1. Flow and baseline data 90 HSP patients were randomized √ into 3 groups (NMES = 36, TENS = 36, control group = 18). 81 patients completed all evaluations after 4 weeks of √ treatment. 62 patients completed all evaluations at 8 weeks. The percentage of subjects that completed the study is 44%. 54 patients were excluded: Severe cognitive impairment (MMSE < 24) √ Suffered from cerebrovascular disease and left dysfunction Implantation of pacemakers Any other disorder that affects neuromuscular function 37 patients were excluded: Unwilling to sign informed consent An unstable medical condition A comparison of the demographic characteristics NRS, AROM/PROM, FMA, MAS, BI, and SSQOLS scores did not exhibit statistically significant √ differences at baseline between the 3 groups
PRIMARY OUTCOME The primary outcome measurements, √
that is, NRS scors, were decreased by an average of 2.03, 1.44, and 0.61 points in NMES, TENS, and the control groups after 20 sessions. All differences were statistically significant among the 3 groups SECONDARY OUTCOME During the current study, all groups √ displayed significant improvements in the mean shoulder AROM/PROM, FMA, BI, and SSQOLS scores at each assessment posttreatment. The treatment groups, including NMES and TENS, experienced significantly reduced NRS scores at 2 weeks, which were even further reduced at 4 weeks and maintained at 8 weeks compared to baseline. A gradual reduction could also be seen in the control group throughout the entire phase, with a significant difference at 4 and 8 weeks but not at 2 weeks. Similarly, the differences in the improvements of mean shoulder AROM/PROM, FMA, BI, and SSQOLS were statistically significant as compared to the baseline levels within each group