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CHAPTER 2 SAMPLE SCREENING

QUESTIONS
For an adult patient
After establishing the chief
Making the Diagnosis complaint and history of
Tools for Clinicians to Ascertain Environmental and present illness:
Occupational Health Exposures What kind of work do you
do?
(If unemployed) Do you
OVERVIEW think your health problems
are related to your home or
$FFXUDWH LGHQWL¿FDWLRQ RI WKH SDWLHQW¶V H[SRVXUH FDQ OHDG WR LPSURYHG GLDJQRVWLF other location?
WKHUDSHXWLFDQGUHKDELOLWDWLYHGHFLVLRQVE\WKHFOLQLFLDQDQGUHVXOWLQLPSURYHGSDWLHQW
RXWFRPHV:LWKRXWDQDFFXUDWHGLDJQRVLVWKHFOLQLFLDQPD\GHFLGHXSRQDV\PSWRP (If employed) Do you think
EDVHGWUHDWPHQWWKDWPD\EHOHVVHIIHFWLYH your health problems are
2QFH LGHQWL¿HG D SHVWLFLGH H[SRVXUH LQFLGHQW VKRXOG EH FRQVLGHUHG D SRWHQ related to your work? Are
WLDOVHQWLQHOKHDOWKHYHQWWKDWPD\UHTXLUHIROORZXSHIIRUWVWRORFDWHWKHVRXUFHDQG your symptoms better or
DQ\ DGGLWLRQDO FDVHV %\ LGHQWLI\LQJ WKH VRXUFH RI H[SRVXUH WKH FOLQLFLDQ FDQ DYHUW worse when you are at
IXUWKHUH[SRVXUHLQWKHLQLWLDOSDWLHQWDQGRWKHUH[SRVHGLQGLYLGXDOV3RVWGLDJQRVWLF home or at work?
DFWLYLWLHV DUH LPSRUWDQW WR VXSSRUW D V\VWHPV DSSURDFK WR SHVWLFLGH H[SRVXUH FDVHV Are you now or have you
LQFOXGLQJUHSRUWLQJWKHLQFLGHQW¿OLQJDZRUNHUV¶FRPSHQVDWLRQFODLPDQGFRQGXFWLQJ previously been exposed to
VSHFLDOW\FDUHUHIHUUDOV7KHFOLQLFLDQPXVWDOVREHDZDUHRIVHYHUDOHWKLFDODQGSXEOLF pesticides, solvents or other
KHDOWKFRQVLGHUDWLRQV/DVWO\WKHUHDUHNH\UHVRXUFHVDYDLODEOHWRDVVLVWFOLQLFLDQVDQG chemicals, dusts, fumes,
SDWLHQWVLQGHDOLQJZLWKSHVWLFLGHUHODWHGLOOQHVVHVRULQMXULHV radiation or loud noise?

TAKE INITIAL SCREENING FOR PESTICIDE EXPOSURE For a pediatric patient


$VNLQJWKHSDWLHQWDIHZLQLWLDOVFUHHQLQJTXHVWLRQVLVFULWLFDOIRUPDNLQJDQDFFXUDWH Questions asked of parent
GLDJQRVLVDQGPD\ÀDJWKHQHHGWRWDNHDPRUHH[WHQVLYHH[SRVXUHKLVWRU\*LYHQWKDW or guardian
WLPHFRQVWUDLQWVLQDSULPDU\FDUHVHWWLQJFRPSHWHZLWKWKHQHHGWRLGHQWLI\DSDWLHQW¶V
Do you think the patient’s
SRWHQWLDO (2+ H[SRVXUHV LW LV highly recommended that a few short screening
health problems are related
questions be incorporated into the routine patient intake procedure LQ RUGHU WR
to the home, child care
LGHQWLI\UHOHYDQW(2+H[SRVXUHV16HHWKHSample Screening QuestionsLQWKHVLGHEDU
setting, school or other
location?
OBTAIN DETAILED EXPOSURE HISTORY Has there been any
,IWKHLQLWLDOVFUHHQLQJVXJJHVWVDSRWHQWLDO(2+H[SRVXUHFRQFHUQDGHWDLOHGH[SRVXUH exposure to pesticides,
LQWHUYLHZLVRIWHQQHHGHG$QH[WHQVLYHH[SRVXUHKLVWRU\FDQWDNHXSWRDQKRXUDQG solvents or other chemicals,
SURYLGHVDPRUHFRPSOHWHSLFWXUHRISHUWLQHQWH[SRVXUHIDFWRUV7KHGHWDLOHGLQWHUYLHZ dusts, fumes, radiation or
LQFOXGHVTXHVWLRQVRQRFFXSDWLRQDOH[SRVXUHHQYLURQPHQWDOH[SRVXUHV\PSWRPVDQG loud noise?
PHGLFDOFRQGLWLRQV'DWDFROOHFWLRQJXLGHOLQHVVSHFL¿FWRSDWLHQWVZLWKFRQ¿UPHGDFXWH In what kind of work are the
SHVWLFLGHLOOQHVVHVRULQMXULHVLVSURYLGHGDWWKHHQGRIWKLVFKDSWHURQSDJHV parents and other household
$OWKRXJK WKH IRFXV LV RQ SHVWLFLGH H[SRVXUHV DQG UHODWHG KHDOWK HIIHFWV FRQFXUUHQW members engaged?
QRQSHVWLFLGHH[SRVXUHVQHHGWREHFRQVLGHUHGLQWKHRYHUDOOSDWLHQWKHDOWKDVVHVVPHQW
4XHVWLRQV W\SLFDO RI D GHWDLOHG (2+ KLVWRU\ DUH SURYLGHG LQ Appendix A,
Detailed Occupational and Environmental Exposure History Questions, RQ SDJH
 )RU IXUWKHU LQIRUPDWLRQ RQ WDNLQJ D KLVWRU\ IRU DOO W\SHV RI RFFXSDWLRQDO DQG
HQYLURQPHQWDO KD]DUGV FRQVXOW D JHQHUDO RFFXSDWLRQDO DQG HQYLURQPHQWDO PHGLFLQH
UHIHUHQFHWH[W2RU$JHQF\IRU7R[LF6XEVWDQFHVDQG'LVHDVH5HJLVWU\¶VCase Study in
Environmental Medicine: Taking an Exposure History.

13
CHAPTER 2
Making the Diagnosis
DEALING WITH A SUSPECTED PESTICIDE EXPOSURE
$IWHU FRQGXFWLQJ H[SRVXUH VFUHHQLQJ DQG SRVVLEO\ D GHWDLOHG H[SRVXUH KLVWRU\ WKH
FOLQLFLDQVKRXOGWDNHWKHIROORZLQJVWHSVRQFHWKH\VXVSHFWDSHVWLFLGHSRLVRQLQJ.,W
VKRXOGEHQRWHGWKDWHDFKSHVWLFLGHLQFLGHQWLVDXQLTXHVLWXDWLRQZLWKYDU\LQJOHYHOV
RIVHYHULW\DQGXUJHQF\WKHUHIRUHWKHVHVWHSVDUHQRWDOZD\VDFKLHYHGLQWKHRUGHU
WKH\DUHSUHVHQWHG.,WLVKRZHYHUFUXFLDOWRREWDLQDQGSUHVHUYHDQ\HYLGHQFHRIWKH
H[SRVXUHDVVRRQDVSRVVLEOH.

