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In Tibetan it is known as དར་་དན་འ་ (ZYPY: yartsa gunbu, Wylie: dbyar rtswa dgun 'bu, "summer grass
winter bug"), which is the source of the Nepali याशागुबा, yarshagumba, yarchagumba or yarsagumba. The
transliteration in Bhutan is Yartsa Guenboob. It is known as keera jhar, keeda jadi, keeda ghas or 'ghaas
fafoond in Hindi. Its name in Chinese Dōng chóng xià cǎo (冬蟲夏草) means "winter worm, summer grass"
(i.e., "worm in the winter, [turns to] plant in the summer"). The Chinese name is a literal translation of the original
Tibetan name, which was first recorded in the 15th Century by the Tibetan doctor Zurkhar Namnyi Dorje. In
colloquial Tibetan Yartsa gunbu is often shortened to simply "bu" or "yartsa".
In traditional Chinese medicine, its name is often abbreviated as chong cao (蟲草 "insect plant"), a name that
also applies to other Cordyceps species, such as C. militaris. In Japanese, it is known by the Japanese reading
of the characters for the Chinese name, tōchūkasō (冬虫夏草).
Strangely, sometimes in Chinese English language texts Cordyceps sinensis is referred to as aweto [Hill H. Art.
XXXVI: The Vegetable Caterpillar (Cordiceps robertsii). Transactions and Proceedings of the Royal Society of
New Zealand 1868-1961. Vol 34, 1901;396-401], which is the Māori name for Cordyceps robertsii, a
species from New Zealand.
The English term "vegetable caterpillar" is a misnomer, as no plant is involved. "Caterpillar fungus" is a preferable
term.
Natural history
The caterpillars prone to infection by the fungus which live underground in alpine grass and shrublands on the
Tibetan Plateau and the Himalayas at an altitude between 3,000 and 5,000 m (9,800 and 16,000 ft). Spending
up to five years underground before pupating, the Thitarodes caterpillar is attacked while feeding on roots. It is
not certain how the fungus infects the caterpillar; possibly by ingestion of a fungal spore or by the fungus
mycelium invading the insect through one of the insect's breathing pores. The fungus invades the body of the
caterpillars, filling its entire body cavity with mycelia, a sclerotium and eventually killing and mummifying the host.
The caterpillars die near the tops of their burrows. The dark brown to black fruiting body (or mushroom)
emerges from the ground in spring or early summer, always growing out of the forehead of the caterpillar. The
long, usually columnar fruiting body reaches 5–15 cm above the surface and releases spores.
In Nepal caterpillar fungus is found on the subalpine pastures in Dolpa in Karnali Zone and Darchula in
Mahakali zone. It is also common in Bhutan and India's Himachal Pradesh and Uttarakhand Himalayas. Reports
of distribution outside of "High Asia" are erroneous and relate to species of Cordyceps, e.g. Cordyceps
militaris.
Use in medicine
Traditional Asian medicines
Medicinal use of the caterpillar fungus apparently originated in Tibet and Nepal. So far the oldest known text
documenting its use was written in the late fourteen hundreds by the Tibetan doctor Zurkhar Nyamnyi Dorje
(Wylie: Zur mkhar mnyam nyid rdo rje)[1439-1475]) in his text:
Man ngag bye ba ring bsrel ("Instructions on a Myriad of
Medicines"). A translation is available at Winkler.[8]
According to Bensky et al. (2004), laboratory-grown C. sinensis mycelia have similar clinical efficacy and less
associated toxicity. He notes a toxicity case of constipation, abdominal distension, and decreased peristalsis,
two cases of irregular menstruation, and one case report of amenorrhea following ingestion of tablets or capsules
containing C. sinensis. In Chinese medicine C. sinensis is considered sweet and warm, entering the lung and
kidney channels; the typical dosage is 3–9 grams.[11]
Research
A March 2013 study on Cordyceps Sinensis documented the medicinal fungus' anti-inflammatory properties.[20]
A March 2013 study on Cordyceps Sinensis documented the medicinal fungus' anti-inflammatory properties.[20]
Scientists were able to show Cordyceps Sinensis' ability to suppress interleukin-1b and interleukin-18 secretion
by inhibiting both canonical and non-canonical inflammasomes. Inflammasomes have long been associated with
auto-inflammatory diseases, such as gout. The study used a specific anamorphic mycelial form of Cordyceps
Sinensis known as Hirsutella Sinensis.
