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Cleanroom Technology Handbook PDF
Cleanroom Technology Handbook PDF
Cleanroom Technology
2
Editorial
Festo Singapore
Jiang Hong, Christian Burdin,
Edward Gasper
Festo Germany
Robert Strommer
3
Contents
2.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21
3.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 34
4
Contents
4.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 49
5.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 56
5
Contents
6.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81
7.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91
Keyword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .108
6
1.0 Introduction to Cleanroom
1.1 Introduction of Cleanroom
8
1.2 Definition of Cleanroom
9
1.3 Classification of Cleanrooms
1 35 7.5 3 1 NA
10 350 75 30 10 NA
1000 NA NA NA 1000 7
10000 NA NA NA 10000 70
Table 1.2
10
1.3 Classification of Cleanrooms
Objects Approximate
size (microns)
Human hair 100
Dust 25
Table 1.3
11
1.4 Cleanrooms for Different Industries
Table 1.4
12
1.5 Types of Clean Areas
Fresh
Figure 1.2 is a diagram of a air
Air conditioning
simple conventionally venti-
plant
lated cleanroom. The general
method of ventilation used in Recirculated
this type of cleanroom is similar air
to that found in offices, shops,
Pressure
etc. in that air supplied by an stabilizers
air-conditioning plant through Change
diffusers in the ceiling. area
Cleanroom
Passover
bench
Pass-through grilles
Figure 1.2
13
1.5 Types of Clean Areas
14
1.5 Types of Clean Areas
15
1.5 Types of Clean Areas
Air extract
Figure 1.3
16
1.5 Types of Clean Areas
Air extract
Figure 1.6
Figure 1.7
17
1.5 Types of Clean Areas
High-efficiency
1.5.4 Isolator or minienviron-
air filter ment
Figure 1.9
18
1.5 Types of Clean Areas
19
2.0 Cleanroom Design and Technology
2.1 Introduction
21
2.2 Tasks of Cleanroom Technology
2.3.1 Layout
22
2.3 Design Features
Using this concept, less Service area Service area Service area
expensive cleanrooms have Cleanroom with chases Cleanroom
Cleanroom Minienvironment
been designed in which service
chases with lower environmen-
tal cleanliness standards are
interdispersed with cleanroom
tunnels. Figure 2.2 shows this.
(a) (b) (c)
It is also in the ballroom type of ISO 3 (Class 1) or better ISO 6 (Class 1,000) or worse
design to divide up the ball-
room with prefabricated walls Figure 2.2
and provide clean tunnel and
service chases; these walls can
be dismantled and reassem-
Supply air from fans
bled with different configura-
tion should the need arise.
100 % Hepa ceiling
Figure 2.3 and 2.4 show two Ducted or
typical designs of tunnel and ceiling fan
service chase. These are
Class 1/100 Utility and
designs which have been used equipment
in the past but are still chase
applicable in manufacturing Perforated floor Return
areas or laboratories where air
less than state-of-the-art
components are produced.
Figure 2.3
Ceiling
return
Hepa
30 % ceiling
coverage
Hepa Hepa
Electrical
Equipment Class 100 Class 100
chase Class 1000 Utility
process
piping
Return
air
Figure 2.4
23
2.3 Design Features
24
2.3 Design Features
Supply air
Supply
air
Return
air
Return
air
vertical horizontal
Figure 2.7 Figure 2.8
25
2.3 Design Features
In nonunidirectional airflow
Return
air
cleanrooms, air flows through
HEPA/ULPA filters located in
various positions and is re-
turned through opposite loca-
Supply
air tions. Filters may be distributed
at equal intervals throughout
the cleanroom or grouped over
Turbulent Return air Displacement critical process areas. Because
Figure 2.9
of the distribution of the filters,
air flow may be turbulent in
nature. The degree of turbu-
lence is usually greater than 20.
Return Return
air air
Figure 2.10
26
2.3 Design Features
The layout of mixed air flow The additional air flow makes
cleanrooms should be con- the cleanroom more capable of
sidered even more carefully. recovering from transient
Mixed air flow cleanrooms episodes of particle generation
maintain cleanliness primarily due to activity within it. If flexi-
by dilution, rather than by air bility is defined as the ability to
flow. As a result, areas within modify the entire cleanroom,
the cleanroom that are isolated then fan hoods or modules
from the air path are most likely capable of being easily rear-
to develop high concentration ranged may be used in lieu of
of contamination. a central recirculating system.
