ANTIBIOTIC REVISION

1. Which is none antibiotics?

a. Streptomycin
b. Penicillin
c. Co-trimoxazole
d. Chloramphenicol
2. Bactericidal effect is:
a. Inhibition of bacterial cell division
b. Inhibition of young bacterial cell growth
c. Destroying (Killing) of bacterial cells
d. Formation of bacterial L-form
3. Which of the following is a bactericidal effect?
a. Tetracyclines
b. Macrolides
c. Penicillin's
d. Chloramphenicol
4. Bacteriostatic effect is:
a. Inhibition of bacterial cell division
b. Inhibition of young bacterial cells growth
c. Destroying of bacterial cells
d. Formation of bacterial L-form
5. Which one is a bacteriostatic effect:
a. Carbapenems
b. Macrolides
c. Aminoglycosides
d. Cephalosporins
6. Which of the following antibiotics related toa beta-lactam ring?
a. Penicillin's
b. Cephalosporins
c. Carbapenems and monobactams
d. All groups
7. Which one drug belonging to antibiotics-macrolides:
a. Neomycin
b. Doxycycline
c. Erythromycin
d. Cefotaxime
8. Which one drug belonging to antibiotics-carbapenems:
a. Aztreonam
b. Amoxicillin
c. Imipenem
d. Clarithromycin

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ANTIBIOTIC REVISION

9. Which one drug belonging to antibiotics-monobactams:

a. Ampicillin
b. Bicillin-5
c. Aztreonam
d. Imipenem
10. Which one drug belongs to antibiotics-cephalosporins:
a. Streptomycin
b. Cefaclor
c. Phenoxymethylpenicillin
d. Erythromycin
11. Which one drug belonging to lincozamides:
a. Erythromycin
b. Lincomycin
c. Azithromycin
d. Aztreonam
12. Which one drug belonging to antibiotics-tetracyclines:
a. Doxycycline
b. Streptomycin
c. Clarithromycin
d. Amoxicillin
13. Which one is not Related to aminoglycosides antibiotics?
a. Gentamycin
b. Streptomycin
c. Clindamycin
d. Neomycin
14. Antibiotics inhibiting the bacterial cell wall synthesis are:
a. Cephalosprines
b. Tetracyclines
c. Aminoglycosides
d. Macrolides
15. Antibiotic inhibiting bacterial RNA synthesis is:
a. Erythromycin
b. Rifampin
c. Chloramphenicol
d. Imipenem
16. Antibiotics altering permeability of cell membranes are:
a. Erythromycin
b. Polymyxins
c. Tetracyclines
d. Cephalosporins

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17. Which one is not inhibit the protein synthesis in bacterial cells?
a. Macrolides
b. Aminoglycosides
c. Glycopeptides
d. Tetracyclines
18. Biosynthetic penicillins are effective against:
a. Gram +V and gram- -V cocci, Corynebacterium diphtheria,
spirochetes, Clostridium gangrene
b. Corynebacterium diphtheria, mycobacteria
c. Gram positive cocci, viruses
d. Gram negative cocci, Rickettsia, mycotic infections
19. Which of the following drugs is a gastric acid resistant?
a. Penicillin G
b. Penicillin V
c. Carbenicillin
d. Procaine penicillin
20. Which of the following drugs is penicillinase resistant?
a. Oxacillin
b. Amoxicillin
c. Bicillin-5
d. Penicillin G
21. Which one of the following drugs not have a prolonged effect?
a. Penicillin G
b. Procaine penicillin
c. Benzathathine penicillin
d. Ampicillin
22. Mechanism of penicillin's antibacterial effect is:
a. Inhibition the synthesis of bacterial cell wall
b. Inhibition of beta-lactamase in the bacterial cell
c. Activation of endogenous proteases, that destroy bacterial cell wall
d. Alteration of cell membrane permeability
23. Which one beta-lactamase inhibitor for co-administration with
penicillin:
a. Clavulanic acid
b. Sulbactam
c. Tazobactam
d. All of the above
24. Cephalosporines are drugs of choice for treatment of:
a. Gram-positive microorganism infections
b. Gram-negative microorganism infections
c. Gram-negative and gram-positive infections.
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d. Only bacteroid infections

