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has been done, but the organs that have been manufactured are 4 Miller JS, Stevens KR, Yang MT, et al. Rapid casting of patterned vascular
miniature and not complex.16 3D printing gives rise to the pos- networks for perfusable engineered three-dimensional tissues. Nat Mater
2012;11:768–74.
sibility that entirely new organs not in the shape of the parent 5 Jeong JE, Chan V, Cha C, et al. “Living” Microvascular Stamp for Patterning of
organ may be produced. It is conceivable that a ‘liver’ or ‘pan- Functional Neovessels; Orchestrated Control of Matrix Property and Geometry. Adv
creas’ could be produced as, for example, a tube-shaped organ. Mater 2012;24:58–63.
At the present time, however, the impact of 3D printing in 6 Leukers B, Gulkan H, Irsen SH, et al. Hydroxyapatite scaffold for bone tissue
engineering made by 3D printing. J Mater Sci Makter Med 2005;16:1121–4.
medicine is still small, but it has the potential to grow into an
7 Mannoor MS, Jiang A, James T, et al. 3D Printed bionic ears. Nano Lett
enormously beneficial technology. The entire 3D printing indus- 2013;13:2634–9.
try is currently a $700 million industry, with only $11 million 8 Haumont T, Rahman T, Sample W, et al. Wilmington Robotic Exoskeleton: A Novel
invested in medical applications (roughly 2%). In the next Device to Maintain Arm Improvement in Muscular Disease. J Pediatr Orthop B
10 years it is expected to grow to an $8.9 billion industry, of 2011;31:44–9.
9 Zopf DA, Hollister SJ, Nelson ME, et al. Bioresorable Airway Splint Created with a
which $1.9 billion is projected to be for medicine.17 Three-Dimensional Printer. N Engl J Med 2013;368:2043–45.
10 Fielding GA, Bandyopadhyay A, Bose S. Effects of silica and zinc oxide doping on
Acknowledgements The authors thank Michael Armbruster of incept3D in San mechanical and biological properties of 3D printed tricalcium phosphate tissue
Diego, California who provided a figure and a set of 3D printed glasses. For further engineering scaffolds. Dent Mater 2012;28:113–22.
information see (http://www.incept3D.com). 11 Robotics Research Group. Bldg 106 Albany. Auckland, New Zealand. http://www.
Contributors All authors took part in the development of the manuscript including mechatronics.massey.ac.nz
the writing of the manuscript. MCvanL also provided samples of 3D printed 12 Symes MD, Kitson PJ, Yan J, et al. Integrated 3D-printed reaction ware for chemical
sculptures for use in figure 2. synthesis and analysis. Nat Chem 2012;4:349–54.
13 Faulkner-Jones A, Greenough S, King JA, et al. Development of a valve-based cell
Competing interests None.
printer for the formation of human embryonic stem cell spheroid aggregates.
Provenance and peer review Not commissioned; externally peer reviewed. Biofabrication 2013;5:015013.
14 Csete M. Translational prospects for human induced pluripotent stem cells. Regen
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These include:
References This article cites 11 articles, 0 of which you can access for free at:
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Notes