1909 S Campus Ave.
No. 198 Yanjiang Road Ontario, CA United States 91761
Yichang, Hubei China 443003 Phone: (857)999-5888
Phone: +86-71-763-07507 SalesEmail: zhongdaus@gmail.com
SalesEmail: cjw99999@hotmail.com www.zdpharma.com
www.pharma-chemical.com
Natural Products INSIDER | Astaxanthin Buyers Guidebook

Zhejiang Medicine Co.


Yigeda Bio-Technology Co. Ltd. /Xinchang Pharmaceuticals
B-605 The Gate Tower 98 E. Xinchang Dadao Road
No. 19 ZhongGuanCun St. Xinchang
Beijing, Beijing China 100080 Zhejiang, Zhejiang Sheng China 312500
Phone: +86-10-82486516 Phone: +86-57-586-126668
www.dh-nutrition.com/en SalesEmail: sales@zmc-usa.com
www.xcpharma.com
Yokohama Oils & Fats Industry
1-1 Minamisengencho
Yokohama, Kanagawa, Japan 220-0074
Phone: +81-45-313-8251
PAGE SalesEmail: kan.sadamoto@yof-linda.co.jp
15 www.yof-ec.com
Astaxanthin Ingredient Listing
Astaxanthin Innophos Nutrition Xian Healthful Biotechnology Co. Ltd.
A Clover Nutrition Inc. Jianhe Biotech Co. Ltd. Xian Tonking Biotech Co. Ltd.
A&A Pharmachem Inc. Kailu Ever Brilliance Biotechnology Co. Ltd. Yichang Yonggim Co. Ltd.
ACB SciTech Inc. L.V. Lomas Yigeda Bio-Technology Co. Ltd.
Aker BioMarine Antarctic US Laurus Labs Pvt. Ltd. Yokohama Oils & Fats Industry
Algatechnologies Liaoning Pharmaceutical Foreign Yongzhou Huamao Biotechnology Co. LTD
Amazon Forest Inc. Trade Corp. Yunnan Alcom Biotech Co. Ltd.
Ambe Phytoextracts Pvt. Ltd. Maxsun Industries Inc. Yunnan Alphy Biotech Co. Ltd.
Anhui Viley Intl. Co. Ltd. MTC Industries Inc. ZD Pharma LLC
Aqua Health Labs N&R Industries Inc Zhejiang Medicine Co.
Arista Industries Inc. Nanjing Health Herb Bio-Tech Co. Ltd. /Xinchang Pharmaceuticals
AstaReal Inc./Fuji Health Science Nantong Qihai Nutraceuticals Co. Ltd.
Aurobindo Pharma Ltd. Naturalin Bio-Resources Co. Ltd.
Aviva Naturals Corp. Neptune Technologies & Bioressources
Barrington Nutritionals Nutracode
BGG Nutraland USA Inc.
Bio Actives Japan Nutritech Holdings
Blue California Olive Lifesciences Pvt. Ltd.
Cactus Botanics Pharmax NA Inc.
Changsha Huir Biological-tech Co. Ltd. PIVEG Inc.
Changsha Sunfull Bio-tech Co. Ltd Purestar Chem Enterprise Co. Ltd.
Chenguang Biotech Group Co. Ltd. Qingdao Qingmei Biotech Co. Ltd.
China Jiangsu Intl. Economic & Technical Rimfrost USA LLC
Cooperation Group Ltd. Rosun Natural Products Pvt. Ltd.
CIDIC Co. Ltd. Shaanxi Kingsci Biotechnology Co. Ltd.
Compound Solutions Inc. Shandong Lanao Biotech Co. Ltd.
Cyanotech Corporation Shanghai Freemen Americas LLC
Divis Laboratories (USA) Inc. Shanghai Seebio Biotech Inc.
Empirical Labs Siddharth Intl.
Natural Products INSIDER | Astaxanthin Buyers Guidebook

Ennature Biopharma - div. of India Sino Bio-Tech Co. Ltd.


Glycols Ltd. Soft Gel Technologies Inc.
Fenchem Inc. Sunrise Chemical Co. Ltd.
Hongjiu Biotech Co. Ltd. Taiyo Intl. Inc.
Hunan Jiudian Pharmaceutical Co. Ltd. TOYOND USA
Hunan Nutramax Inc. Trafa Pharmaceutical Supplies Inc
Hunan Zhengdi Biological Valensa Intl.
Resources Development Co. Ltd.
Viatal a ZMC Company
Icelandirect Inc.
Watson Industries Inc.
Indo World Trading Corp.
Wuhan Healthdream Biological
INNOBIO Limited Technology Co. Ltd

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