27
2.3 Design Features
Class Air flow Average air flow velocity2 Air changes per hour3
Type1
M7 & M6.5 (Class 100,000) NM .005 - .041 m/s (1-8 ft/min) 4 – 48
M6 & M5.5 (Class 10,000) NM .051 - .076 m/s (10-15 ft/min) 60 – 90
M5 & M4.5 (Class 1,000) NM .127 - .203 m/s (25-40 ft/min) 150 – 240
M4 & M3.5 (Class 100) UNM .203 - .406 m/s (40-80 ft/min) 240 – 480
M3 & M2.5 (Class 10) U .254 - .457 m/s (50-90 ft/min) 300 – 540
M2 & M1.5 (Class 1) U .305 - .457 m/s (60-90 ft/min) 360 – 540
M1 & Cleaner U .305 - .508 m/s (60-100 ft/min) 360 – 600
1When air flow type is listed, it re- 2 Average air flow velocity is the 3Air changes per hour are the way
presents the more common airflow way that air flow is standard dimen- that nonunidirectional and mixed
characteristics for cleanrooms of sion cleanrooms (i.e. those that air flow in nonstandard, high bay, or
that class: U = unidirectional; typically have a ceiling height of 10 unusually configured cleanrooms
N = nonunidirectional; M = mixed feet or 3 metres) usually is speci- usually is specified. Air flow velocity
fied. This term is commonly used to and air changes per hour are mathe-
refer to unidirectional air flow. matically equivalent methods, the
conversion formula being:
Table 2.1
28
2.3 Design Features
Undirectional
air flow
Nonundirectional
air flow
Figure 2.11
29
2.3 Design Features
Figure 2.11
30
2.3 Design Features
31
2.3 Design Features
32
3.0 Design Principles of Cleanroom Equipment
3.1 Introduction
34
3.2 The Importance of Equipment Design
Modification
➔
Qualification
35
3.3 Influence on air flow pattern
36
3.4 Suitable Materials for Equipment Design
37
3.4 Suitable Materials for Equipment Design
38
3.4 Suitable Materials for Equipment Design
Materials:
•Stainless steel
– chemically or electrochemi-
cally polished
– pickled roughness Ra ‹5 µm
•Eloxed aluminum (thickness
›20 µm)
•Stoved finished quartz
•Glass
•Plastics
– no outgassing of additives
– no out-diffusion of softener:
PTFE, PFA, PVDF, PP
39
3.5 Cleaning Methods
40
3.6 Basic Principles of Equipment Design
The following principles are 3.6.4 Analyzing of ways of 3.6.6 Secondary measures/
used as a guide for equipment gripping products alternatives
design; these are used to
minimize faults in the final If you need to use a gripper in The above five principles are
equipment. the production, avoid gripping required but however, if you are
in the same direction as the not available to meet these
3.6.1 Using rotary moving direction of the first air flow. requirements.
elements Keep the product contact to
a minimum either by the The following are some
Whenever possible rotary equipment or the operator. guidelines, which should be
movements should be considered:
employed, as lesser particles If you grip either from the side •Encapsulating components
are generated by rotary moving or from beneath the product, •All moving parts enclosed
elements. Furthermore, it is the gripper does not affect the •Vacuum suction
easier to seal rotating elements air flow around the product and •Accurately aimed local air flow
from the clean environment. the air flow obstruction caused direction
by the gripper is kept to a
minimum.
3.6.2 Minimizing sliding
friction If the gripper can only be used
above the product, then keep
The design should minimize moving elements next to the
sliding friction. Do not use product and select the shape of
sliding tracks, it is better if you the gripper and its distance
could use roller tracking. Lip away from the product in such
sealing is also not allowed and a way that stagnant areas do
tries to avoid unnecessary not reach the product
functional contact.
