Which of the following statement are true regarding cephalosporin?

A. it�s a 4th generation

B. once daily dose sufficient
C. it�s a prodrug
D. all of this
ANSWER: A

Which reaction is is catalyzed by beta lactamase enzyme for crosslinking the

bacteria cell wall?
A. the final crosslinking reaction to form the bacterial cell wall
B. the hydrolysis of the acyl side chain from penicillin structure
C. the hydrolysis of the 4 member ring present in penicillin
D. the biosynthesis of the penicillin structure from the amino acids valine and
cystein
ANSWER: C

The antimicrobial activity of penicillin is due to?

A. thiazolidine ring
B. beta lactam ring
C. 6 amino penicillinic acid
D. none of these.
ANSWER: C

Mechanism of action of cephalosporins involves?

A. inhibition of Beta lactamase
B. inhibition of peptide synthesis
C. inhibition of Trans peptide enzyme
D. all of these
ANSWER: B

Which is not semi synthetic penicillin?

A. penicillin
B. penicillin G
C. amoxicillin
D. none of these.
ANSWER: B

Select the fourth generation of cephalosporin

A. cefpirom
B. cefuroxime
C. See both a and b
D. none of these.
ANSWER: A

Drug which interface with the bacterial cell wall synthesis is?
A. chloramphenicol
B. tetracycline
C. penicillin and cephalosporin
D. all of these
ANSWER: C

What crucial feature of a penicillin is involved in in its mechanism of action?

A. carboxylic acid
B. beta lactam ring
C. Aisa sidechain
D. thiazolidine ring
ANSWER: C

One of the following is not penicillin susceptible?

A. penicillin G
B. amoxicillin
C. cloxacillin
D. all of the above
ANSWER: B

Most effective antibiotic for acne?

A. gentamycin
B. bacitracin
C. sulphadiazine
D. Minocycline
ANSWER: D

Tetracycline are derivatives of

A. Octa hydro naphthacene
B. Hepta hydro naphthacene
C. Octa methoxy naphthacene
D. all of the above
ANSWER: A

Tetracycline is used for?

A. cholera
B. meningitis
C. both a and b
D. none of these.
ANSWER: A

Grey baby syndrome is caused by?

A. chloramphenicol
B. gentamycin
C. both a and b
D. none of these
ANSWER: A

Broad spectrum antibiotic is?

A. tetracycline
B. streptomycin
C. Paracetamol
D. all of the above
ANSWER: B

Which of the following statement about tetracycline is false?

A. they are autogenic
B. they cause photosensitivity
C. enhanced absorption if taken with food
D. they can inhibit metal protein
ANSWER: C

Tetracycline should not be taken with?

A. milk
B. iron
C. magnesium
D. all of the above
ANSWER: D

Tetracycline inhibit Protein synthesis by

A. inhibiting initiation and causing MS railing of m m r n a
B. binding to 30 s subunit and binding off amino acylt RNA
C. inhibiting peptidyl transferase activity
D. inhibiting translocation
ANSWER: B

Which of these antibiotics are safe in Renal failure?

A. tetracycline
B. gentamycin
C. both a and b
D. none of the above.
ANSWER: A

Tetracycline is?
A. Narrow spectrum
B. obtained from soil actinomycetes
C. it has chelating properties
D. B and C are correct
ANSWER: D

Which of the following is high ceiling diuretics?

A. Furesemide
B. acetazolamide
C. thiazide
D. all of the above
ANSWER: A

Loop diuretics by?

A. inhibition of NaCl symport
B. inhibition of Na+,K+ and Cl- Co transpor
C. inhibition of Na+ and K+ATPase
D. none of the above
ANSWER: B

Which one of the following drug can increased the concentration of Na and Cl in
urine?
A. furosemide
B. acetazolamide
C. Ethacrynic acid
D. none of the above
ANSWER: C

Which one of the Following is true about Furesemide?

A. it is given only by oral
B. it courses mild diuresis
C. it is used in in pulmonary edema
D. act on PCT
ANSWER: C

Which class of diuretics work by acting on the proximal tubel?

A. carbonic anhydrous inhibitors
B. loop diuretics
C. potassium spearing channels
D. thiazide diuretics
ANSWER: C

Potassium supplements are given with?

A. thiazide
B. tetracycline
C. Paracetamol
D. none of the above
ANSWER: A