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What are liver enzymes?

Enzyme is a chemical that accelerates (speeds up) chemical


reactions within the body. There are several enzymes in the liver,
including alanine transaminase (ALT), aspartate transaminase
(AST), alkaline phosphatase (ALP), and gamma-glutamyl
transpeptidase (GGT). Elevated liver enzymes, found with a blood
test, indicate inflamed or injured liver cell

A chart showing the levels of liver enzymes in case of a Increase


and Decrease:

Enzyme Increased Enzyme Decreased Enzyme


( ALT) 1. Increase level affecting other parts of 1. A low level of ALT in the blood
the body. Nevertheless, injury to organs is expected and is normal. Liver
other than the liver, such as the heart and disease is the most common reason
skeletal muscle, can cause elevations of for higher than normal levels
ALT. For example, small increases may of ALT. Very high levels
be seen with skeletal muscle damage of ALT (more than 10 times
or heart attack normal) are usually due to acute
hepatitis, sometimes due to a viral
hepatitis infect
(AST) 1. A high AST level is a sign of liver 1. Low levels of AST in the blood
damage, but it can also mean you have are expected and are normal. Very
damage to another organ that makes it, high levels of AST (more than 10
like your heart or kidney times normal) are usually due to
2. Typically the range for normal AST is acute hepatitis, sometimes due to a
reported between 10 to 40 units per liter viral infection. ... In most types of
and ALT between 7 to 56 units per liter. liver disease, the ALT level is
Mild elevations are generally considered higher than AST and the AST/ALT
to be 2-3 times higher than the normal ratio will be low 
range. In some conditions, these enzymes
can be severely elevated, in the 1000s
rang

) ALP( 1. High levels may also indicate an issue 1. Low levels having lower-than-


related to the bones such as rickets, normal ALP levels in your blood is
Paget's disease, bone cancer, or an rare, but it can indicate
overactive parathyroid gland. In rare malnutrition, which could be caused
cases, high ALP levels can indicate heart by celiac disease or a deficiency in
failure, kidney cancer, other cancer, certain vitamins 
mononucleosis, or bacterial infection
))GGT High levels of GGT in the blood could .1 1.They may also be caused
indicate that the enzyme is leaking out of by alcohol abuse, alcoholic liver
the liver cells and into the blood, disease, or use of drugs that are
suggesting damage to the liver or bile toxic to the liver. A low or normal
ducts. A typical range for GGT levels in GGT test result indicates that it is
adults and children is between 0 and 30 unlikely that you have liver
international units per liter (IU/L) disease or have consumed
any alcohol

2. Some of the conditions that result in cardiovascular disease and .2


increased GGT include:
diabetes, as well as all-cause
 overuse of alcohol. mortality in both men and women,
 chronic viral hepatitis. when GGT concentrations exceeded
 lack of blood flow to the liver.
the lowest 25% of normal
 liver tumor.
 cirrhosis, or scarred liver. .population ranges
 overuse of certain drugs or other
toxins.
 heart failure.
 diabetes

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