Urdaneta City University: Midwifery Pharmacologic Notes

Urdaneta City University
1 San Vicente West, Urdaneta City, Pangasinan 2428

(075) 568-2475 loc. 8110, Fax: (075) 600-1468
E-mail: ucuschoolofmidwifery@gmail.com
School of Midwifery
Established in 1973
LEVEL II ALCU-COA ACCREDITATION STATUS
MIDWIFERY PHARMACOLOGIC NOTES

DRUG NAME DOSAGE/ INDICATIONS/ SIDE EFFECTS ADVERSE MIDWIFE’S RESPONSIBILITY
ROUTE/ USES EFFECTS
(Generic Name/ FREQUENCY
Brand name, Local Market Price) PRE- INTRA- POST-
ADMINISTRATION ADMINISTRATION ADMINISTRATION
Generic Name: Methergine IV: Prevention and most common hypertension, >Explain the effect of the > Breathing, blood pressure, >Be alert for adverse
0.2 mg after treatment of adverse reaction is temporary chest Methergine to the patient. oxygen levels, and other vital reactions and drug
Brand Name: Methylergonovine delivery of postpartum and post hypertension pain, palpitation, Standard protocol for signs will be watched closely interactions.
Maleate anterior shoulder, abortion hemorrhage associated in several dizziness, seizure, management should be while the patient is receiving > Monitor postpartum
after delivery of caused by uterine cases with seizure headache, nausea, available. Methergine. women for BP changes and
Local Market Price: placenta, or atony or and/or headache. vomiting, diarrhea, > Assess history of allergy > Administer by IM injection amount and character of
during subinvolution Hypotension has foul taste, to the drug. or orally unless emergency vaginal bleeding.
puerperium; may also been reported. thrombophlebitis, >This drug should be used requires IV use. > Avoid prolonged use of the
be repeated as Abdominal pain tinnitus, hematuria, extremely carefully because Complications are more drug.
required at (caused by uterine dyspnea, nasal of its potent vasoconstrictor frequent with IV use. > Teach client to report
intervals of 2-4 contractions), congestion and action. I.V. use may induce difficulty breathing,
hours nausea and vomiting diaphoresis sudden hypertension and headache, numb or cold
have occurred cerebrovascular accidents. extremities, severe
occasionally. As a last resort, give I.V. abdominal cramping
DRUG CLASSIFICATION MECHANISM PREGNANCY EFFECT ON EFFECT ON slowly over several minutes
OF ACTION RISK CATEGORY PREGNANCY LACTATION and monitor blood pressure
PC: Ergot Alkaloid and Derivative Stimulates uterine Category C: Animal Use of Methergine is Mothers should not closely.
TC: oxytocic, lactation stimulant smooth muscles, reproductive studies contraindicated breast-feed during
producing have not been during pregnancy treatment with
sustained conducted with because of its Methergine and at
contractions and Methergine. It is also uterotonic effects. least 12 hours after
thereby shortens not known whether administration of the
the third stage of methylergonovine last dose. Milk
labor maleate can cause secreted during this
fetal harm or can period should be
affect reproductive discarded.
capacity.
Comment/ Remarks:
_____________________________________________________________________________________________________________________________________________________________
NAME of STUDENT: Marge Ysabelle T. De Guzman RATING:__________________ NAME of CI: Rogelio Villena
(075) 568-2475 loc. 8110, Fax: (075) 600-1468
School of Midwifery
Established in 1973

ROUTE/ USES EFFECTS
Brand name, Local Market Price) PRE- INTRA- POST-
ADMINISTRATION ADMINISTRATION ADMINISTRATION
Generic Name: Oxytocin I.V.: 10-40 units Induction of labor at Nausea or vomiting, cardiac arrhythmias, > Monitor and record >Monitor BP during > Be alert for adverse
by I.V. infusion in term; control of memory problems or PVCs, hypertension, uterine contractions, heart administration reaction
Brand Name: Pitocin 1000 mL of postpartum bleeding; confusion, runny subarachnoid rate, BP, intrauterine >If contractions are less than 2 >Monitor I/O. Antidiuretic
intravenous fluid adjunctive therapy in nose, sore throat, or hemorrhage pressure, fetal heart rate, minutes apart, if they’re above effect may lead to fluid
at a rate sufficient management of coughing, severe Fetal effects: fetal and blood loss q15. 50mm Hg, or if they last overload, seizures, and coma
Local Market Price: to control uterine abortion headaches, bradycardia, 90seconds or longer, stop > Regulate rate of oxytocin
atony hallucinations, neonatal jaundice, >never give oxytocin infusion, and turn patient on delivery; monitor rate and
vomiting, confusion, low Apgar scores simultaneously by more her side, and notify prescriber strength of contractions
seizures and severe nauseas, vomiting, than one route. >Ensure fetal position and
hypertension and postpartum size and absence of
irregular heartbeats. hemorrhage, uterine complications that are
rupture, pelvic contraindicated with
hematoma, uterine oxytocin therapy
hypertonicity, spasm > Ensure continuous
DRUG CLASSIFICATION MECHANISM PREGNANCY EFFECT ON EFFECT ON observation for induction of
OF ACTION RISK CATEGORY PREGNANCY LACTATION labor; fetal monitoring is
PC: Exogenous Agent TC: oxytocic, Causes potent and Oxytocin has been Oxytocin is It has been used in preferred.
lactation stimulant selective assigned to a indicated during mothers having
stimulation of pregnancy category X pregnancy to induce difficulty with
uterine and by the FDA. There are labor; it precipitates engorgement and
mammary gland no known indications uterine contractions breast-feeding.
smooth muscles, for use in the first and abortion. Because several
producing trimester of small studies have
sustained pregnancy other than failed to show a
contractions, in relation to beneficial effect,
induces labor and spontaneous or oxytocin is not used
milk ejection and induced abortion. It for this indication.
reduces would not be Oxytocin is excreted
postpartum expected to present a in the breast-milk,
bleeding risk of fetal but is not expected to
abnormalities. have adverse effects
in the infant.
(075) 568-2475 loc. 8110, Fax: (075) 600-1468
School of Midwifery
Established in 1973

