Anatomy and Physiology

For Phlebotomy

Unit 3
Principles of Medical technology
Practice
 Unit Outline
• Circulatory system review
• Preferred Puncture sites
• Structures punctured by the phlebotomy
needle.
• Vein vs Arteries vs Capillaries
• Blood
• Coagulation and Fibrinolysis
 Circulatory System
• Heart
• Blood vessels
– Arteries
– Capillaries
– Veins
• Blood
Preferred Puncture site

Antecubital fossa
 Structures punctured by
the phlebotomy needle
• Skin
• Hypodermis/Subcutaneous
• Blood Vessel
• Connective tissue
• Muscle
Structures punctured by
the phlebotomy needle
Structures punctured by
the phlebotomy needle
Structural characteristics of the
peripheral vascular system.

Citation: Overview of the Cardiovascular System, Mohrman DE, Heller L. Cardiovascular Physiology, 9e; 2018.
Available at: https://accessmedicine.mhmedical.com/content.aspx?bookid=2432&sectionid=190800340 Accessed:
January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
Vein vs Arteries vs Capillaries
Blood
 Formed elements

• Red cells - gas exchange: oxygen and carbon

• White cells
– Granulocytes—neutrophils, eosinophils, and
basophils
– Mononuclears – lymphocytes and monocytes
• Platelets - hemostasis
 Hemostasis
• Vascular spasm
• Platelet plug formation
• Coagulation – Fibrin formation
Citation: Overview of Hemostasis, Aster JC, Bunn H. Pathophysiology of Blood Disorders, 2e; 2016. Available at:
https://accessmedicine.mhmedical.com/content.aspx?bookid=1900&sectionid=137395249 Accessed: January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
 Coagulation and Fibrinolysis

• Thrombin
– converts Fibrinogen to Fibrin
– activates Plaminogen to Plasmin
Citation: Blood Disorders, Hammer GD, McPhee SJ. Pathophysiology of Disease: An Introduction to Clinical Medicine,
8e; 2019. Available at: https://accessmedicine.mhmedical.com/content.aspx?bookid=2468&sectionid=198220627
Accessed: January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
Citation: Bleeding and Thrombotic Disorders, Laposata M. Laboratory Medicine: The Diagnosis of Disease in the
Clinical Laboratory; 2014. Available at:
https://accessmedicine.mhmedical.com/content.aspx?bookid=1069&sectionid=60776603 Accessed: January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
Citation: Bleeding and Thrombotic Disorders, Laposata M. Laboratory Medicine: The Diagnosis of Disease in the Clinical
Laboratory; 2014. Available at: https://accessmedicine.mhmedical.com/content.aspx?bookid=1069&sectionid=60776603
Accessed: January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
Citation: Overview of Hemostasis, Aster JC, Bunn H. Pathophysiology of Blood Disorders, 2e; 2016. Available at:
https://accessmedicine.mhmedical.com/content.aspx?bookid=1900&sectionid=137395249 Accessed: January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
A classification of coagulation disorders.

Citation: Bleeding and Thrombotic Disorders, Laposata M. Laboratory Medicine: The Diagnosis of Disease in the Clinical Laboratory; 2014. Available at:
https://accessmedicine.mhmedical.com/content.aspx?bookid=1069&sectionid=60776603 Accessed: January 30, 2019
Copyright © 2019 McGraw-Hill Education. All rights reserved
THANK YOU!!