PEPITO, RICA ALYSSA M.

UNIVERSITY OF CEBU SCHOOL OF MEDICINE Source: Harrison’s Principles of Internal Medicine 20 th Edition

Prevention and Early Detection of Cancers (Ch. 66)

PRIMARY PREVENTION SECONDARY PREVENTION

BREAST CERVICAL COLON LUNG OVARIAN PROSTATE

EDUCATION & HEALTHFUL HABITS CHEMOPREVENTION
CANCER CANCER CANCER CANCER CANCER CANCER

Increased Upper Papinicolaou Prostate

Smoking Dietary Energy Aerodigestive Prostate SURGICAL Breast self Fecal occult Low-dose CT
Physical Sun Avoidance Colon Cancer Breast Cancer VACCINATION (pap) smear CA-125 Specific
Cessation Modification Balance cancer PREVENTION examination blood testing Scan
Activity Tract Cancers and cytology Antigen

Nonavalent
decreased risk each 5 kg/m2 Adenoma SERMs Colonoscopy
SCC – smoking Hepatitis B HPV vaccine - Cervical (+) BRCA 1 & 2 Clinical breast Transvaginal Digital Rectal
Tobacco- of colon and increase in regression – (Tamoxifen, HPV Testing &
high fat diet - cessation vaccine cervical and Dysplasia mutations examination ultrasound Examination
related breast cancer BMI – prevents NSAIDs like Raloxifene) Sigmoidoscopy
increased risk 5-α-reductase anal cancers
cancers: Lung, increased risk melanoma and piroxicam,
for breast, inhibitors
larynx, for cancers of non- sulindac,
colon, (Finasteride,
oropharynx, uterus, melanoma aspirin
prostate, and dutasteride)
esophagus, gallbladder, skin cancers Oral 2-dose Prophylactic Fecal DNA &
endometrium Aromatase Electrosurgical Mammograph
kidney, kidney, cervix, leukoplakia - schedule for 9- bilateral Immunochemi
bladder, colon, Inhibitors excision y
thyroid, and toxic doses of 14 yo mastectomy cal testing
pancreas, and leukemia isotretinoin
stomach (13-cis-retinoic diets high in
acid calcium
3-dose Prophylactic Magnetic
CT
high BMI – Sunscreens - schedule for Conization salpingo- Resonance
colonography
dietary fiber - reduced risk decrease the 15-26 yo oophorectomy Imaging
reduced risk of for prostate risk of actinic
colonic polyps and keratoses Cancer of the estrogen +
lowers 10-year and invasive premenopaus (precursor to oropharynx – progestin
lung cancer cancer of the al breast SCC) HPV vaccine
mortality rate colon cancer (particularly Hysterectomy Tomosynthesis
by 30–50% including HPV-
16)

Genetic
screening for
BRCA 1 & 2