PEBC PHARMACIST EVALUATING EXAMINATION

REFERENCE SHEET

The following formulas are provided for your reference. They do NOT need to be memorized,
as they will be provided in the Examination Booklets.

- kt kt
log C = log C0 -
C  C0  10
2.303
2.303

C  C0  e-kt ln C = ln C0 - kt

Cave = AUC0Ƭ ClH = Q x fuClint

Ƭ fuClint + Q

0.693 C0
t1/ 2 = t1/ 2 =
k 2k

0.105 0.1 C0
t 90 = t 90 =
k k

Amount absorbed FD A0
Clt = 
or  Vd =
AUC 0 AUC 0 C0

R0 Cl = Vdk
Css =
kVd

C = R 0 (1  e kt ) k = logC1 – logC2

kVd 2.303 t2 – t1

F = AUCoral/D
AUCIV/D
100
For weak acids, percent ionization =
1  antilog (pKa - pH)

100
For weak bases, percent ionization =
1  antilog (pH - pKa )