DRUG STUDY

Drug Name Mechanism of

Indication Side Effects/ Adverse Effect Contraindication Nursing Consideration
Action

Generic Name: Inhibits DNA Treatment of CNS: Headache, dizziness, Contraindicated Assess patient with allergy to fluoroquinones, renal
Levofloxacin gyrase replication complicated and insomnia, fatigue, somnolence, with allergy to impairment, seizures, lactation, pregnancy
in susceptible uncomplicated blurred visions fluoroquinones,
gram (-) and skin and skin GI: nausea, vomiting, dry mouth, lactation Assess skin color, lesions, temperature, orientation,
Chemical gram (+) bacteria structure diarrhea, abdominal pain (occurs reflexes, affect; mucous membranes, bowel sounds,
Classification: infections caused less with this drug than Use cautiously LFTs, renal function tests, blood glucose (patients with
Fluoroquinolone by susceptible ofloxacin), constipation, with renal diabetes)
bacteria flatulence, abnormal liver impairment, Arrange for culture and sensitivity tests before
Therapeutic Interferes with function. seizures, beginning therapy
Classification: pregnancy
DNA Continue therapy as indicated for condition being
Antibiotic
GU: Abnormal renal function, treated
acute renal failure, UTI, urine
retention. Administer oral drug without regard to meals with a
Prevents cell glass of water; separate oral drug from other cation
reproduction HEMATOLOGIC: Elevated BUN, administration, including antacids by at least 2 hours.
serum creatinine, and alkaline
phosphatase; neutropenia, Ensure that patient is well hydrated during course of
anemia therapy
Discontinue drug at any sign of hypersensitivity (rash,
photophobia) or at complaint of tendon pain,
OTHER: Fever, rash, inflammation, or rupture
photosensitivity, muscle and joint Monitor clinical response, if no improvement is seen or
tenderness, increased serum a relapse occurs, repeat culture and sensitivity test.
glucose
Advise the client to drink plenty of fluids while using
this drug.
Instruct the client to report rash, visual changes,
severe GI problems, weakness, tremors