Professional Documents
Culture Documents
Pharma 100q
Pharma 100q
2.True of metabolism:
A. aims to make the drug more polar and readily excretable***
B. aims to make the drug more effective
C. aims to make the drug stay in the body longer
D. aims to make the drug less toxic
7. Phase of clinical trial that involves “many doctors & many patients”:
A. PHASE I B.PHASE II C.PHASE III*** D.PHASE IV
13. Given orally it causes sedation and also ‘resets the biological clock
being used for the purpose to counter jet lag:
A. nitric oxide B. melatonin*** C. purines D. arachidonic acid
64. The following are drugs with positive inotropic effect, EXCEPT:
A digoxin B. hydrochlorothiazide*** C. amrinone D. dobutamine
65. A 21 year old male sustained a severe head in a car accident and
found to have an elevated intracranial pressure. CT scanning
showed no intracranial hemorrhage. You would start on:
A. amiloride*** B. mannitol C. furosemide D. benzthiazide
77. Most serious toxic reactions to local anesthetics are due to:
A. convulsions from excessive blood levels ***
B. conversion of hemoglobin to methemoglobin
C. its direct effect on the cardiac muscles
D. its toxicity to nerve muscles
79. The clinical use of disulfiram depends on its ability to inhibit this
enzyme:
A. adenylyl cyclase
B. cytochrome P450
C. alcohol dehydrogenase
D. aldehyde dehydrogenase***
88. Successful therapy of congestive heart failure with digoxin will result
in which one of the following?
A. decreased heart rate***
B. increased after load
C. increased renin secretion\increased after load
D. increased sympathetic outflow to the heart
89. Succinylcholine are peripherally acting skeletal muscle relaxants that
are sometimes used to:
A. treat trauma to the spinal cord
B. treat neuromuscular diseases
C. act as adjuncts to general anesthesia***
D. relieve spasms from traumatic injuries
96. The most commonly used antibiotic in topical preparation with a very
low incidence of hypersensitivity reaction:
A. clotrimazole C. griseofulvin
B. bacitracin*** D. cephalexin
97. Which of the following drugs is LEAST likely to be effective in the
treatment of an infection caused by S. aureus?
A. amoxycillin *** C. cefazolin
B. nafocillin D. oxacillin
REFERENCES:
(1)BASIC & CLINICAL PHARMACOLOGY
8TH EDTION
BERTRAM KATZUNG
(2)BOODMAN & GILMAN’S: THE PHARMACOLOGICAL BASIS OF
THERAPEUTICS
10TH EDITION EDITED BY HARMAN & LIMBIRD
REVIEW QUESTIONS
DEPARTMENT OF
PHARMACOLOGY