PRECIPITATING FACTORS PRE DISPOSING FACTOR

 Immunization: No vitamin K and other vaccines Age: 1-month old

 Diet: Exclusively breastfed
 Religion: Does not consume enough meaty products

Uses herbal medicine as medicinal regimen

Not yet fully developed organs

Little amount of vitamin K

stored in the body Liver does
Lack of vitamin K source
not use
vitamin K
efficiently
Vitamin K Deficiency

Low production of coagulation factor II

No converted thrombin

Acquired Prothrombin Complex

Deficiency

Prolonged PT and PTT

(PT – 14 secs | PTT – 50.2 secs)

Decreased coagulation

Bleeding

Intracranial hemorrhage Hemolysis

Degraded heme portion is

Presence of blood in lateral converted to porphyrin
ventricles
Protoporphyrin breaks down
into indirect bilirubin
Increased intracranial
pressure
Cannot convert indirect
bilirubin to direct bilirubin
 Increased unconjugated bilirubin
6th cranial nerve Weakness Vomiting (12mg/dL)
is affected

Enterophatic circulation
Crossed eyes
Downward gaze
Jaundice
Periventricular edema /
swelling

Effective (+) yellowish skin

Phototherapy breastfeeding (+) yellow stool
Fever Hard, bulging
(37.9 ˚C) fontanelles
Delay passage of
Photo - oxidation
meconium
VP Shunting
Heart rate Increased head
(167 ˚C) circumference Oxygen to the Absorption of
Incision behind ear, small
(48cm) bilirubin bilirubin
hole through the skull

A catheter is inserted into Dissolves bilirubin

the brain to the abdomen Normal color of
stool
Excess fluid was drained Unconjugated
through the abdominal bilirubin in the blood
cavity

Fluid Normal color of

skin

LEGEND:

Disease Process

Manifestation

Medical Management