1. Collect Information on the Pesticide


:KHQ \RX VXVSHFW D SHVWLFLGH SRLVRQLQJ WU\ WR JHW DV PXFK LQIRUPDWLRQ DERXW WKH
SHVWLFLGH V DVSRVVLEOHLQFOXGLQJWKHQDPHRIWKHSHVWLFLGHXVHGWKH(3$SHVWLFLGH
UHJLVWUDWLRQ QXPEHU DQG WKH SHVWLFLGH ODEHO DQGRU WKH 0DWHULDO 6DIHW\ 'DWD 6KHHW
06'6 IRUWKHSHVWLFLGH V .,IWKLVLVDFDVHLQYROYLQJDJULFXOWXUDOZRUNHUVRUUHVLGHQWV
LQ DQ DJULFXOWXUDO DUHD WU\ WR WDON GLUHFWO\ WR WKH IDUP PDQDJHU VDIHW\ FRRUGLQDWRU
RUWKHSHVWLFLGHDSSOLFDWRUWRJHWWKLVLQIRUPDWLRQLQDGGLWLRQWRDGHVFULSWLRQRIWKH
LQFLGHQWLWVHOI.2IWHQDSSOLFDWLRQUHFRUGVZLOOEHPDGHDYDLODEOHLIUHTXHVWHG.8QGHU
(3$¶V:RUNHU3URWHFWLRQ6WDQGDUG &)51 DJULFXOWXUDOHPSOR\HUVDUHUHTXLUHG
WRPDNHWKHQDPHRIWKHSHVWLFLGHDQGWKHODEHODYDLODEOHWRKHDOWKFDUHSURYLGHUVDQG
ZRUNHUVLILWLVUHTXHVWHG.5HIHUWRWKHPDWHULDOHQWLWOHGData Collection on an Acutely
Pesticide Exposed PatientIRXQGRQSDJHV22DWWKHHQGRIWKLVFKDSWHU.

2. Follow Decontamination Procedures


)ROORZWKHGHFRQWDPLQDWLRQSURFHGXUHVDVRXWOLQHGLQChapter 3, General Principles,
EHJLQQLQJRQSDJH2.

3. Collect Evidence of Contamination


2EWDLQ DQ XQODXQGHUHG VDPSOH RI FORWKLQJ WKDW WKH SDWLHQW ZDV ZHDULQJ DW WKH WLPH
RIWKHLQFLGHQWLIDYDLODEOH.3XWLWLQDSODVWLFEDJWRSUHYHQWIXUWKHUH[SRVXUHDQGWR
SUHVHUYHWKHVSHFLPHQVIRUVXEVHTXHQWDQDO\VLVIUHH]LQJLVRSWLPDO.,WFDQEHGLI¿FXOW
WR¿QGDSSURSULDWHFORWKLQJWRVDPSOHLIWKHZRUNHUKDVEHHQLQVWUXFWHGWRJRKRPHDQG
WKRURXJKO\ZDVKKLVKHUFORWKLQJ.,IPRVWFORWKLQJKDVEHHQZDVKHGRULVQRWDYDLODEOH
LWLVOLNHO\WKHSDWLHQW¶VKDWRUVKRHVZRXOGVWLOOEHFRQWDPLQDWHGDQGFRXOGEHDQDO\]HG.

4. Obtain a Urine Sample


,IDQH[SRVXUHVHHPVOLNHO\HLWKHUEDVHGRQWKHKLVWRU\RUWKHFOLQLFDOH[DPREWDLQD
XULQHVDPSOHDQGIUHH]HLW.,IPRUHWKDQRQHSDWLHQWLVH[SRVHGREWDLQDXULQHVDPSOH
IRUHDFKSDWLHQW.)UHH]LQJWKHXULQHDOORZV\RXH[WUDWLPHWRGHWHUPLQHLIWKHVDPSOH
QHHGVWREHDQDO\]HGDQGWRZKLFKODERUDWRU\LWVKRXOGEHVHQW.

5. Order Laboratory Tests


7KH1DWLRQDO3HVWLFLGH,QIRUPDWLRQ&HQWHU 13,& SURYLGHVDOLVWRISHVWLFLGHVWKDWFDQ
EHDQDO\]HGE\FOLQLFDOODERUDWRULHV.7KLVOLVWDQGDOLVWRIDFFUHGLWHGODERUDWRULHVFDQ
EHDFFHVVHGDWhttp://npic.orst.edu/mcapro/PesticidesTestingForExposure.pdf.
,IWKHSDWLHQWDSSHDUVWRKDYHEHHQH[SRVHGWRDQRUJDQRSKRVSKDWHRU1PHWK\O
FDUEDPDWHLQVHFWLFLGHRUGHUFKROLQHVWHUDVHEORRGWHVWVERWKSODVPDDQGUHGEORRGFHOO
WR GHWHUPLQH WKH FOLQLFDO OHYHO RI FKROLQHVWHUDVH DFWLYLW\. 6RPH H[SHUWV UHFRPPHQG
EORRGWHVWLQJLIDFOLQLFLDQEHOLHYHVDQ\VLJQL¿FDQWH[SRVXUHKDVRFFXUUHGUHJDUGOHVV
RIDEDVHOLQHWHVW.8QOHVVDGUDPDWLFGHSUHVVLRQLVSUHVHQWWKHUHVXOWVRISRVWH[SRVXUH
WHVWLQJDUHOLNHO\WREHGLI¿FXOWWRLQWHUSUHWLQWKHDEVHQFHRIEDVHOLQHFKROLQHVWHUDVH
WHVWLQJ. ,Q WKLV LQVWDQFH LW LV DGYLVDEOH WR FRQGXFW SHULRGLF UHWHVWV XQWLO LW DSSHDUV

14
CHAPTER 2
Making the Diagnosis
WKDWWKHFKROLQHVWHUDVHOHYHOKDVUHWXUQHGWRQRUPDO.$³QHJDWLYH´FKROLQHVWHUDVH i.e.,
UHVXOWVZLWKLQWKH³UHIHUHQFHUDQJH´ GRHVQRWUXOHRXWWKHSRVVLELOLW\WKDWWKHSDWLHQW¶V
V\PSWRPVDUHGXHWRSHVWLFLGHVLIWKHSDWLHQWZDVUHDFWLQJWRDSHVWLFLGHRWKHUWKDQ
DQ RUJDQRSKRVSKDWH RU 1PHWK\O FDUEDPDWH RU LI VKH ZDV UHDFWLQJ WR RWKHU LQJUH
GLHQWV LQ WKH RUJDQRSKRVSKDWH RU FDUEDPDWH IRUPXODWLRQ e.g., WKH VROYHQWV SURSHO
OHQWV DQG FDUULHUV LQ WKH SHVWLFLGH SURGXFW IRUPXODWLRQ . +RZHYHU QHJDWLYH UHVXOWV
FRXOGEHPLVLQWHUSUHWHGE\DQHPSOR\HURULQVXUHUWRPHDQWKDWQRH[SRVXUHRFFXUUHG.
3RVWH[SRVXUHFKROLQHVWHUDVHWHVWVQHHGWREHFRPSDUHGWREDVHOLQHSUHH[SRVXUHWHVW
UHVXOWVRUUHWHVWLQJRIFKROLQHVWHUDVHVHYHUDOZHHNVSRVWH[SRVXUH.7KHUHFRYHU\UDWH
IRUGHSUHVVHGFKROLQHVWHUDVHFDQEHHVWLPDWHGWREH.SHUGD\IRUUHGEORRGFHOOV
DQG1.2SHUGD\IRUSODVPD.

