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SECTION 1 SPECIFICATIONS

1.1 OUTLINE ................................................................................................................................... 1


1.2 NAME AND MODEL .................................................................................................................. 1
1.2.1 Name................................................................................................................................... 1
1.2.2 Model................................................................................................................................... 1
1.3 CONFIGURATION AND DIMENSIONS..................................................................................... 1
1.3.1 Configuration ....................................................................................................................... 1
1.3.2 Power Supply ...................................................................................................................... 2
1.3.3 Dimensions and Weight ...................................................................................................... 2
1.3.4 Each Unit Function and Operation ...................................................................................... 2
1.4 PERFORMANCE, INTENDED USE AND EFFECTIVENESS ................................................... 4
1.4.1 Intended Use ....................................................................................................................... 4
1.4.2 Performance........................................................................................................................ 4
1.4.3 Functions............................................................................................................................. 7
1.5 ACOUSTIC NOISE LEVEL ...................................................................................................... 13
1.6 ENVIRONMENTAL CONDITIONS........................................................................................... 13
1.6.1 Operating Environment ..................................................................................................... 13
1.6.2 Power Source (Electric Ratings) ....................................................................................... 13
1.6.3 Reagent Recommendation................................................................................................ 14

CA-1500 S/M December 13, 2007


SECTION 1 SPECIFICATIONS
1.1 OUTLINE
The Sysmex CA-1500 Automated Blood Coagulation Analyzer obtains clotting times by detecting
changes in scattered light intensity reflected from a diluted sample with buffer, which is illuminated
by red light of LED.
Incubated plasma taken from the centrifuged sample blood is rapidly mixed with warmed reagent
and coagulation is performed and analyzed. Its result can be automatically displayed and printed.
The chromogenics substrate and Immunization Nephelometry as well as the biological activation
method are available on this unit. The optional CP (Cap Piercing) analysis is available.

1.2 NAME AND MODEL

1.2.1 Name
AUTOMATED BLOOD COAGULATION ANALYZER

1.2.2 Model
CA-1500

1.3 CONFIGURATION AND DIMENSIONS

1.3.1 Configuration
(1) Configuration
1) Main Unit
2) Pneumatic Unit (built-in type)
3) Sampler Unit (loading max. 5 racks (50 sample tubes))
(2) Options
1) Sample ID Bar Code Reader (built-in type)
Sample ID numbers can be automatically read by the bar code reader (BCR5342-TI), which
can scan the samples in one rack and the STAT sample.
2) Reagent ID Bar Code Reader (hand-held type)
Wand bar code reader can be connected to read the bar code attached on the reagent
container. This can also be used to register the sample ID of STAT samples.
3) Page Printer
Prints out analysis results. (BJ-410J or equivalent)
4) Laser Printer
Prints out analysis results. (LaserJet5L or equivalent)
5) Ticket Printer
Prints out analysis results. (DP-510 or equivalent)
6) Cap Piercing Unit (built-in type)

NOTE: The page printer and laser printer cannot be simultaneously connected.

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(3) Interface with Other Instruments
1) RS-232C
2) DPS or Host Computer can be connected.
3) HS can be connected.

1.3.2 Power Supply

(1) Input Voltage


100, 117, 220, 230, or 240 VAC ±10 %
(2) Frequency
50 Hz or 60 Hz
(3) Maximum Power Consumption
720 VA or less

1.3.3 Dimensions and Weight


(1) Dimensions
780 mm (width) x 500 mm (high) x 500 mm (depth) ± 3 % respectively
(excluding projections)
(2) Weight
Without CP Unit: 75 kg ± 10 % respectively (excluding sampler and optional units)
With CP Unit: 78 kg ± 10 % respectively (excluding sampler and optional units)

1.3.4 Each Unit Function and Operation

(1) Main Unit


1) Main Unit Power Switch
Turns the power ON/OFF.
2) Display Unit
Displays the analysis registrations, analysis results, stored information and operation
contents on the LCD.
3) Control Unit
Using LCD and Touch Panel controls the operation in dialog.
4) Transfer Unit
Transfers sample tubes.
5) Sample/Reagent arm Unit
Dispenses samples and reagents by the required volume.
6) Mechanical Stop Switch
Stops the operation temporary.
7) Detector Block
Determines the coagulation time by measuring changes in the intensity of light scattered by
increasing turbidity.
8) Chromogenic Unit
Detects the changes in the light absorbency by the transmitted light.
9) Temperature Control Unit
Controls temperatures for Detector Block, Reagent Heater Section and Cooling Section.
10) System Control Unit
Controls Main Unit system.