According to Daniel Winkler, the price of Ophiocordyceps sinensis has risen dramatically on the Tibetan
Plateau, basically 900% between 1998 and 2008, an annual average of over 20% (after inflation). However, the
value of big sized caterpillar fungus has increased more dramatically than smaller size Cordyceps, regarded as
lower quality.[9]
Year % Price Increase Price/kg (Yuan)
1980s 1,800
1997 467% (incl. inflation) 8,400
2004 429% (incl. inflation) 36,000
2005 10,000–60,000
2013 125,000–500,000
Because of its high value, inter-village conflicts over access to its grassland habitats has become a headache for
the local governing bodies and in several cases people were killed. In November 2011, a court in Nepal
convicted 19 villagers over the murder of a group of farmers during a fight over the prized aphrodisiac fungus.
Seven farmers were killed in the remote northern district of Manang in June 2009 after going to forage for
Yarchagumba. [24]
Its value gave it a role in the Nepalese Civil War, as the Nepalese Maoists and government forces fought for
control of the lucrative export trade during the June–July harvest season.[25] Collecting yarchagumba in Nepal
had only been legalised in 2001, and now demand is highest in countries such as China, Thailand, Vietnam,
Korea and Japan. By 2002, the herb was valued at R 105,000 ($1,435) per kilogram, allowing the government
to charge a royalty of R 20,000 ($280) per kilogram.
The search for Ophiocordyceps sinensis is often perceived to pose a threat to the environment of the Tibetan
Plateau where it grows. While it has been collected for centuries and is still common in such areas, current
collection rates are much higher than in historical times.
Ophiocordyceps producers like to perpetuate the story that unscrupulous harvesters insert twigs into the
ascocarps of wild C. sinensis to increase their weight and therefore the price paid. A tiny twig is only used when
the ascocarp is broken from the caterpillar, and has nothing to do with artificially increasing weight. Supposedly,
at some point in the past, someone inserted lead wires with which to increase weight; however, each year
hundreds of millions of specimens are harvested and this appears to have been a one-time
occurrence.[citation needed]
Cultivated C. sinensis mycelium is an alternative to wild-harvested C. sinensis, and producers claim it may offer
improved consistency. Artificial culture of C. sinensis is typically by growth of pure mycelia in liquid culture (in
China) or on grains (in the West). The first time in Vietnam, Prof. Aca. Dr. Dai Duy Ban together with scientists
and DAIBIO Company and DAIBIO Great Traditional Medicine Family Clinic discovered the Cordyceps
sinensis as Isaria cerambycidae N.SP. to develop Fermentation DAIBIO Cordyceps Sinensis.[26] Ascocarps
are not produced through in vitro cultivation.
Portrayal in documentary
Caterpillar fungus and its effects on nomads that gather and sell it in Tibet is featured in the 2010
documentary film Summer Pasture.
References
1. ^ "Ophiocordyceps sinensis (Berk.) G.H. Sung, J.M. Sung, Hywel-Jones & Spatafora 2007"
(http://www.mycobank.org/MycoTaxo.aspx?Link=T&Rec=504340). MycoBank. International Mycological
Association. Retrieved 2011-07-19.
