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Regeneration
Regeneration
The embryo has the capacity to undergo regulative growth when cells or tissues are removed or rearranged.
In the adult, regeneration can replace missing parts by growth and remodeling of somatic tissues.
Newts have a great capacity for regeneration (i.e. regeneration of lens from iris epithelium).
Mammals can regenerate liver & broken bones can mend but not lost limbs.
Two main types of regeneration are:
1) morphoallaxis has little growth and depends upon re-patterning of tissues (as seen in Hydra) and
2) epimorphosis depends upon growth of new and correctly patterned structures.
Morphoallaxis: Hydra grows by loss of cells from its ends and by budding.
Hydra has a hollow tubular body (0.5 cm long), with tentacles surrounding the mouth (hypostome) and, at the
other end, a basal disc (foot).
Hydra has only two germ layers, the ectoderm and the endoderm separated by the basement membrane.
Hydra undergo continuous growth and pattern formation and cells are lost at the tentacle tips and from the basal
disc.
The cells continually change their position and form new structures as they move up and down the body column.
Budding occurs, 2/3 down body axis which develops a head then detaches as a small new Hydra.
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8/20/2019 BIOL3530: Developmental Biology, Regeneration
Plant cuttings can produce complete plants by regenerating all positional values.
email me at bestave@mun.ca
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