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allergen: leukotrienes: antigens), binding to tissue or serum proteins to

substance that causes manifestations of allergy a group of chemical mediators that initiate the inflammatory produce a carrier complex that initiates an
allergy: response antibody response.
inappropriate and often harmful immune system response to mast cells:
substances that are normally harmless connective tissue cells that contain heparin and histamine in their
anaphylaxis: granules
rapid clinical response to an immediate immunologic reaction prostaglandins:
between a specific antigen and antibody unsaturated fatty acids that have a wide assortment of biologic
angioneurotic edema: activity
condition characterized by urticaria and diffuse swelling of the serotonin:
deeper layers of the skin (i.e., angioedema) chemical mediator that acts as a potent vasoconstrictor and
antibody: bronchoconstrictor
protein substance developed by the body in response to and T cells:
interacting with a specific antigen lymphocyte cells that can cause graft rejection, kill foreign cells, or
antigen: suppress production of antibodies
substance that induces the production of antibodies urticaria: hives
antihistamine:
medication that opposes the action of histamine IgG, IgA, IgM, IgD, IgE
atopic dermatitis:
type I hypersensitivity involving inflammation of the skin B-cell
evidenced by itching, redness, and a variety of skin lesions -b lymphocytes
atopy: -programmed to produce one specifici antibody
term often used to describe immunoglobulin E–mediated -On encountering a specific antigen, B cells stimulate
diseases (i.e., atopic dermatitis, asthma, and allergic rhinitis) with production of plasma cells, the site of antibody
a genetic component production.
B cells:
lymphocyte cells that are important in producing circulating T Cell
antibodies -assist the bcells
bradykinin: -secrete substances that direct the flow of cell activity,
a substance that stimulates nerve fibers and causes pain destroy target cells, and stimulate the macrophages
eosinophil: granular leukocyte -T cell does not bind free antigens.
erythema: diffuse redness of the skin
hapten: incomplete antigen
Function of Antigens
histamine:
-Antigens are divided into two groups:
substance in the body that causes increased gastric secretion,
dilation of capillaries, and constriction of the bronchial smooth complete protein antigens and low– molecular-
muscle weight substances
hypersensitivity: -Complete protein antigens, such as animal
abnormal heightened reaction to a stimulus of any kind dander, pollen, and horse serum, stimulate a
immunoglobulins: complete humoral response
a family of closely related proteins capable of acting as antibodies -Low–molecularweight substances, such as
medications, function as haptens (incomplete

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