2. ^ Halpern, Miller (2002). Medicinal Mushrooms. New York, New York: M. Evans and Company, Inc. pp. 64–
2. ^ Halpern, Miller (2002). Medicinal Mushrooms. New York, New York: M. Evans and Company, Inc. pp. 64–
65. ISBN 0-87131-981-0
3. ^ http://www.npr.org/2011/10/09/141164173/caterpillar-fungus-the-viagra-of-the-himalayas
4. ^ a b Rajesh Kumar, P.S. Negi, Bhagwat Singh, Govindasamy Ilavazhagan, Kalpana Bhargava, Niroj Kumar
Sethy (2011). "Cordyceps sinensis promotes exercise endurance capacity of rats by activating skeletal muscle
metabolic regulators". Journal of Ethnopharmacology 136: 260–266.
5. ^ Berkeley MJ. (1843). "On some entomogenous Sphaeriae" (http://biodiversitylibrary.org/page/783487).
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7. ^ Sung GH, Hywel-Jones NL, Sung JM, Luangsa-Ard JJ, Shrestha B, Spatafora JW. (2007). "Phylogenetic
classification of Cordyceps and the clavicipitaceous fungi". Studies in Mycology 57: 5–59.
doi:10.3114/sim.2007.57.01 (http://dx.doi.org/10.3114%2Fsim.2007.57.01). PMC 2104736
(//www.ncbi.nlm.nih.gov/pmc/articles/PMC2104736). PMID 18490993
(//www.ncbi.nlm.nih.gov/pubmed/18490993).
8. ^ Winkler D. (2008). "The mushrooming fungi market in Tibet exemplified by Cordyceps sinensis and
Tricholoma matsutake" (http://www.thlib.org/collections/texts/jiats/#jiats=/04/winkler/). Journal of the
International Association of Tibetan Studies. In: In the Shadow of the Leaping Dragon: Demography,
Development, and the Environment in Tibetan Areas (4).
9. ^ a b Winkler D. (2008). "Yartsa Gunbu (Cordyceps sinensis) and the fungal commodification of the rural
economy in Tibet AR". Economic Botany 62 (3): 291–305. doi:10.1007/s12231-008-9038-3
(http://dx.doi.org/10.1007%2Fs12231-008-9038-3).
10. ^ Wu Y (1757). "Ben cao cong xin" - "New compilation of materia medica" (in Chinese).
11. ^ Bensky D, Gamble A, Clavey S, Stöger E, Bensky L. Lai (2004). Materia Medica: Chinese Herbal Medicine
(3rd ed.). Seattle, Washington: Eastland Press. ISBN 978-0-939616-42-8.
12. ^ Liu W-C, Wang S-C, Tsai M-L, Chen, M-C, Wang Y-C, Hong J-H, McBride WH, Chiang C-S. (2006).
"Protection against radiation-induced bone marrow and intestinal injuries by Cordyceps sinensis, a Chinese
herbal medicine". Radiation Research 166 (6): 900–907. doi:10.1667/RR0670.1
(http://dx.doi.org/10.1667%2FRR0670.1). PMID 17149981 (//www.ncbi.nlm.nih.gov/pubmed/17149981).
13. ^ Ko WS, Hsu SL, Chyau CC, Chen KC, Peng RY. (July 2009). "Compound Cordyceps TCM-700C exhibits
potent hepatoprotective capability in animal model". Fitoterapia 81 (1): 1–7. doi:10.1016/j.fitote.2009.06.018
(http://dx.doi.org/10.1016%2Fj.fitote.2009.06.018). PMID 19596425
(//www.ncbi.nlm.nih.gov/pubmed/19596425).
14. ^ Nishizawa K, Torii K, Kawasaki A, et al. (2007). "Antidepressant-like effect of Cordyceps sinensis in the
mouse tail suspension test". Biological and Pharmaceutical Bulletin 30 (9): 1758–62. doi:10.1248/bpb.30.1758
(http://dx.doi.org/10.1248%2Fbpb.30.1758). PMID 17827735 (//www.ncbi.nlm.nih.gov/pubmed/17827735).