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11) Drive Circuit Unit
Controls each motor’s driving.
12) Pneumatic Unit
Supplies pressure and vacuum.
13) Sampler Unit
Enables the continuous automatic operations by the sampler. One sampler rack can contain
10 sample tubes. The rack can be shift separately and 5 samplers can be set
simultaneously.

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1.4 PERFORMANCE, INTENDED USE AND EFFECTIVENESS

1.4.1 Intended Use

This unit measures the coagulation of the plasma component of anti-coagulant (sodium citrate)
added human blood. Only FDP analysis include serum test.

1.4.2 Performance

(1) Measurement Parameters and Display Parameters (Unit is shown in [ ]).


1) Prothrombin Time (PT) [ second ]
Calculated Parameters:
Prothrombin Activation Percent [%]
Prothrombin Ratio [–]
INR (International Normalized Ratio) [–]
Derived Fbg (for overseas only) [ mg/dL ]
2) Activated Partial Thromboplastin Time (APTT) [ second ]
Calculated Parameters:
APTT Ratio (Selectable depending on the destination) [–]
Activation Percent (Selectable depending on the destination) [%]
3) Fibrinogen (Fbg) [ second ]
Calculated Parameters:
Fibrinogen Concentration [ mg/dL ]
4) Deficient Factor Assay (II, V, VII, VIII, IX, X, XI, and XII factors) [ second ]
Calculated Parameters:
Activity Percent [%]
5) Thrombo Test (TTO) (Selectable depending on the destination) [ second ]
Calculated Parameters:
Activation Percent [%]
INR [–]
6) Normotest (NT) (Selectable depending on the destination) [ second ]
Calculated Parameters:
Activation Percent [%]
INR [–]
7) Thrombin Time (TT) (Selectable depending on the destination) [ second ]
8) Coagulation Curve
Coagulation curves are obtained and analyzed for the parameters of above-mentioned
parameters 1) through 7).
9) Anti-thrombin-III (AT-III) Activation Percent [%]
10) Plasminogen (PLG) Activation Percent [%]
11) a2-plasmin Inhibitor (a2PI) Activation Percent [%]
12) Protein C (PC) Activation Percent [%]

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13) FDP Concentration [ µg/mL ]
14) D-Dimer Concentration [ µg/L ][ mg/L ]
15) Protein C clotting (PCc) Activation Percent [%]
16) Heparin Concentration [ IU/mL ]
17) Factor VIII chromogenic (F VIII CH) Activation Percent [%]

(2) Fbg Measurement Range


Measuring is possible from 25 mg/dL to 1000 mg/dL of the fibrinogen concentration. (In case of
450 mg/dL or above, measurement is performed with automatic re-dilution in high Fbg
concentration mode, and in case of 50 mg/dL or less, in low Fbg concentration mode.)

(3) Measurement Time


1) Maximum Measurement Time in Standard Mode
PT, Fbg: 100 seconds
Others: 190 seconds
2) Maximum Measurement Time in Automatic Extended Mode
All Parameters: 600 seconds

(4) Accuracy
When control plasma N is measured consecutively 10 times, measurement error of the average
time (second) should lie within the following ranges. (The ambient temperature must be 25 ±
10°C.
PT: ± 8 % or less
APTT: ± 8 % or less

(5) Reproducibility
Coefficient of variation, when control plasma N for 1) ~ 9) and standard plasma of 10 ~ 30 µg/mL
concentration for 10), 11) are measured consecutively 10 times, should fall within the following
ranges:
1) PT, APTT [ second ] CV 2 % or less
2) TTO, NT [ second ] CV 4 % or less
3) Fbg [ second ] CV 4 % or less
4) Factor determination [ second ] CV 5 % or less
5) TT [ second ] CV 10 % or less
6) AT-III [ second ] CV 5 % or less
7) PLG [ second ] CV 5 % or less
8) a2PI [ second ] CV 5 % or less
9) PC [ second ] CV 5 % or less
10) FDP [ µg/mL ] CV 10 % or less
11) D-Dimer Plus [ µg/L ] CV 10 % or less
Advanced D-Dimer [ mg/L ] CV 10 % or less
12) PCc [%] CV 6% or less
13) Heparin [ IU/mL ] CV 5 % or less
14) F VIII CH [%] CV 5 % or less

