Professional Documents
Culture Documents
10 MCQ
10 MCQ
benzodiazepine
phenothiazine
butyrophenone
diphenylbutylpiperidine
Tetracaine
Mepivacaine
Lignocaine
Bupivacaine
Psyllium
Polycarbophil
Phenolphthalein
Docusate sodium
Carbamazepine
Cimetidine
Phenobarbital
Smoking
0.5 g in 1 mL
0.5 g in 1 Litre
0.5 g in 100 mL
5g in 100 mL
at room temperature
at 2 - 8 C
at -4 C
at -25 C
8. Pyrogens are;
derivatives of pyrogallol
Lead
Lithium
Gold
Platinum
The effects observed following systemic administration of levodopa in the treatment of Parkinsonism
have been attributed to its catabolism to dopamine. Carbidopa, can markedly increase the proportion of
levodopa that crosses the blood-brain barrier by:
non-linear kinetics
Datura stramonium
Erythroxylum coca
Duboisia myoporoides
Lobelia inflata
In nucleophilic aliphatic substitution reactions the ability of the following leaving groups:(P)
Fluoride (Q) Iodide (R) Chloride (S) Bromide follows the order
P>Q>R>S
R>S>Q>P
Q>S>R>P
P>R>S>Q
In sequence rules, the priority of the following atoms attached to chiral carbon is to be decided for
designating its absolute configuration:
(P) Oxygen (Q) Carbon (R) Nitrogen (S) Hydrogen Priority of the atoms is to be decided on
the basis of their:
electronegativity
atomic mass
atomic number
atomic size
In the four major constituents of vitamin B complex, thiamine, riboflavin, pyridoxal and cynocobalamine:
(p) riboflavin contains ribose sugar ; (q) thiamine contains pyridine ring ;(r) pyridoxal contains
pyrimidine ring ; (s) cynacobalamine contains porphyrin ring The given statement is correct:
Microscopic Technique
pfiser tester
Strong Cobb
Erweka tester
5-6
2.5
28-32
10
10. Aspartame has the main disadvantage as
Carcinogenic
Hygroscopic in nature
Which filler can NOT be used for the preparation of tablets for amine containing basic drugs to avoid
discoloration of the tablets?
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Dicalcium Phosphate
Microcrystalline cellulose
Starch
Lactose
The ability of human eye using illuminated area to detect a particle limited to
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0.4 micron
50 micron
10 micron
25 micron
What quantities of 95% v/v and 45% v/v alcohols are to be mixed to make 800ml of 65% v/v alcohol?
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anti-microbial agent
in-situ emulsifier
antioxidant
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Jaborandi
Rhubarb
Stramonium
Brahmi
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Mayer's Reagent
Dragendroff's reagent
Picric acid
Millon's reagent
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Senna
Digitalis
Belladonna
Coca
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Scrophulariaceae
Leguminosae
Polygalaceae
Rubiaceae
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Datura stramonium
Erythroxylum coca
Duboisia myoporoides
Lobelia inflata
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Commiphora molmol
Boswellia serrata
Commiphora wightii
Commiphora abyssinica
An example of N-glycoside is
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Adenosine
Sinigrin
Rhein-8-glucoside
Aloin
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94,000 spores
92,000 spores
90,000 spores
91,000 spores
Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C
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Aliskiren acts by
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Potassium
Quinidine
Diuretics
Antacids
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LDL-receptor concentration
VLDL secretion
Co-enzyme A formation
Which one of the following drugs is withdrawn from the market due to torsade de pointes?