6. Consult with the Appropriate Specialists


<RXPD\QHHGWRFRQVXOWZLWKRWKHUVVXFKDVWR[LFRORJLVWVRFFXSDWLRQDODQGHQYLURQ
PHQWDOPHGLFLQHVSHFLDOLVWVDQGLQGXVWULDOK\JLHQLVWVZKRKDYHH[SHUWLVHLQGHDOLQJ
ZLWKFKHPLFDOH[SRVXUHV.3HVWLFLGH,QIRUPDWLRQ5HVRXUFHVLQFOXGLQJWKH$VVRFLDWLRQ
RI2FFXSDWLRQDODQG(QYLURQPHQWDO&OLQLFV S.2 DUHOLVWHGODWHULQWKLVFKDSWHUEH
JLQQLQJRQSDJH2.

7. Schedule/Conduct Patient Follow-up


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WHVWUHVXOWV.2QFHWKHSDWLHQWKDVEHHQFDUHGIRULQIRUPHYHU\RQHHOVHZKRQHHGVWR
NQRZDERXWWKHLQFLGHQWíWKHZRUNHUV¶FRPSHQVDWLRQFDVHPDQDJHUDQGWKHHPSOR\HU
LQSDUWLFXODU.7KHKHDOWKFDUHSURYLGHUPXVWREWDLQWKHHPSOR\HH¶VSHUPLVVLRQEHIRUH
QRWLI\LQJWKHHPSOR\HU.
:KLOHDGLDJQRVLVFDQEHEDVHGRQDJURXSH[SRVXUHIRUWKHSXUSRVHRIWUHDWPHQW
ZRUNHUV¶FRPSHQVDWLRQV\VWHPVJHQHUDOO\GHDOZLWKZRUNHUVRQHDWDWLPH.7KHUHIRUH
WKHFOLQLFLDQPXVWFROOHFWWKHLQIRUPDWLRQQHHGHGWRGRFXPHQWWKHH[SRVXUHV\PS
WRPDWRORJ\DQGFRQ¿UPDWRU\GDWDIRUHDFKLQGLYLGXDOLQYROYHGLQDPXOWLSOHSDWLHQW
SRLVRQLQJ.:KLOHLOOQHVVFRQVLVWHQWZLWKRWKHUPHPEHUVLQDFOHDUO\VLFNJURXSPD\EH
VXI¿FLHQWIRUWKHFOLQLFLDQIDFLQJDQRXWEUHDNLWPD\QRWEHVXI¿FLHQWREMHFWLYHLQIRU
PDWLRQWRHVWDEOLVKFDXVDOLW\IRUDZRUNHUFRPSHQVDWLRQFODLP.

8. Report the Pesticide Incident


a. Contact the Appropriate State Health Agency
3HVWLFLGHH[SRVXUHVDUHUHSRUWDEOHDVKHDOWKLQFLGHQWVDQGRFFXSDWLRQDOLQFLGHQWVPD\
DOVREHUHSRUWDEOHDVDYLRODWLRQRIWKH$JULFXOWXUDO:RUNHU3URWHFWLRQ6WDQGDUG.%RWK
RIWKHVHLPSRUWDQWUHSRUWLQJUHTXLUHPHQWVDUHGLVFXVVHGKHUH.
,IDKHDOWKFDUHSURIHVVLRQDOVXVSHFWVWKDWDSDWLHQWKDVDSHVWLFLGHUHODWHGLOOQHVV
WKHFOLQLFLDQVKRXOGUHSRUWLWWRWKHDSSURSULDWHVWDWHKHDOWKDJHQF\.,IWKHKHDOWKFDUH
SURIHVVLRQDOLVLQRQHRIWKHVWDWHVWKDWPDQGDWHWKHVHUHSRUWVWKDQVKHVKRXOGVHQG
WKHUHSRUWWRWKHDSSURSULDWHVWDWHKHDOWKDJHQF\.
0RUH LQIRUPDWLRQ DERXW VWDWHVSHFL¿F UHSRUWLQJ UHTXLUHPHQWV FDQ EH IRXQG DW
http://www.migrantclinician.org/exposurereportingmap. 7KHKHDOWKFDUHSURIHVVLRQDO
FDQQRWLI\WKHORFDOSRLVRQFRQWUROFHQWHU 3&& E\FDOOLQJ  2221222.
7KH1DWLRQDO,QVWLWXWHIRU2FFXSDWLRQDO6DIHW\DQG+HDOWK 1,26+ &HQWHUVIRU
'LVHDVH &RQWURO DQG 3UHYHQWLRQ &'&  DQG (3$ VXSSRUW VXUYHLOODQFH IRU SHVWLFLGH
UHODWHGLOOQHVVDQGLQMXU\WKURXJKWKH6(16253HVWLFLGHVSURJUDPWKDWDJJUHJDWHVSHVWL
FLGHLQFLGHQWGDWDIURP11VWDWHV &DOLIRUQLD)ORULGD,RZD/RXLVLDQD0LFKLJDQ1HZ
0H[LFR1HZ<RUN1RUWK&DUROLQD2UHJRQ7H[DVDQG:DVKLQJWRQ DQGKDVDQRFFX
SDWLRQDOIRFXV.7KH&DOLIRUQLD'HSDUWPHQWRI3HVWLFLGH5HJXODWLRQ '35 PDLQWDLQVWKH

15
CHAPTER 2
Making the Diagnosis
3HVWLFLGH,QFLGHQW6XUYHLOODQFH6\VWHP 3,63 .7KHVHVXUYHLOODQFHV\VWHPVFROOHFWFDVH
UHSRUWVRQSHVWLFLGHUHODWHGLOOQHVVHVDQGLQMXULHVIURPFOLQLFLDQVDQGRWKHUVRXUFHV e.g.,
SRLVRQFRQWUROFHQWHUVZRUNHUV¶FRPSHQVDWLRQDJHQFLHVDQGVWDWHDJHQFLHVWKDWUHJXODWH
SHVWLFLGHV FRQGXFWVHOHFWHGLQWHUYLHZV¿HOGLQYHVWLJDWLRQVDQGUHVHDUFKSURMHFWVDQG
IXQFWLRQDVDUHVRXUFHIRUSHVWLFLGHLQIRUPDWLRQZLWKLQWKHLUVWDWH.
7KHLPSDFWVRIWKHVHVXUYHLOODQFHSURJUDPVH[WHQGEH\RQGWKHSDUWLFLSDQWVWDWHV
E\ LGHQWLI\LQJ HPHUJLQJ SHVWLFLGH H[SRVXUH LVVXHV WKDW VWHHU LQWHUYHQWLRQ HIIRUWV WR
SUHYHQWIXWXUHLQFLGHQWVZLWKVLPLODUH[SRVXUHVFHQDULRVQDWLRQZLGH.+RZHYHUWKHUH
UHPDLQV D QHHG IRU V\VWHPDWLF UHSRUWLQJ RI SHVWLFLGH SRLVRQLQJV LQ DOO VWDWHV LQWR D
FHQWUDO DJHQF\ LQ RUGHU WR FRPSLOH DFFXUDWH VWDWLVWLFV RQ WKH IUHTXHQF\ DQG FLUFXP
VWDQFHVRISRLVRQLQJDQGIDFLOLWDWHHIIRUWVWROLPLWWKHVHRFFXUUHQFHV.