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(6) Stability
1) Temperature Stability
Variation of measurement at 15°C (C15) or 35°C (C35) from that at 20 ~ 25°C (C25) falls within
the following ranges, when this formula is used.
C15 (or C30) - C25
x 100
C25
PT, APTT [ second ] ± 8 % or less
Fbg, TTO, NT [ second ] ± 10 % or less
AT III [%] ± 10 % or less
D-Dimer [ µg/mL ] ± 20 % or less

2) Stability within-a-day
Variation of measurement at the time of 2, 4 and 8 hours from that at 30 minutes after the
power is turned on (initial value) falls within the following ranges. The ambient temperature
at the time of measurement should be within the specified range. Temperature variation
must be within 5°C.
(Measurement after 2, 4 or 8 hours) - (Measurement at 30 minutes)
x 100
(Initial value)
PT, APTT [ second ] ± 5 % or less
Fbg, TTO, NT [ second ] ± 10 % or less
AT III [%] ± 10 % or less

3) Stability against Power Source Variation


Variation of measurement (Activation % for AT III) when the rated voltage changes at
±10 % falls within the following ranges.
(Measurement at + 10 % or - 10 %) - (Measurement at rated voltage)
x 100
(Measurement at rated voltage)
PT, APTT [ second ] ± 8 % or less
Fbg, TTO, NT [ second ] ± 10 % or less
AT III [%] ± 10 % or less

(7) Analysis Mode and Sample Throughput


1) Analysis Mode
15 Parameters At-random Analysis Mode
PT, APTT, Fbg, TTO, NT, TT, 8 factors, AT III, PLG, a2PI, PC, D-Dimer, FDP
2) Sample Throughput (When the samples are continuously measured for 2 hours.)
PT single analysis: Approx. 120 tests/hour
PT/APTT simultaneous analysis: Approx. 80 tests/hour
PT 40 test, APTT 24 tests, Fbg/TT 8 tests, AT III 8 tests:
Approx. 40 samples/hour
(8) Time Resolution
Time resolution is as follows depending on the elapsed time from the start of measurement.
2 - 120 seconds: 0.1 second
120 - 240 seconds: 0.2 seconds
240 - 600 seconds: 1.0 second

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(9) Compensation functions
1) Setting of Coagulation Detection End Point
The coagulation detection point can be set every 1 % within the range of 2 to 80 %,
enabling the data calibration.
2) External compensation Function
The measured data is corrected with the linear equation.

(10) Required Volume of Plasma and Reagent


The required amount of plasma of sample for each parameter and the required volume of the
measurement of one sample are shown below. (Unit in µL):
Parameters
PT APTT Fbg TTO NT TT AT-III PLG a2PI PC FDP D-Dimer PCc Heparin F VIII CH
Plasma 50 50 10 20 10 100 16 16 16 15 10 50 5 20 10
(Sample)
Buffer 90 30 40 112 112 112 15 80 90
PT 100
APTT 50 50
R Fbg 50
E TTO 125
A NT 125
G TT 50
E CaCl2 50 50
N Activator 175 175 175 150 50
T Substrate 33 35 35 34 40 120
S Stabilizer 150
Accelerator 25
Latex 24 150
reagent
AT III 20
Factor Xa 170
Factor X 40
Factor IXa 40

Additionally, approximately 28 mL of distilled water and approximately 400 µL (at the maximum) of rinsing
solution (CA CLEAN) are required for rinsing per test.

1.4.3 Functions
(1) Sample Tube Transportation Function
Sample tube is transported from the feeder unit to the sample incubation unit by the Slide
Catcher Method.

(2) Reaction Tube Feeding Function


1) Reaction Tube Feeding Method: Fed automatically by Hopper
2) Number of Reagent Tubes: Max. 300 tubes
3) Kinds of Reaction Tube: Tube SU-40 (for CA-1000)

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(3) Sample Plasma and Reagent Dispensing Function
One dispensing pipette with the heating function moves up and down, traverses, and dispenses
the sample and the reagent.
1) Temperature Control Accuracy (Reagent Pipette)
37.0 ± 1.0°C (at ambient temperature of 15 ~ 30°C)
2) Waiting Time for Setting Temperature: Within 30 minutes
3) Volumetric Method
Sample and reagent are aspirated, dispensed and rinsed by the syringe.
4) Volumetric Syringe: 2 (for sample and reagent)
5) Pipette: 2 (for sample and reagent)