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Chlorpromazine
Astemizole
Haloperidol
Domperidone
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Cytomegalovirus
Candida albicans
Hepatits B Virus
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Norfloxacin - Metronidazole
Alprazolam - Paracetamol
Cisapride - Omeprazole
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Sulphonamides
Macrolides
Penicillins
Tetracyclines
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Phthalic anhydride
Terephthalic acid
Phthalamic acid
Phthalimide
The common structural feature amongst the three categories of anticonvulsant drugs barbiturates,
succinimides and hydantoins is
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Ureide
Imidazolidinone
Dihydropyrimidine
Tetrahydropyrimidine
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Atropine
Carvedilol
Neostigmine
d-tubocurarine
Chemical nomenclature of procaine is
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2-Diethylaminoethyl 4-aminobenzoate
N, N-Diethyl 4-aminobenzoate
4-Aminobenzamidoethyl amine
4-Amino-2-diethylaminoethyl benzoate
Barbiturates with substitution at the following position possess acceptable hypnotic activity :
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1,3-Disubstitution
5,5-Disubstitution
1,5-Disubstitution
3,3-Disubstitution
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Imipramine
Iproniazide
Fluxetin
Naphazoline
Proton pump inhibitors like omiprazole and lansoprazole contain the following ring system:
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Pyrimidine
Benzimidazole
Benzothiazole
Oxindole
A metabolite obtained from Aspargillus terreus that can bind very tightly to HMG CoA reductase enzyme
is ________
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Fluavastatin
Cerivastatin
Lovastatin
Somatostatin
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An endoperoxide
An exoperoxide
An epoxide
An acid hydrazide
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PDA detector
Electrochemical Detector
Fluorescence detector
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Accuracy expresses the correctness of measurement
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In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelength lower
than
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350 nm
200 nm
300 nm
250 nm
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X-Ray diffractometry
Solution calorimetry
Thermogravimetric analysis
In Gas-Liquid chromatography, some of the samples need to be derivatized in order to increase their
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volatility
solubility
thermal conductivity
polarizability
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particle size
particle volume
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bi-exponentially
trii-exponentially
non-exponentially
mono-exponentially
The temperature condition for storage of drug products under cold temperature is given as :
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α-Chymotrypsin
Hemoglobin
Insulin
Myoglobin
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Nitrocellulose
Polylactic acid
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Sheep blood
Meice lymph
Horse plasma
Fertile eggs
A drug (200mg dose) administered in tablet form and as IV injection (50 mg dose) showed AUC of 100
and 200 microgram hr/mL respectively, The absolute availability of the drug through oral administration
is :
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125 %
250 %
12.5 %
1.25 %
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Phase I
Phase II
Phase III
Phase IV
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Manufacturing area
Aseptic area
Clean area
Ware area
Many mL of a 1:500 w/v stock solution should be used to make 5 liters of 1:2000 w/v solution?
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750 mL
1000 mL
1250 mL
1500 mL
The Volume of distribution of a drug administered at a dose of 300 mg and exhibiting 30 microgram/mL
instantaneous concentration in plasma shall be
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10 L
100 L
1.0 L
0.10 L
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600 mg
300 mg
30 mg
60 mg
Which one of the following is NOT an ex-officio member of Pharmacy Council of India?
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In which of the following technique the sample is kept bellow triple point?
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Lyophilization
Spray drying
Spray congealing
Centrifugation
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Pyridoxine
Thiamine
Nicotinic acid
Inositol
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Expectorent acitivity
Antidepressent activity
Sildenafil is used for the treatment of the following disoders:
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Systolic hypertension
Unstable angina
Pulmanary Hypertension
Cadiac glycosides have the following configuration in the aglycone part of the steroid nucleus :
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5α, 14α
5α, 14β
5β, 14α
5β, 14β
Eugenol is present in
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Fennel
Tulsi
Cardamom
Corriander
whiich one of the following drug is prescribed for the treatment of Philadelphia chromasome positve
patients with Chronic myeloid Leukemia
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Pantostatin
Methotrexate
Imatinib
L-Asparaginase
Which of the following monochlonal antibodies is prescribed for patients with non-Hodgkin's
Lymphoma?
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Infiximab
Abciximab
Gemetuzumab
Rituximab
Identify the drug which is not used in the treatment of Malaria caused by Plasmodium falciparum
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Artemisinin
Primaquine
Quinine
Mefloquine
Which one of the following drugs does NOT act through G-Protien coupled receptors
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Epinephrine
Insulin
Dopamine
TSH
Which one of the following drugs is most effective in preventing transmission of HIV from the mother to
foetus?
