Uka Tarsadia University

B.Pharm.
PH3003: Pharmaceutics-I

Semester - 1

EFFECTIVE FROM July-2019

 Uka Tarsadia University
1st Sem B.Pharm.
PHARMACEUTICS-I
(Subject code: PH3003)

Credits: 03: Theory Contact Hours: 45 hrs

Instructional Methods and Pedagogy:

Faculty members shall explain in a class room using black board and multimedia projector
through PowerPoint presentation.

Minimum No. of
Unit No Approx. Weightage %
Contact Hours
Unit 1 7 15.55
Unit 2 8 17.77
Unit 3 7 15.55
Unit 4 8 17.77
Unit 5 6 13.33
Unit 6 9 20.00
Total 45 100 %
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Sr. No. Subject Hours
1st sem 3 hrs/week +
PH3003 Pharmaceutics-I
B.Pharm. 1 hr/week Tutorial
(Theory) 04 Credits
Scope & Objectives:
This course is designed to impart a fundamental knowledge on the preparatory pharmacy
with arts and science of preparing the different conventional dosage forms.
Course outcome:
1. Upon completion of this course the student should be able to:
2. Know the history of profession of pharmacy
3. Understand the basics of different dosage forms, pharmaceutical incompatibilities
and pharmaceutical calculations
4. Understand the professional way of handling the prescription
5. Preparation of various conventional dosage forms
Sr. No. Topic Hours
Unit – I
1 Historical background and development of profession of pharmacy: 7
History of profession of Pharmacy in India in relation to pharmacy
education, industry and organization, Pharmacy as a career,
Pharmacopoeias: Introduction to IP, BP, USP and Extra
Pharmacopoeia.
Dosage forms: Introduction to dosage forms, classification and
definitions
Prescription: Definition, Parts of prescription, handling of
Prescription and Errors in prescription.
Unit – II
2 Posology: Definition, Factors affecting posology. Pediatric dose 8
calculations based on age, body weight and body surface area.
Pharmaceutical calculations: Weights and measures – Imperial &
Metric system, Calculations involving percentage solutions,
alligation, proof spirit and isotonic solutions based on freezing point
and molecular weight.
Unit – III
3 Liquid dosage forms: Advantages and disadvantages of liquid 7
dosage forms.
Excipients used in formulation of liquid dosage forms. Solubility
enhancement techniques.
Monophasic liquids: Definitions and preparations of Gargles,
Mouthwashes, Throat Paint, Eardrops, Nasal drops, Enemas, Syrups,
Elixirs, Liniments and Lotions.
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Unit – IV
4 Biphasic liquids: 8
Suspensions: Definition, advantages and disadvantages,
classifications, Preparation of suspensions; Flocculated and
Deflocculated suspension & stability problems and methods to
overcome.
Emulsions: Definition, classification, emulsifying agent, test for the
identification of type of Emulsion, Methods of preparation &
stability problems and methods to overcome.
Unit – V
5 Powders: Definition, classification, advantages and disadvantages, 6
Simple & compound powders – official preparations, dusting
powders, effervescent, efflorescent and hygroscopic powders,
eutectic mixtures. Geometric dilutions.
Suppositories: Definition, types, advantages and disadvantages,
types of bases, methods of preparations. Displacement value & its
calculations, evaluation of suppositories.
Unit – VI
6 Semisolid dosage forms: Definitions, classification, mechanisms and 9
factors influencing dermal penetration of drugs. Preparation of
ointments, pastes, creams and gels. Excipients used in semi-solid
dosage forms. Evaluation of semi-solid dosage forms
Pharmaceutical incompatibilities: Definition, classification,
physical, chemical and therapeutic incompatibilities with examples.

Sr. No. PH3003 Pharmaceutics-I 4hrs/week

(Practical) 2 Credits
01 Syrups
a) Syrup IP’66
b) Compound syrup of Ferrous Phosphate BPC’68
02 Elixirs
a) Piperazine citrate elixir
b) Paracetamol pediatric elixir
03 Linctus
a) Terpin Hydrate Linctus IP’66
b) Iodine Throat Paint (Mandles Paint)
04 Solutions
a) Strong solution of ammonium acetate b) Cresol with soap
solution
c) Lugol’s solution
05 Suspensions
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a) Calamine lotion
b) Magnesium Hydroxide mixture
c) Aluminimum Hydroxide gel
06 Emulsions
a) Turpentine Liniment
b) Liquid paraffin emulsion
07 Powders and Granules
a) ORS powder (WHO)
b) Effervescent granules
c)Dusting powder
d)Divided powders
08 Suppositories
a) Glycero gelatin suppository
b) Coca butter suppository
c) Zinc Oxide suppository
09 Semisolids
a) Sulphur ointment
b) Non staining-iodine ointment with methyl salicylate
c) Carbopol gel
10 Gargles and Mouthwashes
a) Iodine gargle
b) Chlorhexidine mouthwash
Text books:
1. Practical handbook of Pharmaceutics (Dispensing Pharmacy); Sanmathi BS; Books
India Publication.
2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS
publishers, New Delhi.
Reference books:
3. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott
Williams and Walkins, New Delhi.
4. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS
publishers, New Delhi.
5. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill
Livingstone, Edinburgh.
6. Indian pharmacopoeia.
7. British pharmacopoeia.
8. Lachmann. Theory and Practice of Industrial Pharmacy,Lea& Febiger Publisher, The
University of Michigan.
9. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott
Williams, New Delhi.
10. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
11. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society,
Elsevier Health Sciences, USA.
12. Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC,
New York.
13. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel
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Dekker, INC, New York.
14. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and
Suspensions, Marcel Dekker, INC, New York.