(4) Liquid Surface Detection Function


The pipette has the liquid surface detection function, so that it senses the meniscus
automatically and then stops at a certain depth of the sample or the reagent.
(5) Temporary Sampling Function
For the cap piercing analysis, temporary sampling is performed using the sample plate (molded
product).
1) Number of well in Sample Plate: 250 wells
2) Sample Volume: Max. 500 µL
3) Dead Volume: 50 µL
(6) Sampler Function
1) Sample Storing Method: Sysmex Rack
2) Maximum Sample Storage: 5 rack (50 samples)
(Additional samples can be set when required.)
3) Sample Cooling Function: None
4) Sample ID Reading Function
Sample ID No. can be read by the Bar Code Reader.
5) Applicable Collection Tube or Sample Cup
Collection Tube: 15 mmOD x 75 mm (length)
12 mmOD x 75 mm (length)
Sample Cup: capacity of 2 mL or 4 mL
6) Dead Volume
Inner diameter Plasma volume Total blood volume
Collection Tube With cap 9.4 mm 350 µL 700 µL or more
(centrifuged 14 mm 850 µL 850 µL or more
blood sample) Without cap 9.4 mm 250 µL -----

14 mm 700 µL -----

With cap 9.4 mm 700 µL 700 µL or more


Collection Tube 14 mm 700 µL 700 µL or more
(plasma only) Without cap 9.4 mm 200 µL -----

14 mm 500 µL -----
Sample Cup Closed 100 µL -----

Open 50 µL -----

CA-1500 S/M 1-8 December 13, 2007


(7) STAT Sample Measurement Function
1) The specified sample in the STAT Sample Rack can be analyzed, interrupting the usual
analysis.
2) Within 5 minutes from the interruption by the STAT sample analysis, the analysis result can
be output (when the single parameter is analyzed).
3) Number of STAT sample: 5 samples
4) Dead Volume: Applies to the table given in "(6) Sampler function."

(8) Micro Sample Measurement Function


1) For micro-sample measurement, primary sampling is not performed and directly dispense
sample in a reaction tube for a test. (When preparing diluted sample, the sample plate is
used.)
2) Micro sample measurement is possible for normal sample, calibrator, and control plasma.

3) Reanalysis mode is not available as the dispensed sample is for one test only.
When the sample is in the STAT holder it is possible to program the reanalysis, but when the
sample is in a sample rack it is impossible to analyze the sample as the rack is already
shifted.

4) Reflect test is not assigned, as the Reflect key on the work list entry screen is not available.

5) Micro-sample measurement is not possible for the sample in the closed collection tube, as
multiple sample aspiration is not possible.

6) “Test on hold” setting in the Alarm Setting is not effective and the analysis is automatically
interrupted by the reagent shortage.

(9) Reagent Storage Function


1) Reagent Storage Method: Stored in the reagent rack
2) No. of holes of the reagent rack: Maximum 20 kinds of reagent bottles (14 kinds of
control)
3) No. of holes of the others: 5 (3 for buffer and 2 for rinsing solution)
4) Usable container: DADE Reagent Bottle can be set.
(Except the container for INNOVIN. The outer diameter
of the reagent bottle should be less than 31.0 mm, and
also, if the inner diameter is too small, use the reagent
bottle adapter).
5) Reagent Cooling Function: All reagents can be cooled.
6) Temperature Control Accuracy: Within 15 ± 2°C (room temperature: 15 ~ 30 °C)
7) Waiting time for setting temperature: Within 30 minutes
8) Reagent Mixing Function: 4 holes (C7 – C10)
9) Dead Volume:
Dade Container: 900 µL
Sample Cup: 100 µL
10) Same Reagent, Simultaneously Storage Function:
Reagents used for the same parameter can be simultaneously set at three positions.

CA-1500 S/M 1-9 December 13, 2007


11) Reagent Information Input Function:
Information on each reagent (Reagent ID number, Reagent name, Lot No, Term of Validity,
Volume, etc.) can be manually input.
12) Condensation Removing Function (in the cooling unit):
The cooling unit provides a condensation removing function.