b. Contact Pesticide State Lead Agency


%HIRUH VHQGLQJ WKH SDWLHQW V  KRPH FDOO WKH DSSURSULDWH (3$UHFRJQL]HG SHVWLFLGH
6WDWH /HDG$JHQF\ 6/$  ZKLFK FDQ LQYHVWLJDWH SHVWLFLGH SRLVRQLQJ LQFLGHQWV. 7R
¿QG\RXU6/$FRQWDFWJRWRKWWSDDSFRRUJRI¿FLDOVKWPO
7KH 6/$ ZLOO KHOS GHWHUPLQH LI WKHUH ZDV DQ\ YLRODWLRQ RI WKH $JULFXOWXUDO
:RUNHU3URWHFWLRQ6WDQGDUG.,WFDQDOVRWHOO\RXLIDGGLWLRQDODFWLRQRULQIRUPDWLRQLV
QHHGHG.

9. Discuss Workers’ Compensation with the Patient


,IWKHFDVHLQYROYHVDQRFFXSDWLRQDOH[SRVXUHHDFKSDWLHQW¶VFKDUWVKRXOGGRFXPHQWLW
DVVXFK.$ZRUNHUV¶FRPSHQVDWLRQUHSRUWPXVWEHFRPSOHWHGIRUHDFKH[SRVHGZRUNHU.
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PXVWGRFXPHQWHYLGHQFHRIWKHH[SRVXUHDQGWKHLOOQHVVDQGFRQFOXGHWKDWLWLVPRUH
OLNHO\ WKDQ QRW WKDW WKH LOOQHVV ZDV FDXVHG RU DJJUDYDWHG E\ D ZRUNSODFH SHVWLFLGH
H[SRVXUH.7KHOHJDOVWDQGDUGIRUDZRUNHUV¶FRPSHQVDWLRQFDVHLVWKDW there must be
a “preponderance of evidence” that the disease is work related.$SUHSRQGHUDQFH
RIHYLGHQFHLVGH¿QHGDVPHDQLQJWKDWLWLVPRUHOLNHO\WKDQQRW i.e.,JUHDWHUWKDQ
SUREDELOLW\  WKDW WKH SRLVRQLQJ ZDV FDXVHG RU DJJUDYDWHG E\ D ZRUNSODFH SHVWLFLGH
H[SRVXUH.
:RUNHUV¶ FRPSHQVDWLRQ ODZV H[LVW LQ DOO VWDWHV EXW EHQH¿W OHYHOV YDU\ DFURVV
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ZRUNHUV¶ FRPSHQVDWLRQ WKH ZRUNHU LV UHVSRQVLEOH IRU SURYLQJ WKDW KLVKHU GLVHDVH
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PDQ\DFXWHSHVWLFLGHSRLVRQLQJFDVHVZKHUHWKHLOOQHVVLVFRQVLVWHQWZLWKWKHNQRZQ
WR[LFRORJ\RIWKHSHVWLFLGHZKHUHWKHUHLVREMHFWLYHHYLGHQFHWKDWWKHSDWLHQWH[SH
ULHQFHG D SHVWLFLGH H[SRVXUH DQG ZKHUH WKH GRVH ZDV VXI¿FLHQW WR SURGXFH LOOQHVV.
&RVWO\FODLPVVXFKDVGHDWKFODLPVRUFODLPVLQYROYLQJSHUPDQHQWWRWDOGLVDELOLW\DUH
RIWHQFRQWHVWHGE\WKHZRUNHUV¶FRPSHQVDWLRQLQVXUDQFHFRPSDQ\.7KHSURSRUWLRQRI
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ZKHQWKHSRLVRQLQJVLJQVDQGV\PSWRPVUHVHPEOHDFRPPRQUHVSLUDWRU\RUJDVWURLQ
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)LQDOO\FOLQLFLDQVVKRXOGEHDZDUHWKDWUHSRUWLQJDZRUNHUV¶FRPSHQVDWLRQFDVHFDQ
KDYHVXEVWDQWLDOGHOHWHULRXVLPSOLFDWLRQVIRUWKHZRUNHUEHLQJHYDOXDWHG e.g.MREORVV
RUGLVFLSOLQDU\DFWLRQ .

