LIFTONIN®- XPRESS

The Instant Wrinkle Minimiser

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 Wrinkles – Marks of Life

• Signs of the loss of youth

• Direct consequences of skin ageing (loss of elasticity/loss
of tissue depth)
• Consequences of using muscles for facial expressions
• Noticeable from age 30 - 40 onwards
• Dependent upon ethnic group
• Reasons for using anti-ageing cosmetics
→ 50 – 60 % of the users of anti-ageing cosmetics
primarily seek to reduce wrinkles
→ 46 % of the women surveyed and 33 % of the men
value their youthful appearance

Looking for a high-performance wrinkle smoother with immediate effects?

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LIFTONIN®- XPRESS in a Nutshell
The Instant Wrinkle Minimiser

• Quickly and reliably minimises various types

of wrinkles on the face and body
• Improves the wrinkle micro relief of the face
and body
• Provides immediately noticeable, intense
and long-lasting physical tightening effects
• Up to 74% less wrinkles around the eye area
in just one hour!
• Highly effective in aqueous solutions as well
as in creams
• Based on edible film technology from the
food industry

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 Classification of Wrinkles

According to progression of skin ageing

(Glogau)
• Group I: Mild skin ageing; no wrinkles, smooth,
even skin
• Group II: Moderate skin ageing; wrinkles only
appear during animated facial expressions
• Group III: Advanced skin ageing; wrinkles are also
visible when the face is relaxed
• Group IV: Severe skin ageing; the entire surface
of the skin is covered in wrinkles

According to wrinkle type

• Fine lines / Atrophic wrinkles
• Actinic wrinkles / Elastotic wrinkles
• Dynamic wrinkles / Expression wrinkles
• Static wrinkles / Gravitational wrinkles

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 Wrinkle Types
Atrophic / Fine Wrinkles

• Caused by intrinsic (natural,

chronological) skin ageing
• Fine lines and wrinkles in the skin micro
relief form a typical pattern
• Atrophy of the dermis (loss of tissue)
increases with age → the skin becomes
thinner and has less collagen and elastic
fibres.
• Fine lines become deeper with age and
run anisotropically (parallel in one
direction)
• Can be well treated with cosmetics

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 Wrinkle Types
Actinic / Elastotic Wrinkles

• Caused by extrinsic skin ageing (external

factors such as sun exposure, visiting
solariums, smoking tobacco)
• Exposure to the sun → collection of abnormal
connective tissue fibres (Solar Elastosis) →
deep wrinkles
• Elastotic wrinkles are permanent and appear
primarily on the face, neck and hands
• Actinic wrinkles become very deep with age
and form a typical pattern
• These can be cosmetically well treated in
early stages

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 Wrinkle Types
Expression Wrinkles / Gravitational Wrinkles

Expression wrinkles (dynamic wrinkles)

• Formed by the continuous contraction of
the expression muscles
• These are also visible when the muscles
are relaxed in later stages
• Wrinkles around the eyes, on the
forehead, around the nose and the
mouth
Gravitational wrinkles (static wrinkles)
• Formed by the continuous effects of
gravity on the tissue
• Permanently visible, very deep and
resistant
• Nasolabial wrinkles, Marionette lines

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LIFTONIN®- XPRESS – Function and
Components of a modern Lifting Active Ingredient

• Well-balanced Polymer network made from

sustainable raw materials and biopolymers,
based on the development know-how of edible
films
• Fast, intense and long-lasting physical
tightening effect
• Minimises various types of wrinkles on different
parts of the body and face
• The tightening effect is visible, measurable and
perceivable
• Effective in various cosmetic bases

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Film Matrix made from near-natural Polymers
Cellulose Derivatives and Maltotriose Biopolysaccharides

Hydroxypropyl Methyl Cellulose

• Degree of polymerisation and degree of
substitution determine the physical characteristics
• An ideal mix of Cellulose derivatives for the best
tightening performance
Maltotriose Biopolymer (Pullulan)
• Biotechnologically manufactured using
Aureobasidium pullulans
• Pullulan protects A. pullulans from drying out
Processing
• Polymers are mixed and processed into a slurry
• The slurry is extruded under pressure and
processed into film in a drying tunnel

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Porphyridium cruentum
Natural Phycocolloids as Survival Strategy

• Micro-alga, cells 6 - 10 µm in diameter

• Crimson red algae, Rhodophytes phylum
• A natural occurrence in the salty environment of the
Red Sea
• A unique protection mechanism against moisture
loss, salt stress and UV radiation; continuous
production of a mucous made from phycocolloids
that surround the cell like a gel capsule
• Macromolecular phycocolloids support the tightening
effect
• Porphyridium cruentum is cultivated free of
contamination under optimal conditions in a
photobioreactor, and extracted using hot water and
then lyophilised

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LIFTONIN®- XPRESS
The Instant Wrinkle Minimiser

Scientifically Proven Effects

• Smoothes various types of wrinkles
around the eye area, forehead and hands
(in-vivo studies)
• Improves the micro relief in the eye area,
hands and arms (in-vivo studies)
• Provides an immediately noticeable and
long lasting tightening effect (in-vivo study)

