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Diagnostics In The Palm Of Your Hand
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Electrochemiluminescence: A camera phone quantitatively captures signals Cloud
Rajendrani Mukhopadhyay

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A sheet of paper and a mobile phone
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together could create a cheap, portable
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alternative to typical laboratory-based
and expensive diagnostic techniques.
Researchers in Australia have created a Related Stories
simple medical device that generates
SERS On The Cheap
signals based on
electrochemiluminescence (ECL) that Related ACS Journals
camera phones can capture (Anal. Electrogenerated
Chem., DOI: 10.1021/ac102392t). Chemiluminescence Detection in
Paper-Based Microfluidic Sensors
Colorimetry and electrochemistry are Anal. Chem., DOI: 10.1021/ac102392t
already standard ways to detect Advertise Here
Anal. Chem. molecules in paper devices. But Topics Covered
MOBILE DIAGNOSTICS A analytical chemist Conor Hogan and Paper, diagnostic, camera phone,
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smartphone captures an colleagues at Australia's LaTrobe and electrochemiluminescence,
electrochemiluminescent signal from Monash Universities picked ECL, in NADH
a paper device. which an electrochemical potential
controls a light-producing chemical Latest News
reaction. ECL provides the benefit over electrochemistry of high detection
January 31, 2011
sensitivity. Unlike with colorimetry, luminescence detection doesn't depend
Gabor Somorjai Lauded For
on the availability of daylight or artificial lighting.
Research Accomplishments
The investigators fabricated the devices by inkjet printing channels onto filter Awards: Lucrative prize from Spanish
paper and embedding into one end of a channel tris(2,20- banking group recognizes chemist's
bipyridyl)ruthenium(II) (Ru(bpy) 3 2+ ), which gives off light when it reacts contributions to surface science and
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with an oxidant. Hogan and colleagues then laminated the paper to attach it
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Hogan and colleagues detected NADH at just 72 μM, a lower concentration has mixed activity that was exclusive to pharmaceutical ingredient
than achievable by paper colorimetry. They also showed that a Samsung nature. synthesis needs
smartphone quantitatively captured signals from a different analyte. Parallel Printing At The Nanoscale
Schrodinger : Download this
Lithography: Simplified patterning
Chemical engineer Robert Pelton at McMaster University, in Ontario, software to perform rapid pKa
method reproducibly yields thousands of
says, "This work is a nice example of how you can integrate" ECL and camera predictions accurately and easily
copies.
phones to photograph and email data from paper devices.
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http://pubs.acs.org/isubscribe/journals/cen/89/i05/html/8905scene1.html[1/02/2011 9:31:47 PM]


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ISSN 0009-2347
Copyright © 2011 American Chemical Society

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