16
CHAPTER 2
Making the Diagnosis
SPECIAL CONCERNS
Ethical Considerations Steps in Investigating
(WKLFDOJXLGHOLQHVDQGFRGHVRIFRQGXFWKDYHEHHQHVWDEOLVKHGWKDWFDQJXLGHKHDOWK a Disease Outbreak
FDUHSURIHVVLRQDOVZKRDUHGHDOLQJZLWKGLOHPPDVLQYROYLQJSHVWLFLGHSRLVRQLQJ.
Con¿rm diagnosis of initial
7KUHHIXQGDPHQWDOYDOXHVXQGHUSLQWKHVHJXLGHOLQHVDQGFRGHVRIFRQGXFW 1 LWLV
case reports (the “index”
WKHGXW\RIWKHKHDOWKFDUHSURIHVVLRQDOWRGRJRRGIRUWKHSDWLHQWDQGWRSODFHWKH
cases)
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WKHEHVWMXGJHRIKLVRUKHURZQEHVWLQWHUHVWVDQG  VRFLDOMXVWLFHSURPRWLRQRID Identify other unrecognized
IDLUDQGHTXLWDEOHGLVWULEXWLRQRI¿QLWHKHDOWKUHVRXUFHV.$PRQJWKHFRGHVRIHWKLFV cases
PRVW UHOHYDQW WR WKH UHDOP RI SHVWLFLGH SRLVRQLQJ LV WKH QHHG WR NHHS FRQ¿GHQWLDO
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WKH UHTXHVW RI WKH LQGLYLGXDO RU ZKHQ WKHUH LV UHDVRQDEOH FRQFHUQ DERXW SRWHQWLDO person, place, and time
HQGDQJHUPHQWRIWKLUGSDUWLHV.´ characteristics (e.g., age,
,QYHVWLJDWLRQ RI D VXVSHFWHG RFFXSDWLRQDO SHVWLFLGH LOOQHVV PD\ QHFHVVLWDWH race, ethnicity, gender and
REWDLQLQJIXUWKHULQIRUPDWLRQIURPWKHZRUNVLWHPDQDJHURURZQHU.$Q\FRQWDFWZLWK location within a company or
WKHZRUNVLWHVKRXOGEHWDNHQLQFRQVXOWDWLRQZLWKWKHSDWLHQWEHFDXVHRIWKHSRWHQWLDO a neighborhood, timeline of
IRUUHWDOLDWRU\DFWLRQVDJDLQVWWKHSDWLHQW VXFKDVMREORVVRURWKHUGLVFLSOLQDU\DFWLRQ . exposure and health events)
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Create plot of case
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SHVWLFLGHH[SRVXUH.7KHGLVFRYHU\RISHVWLFLGHFRQWDPLQDWLRQLQDUHVLGHQFHVFKRRO Determine if a dose-
FKLOGFDUHVHWWLQJIRRGSURGXFWRURWKHUHQYLURQPHQWDOVLWHRUSURGXFWFDQKDYHSXEOLF response relationship
KHDOWK ¿QDQFLDO DQG OHJDO FRQVHTXHQFHV IRU WKH SDWLHQW DQG RWKHU LQGLYLGXDOV e.g., exists (i.e., more severe
EXLOGLQJRZQHUVFKRROGLVWULFWIRRGSURGXFHU .,WLVSUXGHQWWRGLVFXVVWKHVHSRWHQ clinical case presentation
WLDODGYHUVHFRQVHTXHQFHVDQGIROORZXSRSWLRQVZLWKWKHSDWLHQWEHIRUHSXUVXLQJDQ for individuals with higher
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GHSDUWPHQWFDQUHTXHVWDVVLVWDQFHIURPWKH&HQWHUVIRU'LVHDVH&RQWURODQG3UHYHQ (divide number of incident
WLRQ.,QVXFKDVLWXDWLRQHYHQLIWKHLQLWLDOFDVHSDWLHQWREMHFWVWRGLVFORVLQJWKHSHVWL cases by number of exposed
FLGHKD]DUGWRSXEOLFKHDOWKDXWKRULWLHVVWDWHUHSRUWLQJUHTXLUHPHQWVDQGRYHUULGLQJ individuals and multiply by
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IURP&KLOH.%RWKZRUNHUVKDGSURIRXQGQHXURORJLFV\PSWRPVDQGHOHYDWHGVHUXP

17
CHAPTER 2
Making the Diagnosis
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18
CHAPTER 2
Making the Diagnosis
organization of a pesticide label is illustrated in the front panel schematic below and
the back panel schematic on the following page.
Note that for some products with multiple uses (typically agricultural products)
Items Required on
or products with very small containers, EPA allows some information, such as direc- Pesticide Labels
tions for use or worker protection requirements, to be contained in an accompanying
Product name
ERRNOHW UDWKHU WKDQ DI¿[HG RQ WKH FRQWDLQHU 7KH ERRNOHW LV SDUW RI WKH OHJDO ODEHO
ZKLFKLVUHYLHZHGDQGDSSURYHGE\(3$7KHPRVWLPSRUWDQWVDIHW\UHODWHGHOHPHQWV Manufacturer name and
of the label, such as the signal word, ingredients, hazard statements, treatment state- address
ment and EPA registration number, must be on the container itself. EPA registration number
7KH(3$UHJLVWUDWLRQQXPEHULVYHU\XVHIXOZKHQFRQWDFWLQJ(3$IRULQIRUPD-
Active ingredients
tion or when calling the National Pesticide Information Center hotline (see page 24).
Pesticide product labels may differ from one state to another based on marketing or Precautionary statements:
RWKHU DUHDVSHFL¿F FRQVLGHUDWLRQV $OVR GLIIHUHQW IRUPXODWLRQV RI WKH VDPH DFWLYH Human hazard signal
LQJUHGLHQWV PD\ UHVXOW LQ GLIIHUHQW ODEHO LQIRUPDWLRQ 7KH SHVWLFLGH ODEHO JHQHUDOO\ words “Danger” (most
lists information only for active ingredients (not for inert/other components) and rarely hazardous), “Warning,”
and “Caution” (least
hazardous)
Front Panel “Poison” and symbol, if
Organization RESTRICTED USE PESTICIDE applicable
This diagram illustrates the order in Child hazard warning
which front panel label parts usually Due to (insert reason)
appear. Note that not all of the Statement of practical
For retail sale to and use only by Certified
elements must appear on every label. Applicators or persons under their direct treatment (signs and
1. Restricted use pesticide supervision and only for those uses covered by symptoms of poisoning,
the Certified Applicator’s certification.
statement (if applicable) ¿rst aid, antidotes and
2. Product name, brand or note to physicians in the
trademark PRODUCT NAME event of a poisoning)
3. Ingredient statement ACTIVE INGREDIENT(S) ........................ 90.00% Hazards to humans and
(may appear on back OTHER INGREDIENT(S) ........................ 10.00%
domestic animals
panel if inadequate space TOTAL ................................................... 100.00%
on front panel) This product contains XX lbs of [a.i.] per gallon. Environmental hazards
4. EPA registration number EPA Reg. No. XXX-XX Physical or chemical
hazards
5. Child hazard warning Product Information (what product is used for)
statement (if applicable) KEEP OUT OF REACH OF CHILDREN Directions for use
6. Signal word (if SIGNAL WORD Net contents
(ENGLISH/SPANISH)
applicable); skull and EPA establishment number
crossbones symbol and Poison
the word “Poison” (if
applicable)  Worker Protection Standard
(WPS) designation,
Si usted no entiende la etiqueta, busque a alguien para que se la
explique a usted en detalle. (If you do not understand the label,
including restricted entry
find someone to explain it to you in detail.)
interval and personal
7. First aid statement FIRST AID protection equipment
(may appear on back 1 /%%(/ 1 '"% required (agricultural
1 ('$#' 1 #'0+
panel if there is a note &#'*,(".%%/#,"0(-/"' products only) (see WPS
indicating this on calling emergency phone number or going description on page 21)
front panel) for treatment. Emergency phone number.
Note to Physician:

SEE OTHER PANEL FOR


PRECAUTIONARY STATEMENTS

8. Net contents/net weight Net Contents ___________

19
CHAPTER 2
Making the Diagnosis
contains information on chronic health effects (e.g., cancer and neurologic, reproduc-
tive and respiratory diseases). Although further information is often needed, pesticide
ODEHOV DQG ODEHOLQJ VKRXOG EH FRQVLGHUHG DV WKH ¿UVW VWHS LQ LGHQWLI\LQJ DQG XQGHU-
VWDQGLQJWKHKHDOWKHIIHFWVRIDJLYHQSHVWLFLGH7KH$JULFXOWXUDO:RUNHU3URWHFWLRQ
Standard provides the legal basis for the healthcare provider(s) to obtain from the
HPSOR\HUWKHQDPHRIWKHSHVWLFLGHSURGXFWWRZKLFKWKHSDWLHQWZDVH[SRVHG:KHQ
UHTXHVWLQJWKLVLQIRUPDWLRQWKHFOLQLFLDQVKRXOGNHHSWKHSDWLHQW¶VQDPHFRQ¿GHQWLDO
whenever possible.