15. ^ Kiho T, Hui J, Yamane A, Ukai S. (1993). "Polysaccharides in fungi. XXXII. Hypoglycemic activity and
chemical properties of a polysaccharide from the cultural mycelium of Cordyceps sinensis". Biological and
Pharmaceutical Bulletin 16 (12): 1291–3. doi:10.1248/bpb.16.1291
(http://dx.doi.org/10.1248%2Fbpb.16.1291). PMID 8130781 (//www.ncbi.nlm.nih.gov/pubmed/8130781).
16. ^ Kiho T, Yamane A, Hui J, Usui S, Ukai S. (1996). "Polysaccharides in fungi. XXXVI. Hypoglycemic activity
of a polysaccharide (CS-F30) from the cultural mycelium of Cordyceps sinensis and its effect on glucose
metabolism in mouse liver". Biological and Pharmaceutical Bulletin 19 (2): 294–6. doi:10.1248/bpb.19.294
(http://dx.doi.org/10.1248%2Fbpb.19.294). PMID 8850325 (//www.ncbi.nlm.nih.gov/pubmed/8850325).
17. ^ Zhao CS, Yin WT, Wang JY, et al. (2002). "CordyMax Cs-4 improves glucose metabolism and increases
insulin sensitivity in normal rats". Journal of Alternative and Complementary Medicine 8 (3): 309–14.
doi:10.1089/10755530260127998 (http://dx.doi.org/10.1089%2F10755530260127998). PMID 12165188
(//www.ncbi.nlm.nih.gov/pubmed/12165188).
18. ^ Lo HC, Tu ST, Lin KC, Lin SC. (2004). "The anti-hyperglycemic activity of the fruiting body of Cordyceps in
diabetic rats induced by nicotinamide and streptozotocin". Life Sciences 74 (23): 2897–908.
doi:10.1016/j.lfs.2003.11.003 (http://dx.doi.org/10.1016%2Fj.lfs.2003.11.003). PMID 15050427
(//www.ncbi.nlm.nih.gov/pubmed/15050427).
19. ^ Li SP, Zhang GH, Zeng Q, et al. (2006). "Hypoglycemic activity of polysaccharide, with antioxidation,
isolated from cultured Cordyceps mycelia". Phytomedicine 13 (6): 428–33. doi:10.1016/j.phymed.2005.02.002
(http://dx.doi.org/10.1016%2Fj.phymed.2005.02.002). PMID 16716913
(//www.ncbi.nlm.nih.gov/pubmed/16716913).
(//www.ncbi.nlm.nih.gov/pubmed/16716913).
20. ^ Huang, T. et al. (March 2013). "Hirsutella sinensis mycelium suppresses interleukin-1b and interleukin-18
secretion by inhibiting both canonical and non-canonical inflammasomes."
(http://www.tonicology.com/articles/cordyceps-sinensis-hirsutella-sinensis-anti-inflammatory-clinical-
study.pdf) (PDF). Scientific Report. 3, 1374;.
21. ^ Winkler, D. (2009). "Caterpillar Fungus (Ophiocordyceps sinensis) Production and Sustainability on the
Tibetan Plateau and in the Himalayas" (http://app.quickblogcast.com/files/4/6/3/9/3/248966-
239364/Winkler_Cordyceps_ICTAM_Bhutan.pdf). Asian Medicine 5 (2): 291. doi:10.1163/157342109X568829
(http://dx.doi.org/10.1163%2F157342109X568829).
22. ^ Sharma S. (2004). "Trade of Cordyceps sinensis from high altitudes of the Indian Himalaya: Conservation and
biotechnological priorities" (http://www.ias.ac.in/currsci/jun252004/1614.pdf) (PDF). Current Science 86 (12):
1614–9.
23. ^ Jeffrey, Craig (2012-07-07). "The 'Viagra' transforming local economies in India"
(http://www.bbc.co.uk/news/magazine-18735544). BBC News. Retrieved July 9, 2012.
