This document summarizes various agents that can be used to treat hyperkalemia in an emergency department setting. It lists the agent, dose, onset time, duration of effect, and potential complications for membrane stabilization agents like calcium gluconate and sodium chloride, redistribution agents like insulin and albuterol, and elimination agents such as loop diuretics, sodium bicarbonate, sodium polystyrene sulfonate, and hemodialysis.
This document summarizes various agents that can be used to treat hyperkalemia in an emergency department setting. It lists the agent, dose, onset time, duration of effect, and potential complications for membrane stabilization agents like calcium gluconate and sodium chloride, redistribution agents like insulin and albuterol, and elimination agents such as loop diuretics, sodium bicarbonate, sodium polystyrene sulfonate, and hemodialysis.
This document summarizes various agents that can be used to treat hyperkalemia in an emergency department setting. It lists the agent, dose, onset time, duration of effect, and potential complications for membrane stabilization agents like calcium gluconate and sodium chloride, redistribution agents like insulin and albuterol, and elimination agents such as loop diuretics, sodium bicarbonate, sodium polystyrene sulfonate, and hemodialysis.
Agent Dose Onset Duration Complications Membrane Stabilization Calcium 10 mL IV over Immediate 30-60 min Hypercalcemia gluconate (10%) 10 min Hypertonic 50 mL IV push Immediate Unknown Volume (3%) sodium overload chloride Hypertonicity Redistribution Insulin (short 10 units IV 20 min 4-6 hr Hypoglycemia acting) push, with 25-40 g dextrose (50% solution) Albuterol 20 mg in 4 mL 30 min 2 hr Tachycardia normal saline solution, nebulized over 10 min Inconsistent response Elimination Loop diuretics Furosemide 40-80 mg IV 15 min 2-3 hr Volume depletion Bumetanide 2-4 mg IV Sodium 150 mmol/L IV One Hr According to Metabolic bicarbonate at variable rate Duration of alkalosis infusion Volume overload Sodium 15-30 g in 15-30>2 hr 4-6 hr Variable effect polystyrene mL (70% sulfonate (SPS, sorbitol orally) Kayexalate, Kionex) Intestinal necrosis Hemodialysis Immediate 3 hr Arrhythmias