Cefuroxime inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs) this in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Indication Treatment of infections caused by susceptible organisms eg lower resp tract infections, UTI, skin and soft tissue infection, septicemia, meningitis, gonorrhea, bone and joint
Cefuroxime inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs) this in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Indication Treatment of infections caused by susceptible organisms eg lower resp tract infections, UTI, skin and soft tissue infection, septicemia, meningitis, gonorrhea, bone and joint
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online from Scribd
Cefuroxime inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs) this in turn inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls, thus inhibiting cell wall biosynthesis. Indication Treatment of infections caused by susceptible organisms eg lower resp tract infections, UTI, skin and soft tissue infection, septicemia, meningitis, gonorrhea, bone and joint
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online from Scribd
College of Nursing and International health Studies Fort Bonifacio, Taguig City
Name of Drug Mechanism of Indication Contraindication Adverse Effect Nursing
action Responsibility Generic Name Inhibits bacterial Treatment of Hypersensitivity Skin rash, drug Avoid prolonged Cefuroxime cell wall synthesis infections caused to cephalosporin fever, anaphylaxis, use. by binding to one by susceptible GI disturbance, or more of the organisms eg lower decreased penicillin-binding resp tract hemoglobin conc & Monitor function if Brand Name proteins (PBPs) infections, UTI, eosinophilia. with renal which in turn skin & soft tissue Axurocef impairment inhibits the final infection, transpeptidation septicemia, Transient pain at step of meningitis, the site of injection peptidoglycan gonorrhea, bone & Pregnancy & Classification synthesis in joint infections. lactation Anti-Infectives bacterial cell walls, thus inhibiting cell wall biosynthesis. Bacteria eventually lyse due to ongoing activity of cell wall autolytic enzymes.