41
3.7 Contamination Control of Cleanroom Equipment
42
3.7 Contamination Control of Cleanroom Equipment
43
3.7 Contamination Control of Cleanroom Equipment
44
3.7 Contamination Control of Cleanroom Equipment
45
3.8 Qualification of Cleanroom Equipment
•Correlation of cleanroom
classification/air volume
– air volume
– defined degree of cleanli-
ness per volume of air
•Procedures for classification
standards are related to
cleanrooms
46
3.9 Cleanroom and Cleanliness Suitability
3.9.1 Parameters of
cleanliness suitability Assessment:
in which cleanroom
The following lists out the classes the operating
parameters that affect the materials may be used
cleanliness suitability.
•Airflow patterns
Figure 3.1
•Airborne particulate
contamination
•Finding optimization
potentials
•ESD behaviour
•Quality of surfaces
•Sedimented particle emission
behaviour
•Cleanroom suitability of
material used
•Conception of the operating
materials
•Molecular contamination
•Upholding constructional
device standards (e.g. SEMI)
•Upholding national and
international regulations/
guidelines for cleanliness
47
4.0 Cleanroom Garment System
4.1 Introduction
49
4.2 Cleanroom Garments
50
4.3 Entry and Exit Procedures
51
4.3 Entry and Exit Procedures
52
4.3 Entry and Exit Procedures
53
4.3 Entry and Exit Procedures
54
5.0 International Standard for Cleanrooms
5.1 Introduction
56
5.2 Cleanroom Classes
Cleanroom classification
standards can be divided into
the following subgroups:
Table 5.1
57
5.3 The Present Engineering Classes
These classes are used mainly various editions of the US sion, similar to FS 209. Some
in rooms where electronic and Federal Standard 209. made minor changes of the
engineering items are manu- Some countries completely classes to comply with the met-
factured. Most of these stan- adopted FS 209, while others ric system, but all changed the
dards are based on one of the made their own national ver- denomination of the classes.
ISO Class 1 1
ISO Class 2 2 0
M1
1 ISO Class 3 3 1 C 0.035
M2
10 ISO Class 4 4 2 D 0.35
M3
100 ISO Class 5 5 4,000 3 E, F 3.5
M4
1,000 ISO Class 6 6 – 4 G, H 35
Note: The M values for FS 209E (and M5
the ISO values) are in metric units. 10,000 ISO Class 7 7 40,0000 5 J 350
The M figures are therefore ele- M6
vated above the line of the others, 100,000 ISO Class 8 8 4,000,000 6 K 3500
which are given in cubic feet. M7
FS 209E class 100 therefore corre- ISO Class 9 7 L
sponds to M class 3.5 and ISO 5.
58
5.4 Federal Standard 209E, and its Four Early Editions
Table 5.4
1 35 7.5 3 1 NA
10 350 75 30 10 NA
1,000 NA NA NA 1,000 7
10,000 NA NA NA 10,000 70
Table 5.5
59
5.4 Federal Standard 209E, and its Four Early Editions
5.4.1 Federal Standard 209 – Version E differs from the tions of particles.
Version E previous editions as follows: Table shows the class limits of
• The cleanroom classes are the classroom in terms of the
A substantially changed version metric. particle concentration in both
E was published in 1992, with • It has seven classes of metric and the original English
a more precise title: “Airborne cleanliness: M1-M7. units. This table does not
particulate cleanliness classes • It gives a method for necessarily represent the size
for cleanrooms and clean measuring air cleanliness. distribution to be found in any
zones.“ • It demands a plan for particular situation.
monitoring air cleanliness.
• It gives a rational for the Concentration limits can be
statistical rules used. calculated for intermediate
• Ultrafine particles are con- classes, approximately, from
sidered, i.e. particles the equation:
‹0.02 mm.
• It considers iso-anisokinetic particles/m3 = 10M (0.5/d)2.2
sampling.