Back Panel PRECAUTIONARY STATEMENTS


Organization
This diagram illustrates the HAZARDS TO HUMANS AND
order in which back panel DOMESTIC ANIMALS
label (or labeling booklet)
parts usually appear.
Signal Word
Note that not all of these Avoid contact with skin, eyes or clothing. Wash thoroughly
with soap and water after handling and before eating,
elements must appear on drinking, chewing gum, using tobacco or using the toilet.
every label. For products Causes moderate eye irritation. Wear goggles. Harmful if
subject to the Agricultural swallowed. Harmful if absorbed through skin.
Worker Protection Standard
(WPS), the precautionary ENVIRONMENTAL HAZARDS
statements and directions Xxxxx xx xxxxxxx x xxx xxxxxxxxx xxxxx xxxx xxx xxxxx.
for use sections contain
additional pertinent statements. PHYSICAL OR CHEMICAL
HAZARDS
Xxxxx xx xxxxxxx x xxx xxxxxxxxx xxxxx xxxx xxx. Xxxxx
xx xxxxxxx x xxx xxxxxxxxx xxxxx xxxx xxx xxxxx.
1. Precautionary statements

DIRECTIONS FOR USE


It is a violation of Federal law to use this product in a
manner inconsistent with its labeling.

GENERAL INSTRUCTIONS AND


INFORMATION
2. Directions for use
General Information (non-site-specific):
General Precautions and Restrictions
(non-site-specific):
Non-Crop Site/Pest:
Non-Crop Site/Pest:
Crop/Pest:
Crop/Pest:

STORAGE AND DISPOSAL


PESTICIDE STORAGE
3. Storage and disposal
PESTICIDE DISPOSAL
CONTAINER DISPOSAL

4. Warranty statement WARRANTY STATEMENT


(if the registrant chooses Xxxxx xx xxxxxxx x xxx xxxxxxxxx xxxxx xxxx xxx. Xxxxx xx
xxxxxxx x xxx xxxxxxxxx xxxxx xxxx xxx xxxxx. Xxxxx
to include one) xxxxxxx x xxx xxxxxxxxx xxxxx xxxx xxx xxxxx.

20
CHAPTER 2
Making the Diagnosis
Federal Regulatory Agencies

U.S. Environmental Protection Agency

D2I¿FHRI3HVWLFLGH3URJUDPV
Since its formation in 1970, EPA has been the lead agency for the regulation of
pesticide use under the Federal Insecticide, Fungicide, and Rodenticide Act. EPA’s
mandates include the registration of all pesticides used in the United States, setting
restricted entry intervals (i.e., the time interval during which individuals should not
enter or be present in a pesticide-treated area, unless the individual is using appro-
priate personal protective eTuipment , speci¿cation and approval of label information
and setting acceptable food and water tolerance (i.e., residue) levels. In addition, EPA
worNs in partnership with state, territorial, and tribal agencies to implement two ¿eld
programs. First, the certi¿cation and training program for pesticide applicators sets
national standards for those who apply restricted use pesticides, currently just under 1
million people. Second, the Agricultural Worker Protection Standard protects agricul-
tural workers and pesticide handlers from pesticide e[posures through training, ¿eld
posting, requirements for protective equipment and decontamination protocols.
The authority to enforce EPA pesticide regulations is delegated to the states.
Concerns about non-compliance with these regulations can typically be directed
to your pesticide State Lead Agency (SLA). The EPA-recognized pesticide SLA is
typically the state agriculture department but in some states and territories it can be
another state agency (e.g., the state environmental protection agency). To identify
the pesticide SLA in your state, visit the Association of American Pesticide Control
2f¿cials (AAPC2) website at http://aapco.org/. If a worker would like to report a
pesticide violation to the SLA but fears possible retaliatory action by management
(e.g. , job loss or disciplinary action), the worker can make an anonymous call to the
SLA. Note that not all state departments of agriculture have identical regulations. For
instance, only California and Washington State require employers to obtain cholin-
esterase testing of agricultural pesticide handlers who apply pesticides containing
cholinesterase-inhibiting compounds.
For pesticide contamination in water, EPA sets enforceable maximum contain-
ment levels. EPA also works jointly with the Food and Drug Administration (FDA)
and the U.S. Department of Agriculture (USDA) to monitor and regulate pesticide
residues and their metabolites in food and drugs. Tolerance limits are established by
EPA for pesticides and their metabolites in raw agricultural commodities.

E$JULFXOWXUDO:RUNHU3URWHFWLRQ6WDQGDUG :36
Recognizing that agricultural employees needed increased protection from pesti-
cide exposures, EPA promulgated 40 CFR 170, the Agricultural Worker Protection
Standard (WPS). The intent of the regulation is to protect agricultural employees
by eliminating or reducing pesticide exposure, mitigating exposures that occur and
informing agricultural employees about the hazards of pesticides. The WPS applies
to two types of employees in the farm, greenhouse, nursery and forest industries:
(1) agricultural pesticide handlers (mixer, loader, applicator, equipment cleaner
or repair person, and Àagger) and (2) ¿eld workers performing hand labor tasks
(cultivator or harvester). The regulation does not cover agricultural employees in
livestock production. The WPS includes requirements that agricultural employers
notify employees about pesticide applications in advance, offer basic pesticide
safety training, provide necessary personal protective equipment for direct work

21
CHAPTER 2
Making the Diagnosis
with pesticides and observe restricted entry interval (REI) times. Of special interest
to healthcare providers, the WPS also requires agricultural employers to:

‡ Post an emergency medical facility address and phone number in a


central location.
‡ Arrange immediate transport from the agricultural establishment to a
medical facility for ¿eld workers or pesticide handlers who become ill
or injured after an acute work-related pesticide exposure.
‡ Provide the exposed worker or handler and medical personnel with the
pesticide product name, EPA registration number, active ingredient(s),
medical information from the label, a description of how the pesticide
was used, and any other relevant exposure information.

2FFXSDWLRQDO6DIHW\DQG+HDOWK$GPLQLVWUDWLRQ
The Occupational Safety and Health Administration (OSHA) plays a less substantial
role than EPA in pesticide regulation. Whereas EPA has authority over pesticides in the
home, environment and workplace, OSHA has authority only in the workplace. Like
EPA, OSHA allows states to enforce federal OSHA regulations or their own adaption
of the federal regulations (which must be approved by federal OSHA and be at least
as stringent as the federal regulations). A total of 2 states, Puerto Rico and the 9irgin
Islands have such OSHA-approved state plans. In the other 2 states, regulations are
enforced by federal OSHA.
OSHA has fewer responsibilities in agricultural workplaces compared to non-
agricultural workplaces. For example, small farms (employing 10 or fewer non-family
workers and having no temporary labor camps within the last 12 months) are exempt
from enforcement of all OSHA rules, regulations and standards (http://www.osha.
gov/pls/oshaweb/owadisp.show_document?p_table=DIRECTIVES&p_id=1519). The
only exceptions to this are in California, Oregon and Washington, where the OSHA-
approved state plans enforce OSHA rules, regulations and standards on farms of all
sizes. OSHA is authorized to inspect farms with 11 or more employees but generally
defers to EPA-delegated state agencies for enforcement of all pesticide-related activi-
ties in crop-based agriculture. The pesticide enforcement activities deferred to these
EPA-delegated state agencies include the Worker Protection Standard, compliance
with language on the pesticide label and compliance with pesticide registration, clas-
si¿cation and labeling requirements.
In the non-agricultural setting, OSHA has greater jurisdiction over workplace
pesticide exposures. All workers involved in pesticide manufacturing are covered by
OSHA, which has established permissible exposure levels for selected pesticides (e.g.,
captan, carbaryl, carbofuran, chlorpyrifos, chloropicrin, 2,4-D, diazinon, propoxur
and pyrethrum). Similar to the option of anonymous reporting of suspected pesticide
exposures or violations in agriculture to EPA or the State Lead Agency, a worker in a
non-agricultural setting who fears possible retaliatory action can anonymously report
a suspected pesticide violation to OSHA.