ROUTE/ USES EFFECTS
Brand name, Local Market PRE- INTRA- POST-
Price) ADMINISTRATION ADMINISTRATION ADMINISTRATION
Generic Name: Lozartan The usual starting dose is Treatment of upper respiratory Headache, >Assess patient’s health > Monitor patient’s intake > Be alert for adverse
Potassium 50 mg, but people treated hypertension, alone infection, dizziness, dizziness, syncope, history. and output. reaction.
with diuretics may be or in combination stuffy nose, back insomnia, >Assess patient’s blood > Administer drug at daytime. > Monitor patient’s sleeping
Brand Name: started off with 25 mg, with other pain hypotension, rash, pressure. pattern.
Cozaar once or twice daily. antihypertensive urticaria, pruritus, > Assess patient’s renal
For pediatric Agents. alopecia, dry skin, function
Local Market Price: hypertensive patients Treatment of diabetic diarrhea, abdominal
older than 6, the neuropathy with an pain, nausea,
recommended starting elevated serum constipation, dry
dose is 0.7 mg, once creatinine and mouth, URI
daily, up to 50 mg. proteinuria in patients symptoms, cough,
with type 2 (non– sinus disorders,
insulin-dependent) back pain, fever,
diabetes and a history gout, muscle
of hypertension weakness
DRUG CLASSIFICATION MECHANISM OF PREGNANCY EFFECT ON EFFECT ON
ACTION RISK CATEGORY PREGNANCY LACTATION
cardiovascular Selectively blocks the Pregnancy [category Losartan can harm Unknown.
agent; angiotensin binding of angiotensin II C (first trimester), your unborn baby
II receptor antagonist; to specific tissue category D (second causing injury and
antihypertensive receptors found in the and third trimesters)] even death. Stop
vascular smooth muscle taking losartan if
and adrenal gland; this you become
action blocks the pregnant and call
vasoconstriction effect of your doctor right
the renin-angiotensin away.
system as well as the
release of aldosterone
leading to decreased
blood pressure.
(075) 568-2475 loc. 8110, Fax: (075) 600-1468
School of Midwifery
Established in 1973

ROUTE/ USES EFFECTS
Brand name, Local Market PRE- INTRA- POST-
Price) ADMINISTRATION ADMINISTRATION ADMINISTRATION
Generic Name: Omeprazole 10mg to 20mg a day for Gastric acid-pump Abdominal pain, Diarrhea, nausea, >Take the drug before >Evaluate fluid and intake >Have regular medical
indigestion inhibitor: Suppresses constipation, fatigue, meals. > Watch for elevated liver follow-up visits.
Brand Name: Losec (CAN) 20mg to 40mg a day for gastric acid secretion diarrhea, flatulence, constipation, >Assess Vital Signs function test results >Caution patient to avoid
acid reflux by specific inhibition gastrointestinal vomiting, flatulence, > Check for abdominal driving and other hazardous
20mg to 40mg a day for of the hydrogen- disturbances, acid regurgitation, Pain, emesis, Diarrhea or >Instruct patient to activities until he know drug
Local Market Price: stomach ulcers potassium ATPase headache, nausea, taste perversion, constipation. swallow capsules or tablets effects concentration and
20mg to 120mg a day for enzyme system at the vomiting arthralgia, myalgia, >Tell patient to take 30-60 whole and no to chew or alertness
Zollinger-Ellison secretory surface of urticaria, dry mouth, minutes before a meal, crash them.
syndrome, a condition the gastric parietal dizziness, headache, preferably in morning.
where the body produces cells; blocks the final paranesthesia,
a lot more stomach acid step of acid abdominal pain,
than is needed. production. skin rashes,
weakness, back
pain, upper
respiratory
infection, cough.
DRUG CLASSIFICATION MECHANISM OF PREGNANCY EFFECT ON EFFECT ON
ACTION RISK CATEGORY PREGNANCY LACTATION
Antisecretory drug Gastric acid-pump Epidemiologic In most cases, In most cases,
Proton pump inhibitor inhibitor: Suppresses studies have omeprazole is safe omeprazole is safe
gastric acid secretion by demonstrated that to take during to take during
specific inhibition of the major malformities pregnancy or while pregnancy or while
hydrogen-potassium risks with use in breastfeeding. breastfeeding.
ATPase enzyme system pregnant patients are When you’re
at the secretory surface unlikely. pregnant, it’s better
of the gastric parietal to treat indigestion
cells; blocks the final without taking a
step of acid production. medicine.
(075) 568-2475 loc. 8110, Fax: (075) 600-1468
School of Midwifery
Established in 1973
DRUG NAME DOSAGE/ INDICATIONS SIDE ADVERSE MIDWIFE’S RESPONSIBILITY