• It describes sequential Where “M” is the numerical
sampling for low concentra- designation of the class based
on SI units and “d” is the
SI English (m3) (ft3) (m3) (ft3) (m3) (ft3) (m3) (ft3) (m3) (ft3)
Table 5.6
60
5.5 German Standard: VDI 2083
Table 5.7
61
5.6 British Standard: BS 5295
Table 5.8
C 100 35 0 NS NS
D 1,000 350 0 NS NS
E 10,000 3,500 0 NS NS
F NS 3,500 0 NS NS
H NS 35,000 200 0 NS
M NS NS NS 450,000 50,000
NS – No specified limit
Table 5.9
62
5.7 Japanese Industrial Standard: JIS B 9920
63
5.8 Australian Standard: AS 1386
64
5.8 French Standard: AFNOR X 44101
65
5.10 Dutch Standard: VCCN-RL-1
66
5.11 Russian Standard: GOST R 50766-95
67
5.12 ISO Classification Standard
Table 5.10
68
5.12 ISO Classification Standard
ISO 1 10 2
ISO 2 100 24 10 4 8
Table 5.11
69
5.12 ISO Classification Standard
Table 5.12
Table 5.13
70
5.12 ISO Classification Standard
Table 5.14
71
5.13 Summary of FS 209E and ISO 14644-1 and -2
72
5.13 Summary of FS 209E and ISO 14644-1 and -2
Minimum counts/test 20 20
Measurement methods DPC (=OPC, CNC) + optical DPC for 0.1 – 5 mm particles,
microscopy CNC for ultrafines; optical
microscope for macroparticles
Table 5.16
73
5.14 Biocontamination and Pharmaceutical Classes
In the early 1960s, the pharma- The GMP guides deals largely
ceutical industry developed with the methods of good
cleanroom standards to manufacturing but also specify
counteract contamination the building design, building
problems of sterile products material, care of personnel, etc.
which had caused sickness and They also give figures for the
death in patients. cleanliness classes of clean-
rooms: particles, microorgan-is-
It had been realized that as ms, as well as the type of air
only a small sample of drugs filters and number of air
could be tested, a final test of changes per hour.
sterility could never determine
the safety of sterile products. It The GMP guides, produced by
was necessary therefore to rely the various countries, are
on proper manufacturing, i.e. advisory rather than legal and
good manufacturing practice consider that there is more
(GMP). than one way to achieve the
recommended standards. To
These standards are known as check that the GMP is being
Guides to Good Manufacturing applied correctly, each country
Practice (GGMP). They were has government inspectors.
based on experience of the They will interpret the generally
then new FS 209, BS 5295 and expressed statements of the
other engineering standards, as guides. A pharmaceutical
well as the experience in the manufacturer must also comply
manufacture of pharmaceutical with the GMP guides of the
products. countries receiving their
products.
The goal of GGMPs is to care-
fully specify the proper method
of manufacture of sterile prod-
ucts by eliminating microbial
and particle contamination and
hence creating the correct
quality assurance (QA).
74
5.14 Biocontamination and Pharmaceutical Classes
By Year Remarks
Food and Drug Administration (FDA) 1963 first GMP
By Year Remarks
PIC: GMP and Guidelines 1995 valid in European countries outside the
EU and Australia
FDA cGMP
1987 valid for the United States
EU GGMP
1997 valid for the EU area
Table 5.18
75
5.14 Biocontamination and Pharmaceutical Classes
Comparison of Major Pharmacy GMP Guides regarding working conditions and classes
Table 5.19
EU GMP Guide 1997, air particle classification system for the manufacture of sterile products
A 3,500 0 3,500 0
Table 5.20
(a) In order to reach the B, C and D (b) At rest should be received in the (C) Appropriate alert and action
air grades, the number of air unmanned state after the 15-20 min limits should be set for the results
changes should be related to the “clean-up” period. of particulate and microbiological
size of the room and the equipment monitoring. If these limits are
and personnel present in the room. exceeded, operating procedures
The air system should be provided should prescribe corrective action.
with appropriate filters such as
HEPA for grades A, B and C.
76
5.15 ISO Biocontamination Standards: 14698
77
5.15 ISO Biocontamination Standards: 14698
a) Title a) Title
Cleanrooms and associated Cleanrooms and associated
controlled environments – controlled environments –
Biocontamination control. Biocontamination control.
Part 2 – Evaluation and Inter- Part 3 – Measurement of the
pretation of Biocontamination Efficiency of Processes of
Data. Cleaning and/or Disinfection of
Inert Surfaces Bearing Bio-
b) Scope contamination Wet Soiling or
Gives guidance on basic Biofilms.
principles and methodology
requirements for all microbio- b) Scope
logical data evaluation Describes guidance for a
obtained from sampling for laboratory method for
viable particles in specified risk measuring the efficiency of
zones in cleanrooms. cleaning an inert surface.
c) Status c) Status
FDIS (Final Draft International Passed an ISO DIS (Draft
Standard) document is awaiting International Standard) vote in
issue by ISO Geneva for an FDIS July, 1999. Has been
vote by all member ISO nations. subsequently determined to be
too limiting to be issued as an
ISO standard.