22
CHAPTER 2
Making the Diagnosis
Pesticide Information Resources
(3$2I¿FHRI3HVWLFLGH3URJUDPV
EPA’s Of¿ce of Pesticide Programs (OPP) is responsible for registering pesticide
products and regulating their use.

D 3HVWLFLGH :RUNHU 6DIHW\ 3URJUDP Within OPP, the Pesticide Worker Safety
Program conducts a variety of regulatory and outreach activities aimed at protecting the
pesticide workforce, including agricultural workers, handlers and pesticide applicators.
EPA/OPP also leads the National Strategies for Health Care Providers: Pesticides Initiative
with the goal of improving the training of healthcare providers in the recognition,
diagnosis, treatment and prevention of pesticide poisonings among those who work with
pesticides. See Appendix B, Key Competencies for Clinicians to learn more. Pesticide
safety materials developed through the Pesticide Worker Safety Program, including this
manual, can be ordered online at no charge from the National Agricultural Center at:
http://www.epa.gov/agriculture/awor.html
Further information on Pesticide Worker Safety Program activities is available at:
http://www2.epa.gov/pesticide-worker-safety

E3HVWLFLGH&KHPLFDO6HDUFKPesticide Chemical Search was created by EPA/OPP to


allow users to easily ¿nd information such as Reregistration Eligibility Decisions (REDs),
factsheets, science reviews and regulatory actions on the chemical of interest. The site is
searchable by chemical name or active ingredient (CAS number or pc code) and is located on
the EPA Pesticides website at http://iaspub.epa.gov/apex/pesticides/f?p=chemicalsearch:1
or click on the Chemical Search icon on the EPA Pesticides homepage.

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&HQWHUVIRU'LVHDVH&RQWURODQG3UHYHQWLRQ
NIOSH is the federal agency responsible for conducting research on occupational
disease and injury. NIOSH investigates potentially hazardous working conditions
upon request, makes recommendations on preventing workplace disease and injury,
and provides training to occupational safety and health professionals.
(800) 356-4674 or http://www.cdc.gov/niosh/homepage.html

D &HQWHUV IRU $JULFXOWXUDO 'LVHDVH DQG ,QMXU\ 5HVHDUFK (GXFDWLRQ DQG
Prevention. NIOSH has funded eight Agricultural Health and Safety Centers throughout
the country. These centers conduct research and develop intervention programs aimed
at preventing occupational disease and injury of agricultural workers and their families.
http://www.cdc.gov/niosh/agctrhom.html

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3HVWLFLGHVSurveillance for pesticide-related illness and injury is designed to protect
the public by determining the magnitude and underlying causes of over-exposure to
pesticides. Surveillance also serves as an early warning system of any harmful effects not
detected by manufacturer testing of pesticides. The NIOSH Centers for Disease Control
and Prevention (CDC) and EPA support surveillance for pesticide-related illness and
injury through the SENSOR-Pesticides program. In 2012, 11 states were participating in
the SENSOR-Pesticides program. The success of these state-based pesticide poisoning
surveillance systems relies on healthcare providers to report cases of suspected pesticide
poisoning. Further information about SENSOR-Pesticides is available at the website.
http://www.cdc.gov/niosh/topics/pesticides/

23
CHAPTER 2
Making the Diagnosis
1DWLRQDO3HVWLFLGH,QIRUPDWLRQ&HQWHU
The National Pesticide Information Center (NPIC) is based at Oregon State University
and is cooperatively sponsored by the university and EPA. NPIC serves as a source
of objective, science-based pesticide information on a wide range of pesticide-related
topics, such as recognition and management of pesticide poisonings, safety informa-
tion, health and environmental effects, referrals for investigation of pesticide inci-
dents, emergency treatment for both humans and animals and cleanup and disposal
procedures. NPIC also provides a rapid response in the form of skilled technical assis-
tance to persons suspected of being adversely affected by pesticide exposures. Highly
quali¿ed pesticide specialists and a physician with extensive experience in pesticide
toxicology provide and deliver appropriate information to all inquiries. A toll-free tele-
phone service provides pesticide information in both English and Spanish to callers in
the continental United States, Puerto Rico and the 9irgin Islands. Additionally, pesti-
cide questions and comments can be sent to an email address. The website (in both
English and Spanish) has links to other sites and databases for further information.
(800) 858-7378
(Hotline hours of operation: 6:30 am – 3:30 pm PST,
Monday through Friday, except holidays)
http://www.npic.orst.edu

0LJUDQW&OLQLFLDQV1HWZRUN
The Migrant Clinicians Network strengthens healthcare services and infrastructure for
migrants and other mobile poor through training and technical assistance to clinicians
and communities. As a partner to EPA’s Health Care Provider Initiative, MCN assists
primary care providers in recognizing, managing and preventing pesticide exposures and
provides critically needed referral to occupational and environmental specialists. MCN’s
pesticide website provides clinical tools and resources and patient educational materials
as part of its comprehensive pesticide exposure prevention and response efforts.
(512) 327-2017 or http://www.migrantclinician.org
http://www.migrantclinician.org/clinical_topics/pesticides.html
http://www.migrantclinician.org/clinical_topics/environmental-
and-occupational-health.html

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The American Association of Poison Control Centers (AAPCC) is a non-pro¿t,
national organization founded in 19. AAPCC represents the poison control centers
of the United States and the interests of poison prevention and treatment of poisoning.

Emergencies
Local Poison
Control
1-800-222-1222

(800) 222-1212
(local Poison Control Center access)
http://www.aapcc.org

24
CHAPTER 2
Making the Diagnosis
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The Association of Occupational and Environmental Clinics (AOEC) is a network of
more than 0 clinics and more than 20 specialists that facilitates the prevention and
treatment of occupational and environmental illnesses and injuries.

