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Tarleton University
First thing that concerns me for an anesthetic case is the high liver values of the
ALK and GTP- 300 over the high end of normal. Although this could be from the
constant use of prednisone, it should still be taken into consideration when selecting
anesthetic drugs and patient monitoring. This case study doesn’t explain why the dog is
on this constant use of prednisone. Why is Bally on the steroid? Is it allergies? Skin
issues? Why the low platelets? I feel like that should be in something that should be
The effect of surgical drugs can have a more prolonged effect because the liver
may have a harder time metabolizing those drugs. Valium should have been used in
caution in patients with liver disease; same with ketamine because it prolongs the effects
(Plumb, 2011). Those two drugs plus the inhalant anesthesia might have caused the initial
deep plane of anesthesia. Propofol would have been a better induction agent. “Its rapid
also eliminated from the body by extrahepatic mechanisms, as clearance of the drug from
The technician should have taken all of that into account when administering and
monitoring the effects of the induction agents prior to starting inhalant anesthetics. The
clinic I work at, we slowly give the induction agents and given to affect- and its
sometimes not the whole dose. If we notice that their pre-medication and induction agents
References
DACVAA, A. W. (2011, October 01). General anesthesia for patients with renal or
http://veterinarycalendar.dvm360.com/general-anesthesia-patients-with-renal-or-
hepatic-disease-proceedings
Ivancic DVM Todd Deppe DVM DACVIM (internal medicine), M., & Deppe, T., DVM,
enzyme-activities-may-increase-dogs-receiving-corticosteroids
Plumb, D. C. (2011). Ketamine. In Plumb's Veterinary Handbook (7th ed., pp. 568-572).
Plumb, D. C. (2011). Diazepam. In Plumb's Veterinary Drug Handbook (7th ed., pp. 304-
Rezende, M., DVM, PhD, DACVAA, & Mama, K., DVM, DACVAA. (2015, January).
http://www.cliniciansbrief.com/sites/default/files/attachments/ASK_Anesthesia%
20in%20Hepatic%20Disease.pdf