78
5.16 The Containment Classes
Table 5.21
79
6.0 Airborne Particle Emission Measurements
6.1 Introduction
81
6.2 Sources of Particles
Aerodyn. sensor
both
Optical counter com-
bined
Light optical microscope
Collec-
Electron microscope tive
method
82
6.3 Optical Particle Counters
6.3.1 A basic particle counter Display, printer and data The most important part of a
interface is available on many particle counter is its sensor,
Airborne particle counters are counters as shown in Figure which uses collected light
sophisticated instruments that 6.1. The vacuum pump pulls scattered from particles. The
measure airborne particles in the sample through the sensor sensor contains a laser light
a number of size ranges which where any particles present are source that illuminates an area
are far too small to be seen, but detected. The counting called the “view volume” with
may have a serious impact on electronics collect, report and intense light. Particles in the
air quality. store the information for use by sample pass through the view
the operator. The counted volume and scatter the laser
Although they come in a wide particles are trapped in an light; just as dust motes or
variety of sizes from heavy exhaust filter and not returned smoke particles do in a
bench top units designed for to the environment from which sunbeam.
semipermanent installation to the sample was taken.
hand-held counters weighing The light is then collected and
less than half a kilogram, all focused onto a photo detector.
counters have the same basic The photo detector converts
components of sensor, vacuum the light signal to electrical
source (for sample flow) and pulses, the height of which is
control electronics. directly proportional to the
particle size.
83
6.3 Optical Particle Counters
84
6.4 LASAIR 210 Optical Particle Counter
The LASAIR particle counter is a The cavity has a resonant Q of 6.4.2 Flow volume
microprocessor-based instru- approximately 100. When it is
ment that detects airborne driven with 10-milliwatt HeNe The flow volume for this counter
particles, analyses and stores laser, a one-watt beam is avail- is 1 ft3/min (cubic foot per min-
the data in eight size classes, able to illuminate particles. ute) or 28.3 litres per minute.
and produces reports. It dis-
plays real-time data on a 5-inch The LASAIR flow system (Figure
CRT and contains a printer, 6.2) provides a sample flow. 6.4.3 Size range
which can be used to produce The system includes a pump,
hard copies of reports. filters, flow meter, inlet jet and The counter is able to detect
outlet jet. The jet tip defines particle size from 0.2 µm to
the size, shape, and position of 5.0 µm.
6.4.1 Working Principle the sample stream in relation to
the laser beam. A purge flow is
The LASAIR sizes and counts drawn across the sample cavity Sample Pump
particles by measuring the mirrors to keep the laser optics block Plumbing
block
amount of light scattered from clean while sampling. Sample
each particle. The source of inlet Filter Outlet
illumination is a 10-milliwatt The collecting optics includes
Purge Differential Bypass valve
HeNe laser. The patented four Mangin mirrors and a inlet Filter pressure sensor to set flow
passive optical cavity is defined solid-state photodetector. The for flow meter
Carbon
by the laser output coupler mirrors are anti-reflective A-R filter
mirror and a mirror-coated coated for minimal light loss. Lasair 110 only
quartz which is part of an One set of mirrors is located on
oscillator. each side of the laser optical Figure 6.2
bench. The collecting optics
The vibration of the crystal provides one-to-one magnifi-
shifts the wavelength of the cation of scattered light to the
reflected light to maximize the detector.
transfer of power into the
external passive cavity while The amplified signal from the
minimizing reflection of photodiode is proportional to
coherent light back into the the size of the particle and the
laser. brightness of the illumination.
This signal is compared to the
reference voltage derived from
the laser light leaked through
the crystal mirror to provide
automatic gain control.