(202) 347-4976 or http://www.aoec.org

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The Farmworker Justice Fund can provide an appropriate referral to a network of legal
services and nonpro¿t groups which represent farmworkers for free.
(202) 776-1757 or http://www.farmworkerjustice.org

Pesticide Information Databases

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3HVWLFLGH,OOQHVV6XUYHLOODQFH3URJUDP
Since 1971, California law has required doctors to report any disease or condition that
they know or have reason to believe resulted from pesticide exposure. The California
Department of Pesticide Regulation (DPR) collects these reports in its Pesticide Illness
Surveillance Program. To supplement physician reporting, DPR cooperates with the
California Department of Public Health and California Department of Industrial Rela-
tions to search workers’ compensation documents for pesticide-related disability. More
recently, DPR has contracted with the California Poison Control System to help doctors
ful¿ll their responsibility to report. As of 2011, a law requires clinical laboratories to
send DPR the results of cholinesterase tests done to evaluate pesticide exposure. County
agricultural commissioners (CACs) investigate every case identi¿ed and send reports of
their ¿ndings to DPR. Scientists of the Pesticide Illness Surveillance Program review,
evaluate and abstract all reports received from CACs and are working to integrate cholin-
esterase reports. Data from this program and others (including pesticide use, product
label, enforcement, school IPM and more) can be retrieved from the website.
http://www.cdpr.ca.gov/dprdatabase.htm

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The National Pesticide Information Retrieval System (NPIRS) receives funding from
EPA to maintain a pesticide information database. NPIRS provides publicly available
registration information on approximately 90,000 EPA-registered pesticides. The data
include: product number and name, company number and name, registration date,
cancellation date and reason, existing stocks date and product manager name and
phone number. NPIRS is administered by the Center for Environmental and Regula-
tory Information Systems at Purdue University in West Lafayette, Indiana.
http://ppis.ceris.purdue.edu/

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The Agency for Toxic Substances and Disease Registry (ATSDR), part of the Depart-
ment of Human Health and Services, publishes fact sheets and information on pesti-
cides and other toxic substances.
http://www.atsdr.cdc.gov/

25
CHAPTER 2
Making the Diagnosis

Data Collection on an Acute Pesticide Exposed Patient

When patients present with an identi¿ed pesticide poisoning, the following


data collection format has been recommended to guide the clinician on the
appropriate information to obtain as well as an evaluation of appropriate
samples and other materials

1 PT ID: NameAgeSex2ccupation

2 Initial and subsequent symptoms and signs

 Name of pesticide product and active ingredients, their concentration


and EPA registration number

 Date and time when exposure occurred

 How the pesticide was applied, when applied and on what crop or for
what use

 Route(s) of exposure: dermal, ocular, oral, respiratory

 How much of the product was ingested, if ingested

8 Circumstances of exposure ± intentional or accidental, occupational or


non-occupational

 A detailed description of how the exposure happened

10 Treatment already received

a Skin exposure:

i Was affected area washed? If so, when? If not, proceed with


skin decontamination procedures

ii Was any clothing contaminated?

iii If so did they change clothes?

b 2cular exposure:

i Were the eyes irrigated?

ii If so, with what and for how long?

c *I exposure:

i Were any emetics used?

ii Were any absorbents used?

iii Were any home remedies (e.g., water, milk, lemon Muice)
used?

iv Was there any emesis before arrival?

26
CHAPTER 2
Making the Diagnosis

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Materials to be Gathered:

1 A copy of the pesticide label andor a copy of the Material Safety Data
Sheet (MSDS)

2 A copy of the pesticide application record (tank mix, concentration, etc)


if applicable This should be available from the pesticide applicator or
the grower

 10 cc whole blood, anticoagulated with sodium heparin (refrigerate)

  cc plasma anticoagulated with sodium heparin (refrigerate)

 A fresh urine sample (label and freeze)

 Any contaminated clothing, hats, foliage from the site Place in clean
sealable plastic bag label, seal and freeze

 2ther options:

a Fingernail residue If the worker handled the pesticide or materials


with pesticide residue, some pesticide may be lodged under the
¿ngernails Clean under the nails Place in clean sealable plastic
bag, label, seal and freeze

b Saliva sample Some pesticides can be detected in saliva Have the


patient spit repeatedly into a clean glass or plastic container Seal
the container, label and freeze

c Hair sample, if the head was exposed Place in clean sealable


plastic bag, label, seal and freeze

d A skin wipe with ethanol-impregnated swab

i Wipe skin that was contaminated if possible 8se a newly


opened alcohol wipe Wipe an area of skin and if possible
estimate the size of the area wiped and record this on the
sample label Try to focus on an area that is likely to have been
contaminated in the exposure

ii Place wipe in clean sealable plastic bag, label, seal and freeze

*For the pediatric patient, note parents’ occupations and child’s


appearance compared to his/her usual baseline. It is important to ask
if the child is acting normally, if there is an abnormal gait, stumbling or
ataxia; and if the child has experienced excessive sleepiness, irritability
or other personality changes.

Developed by Matthew C. Keifer MD, MPH


National Farm Medicine Center

27
CHAPTER 2
Making the Diagnosis
References

1. Liebman AK, Rowland MM. To ask or not ask: The critical role of the primary care
provider in screening for occupational injuries and exposures. J Public Health Manag
Pract. 2009:1(2):17-.
2. Levy BS, Wegman DH (eds). Occupational and Environmental Health, th ed. Lippincott
Williams and Wilkins, Phila. 200. 47 pp.
. Agency for Toxic Substances and Disease Registry. Case studies in environmental medi-
cine: taking an exposure history. 2008, 2011. Accessed 10/12/12: http://www.atsdr.cdc.
gov/csem/exphistory/docs/exposure_history.pdf.
4. Rowland MM, Liebman AK, Sudakin DL, Keifer MC. Learning Opportunities from the
Reported Incident of Pesticide Poisoning. Streamline. 200, 12():.
. Ashford NA. Workers’ compensation. In: Rom WN, editor. Environmental and Occupa-
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2007. pp 1712-19.
6. ACOEM. The seven ethical principals of occupational and environmental medicine.
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aspx.
7. Blank L, Kimball H, McDonald W, Merino J; ABIM Foundation; ACP Foundation; Euro-
pean Federation of Internal Medicine. Medical professionalism in the new millennium: a
physician charter 1 months later. Ann Intern Med. 200;1:9-41.
. Centers for Disease Control and Prevention. Illnesses associated with exposure to methyl
bromide-fumigated produce ² California, 2010. MMWR. 2011;60:92-26.
9. Brooks SM, *och¿eld M, Herzstein J, et al. Environmental Medicine. St. Louis, MO:
Mosby <earbook. 199.
10. Steenland K. Case Studies in Occupational Epidemiology. New York: Oxford University
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11. Centers for Disease Control and Prevention. HIPAA Privacy Rule and Public Health: Guid-
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http://www.cdc.gov/mmwr/preview/mmwrhtml/m2e411a1.htm.

Other References
Blondell, J. Epidemiology of pesticide poisonings in the United States, with special reference to
occupational cases. Occup Med-C. 1997; 12(2):209-20.
McCauley LA, Lazarev MR, Higgins G, Rothlein J, Muniz J, Ebbert C, et al. Work character-
istics and pesticide exposures among migrant agricultural families: A community based
research approach. Environ Health Perspect. 2001;109:-.
Stanbury M, Anderson H, Rogers P, Bonauto D, Davis L, Materna B, Rosenman K. Guidelines
for Minimum and Comprehensive State-Based Public Health Activities in Occupational
Safety and Health, DHHS Publication No. 200-14. National Institute for Occupational
Safety and Health, Cincinnati, OH. 200. Online at http://www.cdc.gov/niosh/docs/200-
14.

28

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