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THYROID ANATOMY CHARACTERISTICS HISTOLOGY MANAGEMENT REMARKS


DYSFUNCTION
Diffuse non-toxic TSH Suppression Time limit: 3-6 months
Surgery (if compressive)
RAI
Diffuse toxic Hyperthyroidism treatment
Toxic Adenoma (Hot nodule) RAI
Anti-thyroid
PTCA Slow growth Psammoma bodies Surgery (Total thyroidectomy) Well-differentiated cancers
Excellent prognosis Orphan annie RAI (remnant) take up RAI
<45 – until stage II only TSH Suppression (0.1-0.4)
FTCA Poorer prognosis Hurthle cell Thyroglobulin monitoring
MTCA Familial forms (MEN, FMTCA) Surgery RAI not effective
ATCA Most aggressive
Elderly
6 months to live
Lymphoma Diffuse large cell RAI Highly sensitive to RAI
Multinodular non-toxic Prone to hemorrhage Conservative
RAI
Surgery (if compressive)
Multinodular toxic RAI Anti-thyroid medications will
Surgery (definitive) increase its size

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