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Lamivudine
Zudovudine
Indinavir
Ribavirin
Improvement of memory in Alzheimer's disease is brought about by durgs which increase transmition in
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Cholinergic Receptors
Dopaminergic Receptors
GABAergi Receptors
Adrenergic Receptors
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Piroxicam
Celecoxib
Nebumetone
Ketorolac
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Chlorpromazine
Haloperidol
Resperidone
Flupentixol
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Donepezil
Edrophonium
Atropine
Pancuronium
Which one of the following drugs specially inhibits calcineurin in the activated T Lymphocytes?
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Daclizumab
Prednisone
Sirolimus
Tacrolimus
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Acidic
Basic
neutral
amphoteric
which one of the followingis used as a mood stabilizer for bipolar disorders and also in certain epilieptic
convulsions?
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Phenytoin
Lithium
Sodium valproate
Fluoxetine
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Pyrrole
isoxazole
phenol
Tetrazole
For glyburide, all of the following metabolic reactions are logical EXCEPT
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O-demethylation
aromatic oxidation
benzylic hydroxylation
amide hydrolysis
The effects observed following systemic administration of levodopa in the treatment of Parkinsonism
have been attributed to its catabolism to dopamine. Cabidopa, can markedly increase the propotion of
levodopa that cross the blood-brain barrier by
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A compound will be sensitive towards IR radiation only when one of the following properites undergo
transition on radiation
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Polarizability
Dielectric constant
Dipole moment
Refractivity
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Optical rotatory despersive power
Absolute configuration
Relative configuration
Optical purity
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A singlet or triplet state may result when one of the electrons from the HOMO is excited to higher
energy levels
In an excited singlet state, the spin of the electron in the higher energy orbital is paired with the
electron in the ground state orbital
Triplet excited state is more stable than the singlet excited state
When the electron from the singlet excited state returns to ground state, the molecule always shows
fluorescence phenomenon
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Niacinamide
Vitamin B12
Pyridoxal Phosphate
Thiamine
Purity of water can be assessed by determining one of its following properties instrumentally :
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pH
Refractivity
Viscosity
Conductivity
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Carbon NMR is less sensitive than Proton NMR
In the TCA cycle, at which of the following ezyme-catalyzed steps, incorporation of elements of water
into an intermediate of the cycle takes place :
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Citrate synthase
Aconitase
Malate dehydrogenase
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complex formation
In the mixing of thymol and menthol the following type of incompatibility occurs :
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Chemical incompatibility
Therapeutic incompatibility
Physical incompatibility
Tilerance incompatibility
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Lactose
Ampoules
Hardness of tablets
Gelatin
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In the Drugs and Cosmetics Act and Rules, the Schedule relating to GMP is
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Schedule M
Schedule C
Schedule Y
Schedule H
Thioglycolic acid-like compounds have applications in the following type of cosmetic formulations :
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Depilatory preparations
Epilatory preparations
Vanishing creams
Which one of the following is a flocculating agent for negatively charged drug?