ROUTE/ / EFFECTS EFFECTS
(Generic Name/ FREQUENCY USES
Brand name, Local PRE- INTRA- POST-
Market Price) ADMINISTRATION ADMINISTRATION ADMINISTRATION
Generic Name: Hyoscine Oral Buscopan Dry mouth, dizziness, anaphylactic >Assess for eye pain > Encourage patient to void. > Monitor urine output
Butylbromide Adult: 30 mg / day in 3 Tablets are constipation, reactions, anaphylactic shock, >Assess for urinary Monitor BP for possible >Be alert for adverse
divided doses if needed dose indicated for the blurred vision, disorientation, hesitancy hypertension. reactions and drug
Brand Name: Buscopan can be increased to 80 mg / relief of spasm decreased restlessness, irritability, >Assess for constipation. >For pregnant women, interactions.
day in 4 divided doses. of the genito- sweating, drowsiness, confusion, >Avoid strict heat monitor cervical effacement > Overdose may cause
Injection: 20 mg IV/IM if urinary tract or urinary hallucination, delirium, impaired >Raise side rails as a and dilatation. curare-like effects, such as
Local Market Price: needed same dose can be gastrointestinal hesitancy, urine memory, hypotension, precaution because some >Drug compatibility should respiratory paralysis. Keep
repeated. tract and for the retention, tachycardia, palpitations, patients become be monitored closely in emergency equipment
Maximum dose: 100 mg / day symptomatic tachycardia, flushing, dry mouth, temporarily excited or patients requiring adjunctive available.
Children: 30 mg / day in 3 relief of Irritable drowsiness constipation, nausea, epigastric disoriented and some therapy > Avoid driving & operating
divided doses Bowel distress, flushing, urinary develop amnesia or become machinery after parenteral
Infants: 15 mg / day in 3 Syndrome retention, dyspnea, bronchial drowsy. administration.
divided doses plugging, depressed respiration,
mydriasis, dilated pupils,
difficulty of swallowing.
DRUG MECHANISM OF PREGNANCY EFFECT ON EFFECT ON LACTATION
CLASSIFICATION ACTION RISK PREGNANCY
CATEGORY
Antispasmodic; Buscopan does not readily Category C: There are limited There is insufficient information
Anticholinergic pass the blood-brain barrier. Either studies in data from the use on the excretion of hyoscine
It’s a competitive antagonist animals have of hyoscine butylbromide and its metabolites
of the actions of revealed adverse butylbromide in in human milk. A risk to the
acetylcholine and other effects on the pregnant breastfeeding child cannot be
muscarinic agonists. The fetus and there women. As a excluded. Use of Buscopan
receptors affected are those of are no controlled precautionary during breastfeeding is not
peripheral structures that are studies in measure It is not recommended
either stimulated or inhibited women or recommended
by muscarine, ie. smooth and animals are not during
cardiac muscle available. pregnancy.
(075) 568-2475 loc. 8110, Fax: (075) 600-1468
School of Midwifery
Established in 1973

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Urdaneta City University

1 San Vicente West, Urdaneta City, Pangasinan 2428

MIDWIFERY PHARMACOLOGIC NOTES

MIDWIFERY PHARMACOLOGIC NOTES

MIDWIFERY PHARMACOLOGIC NOTES

DRUG NAME DOSAGE/ INDICATIONS/ SIDE EFFECTS ADVERSE MIDWIFE’S RESPONSIBILITY

MIDWIFERY PHARMACOLOGIC NOTES

DRUG NAME DOSAGE/ INDICATIONS/ SIDE EFFECTS ADVERSE MIDWIFE’S RESPONSIBILITY

MIDWIFERY PHARMACOLOGIC NOTES

DRUG NAME DOSAGE/ INDICATIONS SIDE ADVERSE MIDWIFE’S RESPONSIBILITY

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