24. ^ Staff (14 November 2011) 'Himalayan viagra': Six men get life for Nepal murders
(http://www.bbc.co.uk/news/world-asia-15741813) BBC News Asia, Retrieved 9 July 2012
25. ^ Baral N, Heinen JT. (2005). "The Maoist people's war and conservation in Nepal". Politics and the Life
Sciences 24 (1): 2–11. doi:10.2990/1471-5457(2005)24[2:TMPWAC]2.0.CO;2
(http://dx.doi.org/10.2990%2F1471-5457%282005%2924%5B2%3ATMPWAC%5D2.0.CO%3B2).
26. ^ DAIBIO Cordyceps Sinensis in Vietnam (http://daibio.com.vn/en/index.php?
option=com_content&view=category&layout=blog&id=250&Itemid=444)
Further reading
Winkler, D. 2005. Yartsa Gunbu - Cordyceps sinensis. Economy, Ecology & Ethno-mycology of a
Fungus Endemic to the Tibetan Plateau. In: A.BOESI & F. CARDI (eds.). Wildlife and plants in
traditional and modern Tibet: Conceptions, Exploitation and Conservation. Memorie della Società Italiana
di Scienze Naturali e del Museo Civico di Storia Naturale di Milano, Vol. 33.1:69–85.
Zhang Y., Zhang S., Wang M., Bai F. & Liu X. (2010). "High Diversity of the Fungal Community
Structure in Naturally-Occurring Ophiocordyceps sinensis". PLoS ONE 5(12): e15570.
doi:10.1371/journal.pone.0015570 (http://dx.doi.org/10.1371%2Fjournal.pone.0015570).
External links
Yartsa Gunbu (Cordyceps sinensis) in Tibet (http://mushroaming.com/Yartsa_Gunbu_Cordyceps)
Daniel Winkler's Cordyceps blog (http://mushroaming.com/blogs/cordyceps)
Nepal's Nature - The Himalayan Viagra (http://www.raonline.ch/pages/np/nat/np_yarcha01.html)
Page at Everything2.com (http://www.everything2.com/index.pl?node_id=1747757)
Image gallery of Cordyceps sinensis
(http://fruit.naro.affrc.go.jp/kajunoheya/epfdb/Ascomy/Cordyc/pqrst/C_sinen.htm)
The first time in Vietnam, Prof.Aca.D.Sc Dai Duy Ban with his scientists discovered Cordyceps Sinensis
as Isaria cerambycidae N.SP. and Fermentation Daibio Cordyceps Sinensis by Daibio Great Family
Traditional Medicine Clinic Company (http://www.cimsi.org.vn/CIMSI.aspx?
action=Detail&MenuChildID=210&Id=3497)
Daibio Cordyceps Sinensis in Vietnam (http://daibio.com.vn/en/index.php?
option=com_content&view=category&layout=blog&id=250&Itemid=444)
An Electronic Monograph of Cordyceps and Related Fungi (http://cordyceps.us)
Cordyceps (http://www.drugs.com/npp/cordyceps.html) information from Drugs.com
Cordyceps sinensis (Berk.) Sacc. (http://libproject.hkbu.edu.hk/was40/detail?
lang=en&channelid=1288&searchword=herb_id=D00019) Medicinal Plant Images Database (School of
Chinese Medicine, Hong Kong Baptist University) (English) (traditional Chinese)
Chinese Caterpiller Fungus (http://libproject.hkbu.edu.hk/was40/outline?
page=1&channelid=44273&searchword=Chinese+Caterpiller+Fungus+&sortfield=%2Bname_chi_sort
&ispage=yes&trslc=50332635.1324208299.1) Chinese Medicine Specimen Database (School of
Chinese Medicine, Hong Kong Baptist University) (English) (traditional Chinese)
Tibet’s Golden “Worm” (http://ngm.nationalgeographic.com/2012/08/tibetan-mushroom/finkel-text)
August 2012 National Geographic (magazine)