Pathways in Human Cancer

Direct stimulatory modification Tentative stimulatory modification TYPES OF GENETIC ALTERATIONS: TYPES OF CONFERRED CAPABILITIES:
Ras Common protein name oncogene mut Type of genetic alteration
mut Direct inhibitory modification Transcriptional contribution mut Point mutation trans Translocation vir Viral infection Evading apoptosis Insensitivity to Limitless replicative
Ras Structural representative tumor Type of conferred anti-growth signals potential
from PDB suppressor capability Multistep stimulatory amp Amplification del Deletion exp Increased expression Self-sufficiency in Tissue invasion Sustained angiogenesis
modification (unknown mechanism) growth signals & metastasis

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