STEP 1: Install the Software (look for PL2303 file on CD)
First, install the driver for your version of Windows Note: there are separate drivers for Windows XP and Windows Vista
STEP 2: Plug-in the Hardware
Connect the USB-to-serial adapter to your PC's USB port, and follow the on-screen instructions
STEP 3: Set the Right COM Port
Right click on MY COMPUTER then click PROPERTIES Click HARDWARE, then DEVICE MANAGER Double click PORTS (COM & LPT), and look for PROLIFIC USB- to-SERIAL Com Port Double click that to open it Then click PORT SETTINGS, then ADVANCED Change the COM PORT NUMBER to COM1(or any other com port not in use) Then click OK If you get a warning message, click YES Then click OK, and close DEVICE MANAGER Finally, restart your PC