85
6.5 Setting Up of Optical Counters
Probe
volume
Sample
flow rate 100 % 5 – 10 % >80 %
Figure 6.3
b) Partial stream
86
6.5 Setting Up of Optical Counters
When particles are sampled The condition of anisokinetic During the airborne particle
from a flowing air stream, sampling is when the mean emission measurements, the
a difference between the air velocity of the flowing air operating parameters of the
velocity in the stream and the stream differs from the mean OPC are set as follows:
air velocity entering the probe velocity of the air entering the • Air volume: 1.0 ft3/min
inlet can cause a change in inlet of the sampling probe. • Sampling time: 60 seconds
concentration because of • Delay time: 1 second
particle inertia. When these Because of particle inertia, • Measurement time: 5 minutes
velocities are the same, the anisokinetic sampling can
sampling is isokinetic; other- cause the concentration of
wise, the sampling is aniso- particles in the sample to differ
kinetic. from the concentration of
particles in the air being
sampled.
b) Isokinetic
87
6.6 Test Environment Measurements
88
6.6 Test Environment Measurements
89
7.0 Festo Cleanroom Project
7.1 Introduction
91
7.2 Festo’s Collaboration with Fraunhofer and Nanyang Polytechnic
92
7.2 Festo’s Collaboration with Fraunhofer and Nanyang Polytechnic
93
7.3 Test Environment and Test Conditions
Ceiling
Window Hepa
Return panel
air
Utility and
equipment
chase
Return air
plenum Floor
Figure 7.1
94
7.3 Test Environment and Test Conditions
7.3.2 Minienvironment
95
7.3 Test Environment and Test Conditions
Figure 7.3
96
7.3 Test Environment and Test Conditions
97
7.4 Standard Operating Procedure
98
7.4 Standard Operating Procedure
Determination of points of
highest concentrations of 7.4.6 Statistical evaluation
particle emission (according to
VDI 2083 part 8) Evaluation according to
guideline VDI 2083 part 8
• Coarse localization measure-
ment
• Localization measurement 7.4.7 Visual inspection
7.4.8 Classification
Classification according to
statistical evaluation and visual
inspection (see guideline
VDI 2083 part 8)
VDI 2083
99
7.4 Standard Operating Procedure
100
8.0 Cleanroom Products
8.1 Introduction
102
8.2 Reasons
103
8.3 Basic Principles for Cleanroom Products
It is known that there isn’t This principle includes the The above three aspects can be
a standard or guideline for following three aspects: achieved for cleanroom com-
cleanroom product design • Noncontaminant release – patibility by modifying our stan-
available. very low leakage construc- dard products to cleanroom
tion products with some special
In order to develop products for • Noncontaminant generation – features. The general principle
cleanroom application, we special material, surface is to design an additional
mainly base on the principle of treatment and special lubri- vacuum suction port so that air
“avoiding cleanroom contami- cation specification leakage during operation can
nation by preventing particles • Noncontaminant in produc- be sucked back and extracted
generated from the compo- tion processes – component by vacuum.
nents”. cleaning and double bag
packaging
Table 8.1
104
8.4 Production Sequence for Cleanroom Products
8.4.3 Testing
8.4.4 Cleaning
8.4.5 Packaging
105
8.5 Performance of Cleanroom Products
106
8.6 Precautions in Operation
8.6.1 Purification of supply air 8.6.2 Piping 8.6.4 Operating piston speed
For the cleanliness of an Pipes and fitting have a large Piston speed and thus the
application clean dry air is influence on the cleanliness of impact the piston generates
extremely important. To supply an application. Generally when touching the end cap of
clean air, we have set up the air barbed fitting should be a cylinder, is the most crucial
supply as follows: applied whenever possible. parameter concerning particle
Push-pull fitting are not emission. The piston speed
suitable for cleanroom should not exceed 0.2 m/s in
applications, as they tend to order to archive a good
leak. Also, the way, how tubes cleanliness.
are laid, is important for clean
applications of pneumatics. It
should be avoided that tubes 8.6.5 Solenoid valve manifold
rub on any surface.
Whenever possible valves
should not be used in the direct
8.6.3 Notes of set up vicinity of any sensitive
product, although, valves in
The way, how pneumatic general only emits little
components are mounted does particle. It is best to install
not directly influence the valves directly above the floor.
particle emission. However, it is
an important factor to avoid
cross contamination. Meaning,
contamination caused by
particles, which are carried by
the air from a less sensitive
location to a sensitive location.
Grey Room
Cleanroom
Figure 8.1
107
Keyword
Ruiter Strasse 82
D-73734 Esslingen
108