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Aluminium chloride
Bentonite
Tragacanth
Sodium biphosphate
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soft paraffin
urea
bees wax
steryl alcohol
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Highly branched three dimenssional macromolecules with controlled structure with all bonds originating
from a central core are known as
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Cyclodextrins
dextrans
dendrimers
liposomes
Which one of the following is the commonly used bulking agent in the formulation of freeze dried low
dose drug products
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sodium chloride
mannitol
starch
HPMC
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Dissolution rate
Dose uniformity
Stability
Dissolution rate
3. Modified starch is
Starch 1500
Starch 1000
Starch 200
Starch 1200
Talc
Hydrogenated vegitable oils
Magnesium stearate
Boric acid
2-15% w/v
1-5% w/v
0.5-3% w/v
Lactose
Mannitol
Methyl Cellulose
Acacia
Microscopic Technique
pfiser tester
Strong Cobb
Erweka tester
5-6
2.5
28-32
10
Carcinogenic
Hygroscopic in nature
Indian baladona is
Atropa Belladonna
Atropa fastusa
Atropa succirubra
Meconic acid
Starch
Calcium Oxalate
Tannins
Bitterness value
Hemolytic activity
Swelling Index
4. White ginseng is
Washed roots without secondary roots, sun dried and oftenly peeled
Antimalarial agents
Antiamoebic agents
Antifungal agents
Appetizing agents
Soxhlet apparatus
Perculator
Clavenger apparatus
Morphine
Codiene
Thebaine
Papaverine
Gums
Guggulsterol I and II
Guggulsterones E and Z
Digoxin
Sennoside A
Aloin
Sinigrin
Tryptophan
Secologanin
Ornithine
Reticuline
Quinine and Quindine are dextrorotatory, cinchonine and cinchonidine are levorotatory
Quinine and Quindine are levorotatory, cinchonine and cinchonidine are dextrorotatory
Quinine and cinchonidine are levorotatory, Quindine and cinchonine are dextrorotatory
Quinine and cinchonine are dextrorotatory, Quindine and cinchonidine are levorotatory
Ornithine
Tryptophan
Tyrosine
Phenylalanine
4. Ergotoxine is a mixture of
2 alkaloids
3 alkaloids
4 alkaloids
6 alkaloids
5. The active constituents of cassia bark consists of all of the following EXCEPT
Cinnamic acid
Caryophylline
Eugenol
Coumarin
7. Tropane is
6, 7 epoxy tropane
3 α - hydroxy tropine
3 β - hydroxy tropine
3 apatropine
Vitamin C
Vitamin Y
Vitamin P
Vitamin M
S - Glycosides
O - Glycosides
C - Glycosides
N - Glycosides
Baljest test
Legal test
Phenobarbital
Barbitone
Thiopentanal
Pentobarbital
2. Hydrolysis of methoxy carbonyl and Benzoate group of cocaine gives an inactive compound which is
known as
Ecgonine
Tropacocaine
Atropine
Pseudo cocaine
N - Methyl Group
- Cl group
- OC2H2 group
- OCH3 Group
Diclofenac
Flurbiprofen
Sulindac
Indomethacin
Benzene
Naphthalene
Anthracene
Pyridine
Ester group
Amide Group
Chloro group
Hydroxy group
Sulfinpyrazone
Oxyphenbutazone
Phenazone
Azapropazone
Loop diuretic
ACE inhibitor
Aldosterone antagonist
Diuretic
4 - amino quinoline
8 - amino quinoline
9 - amino quinoline
Acidine
Penicilloic acid
Penaldic acid
Penicillic acid
Penicillamine
Allopurinol
Methotrexate
Cyclophosphamide
Buslphan
Ketotifen
Terbutaline Sulfte
Nedocromil
Sodium Chromoglycate
3. The drug which was used as 'LIE DETECTOR' during the Second world war is
Nitrous Oxide
Chloroquine
Carbamazepine
Hyoscyine
Atropine
Pralidoxime
Pirenzepine
Ipratropium
Sulfasalazine
Mesalazine
Olsalazine
Belladona
Nux vomica
Vinca rosea
Cascara
8. Organic nitrates are not very usefull in acute angina attacks because they
are insoluble
Chloramphenicol
Diphenylhydantoin
Chlorpropamide
Dicumarol
10. Cyanocobalamine is a
Steroid
Choline esterase inhibitor
Hallucinogen
Vitamin
Ethylene diamine
Tripyridyl
Citric acid
EDTA
Chelating agent
Anti oxidant
Solubilizing agent
Oxidising agent
3. The inclusion of water miscible solvents in the formulation will increase the stability by
Supressing ionization
Ointments
Suspositories
Capsules
Solutions
Barbiturates
Sulphonamides
Steroids
DSC
XRD
FTIR
HPLC
pH determination
Solubility determination
8. Kinetic pH profiles for preformulation are mainly done by exposing the drugs to
Base degradation
Acid degradation
Aqueous degradation
Metastable form
Stable form.
Unstable form
Polar solvents
Non polar solvents
Galactomanne
A:-Graphene
B:-Titanium Nanorods
C:-Iron Nanofoils
D:-Copper Nanowires
A:-Diluent
B:-Granulating agent
C:-Glidant
D:-Disintegrating agent