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2.1 Microsensors
Definition of Sensor:
A sensor is a device that converts one form of energy into another and provides
the user with a usable output in response to a specific measurable input.
Basic idea:
- To fabricate a sensor in which acoustic waves are propagated, and where
some aspect of that propagation (e.g., velocity, amplitude, etc.) is changed by
the adsorption/reaction or viscosity of the sensed species. (Kovacs, 2000)
- Generation of acoustic waves: piezoelectric (the most popular),
magnetostrictive, etc.
Biomedical Sensors:
To detect biological substance.
Example: one for glucose (血糖) concentration
- Glucose + O2 → gluconolactone + H2O2
- Then, H2O2 → O2 + 2H+ + 2e-
- By measuring the current or the pH, the glucose concentration can be
determined.
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表一 二十位糖尿病專家對糖尿病診斷之分歧標準
(http://www.ilshb.gov.tw/dm/)
Biosensors
Definition: Any measuring devices that contain a biological element.
The biomolecules (such as enzymes, antibodies, etc.), when attached to
the sensing elements, can alter the output signals of the sensors.
Schematic of biosensors:
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Biotesting and Analytical Systems
These systems separate various species in biological samples.
Electrohydrodynamics involves the driving of an ionized fluid by the
application of electric fields.
4 types:
I. Chemiresistor sensors
- Chemiresistros are simply structures in which the resistance (or impedance)
between two electrical contacts is modified depending on the quantity of an
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unknown in the environment. (Kovacs, 2000)
- Example: A polymer called phthalocyanine is used with copper to sense NH 3
and NO2.
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after absorbing certain gases.
Catalyst deposition can speed up the reaction and hence increase the
sensitivity of the sensor.
Figure 2.6(b):
A special material changes its electric resistance when exposed to light.
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from these devices.
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- Mechanically induced diaphragm deformation and stresses are then
converted into electrical signal output through several means of transduction.
In Fig. 2.8, four piezoresistors implanted beneath the silicon die, and
a Wheatstone bridge circuit is used.
- By an applied pressure, the values of R1 and R3 increase, whereas those of R2
and R4 decrease.
- The output voltage from the Wheatstone bridge is:
R1 R2
Vo Vin [eq. 2.1]
R1 R4 R2 R3
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R2 (-v)
R3 (+v)
- Capacitance:
A
C r 0 [Eq. 2.2]
d
where εr: relative permittivity, ε0: permittivity of vacuum, d: gap, and A:
area.
- Output Voltage:
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C
Vo Vin [eq. 2.3]
2( 2C C )
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- Disadvantages:
Not as sensitive as those with piezoresistors.
The relation between the output and the capacitance change is
nonlinear.
Thermocouples:
- A voltage is produced at the open ends of two dissimilar metallic wires when
the junction of the wires is heated (Fig. 2.13a).
- Seebeck effect:
A thermocouple is arranged with both hot and cold junctions (Fig.
2.13b), and the following voltage is generated:
V=βΔT
where β is the Seebeck coefficient, and ΔT is the temperature
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difference between hot and cold junctions.
Microthermopile:
- Thermopiles operate with both hot and cold junctions, but they are arranged
with thermocouples in parallel and voltage output in series (Fig. 2.14).
V=NβΔT
where N is the number of thermocouple pairs.
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In Fig. 2.15, a total of 32 polysilicon-gold thermocouples were used
in the thermopile.
- The chip dimension: 3.6mm X 3.6mm X 20μm
- A typical output signal of 100 mV was obtained from a 500 K blackbody
radiation source of Q=0.29 mW/cm2.
2.2 Microactuation
Four commonly used means for microdevice actuation are:
(1) thermal forces;
(2) shape memory alloys;
(3) piezoelectric crystals;
(4) electrostatic forces.
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2.2.2 Actuation Using Shape Memory Alloys
Principles:
- The shape memory alloys (SMA) tend to return to their original shape at
a preset temperature.
- Example in Fig. 2.17,
A SMA strip is in a bent shape at a designed preset temperature T.
The silicon beam is set straight at the room temperature.
Heating the SMA to temperature T would prompt the SMA strip to
return to its original bent shape, causing the beam to deform with
the strip.
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- Example:
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Electrostatic Force in Parallel Plates
- In Fig. 2.21, the induced capacitance between the plates is
A WL
C r 0 r 0 [Eq. 2.6]
d d
- The energy associated with the electric potential can be expressed as:
1 WLV 2
U CV 2 r 0 [Eq. 2.7]
2 2d
- The associated force that is normal to the plates is
U 1 WLV 2
Fd r 0 2 [Eq. 2.8]
d 2 d
- The associated forces in the W and L directions are
U 1 r 0 LV 2
FW [Eq. 2.10]
W 2 d
U 1 r 0WV 2
FL [Eq. 2.11]
L 2 d
- Drawback:
The force magnitude is low.
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2.3 MEMS with Microactuators
2.3.1 Microgrippers
Principle:
The required gripping forces in a gripper can be provided either by normal
force (Fig. 2.24a) or by the in-plane forces from pairs of misaligned plates (Fig.
2.24b).
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Disadvantage of the design in Fig. 2.24a:
The electrodes occupy excessive space.
2.3.2 Micromotors
Two types: linear and rotary motors
- Linear motors:
Energizing the pair of electrodes A and A’ causes the top plate to
move to the left until they are fully aligned.
Then, energize the pairs of electrodes B and B’, C and C’, and D
and D’ in sequence.
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- Rotary motors:
2.3.3 Microvalves
Applications:
- Precision control of gas flow for manufacturing processes;
- Biomedical systems such as in controlling the blood flow in an artery
(動脈).
The microvalve in Fig. 2.29 (Jerman, 1991) uses the thermal bimorph
actuation (like the one in Fig. 2.16).
- Heating the two electrical resistor rings can cause a downward
movement of the diaphragm to close the flow passage.
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Figure 2.30,
- The downward bending of the silicon diaphragm (to close the valve) is
activated by heat supplied to a special liquid in the sealed compartment
(隔間) above the diaphragm.
2.3.4 Micropumps
Figure 2.31,
- Use the electrostatic actuation to deform the diaphragm.
- Apply a voltage across the electrodes
Diaphragm: deform upward
Chamber volume: increase
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Chamber pressure: reduce
Inlet check valve: open (fluid flows in)
Then, cut off the applied voltage
Diaphragm: return to its initial position
Chamber volume: reduce
Chamber pressure: increase
outlet check valve: open (fluid flows out)
- Zengerle (1992) reported
Diaphragm size: 4mm×4mm×25μm thick
Gap between the diaphragm and electrode: 4μm
Actuation frequency: 1 to 100 Hz
Pumping rate: 70μL/min at 25 Hz
2.4 Microaccelerometers
Functions:
- measure accelerometer;
- measure the applied force by F=ma.
Applications:
- ±2g range for the car’s suspension system and antilock braking system.
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- ±50g range for the actuation of air bags.
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鏈] made of elastic material), and a differential capacitive sensing.
- Principles:
In the event of acceleration, the proof mass will displace in the
direction opposite to the acceleration. (??)
The differential capacitive sensor cell senses the movement.
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2.5 Microfluidics
Applications:
- Chemical analysis
- Biological and chemical sensing
- Drug delivery
- Molecular separation such as DNA analysis
- Amplification, sequencing or synthesis of nucleic acids
- Environmental monitoring
Principal advantages:
- Small samples
- Better performance with reduced power consumption
- Can be combined with traditional electronic systems for a lab-on-a-chip
(LOC)
- Produced in batches s.t. disposable (可丟棄的)
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