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  • H.W Macrolids

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    Rania Hamam
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    Erethromycin, Clarithromycin, Roxthromycin, Azithromycin, and Telithromycin are macrolide antibiotics effective against gram-positive cocci like Streptococcus and gram-negative bacteria like Haemophilus influenzae. They are used to treat respiratory tract infections, pneumonia, pharyngitis, tonsillitis, sinusitis, bronchitis, and soft tissue infections. They have varying degrees of acid stability, ability to cross the blood brain barrier, safety during pregnancy and lactation, and excretion route.

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    Erethromycin, Clarithromycin, Roxthromycin, Azithromycin, and Telithromycin are macrolide antibiotics effective against gram-positive cocci like Streptococcus and gram-negative bacteria like Haemophilus influenzae. They are used to treat respiratory tract infections, pneumonia, pharyngitis, tonsillitis, sinusitis, bronchitis, and soft tissue infections. They have varying degrees of acid stability, ability to cross the blood brain barrier, safety during pregnancy and lactation, and excretion route.

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    © All Rights Reserved
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    7 views1 page

    H.W Macrolids

    Uploaded by

    Rania Hamam
    Erethromycin, Clarithromycin, Roxthromycin, Azithromycin, and Telithromycin are macrolide antibiotics effective against gram-positive cocci like Streptococcus and gram-negative bacteria like Haemophilus influenzae. They are used to treat respiratory tract infections, pneumonia, pharyngitis, tonsillitis, sinusitis, bronchitis, and soft tissue infections. They have varying degrees of acid stability, ability to cross the blood brain barrier, safety during pregnancy and lactation, and excretion route.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 1

    Erethromycin Clarithromycin Roxthromycin Azithromycin Telithr

    G+ve Streptococcus
    aureuse

    G-ve Haemophiluse Limited Limited Effective on L


    influ. G-ve more
    than G+ve

    Uses RTI,soft tissue Pneumonia RTI Staph.aureus Pneu


    inf. Pharyngitis UTI inf.
    Tonsillitis Soft tissue inf. Otitis
    Sinusitis Sinusitis
    Ch.bronchitis Strep throat
    Skin inf. Prevent inf.in
    H.pylori infant

    Gastric
    acid-
    stability

    Cross BBB
    .

    Pregnancy Safe Safe Safe Safe Catego

    Lactation Safe Safe No available Safe No av


    data

    Excretion Bile Bile Bile Bile


    Notes K

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