1. The document discusses different types of thyroid dysfunctions and cancers including their characteristics, histology, management, and remarks.
2. Types discussed include diffuse non-toxic and toxic dysfunctions, toxic adenomas, papillary, follicular, medullary, anaplastic thyroid cancers and multinodular non-toxic and toxic conditions.
3. Management approaches mentioned are RAI therapy, anti-thyroid medications, surgery, TSH suppression, and thyroglobulin monitoring.
1. The document discusses different types of thyroid dysfunctions and cancers including their characteristics, histology, management, and remarks.
2. Types discussed include diffuse non-toxic and toxic dysfunctions, toxic adenomas, papillary, follicular, medullary, anaplastic thyroid cancers and multinodular non-toxic and toxic conditions.
3. Management approaches mentioned are RAI therapy, anti-thyroid medications, surgery, TSH suppression, and thyroglobulin monitoring.
1. The document discusses different types of thyroid dysfunctions and cancers including their characteristics, histology, management, and remarks.
2. Types discussed include diffuse non-toxic and toxic dysfunctions, toxic adenomas, papillary, follicular, medullary, anaplastic thyroid cancers and multinodular non-toxic and toxic conditions.
3. Management approaches mentioned are RAI therapy, anti-thyroid medications, surgery, TSH suppression, and thyroglobulin monitoring.
DYSFUNCTION Diffuse non-toxic TSH Suppression Time limit: 3-6 months Surgery (if compressive) RAI Diffuse toxic Hyperthyroidism treatment Toxic Adenoma (Hot nodule) RAI Anti-thyroid PTCA Slow growth Psammoma bodies Surgery (Total thyroidectomy) Well-differentiated cancers Excellent prognosis Orphan annie RAI (remnant) take up RAI <45 – until stage II only TSH Suppression (0.1-0.4) FTCA Poorer prognosis Hurthle cell Thyroglobulin monitoring MTCA Familial forms (MEN, FMTCA) Surgery RAI not effective ATCA Most aggressive Elderly 6 months to live Lymphoma Diffuse large cell RAI Highly sensitive to RAI Multinodular non-toxic Prone to hemorrhage Conservative RAI Surgery (if compressive) Multinodular toxic RAI Anti-thyroid medications will Surgery (definitive) increase its size