(10) Detection Function


1) Principle of Measurement
Activation Method: Scattered Light Detection Method
(measuring wave length 660 nm)
Chromogenic Method: Transmitted Light Detection Method (Colorimetric Method)
(measuring wave length 405 nm)
Immunization Nephelometry: Transmitted Light Detection Method
(measuring wave length 575/800 nm)
2) Number of Detectors
Scattered Light Detection Method: 8 detection wells
(High and Low sensitivity automatic switching)
Transmitted Light Detection Method: 4 detection wells
3) Number of Incubation wells: 14 wells
4) Temperature Control Accuracy
Detection Well: Within 37.0 ± 1.0°C
Incubation Well: Within 37.0 ± 1.0°C
(Ambient temperature: 15 ~ 30°C)
5) Waiting Time for Standby Temperature: Within 30 minutes

(11) Pipette Rinsing Function


1) Rinse Cup: Rinse chamber
2) Rinsing Function: Pipette is rinsed by controlling the syringe and the solenoid valve, with
applying the pressure on Rinse Chamber and the vacuum on Waste
Chamber.

(12) X, Y, Z Driving Function


Pipette and sample catcher mechanism on the head unit (Z axis) is driven by the XY-axis
mechanism to dispense sample and reagent and transfer and discard the reaction tubes.
1) XY-axis Mechanism: Linear Slider driven by stepper motor
2) Z-axis Mechanism: Pipette and sample tube catcher are driven by one motor.

(13) Mixing Function


After dispensing the reagent, the reaction tube is vibrated to mix the plasma and reagents.

(14) Sample Data Storage Function


1) Contents of Data
(a) Measurement data
(b) Setting Values
(c) Quality Control Data
(d) Date (year, month, day, hour, minute)
2) Memory Capacity
(a) Data of 1000 samples (including the coagulation curve)
(b) Quality Control Data

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(15) Display and Input Functions
1) Display Type:
Graphic panel display + touch panel using a 9.5 inch LCD
2) Displayed Data
(a) Date
(b) Measurement Conditions, Analysis Status, Results
(c) Stored Sample (Stored sample list, Date, Time, Sample ID number, Parameter name,
Measured data, Coagulation curves)
(d) Quality Control (QC data, QC chart)
(e) Standard Curve (SC data, SC chart)
(f) Operation Message
(g) Error Message
(h) Maintenance Information and Various Setting Values
(i) Temperature of Incubation Well, Heater Pipette, Reagent Cooler
3) Input Method:
Change, select, and set functions on each screen by LCD touch panel method.

(16) Printing Function


1) Printing Method: Graphic print by an external printer
2) Printed Data
(a) Analysis Results (Date, Time, Sample ID number, Test name, Test data, Coagulation
curve, Analysis data)
(b) Stored Sample Data (the same as the measured data)
(c) Quality Control (QC data, QC chart)
(d) Standard Curve (plot data, chart)
(e) Maintenance Information and Various Setting Values
(f) Screen Hard Copy

(17) Quality Control Function


1) Applicable parameters: Maximum 25 parameters
2) L-J or X-bar control is possible using control material.
3) Number of stored files: 20 files for each test
4) Number of data points: 540
5) Westgard Rule Check Function: 6 kinds (1-2s, 1-3s, 4-1s, R-4s and 10x) can be checked.
6) Control plasma can be set in the reagent holder or sampler.

(18) Select Function


1) Measurement Modes
(a) Random Access Measurement Mode
15 parameters are selected from 25 parameters and the 15 parameters are measured at
random.
(b) Programmable Measurement Mode
12 parameters in 25 parameters are measured with changing the measurement order.
(c) Replication Mode
The same sample is measured twice (or more) and the mean value is determined to be
the measurement result. However, the throughput is less than half number of that of
ordinary measurement.
2) Settings
(a) Sample ID Number (15 digits)
(b) Date, Time

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3) Output
Automatic transfer or Manual transfer can be set.
4) Stored Data Processing
Displaying and printing the stored data is possible.
5) Maintenance
Customer maintenance: Replication setting, display of standard curve data, setting of
abnormal data range
Service maintenance: Maintenance by service mode menu, system tests, memory
Initialization, hardware adjustment, system setup

(19) Standard Curve Setting Function


Standard curve of seven parameters (including 12 programmable channels) can be set at 6
points or less within the measurable range. Setting Standard Curve is performed by the Auto
dilution or Manual Entry. Setting should be given to each parameter individually. The
simultaneous multi-parameter analysis is available. Standard plasma can be set in the reagent
holder or sampler during analysis.

