Clinical Chemistry (060513310)

Assignment 1
Name: ID: Section:

Part One: Please answer the multiple choice questions in chapter 8 (Amino
acids and Proteins in pages 196 -198) in your book in the following tables.

Answers
Chapter 8 / Level 1
1 2 3 4 5 6 7 8 9 10

11 12 13 14 15 16 17 18 19 20

Chapter 8 / Level 2
1 2 3 4 5

1
Part Two: Please read the following case study carefully and answer the related
questions.

Judy, a 40-year-old woman with a past history of kidney infections, was seen by her
physician because she had felt lethargic for a few weeks. She also complained of
decreased frequency of urination and a bloated feeling. The physician noted
periorbital swelling and general edema including a swollen abdomen.

The followings are the results of urinalysis and chemistry tests.

Urinalysis
Macroscopic
Color: Yellow Ketones: Neg
Appearance: Cloudy/frothy Bilirubin: Neg
Specific gravity: 1.022 Blood: Neg
pH: 7.0 Urobilinogen: Normal
Protein: 3+ (500 mg/dL) (SSA: 4+) Nitrite :Neg
Glucose: Neg Leukocyte esterase: Neg
Microscopic
WBC:s 0–3/HPF
RBCs: 0–1/HPF
Epithelial cells:
Rare squamous/HPF
Rare renal tubular epithelial/HPF
Casts: 0–3 Hyaline/LPF
0–1 Renal tubular epithelial/LPF
0–1 Granular/LPF
0–1 Waxy/LPF
0–1 Fatty/LPF
Other: Occasional oval fat bodies

Chemistry
Test Result Reference Range
Protein 5.0 g/dl 6.0–8.3 g/dL
Albumin 2.4 g/dL 3.4–5.0 g/dL

Cholesterol 370 mg/dL <200 mg/dL

BUN 33 mg/dL 7–24 mg/dL

Creatinine 2.1 mg/dL 0.5–1.2 mg/dL

2
Questions:
1. Circle or highlight the abnormal value(s) or discrepant result(s) in the urinalysis.
2. What type of disease/condition would be characterized? by the urinalysis and
chemistry results?
3. What urinalysis result(s) led to your probable diagnosis?
4. Are the a abnormal chemistry tests consistent with the probable diagnosis? Explain
why or why not.

5. Discuss the physiological cause of the edema.

6. What is Judy’s A/G ratio? Is it within the reference range? Is it consistent with the
probable diagnosis?

7. Describe what you would expect to see in this patient’s protein electrophoresis.

Good Luck

Mrs. Haneen Mansour