PT (Prothrombin time) PTT (Partial prothrombin time) BT (bleeding time)

Measured by: Take patient’s plasma Take patient’s plasma and add Make a standardized
and add tissue factor material that activates the cut on patients arm
>> measure how long contact activation pathway and measure how
the clot is formed (eg. Silica) >> measure how long the bleeding
long the clot is formed stops
N value 10-13s; 25-40s; 2-9 minutes
-Always reported with -you also have to add
PT is always reported phospholipid that normally
with INR because of combines with tissue factor to
variability in labs; form thromboplastin (but here
1 = N; >1 = blood is we are not adding the whole
taking longer to clot thing, we don’t add
thromboplastin) so this is
partial thromboplastin

What does it test? Tests how effectively Tests function of: Platelet function
tissue factor activates: 1. Contact activation (disorders of
1. Tissue factor pathway coagulation cascade
pathway 2. Final common should not affect
2. Final common pathway bleeding time)
pathway
Factors tested: 10, 7, 5, 2 12, 11, 9, 8, 10, 5, 2
(prothrombin) (prothrombin)