MCQ ON ANTI HYPERTENSIVE DRUG

Question # 1 (Multiple Answer) Advantages of oral clonidine (Catapres) (preanesthetic

medication):

A) enhances intrathecal morphine plus tetracaine postoperative analgesia

B) decreases inhaled anesthetic requirement
C) decreases injected and esthetic requirement
D) reduces reflex tachycardia caused by direct laryngoscopy for tracheal
intubation
E) increases plasma catecholamines; helps to maintain BP

Question # 2 (Multiple Choice) Acts as a competitive antagonist in both alpha1 and beta1
adrenergic receptors; has intrinsic sympathomimetic effect at beta2 adrenergic receptors:

A) clonidine (Catapres)
B) metoprolol (Lopressor)
C) acebutolol (Sectral)
D) labetalol (Trandate, Normodyne)
E) atenolol (Tenormin)

Question # 3 (Multiple Choice) Vasodilator which produces methemoglobin in the body

A) hydralazine (Apresoline)
B) minoxidil (Loniten)
C) nitroprusside sodium (Nipride)

Question # 4 (Multiple Answer) Adverse effects associated with ACE inhibitors:

A) angioedema
B) dry cough
C) rhinorrhea
D) proteinuria

Question # 5 (Multiple Choice) Management of excessive hypotensive reaction probably

caused by continued ACE inhibitor treatment perioperatively:
 A) crystalloid fluid infusion
B) sympathomimetic administration
C) both
D) neither

Question # 6 (Multiple Answer) Side effects associated with clonidine use as analgesic:

A) respiratory depression
B) nausea
C) vomiting
D) delayed gastric emptying
E) none of the above

Question # 7 (Multiple Choice) Hydralazine (Apresoline) and minoxidil (Loniten),

administered as monotherapy, might be expected to produce:

A) water retention
B) cardiac stimulation (reflex-mediated)
C) both
D) neither

Question # 8 (Multiple Choice) Mechanism of antihypertensive action: clonidine

(Catapres) --

A) peripheral alpha1 adrenergic receptor blocker

B) peripheral beta2 adrenergic receptor agonist
C) central alpha2 adrenergic agonist
D) central beta-adrenergic agonist

Question # 9 (Multiple Choice) Antihypertensive drug: hypertrichosis

A) methyldopa (Aldomet)
B) clonidine (Catapres)
C) diltiazem (Cardiazem)
D) minoxidil (Loniten)
 E) propranolol (Inderal)

Question # 10 (Multiple Answer) Adverse effects of furosemide (Lasix):

A) gout
B) potassium depletion
C) ototoxicity