(20) Error Alert Function


1) Unit Error monitoring function
(a) Temperature of heater section
(b) Present or absence of sample plate
(c) Shortage of reagent
(d) Presence or absence of the sample collection tube
(e) Shortage of buffer or rinse solution
(f) Overflow from the waste bottle
(g) Operation of mechanical parts
(h) Operation of printer
(i) Shortage of printer paper
(j) Serial output
(k) Other self-diagnosis by service mode
2) Sample Abnormality Monitor Function
(a) Upper and lower limit judgment
Display when the test data exceeds the preset range.
Display the upper limit (or lower limit) when the test data exceeds the report limit.
(b) Automatic re-dilution Analysis (for the dilution analysis parameter only)
(c) Reflex Testing
(21) External Input / Output Function
The I/O terminal in accordance with RS-232C is provided as bit serial voltage I/O.
(22) STAT Sample Handling Function
Prior test is performed by inserting a rack with the STAT samples which interrupting the routine
measurement sequence.
(23) Duplicate Measurement Function
The function to measure the same sample twice is provided. This setting is possible for each
test parameter. (The same sample can be analyzed 10 times in Service Mode.)
(24) Programmable Channel Measurement Function
In addition to the standard test parameters, customer setting parameters can be tested by
setting the amount of sample and reagent, test procedures (test protocol).

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(25) Sample Dilution Measurement Function
Measurement is performed with automatic dilution to pre-assumed concentration.
The factor determination method conforms to the multi-dilution analysis mode.
(26) Protection Function
1) Over-heat protection thermal fuse (Pipette Unit and Detector Block)
2) Mechanical stop switch
3) Light shield cover open/close switch
4) Pipette protection sensor
(27) Floppy Disk Drive Function
The following functions are provided for 3.5 inches floppy disk.
1) Backup of quality control data
2) Backup of stored sample data
3) Backup of calibration curve data
4) Program version up
5) Sample surveying function
(28) Hard Disk Function
The hard disk is installed to store the data of the tested samples.
(29) Displayed Languages
Six languages can be displayed by installing other language program (optional).
(Before shipment, only Japanese and English can be displayed.)

1.5 ACOUSTIC NOISE LEVEL


Noise level should be within the following values. The measuring position is 1 meter from the front of
the product.
(1) Stand-by status: 58 db or less
(2) Measuring operation status: 60 db or less
Temporary noise are produced on occasions, such as 64 db or less noise of 5 seconds continuous
operation in X-Y-Z mechanism.

1.6 ENVIRONMENTAL CONDITIONS

1.6.1 Operating Environment

(1) Ambient Temperature: 15°C ~ 30°C


(2) Relative Humidity: 30 % ~ 85 % (non-condensing)
(3) Atmospheric Pressure: 70 kPa ~ 106 kPa
(4) Place to be installed: Avoid direct sunlight, dust, vibration and acid vapors.

1.6.2 Power Source (Electric Ratings)

(1) Rated Voltage


AC 100, 117, 220 or 240 V ± 10%
(2) Frequency
50 or 60 Hz ±1 Hz

CA-1500 S/M 1-13 December 13, 2007


1.6.3 Reagent Recommendation

The instrument specification performance described in this section are obtained using the following
reagents.
(1) PT measurement: Thromboplastin C plus
Thromboplastin IS
Dade INNOVIN
Thromborel S
(2) APTT measurement: Data-Fi APTT
Data-Fi APTT(FS)
Actin FSL
Pathrontin SL
20 mM Calcium Chloride Solution
25 mM Calcium Chloride Solution
(3) Fbg measurement: Data-Fi Fibrinogen Thrombin
(4) Buffer: Owren's Veronal Buffer
(5) Control plasma: Dade Ci-Trol Level I, II, III
Dade Control Plasma N, P
(6) TTO measurement: CA Series Complex Factor TTO
(7) NT measurement: CA Series Complex Factor NT
(8) TT measurement: Data-Fi Thrombin Time
(9) AT III measurement: Dade Antithrombin III Kit
(10) a2PI measurement: Dade a 2-Antiplasmin Kit
(11) PLG measurement: Dade Plasminogen Kit
(12) PC measurement: Dade Protein C Kit
(13) FDP measurement: Lpia FDP (Daiayatron Co., Ltd.)
(14) D-Dimer measurement: Dade D-Dimer Plus
Dade Advanced D-Dimer
(15) PCc measurement: Protein C Reagent, coagulometric
(16) Heparin measurement: Berichrom Heparin
(17) F VIII CH measurement: Factor VIII chromogenic assay

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