Note: Any up-dates are to be completed in different color ink.
k. The student is expected to document all meds the client is currently receiving.
MEDICATION NAME
GENERIC/TRADE INDICATION/ ACTION
CLASSIFICATION
(PHARM) AND
PREGNANCY
CATEGORY
Treatment of entrococcal
Aminoglycosides infections, syergy with
(Gentamyacim) penicillin required, Tx for
serious gram-negative
Ani-infectives bacillary infections and
infections caused by
Preg. Cat. C staphylococci when
penicillin or other less toxic
Davis Drug Guide dugs are contraindicated.
for NSG Page 140- Gentamicin IV prevention
145 of in effective endcarditis.
Mosby’s Drug Nsg Steptomycin with
Card 356 gentamicin as combination
with other agents in the
management of serious
enterococcal infections.
Inhibits protein synthesis in
bacteria a level of 30S
ribonsome. Most
aminoglycosides notable for
activity against
Staphylococcus, P.
aeruginosa, Klebsiella
pnuemoniae, E.coli,
Proteus, Serratia,
acineobarter,
DOSE, ROUTE, TIMES EFFECTS
DOSGE FOOD/DRUG SIDE EFFECTS PREGANCY FETUS NURSING CONSIDERATIONS
RANGE INTERACTIONS AND/OR NEONATE
(include therapeutic
dose calculation)
IM, IV Adults and Inactived by penicillins Burning, Aminoglycosides Assess patient for infection (vital
Children 5mg/kg q and cephalosporins when inflammation, itching Can cross the signs, wound appearance, sputum,
8hr or 7.5 mg/kg q 12 coadministered to patient lacrimation, redness, placenta and may be urine, stool, WBC) beginning of and
hr (not to exceed with renal insufficiency. irritation after toxic to the fetus. throughout therapy. Obtain
1.5g/day) Possible respiratory application, Infection, risk for. specimens for culture and sensitivity
IM, IV Adults Renal paralysis after inhalation development of before initiating therapy. First dose
impairment - anesthetics or ocular may be given before receiving
Loading dose neuromuscular blocking hypersensitivity and results. Assess patient for signs of
10mg/kg further agents. Increase incidence other local adverse super infection (fever, upper
dosing based on of ototoxicity with loop rxs. Possible growth respiratory infection, vaginal itching
blood level diuretics, nephrotoxicity of non-susceptible or discharge, increasing malaise,
monitoring and renal with other nephrotoxic organisms, viral diarrhea) Evaluate eighth cranial
function assessment. drugs. Neomycin may infection. Ataxia, nerve function by andiometry before
M.avium complex increase anticoagulant vertigo, ototoxicity, and throughout therapy. Hearing
7.5-15mg/kg/day effects of warfarin or (vestibular and loss is usually in the high –
divided q12-24hr. decrease absorption of cochler), frequency range. Prompt
IM, IV Neonates digoxin and methotrexate. Nephrotoxicity. recognition and intervention are
loading dose 10mg/kg Neomycin-diarrhea, essential in preventing permanent
Maintenance dose nausea, vomiting, damage. Also monitor for vestibular
7.5mg/kg q 12hr. Hypomagnesemia, dysfunction (vertigo, ataxia, nausea,
muscle paralysis vomiting) Eighth cranial nerve
(high parenteral dysfunction is associated with
doses). Increased persistently elevated peak
neuromuscular aminoglycosides if tinnitus or
blockade. Apnea and subjective hearing loss occurs.
hypersensitivity Monitor intake & output and daily
reaction. weight to assess hydration status
and renal function.
PHARM