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Acute Lymphoblastic Leukemia Treatment Regimens PDF
Acute Lymphoblastic Leukemia Treatment Regimens PDF
References
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>0.1μmol/L at 48 hrs after MTX infusion ends.
1. NCCN Clinical Practice Guidelines in Oncology™. Acute Lympho- 6. Vignetti M, Fazi P, Cimino G, et al. Imatinib plus steroids
blastic Leukemia. v 1.2012. Available at: http://www.nccn.org/ induces complete remissions and prolonged survival in elderly
professionals/physician_gls/pdf/all.pdf. Accessed June 21, 2012. Philadelphia chromosome-positive patients with acute lympho-
2. Schultz KR, Bowman WP, Aledo A, et al. Improved early event- blastic leukemia without additional chemotherapy: results
free survival with imatinib in Philadelphia chromosome-positive of the Gruppo Italiano Malattie Ematologiche dell’Adulto
acute lymphoblastic leukemia; a Children’s Oncology Group (GIMEMA) LAL0201-B protocol. Blood. 2007;109:3676–3678.
study. J Clin Oncol. 2009;27:5175-5181. 7. Foá R, Vitale A, Vignetti M, et al. Dasatinib as first-line treat-
3. Ravandi F, O’Brien S, Thomas D, et al. First report of phase 2 ment for adult patients with Philadelphia chromosome-positive
study of dasatinib with hyper-CVAD for the frontline treatment acute lymphoblastic leukemia. Blood. 2011;118:6251–6258.
of patients with Philadelpia chromosome-positive (Ph+) acute 8. Huguet F, Leguay T, Raffoux E, et al. Pediatric-inspired therapy
lymphoblastic leukemia. Blood. 2010;116:2070–2077. in adults with Philadelphia chromosome-negative acute
4. Thomas DA, Farderl S, Cortes J, et al. Treatment of Philadelphia lymphoblastic leukemia: the GRAALL-2003 study. J Clin Oncol.
chromosome-positive acute lymphocytic leukemia with hyper- 2009;27:911–918.
CVAD and imatinib mesylate. Blood. 2004:103:4396–4407. 9. Kantarjian H, Thomas D, O’Brien S, et al. Long-term follow-up
5. Yanada M, Takeuchi J, Sugiura I, et al. High complete remission results of hyperfractionated cyclophosphamide, vincristine,
rate and promising outcome by combination of imatinib and doxorubicin, and dexamethasone (Hyper-CVAD), a dose-
chemotherapy for newly diagnosed BCR-ABL-positive acute intensive regimen, in adult acute lymphocytic leukemia.
lymphoblastic leukemia: a phase II study by the Japan Adult Cancer. 2004;101:2788–2801.
Leukemia Study Group. J Clin Oncol. 2006;24:460–466.
(Created 07/2012)
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