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LIFTONIN®- XPRESS smoothes Wrinkles &
improves Microstructure in the Eye Area (in-vivo Study)

Aim: To verify rapid wrinkle smoothing in

the eye area upon application of
LIFTONIN®- XPRESS.
Method: Fringe Projection (wrinkle volume
and average roughness)
Implementation: 21 female subjects;
49 - 64 years of age (average 59);
Gel with 3 % LIFTONIN®- XPRESS vs.
Placebo (0 % LIFTONIN®- XPRESS);
Single application in the area around the
eyes; measurement before and 1 hour after
application
Result: LIFTONIN®- XPRESS significantly
smoothes the wrinkle volume (- 31%) as
well as the roughness (- 12%). The
maximum reduction of the wrinkle volume
amounted to 74%.
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LIFTONIN®- XPRESS:
visible Lifting-Effect after just one hour!

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LIFTONIN®- XPRESS smoothes Wrinkles
in the Forehead Area (in-vivo Study)

Aim: To verify a rapid wrinkle smoothing of

forehead wrinkles following application of
LIFTONIN®- XPRESS.
Method: PRIMOS (Maximum Roughness
Depth Rmax)
Implementation: 20 female subjects;
37 - 70 years of age (average 51);
Gel with 1% LIFTONIN®- XPRESS;
Single application in the forehead area;
measurement of the wrinkle depth before
and 1 hour after application
Result: LIFTONIN®- XPRESS significantly
smoothes the forehead wrinkle depth (- 5%).
The maximum reduction of the wrinkle depth
amounted to 19%.

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LIFTONIN®- XPRESS smoothes the
Forehead, even at low Dosage!

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 LIFTONIN®- XPRESS smoothes the
Wrinkle Microrelief of the Underarm (in-vivo Study)

Aim: To verify the smoothing of the micro

relief upon application of LIFTONIN®- XPRESS.
Method: PRIMOS (Averaged Skin Roughness
RZ)
Implementation: 20 female subjects;
35 - 65 years of age (average 46);
Three gel bases with 1% LIFTONIN®- XPRESS
vs. Placebo (0% LIFTONIN®- XPRESS);
Single application on the inside of the underarm
(measurement of the roughness) and on the
hands (production of 3D images) before and 30
minutes after application.
Result: LIFTONIN®- XPRESS significantly
improves the wrinkle micro relief. The maximum
smoothing effect amounted to 22%.

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 Smooth Hands thanks to
LIFTONIN®- XPRESS!

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 LIFTONIN®- XPRESS provides an
immediately noticeable, long lasting tightening effect
(in-vivo Study)
Aim: Determination of the subjectively perceived
tightening effect.
Method: Controlled application test with
questionnaire
Implementation: 20 female subjects;
assessment of the tightening effect after single
application in the eye area;
a) Roll-on with 2% LIFTONIN®- XPRESS: 37 -
70 years of age (average 51)
b) Eye cream with 2% LIFTONIN®- XPRESS:
36 - 65 years of age (average 49)
Result: LIFTONIN®- XPRESS works in creams
as well as in aqueous formulations.
The tightening effect is fast, intense and still
noticeable even after six hours.

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Application

Areas of application
Lifting products and tightening face and body care products. Suitable for gels and
emulsions (O/W and W/O).

Recommended use level

0.5 - 3%

Preservative system
0%

Solubility and Processing

Water dispersable; disperse LIFTONIN®- XPRESS in aqueous phase while stirring.
Mix until hydrated.

Natural cosmetics
-

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Technical Information

Test Point Method Specification

Appearance TP 001 Flakes

Colour TP 002 White to Yellow

Total Plate Count TP 040 ≤ 500 CFU/g
Moisture Content TP 061 5 - 10 %

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Registration

EU
Hydroxypropyl Methylcellulose, Pullulan, Porphyridium Cruentum Extract

USA
Hydroxypropyl Methylcellulose, Pullulan, Porphyridium Cruentum Extract

Japan
Hydroxypropyl Methylcellulose, Pullulan, Porphyridium Cruentum Extract

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Marketing Concepts and Claims

• Up to 74% less eye wrinkles in just one hour? Yes, thanks to LIFTONIN®- XPRESS
• 4D face lifting: LIFTONIN®- XPRESS immediately tightens and smoothes various
types of wrinkles in a highly effective manner
• Tightening décolletage care: LIFTONIN®- XPRESS immediately tightens, CellActive®-
FORM firms the tissues and ensures that the skin becomes elastic again
• Tightening body cream: LIFTONIN®- XPRESS also works within minutes in creams
• Would you like to wait just one hour and reduce eye wrinkles by up to 74%?
Would you like to wait just four weeks and look up to six years younger?
Yes, thanks to LIFTONIN®- XPRESS and PROTEOLEA®

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Information

Presentation LIFTONIN®- XPRESS 06/12

Utilisation of this document or parts thereof as well as product names for commercial or
industrial applications is subject to explicit written approval by RAHN AG. This information is
based on our own experience to date and we believe it to be reliable. It is intended only as a
guide to use at your discretion and risk. We cannot guarantee favourable results and assume
no liability in connection with its use, or the use of the methods or products described. None of
this information is to be taken as a license to operate under, or a recommendation to infringe
patents.

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