Professional Documents
Culture Documents
MODULE 1A
PRETEST Instruction: Please choose the letter which represents the best answer:
Reaction:
(Article Review)
With the advancement of Science and Technology, the human life is nothing but in
the pace of advancing in every aspect of Science. As we are in the 21 st century, we are greeted
with numerous discoveries, including one that brings hope for the future. In an article I have
read entitled, “ Genetic Modification of Pre-Implantation Embryos: Toward Adequate Human
Research Policies”, It has cited some key advantages on improving the overall welfare of the
human life. With the hope of eradicating genetic abnormalities, In-vitro fertilization of embryo
promises to bring a successful implantation to the bearing mother, lessening the possible
development of abnormalities on the child even before birth. With this advancement, we are
creating a better world, a better life, and a better chance of living without any irregularities for
them. While the current research efforts to modify human genes incorporate somatic cell gene
transfer intervention, somatic cells (nonreproductive) cells are being modified without sufficient
evidence of safety and efficacy, that is by attempting to successfully deliver decent functioning
of genes to children and adults. Somatic Cell Intervention has a lower chance of producing a
positive outcome since modification of genes are post-natal. Unlike the PMG, its efforts to alter
the genes of in-vitro is less likely to fail since genetic alterations at this stage produces positive
desired functional effect and compliance are high.
BENEFITS
Successful germ line interventions could enable a direct subject’s descendants to avoid
genetic disease, to avoid being a carrier of genetic disease, or to benefit from mental
and physical enhancements (Walters and Palmer 1997).
The approach could enable someone with 2 copies of the gene for Huntington’s Disease
to have a biological child unaffected by the disease. It also could allow parents to
“enhance” their children by promoting resistance to HIV infection or cancer
(Capecci 2000)
DANGER
If a germ line genetic modification had adverse effects, the burdens could fall not only on
direct subjects but on their descendants as well.
Health and Welfare if later-born children would be a major ethical and policy concern.
The current oversight system would be ill prepared to respond because of the gaps in
the current federal policies protecting human subjects, PGM studies might not receive
adequate scientific and ethical scrutiny
Whether genetic modifications in embryos were safe and effective for clinical use,
regular deficiencies and to create an opportunity to remedy the problems before PGM
studies are undertaken.
Although numerous studies have been conducted since 1990, the approach has fallen
short of earlier expectations. To date, no somatic cell intervention has produced
sufficient evidence of safety and efficacy to gain approval for clinical use (FDA 2000).
Scenario: Mrs. Cruz, a 19-year old, came to the health center for prenatal checkup. She is on
her second month of pregnancy and with complaints of frequent vomiting and dizziness.
Although she does not smoke but their clients in the videoke bar does. She also drinks
occasionally when offered by clients. She would not have seek prenatal check-up if not for her
problems. Upon assessment, her BP was 90/60mmHg, RR- 110 bpm and PR 98bpm.
6) Encourage
patient to
sleep at
least 8 hrs.
a day.
Rationale:
Sleeping helps
to reduce stress
and improves
health
circulation.
7) Reinforce
the
importance
of adhering
to
treatment
regimen
and keeping
follow up
appointmen
ts.
Rationale: To
reduce the risk
of pregnancy
complications.
8) Instruct in
and
encourage
9) Provide
comfort
measures.
Learning Skills
A bit
confused
Perfect!
Can’t understand
1. I CAN IDENTIFY the
periods when the
developing body
systems of the fetus
are most susceptible to
genetic disorders.
2. I CAN COMPARE
different theories of
procreation.
3. I CAN CONSTRUCT
appropriate nursing
diagnosis and nursing
measures to prevent
4. I CAN RECOGNIZE
environmental hazards
that may predispose
genetic abnormalities
POST TEST: Please choose the letter which represents the best answer
4.) Teratogens may greatly cause abnormalities to the growing fetus during this stage
a. First trimester c. Third trimester
b. Second trimester d. All the time
c.
5.) The most common genetic abnormality that may occur during pregnancy is
a. Down syndrome c. Trisomy 18
b. Twins d. None of them