25. Carbapenems are effective against:
a. Gram-positive microorganisms
b. Gram-negative microorganisms
c. Only bacteroid infections
d. Broad-spectrum
26. Which one of the following antibiotics are not macrolides?
a. Erythromycin
b. Clarithromycin
c. Lincomycin
d. Roxithromycin
27. Tetracyclines have following side effects:
a. Irritation of gastrointestinal mucosa, phototoxicity
b. Hepatotoxicity, anti-anabolic effect
c. Dental hypoplasia, bone deformities
d. All of the above
28. Which one drug belonging to antibiotics-aminoglycosides?
a. Erythromycin
b. Gentamycin
c. Vancomycin
d. Polymyxin
29. Aminoglycosides are effective against:
a. Gram positive organisms, anaerobic microorganisms, spirochetes
b. Broad-spectrum, except Pseudomonas aeruginosa
c. Gram negative microorganisms, anaerobic microorganisms
d. Broad-spectrum, except anaerobic organisms and viruses
30. Aminoglycosides have the following side effects:
a. Pancytopenia
b. Hepatotoxicity
c. Ototoxicity, nephrotoxicity
d. Irritation of gastrointestinal mucosa
31. Choose the characteristics of chloramphenicol:
a. Broad-spectrum. and a bactericidal effect.
b. Influences the Gram-+V organisms. and a bactericidal effect.
c. Influences the Gram -V organisms. and a bactericidal effect.
d. Broad-spectrum. Demonstrates a bacteriostatic effect.
32. Chloramphenicol has the following side effects:
a. Nephrotoxicity
b. Bone marrow depression
c. Hepatotoxicity
d. Ototoxicity
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33. Choose the characteristics of lincozamides:

a. Broad-spectrum. Demonstrates a bactericidal effect.
b. Influence mainly the anaerobic organisms, Gram negative cocci.
c. Broad-spectrum. Demonstrates a bacteriostatic effect.
d. Influence mainly the anaerobic organisms, Gram +V cocci.
34. Lincozamides have the following side effects:
a. Nephrotoxicity
b. Carcinogenetic
c. Pseudomembranous colitis
d. Irritation of respiratory organs
35. Vancomycin has the following side effects:
a. Pseudomembranous colitis
b. Hepatotoxicity
c. “Red neck” syndrome, phlebitis (Red man syndrome)
d. All of the above
36. Sulfonamides are effective against:
a. Bacteria and Chlamydia
b. Actinomyces
c. Protozoa
b. All of the above
37. Combination of sulfonamides with trimethoprim:
a. Decreases the unwanted effects of sulfonamides
b. Increases the antimicrobial activity
c. Decreases the antimicrobial activity
d. Increases the elimination of sulfonamides
38. The measures for prevention of sulfonamide crystalluria are:
a. Taking of drinks with acid pH
b. Taking of drinks with alkaline pH
c. Taking of saline drinks
d. Restriction of drinking
39. Sulfonamides have the following side effects on blood system:
a. Hemolytic anemia
b. Thrombocytopenia
c. Granulocytopenia
d. All of the above
40. Mechanism of Trimethoprim’ action is:
a. Inhibition of cyclooxygenase
b. Inhibition of dihydropteroate reductase
c. Inhibition of dihydropteroate synthase
d. Inhibition of DNA gyrase

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41. Sulfonamides have the following side effects:

a. Hematopoietic disturbances
b. Crystalluria
c. Nausea, vomiting and diarrhea
d. All of the above
42. Mechanism of Cycloserine action is:
a. Inhibition of mycolic acids synthesis
b. Inhibition of RNA synthesis
c. Inhibition of cell wall synthesis
d. Inhibition of pyridoxalphosphate synthesis
43. Mechanism of Streptomycin action is:
a. Inhibition of cell wall synthesis
b. Inhibition of protein synthesis
c. Inhibition of RNA and DNA synthesis
d. Inhibition of cell membranes permeability
44. The drug of choice for syphilis treatment is:
a. Gentamycin
b. Penicillin
c. Chloramphenicol
d. Doxycycline.

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