GENERIC BRAND DRUG CLASS DOSAGE AND HOW MECHANISM OF INDICATION CONTRAINDI SIDE - NURSING

NAME NAME FREQUENCY SUPPLIED ACTION CATION EFFECTS RESPONSIBILITIES

celecoxib Celebrex Pharmacologic 400 mg OD Capsules Exhibits anti- Adjunctive ● CNS: Before:
class: p.r.n inflammatory, treatment to Hypersensiti dizziness, - Assess pt’s
Nonsteroidal analgesic, decrease vity to drug, drowsines history of allergic
cyclooxygenase- and antipyretic the number sulfonamide s, reaction to the
2 (COX-2 ) action due to of s, headache, drug
inhibitor, inhibition adenomatous or other insomnia, - Monitor complete
anti- of the enzyme colorectal NSAIDs fatigue blood count,
CV: electrolyte
inflammatory COX-2 polyps in ● Severe
peripheral levels, creatinine
drug (NSAID) familial hepatic clearance, and
Therapeutic adenomatous impairment edema
occult fecal blood test
class: polyposis ● History of EENT:
and liver function
ophthalmi
Antirheumatic asthma or test results every 6
c effects, to 12 months
Pregnancy risk urticaria
tinnitus,
category C ● Advanced
pharyngiti During:
renal
s, rhinitis, - Instruct patient to
disease
sinusitis take drug with
● Late GI: food or milk.
pregnancy nausea, - Teach patient to
● diarrhea, avoid aspirin and
Breastfeedi constipati other NSAIDs (such as
ng ibuprofen and
on,
naproxen) during
abdominal therapy.
pain,
dyspepsia,
After:
flatulence, - Advise patient to
dry immediately report
mouth, GI bloody stools, blood in
bleeding vomit, or
GU: signs or symptoms of
menorrha liver damage
gia (nausea, fatigue,
Hematolo lethargy, pruritus,
gic: yellowing
decreased of eyes or skin,
hemoglobi tenderness on
upper right side of
n
abdomen, or flulike
or symptoms).
hematocri
t,
eosinophili
a,
 epistaxis,
bruising,

SOURCE: NURSE’S DRUG GUDE 2008, SPRINGHOUSE