Important MCQs

first block 2018

Important MCQs 2018

Protein
1- Regarding amino acids that share in protein structure
a) All have L- configuration.
b) All have D- configuration.
c) Have D or L
d) None of the above.
2- Regarding the solubility of amino acids
a) All are soluble
b) Only amino acids with charged groups are soluble.
c) Only with charged or polar groups are soluble.
d) Amino acids with non polar groups need carrier.
3- Proteins absorb lights at wave length 280nm , due to presence of which amino acid
a) Lysine
b) Tryptophan
c) Glycine
d) Basic amino acids.
4- An amino acid which does not have a specific transfer RNA is
a) Leucine
b) Hydroxyproline
c) Hydroxyl phenyl alanine
d) Proline
5- Diet proteins are important as they are the main source for
a) Carbons
b) Carbons & Hydrogen.
c) Carbons & Oxygen.
d) Nitrogen & sulfur.
6- Denaturation of protein occur with all of the following except :-
a) Temperature
b) Acids
c) Alkali.
d) Biological agents.
e) solvents
7- Proteins act as a blood buffer mains due to the residue of which amino acid:-
a) Glutamine
b) Histidine
c) Valine
d) Tryptophan.
8- Which of the followings amino acids fit in any turn of proteins?
a) Glycine
b) Proline
c) Isoleucine
d) Tyrosine
e) Any amino acids with hydrophobic chains

1
Important MCQs 2018

9- What bonds keep the amino acids together in denaturated protein

a) Non- covalent
b) Hydrogen bonds
c) Ionic bond
d) Hydrophobic interaction
e) Peptide bonds.
10- Creatine kinase enzyme is described as beings formed of two subunits, this called
a) Sequencings
b) Motifs
c) Domians
d) Superfoldings
e) Quaternary structure.
11- Which of the following is the largest molecule?
a) Glycine
b) Glutamic acid
c) Glutathione
d) Glucose
e) Glycogen.
12- Serine is important in the structure of some proteins as it provide which of the following
groups?
a) Amino
b) Sulfhydryl
c) Carboxyl
d) Guanido
e) Hydroxyl.
13- Which of the following is a Nitrogen containing compounds
a) Alanine
b) Glucose
c) Glycerol
d) Palmitate
e) Phosphatidic acid.
14- Intra-chain hydrogen bonds may not stabilize which of the followings :-
a) Alpha helix
b) Beta pleated sheet
c) Tertiary structure
d) Quaternary structure.
15- The back bone of polypeptide chain is formed of
a) N-C-C-N-C
b) C-N-C-N
c) N-C-N-C
d) C-N-N-C

Answers of proteins

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
d a b b d d b a e e e e a d a
2
Important MCQs 2018

Enzymes
1- A Coenzymes :-
a) Heat stable organic compounds.
b) Called prosthetic groups when tightly bounded to enzyme
c) Usually synthesized from vitamin B complex.
d) May be loosely attached to enzyme as NAD.
e) All of the above.
2- An apoenzymes :-
a) Is the protein part of holoenzyme
b) The non-protein part of holoenzyme
c) Is the coenzyme
d) Protein part plus prosthetic part.
3- The first digit of the four-digit classification number is :-
a) 0-4
b) 1-4
c) 0-6
d) 1-6
4- Angiotensin converting enzyme convert the decapeptide angiotensin I to octapeptide
angiotensin II , this enzyme is considered
a) Peptidease
b) Dehydrogenase
c) Ligase
d) Aminotransferase
e) Isomerase.
5- An Holoenzyme mean :-
a) The protein part of the enzyme
b) The in active enzyme
c) The prosthetic group
d) The protein part + coenzyme.
6- The name of pepsin enzyme with digit number is 3.5.7.1 that is means it is from which
class
a) Oxidoreductase
b) Transferase
c) Lyase
d) Hydrolase.
7- Biotin coenzyme work in
a) Decarboxylation reactions
b) Dehydrogenation
c) Carboxylation
d) Amino acid catabolism
8- Glucokinase is
a) Relative specificity
b) Group specificity
c) Sterospecificity
d) Absolute specificity.

3
Important MCQs 2018

9- Chymotrypsin
a) Can degrade all peptide bonds
b) Specific for hemoglobin only
c) It degrades peptide bond attached to specific type of amino acids
d) Can cleave all covalent bonds.
10- Pyridoxal phosphate :-
a) Is a coenzyme for amino acid catabolism
b) Is essential for oxidative decarboxylation reaction
c) Is a carrier of one carbon units
d) Essential for carboxylation reaction.
11- An enzymes whose concentration is fixed may be called
a) An inducible enzymes
b) A constitutive enzyme
c) A key enzymes
d) Any of the above.
12- Methorexate act as Anticancer agent as it can inhibit :-
a) Thymidylate synthase
b) PRPP synthase
c) Dihydrofolate reductase
d) Folic acid synthesis
e) Uridinie synthase
13- Initial velocity of the enzyme catalyze reaction in which of the followings :-
a) Velocity before adding the enzyme
b) The lowest velocity
c) Velocity before accumulation of products
d) Velocity at zero substrate concentration
e) Velocity at substrate concentration equal to Km.
14- A Pro-enzyme is which of the followings :-
a) An inorganic cofactor
b) A substrate need for enzyme action
c) The protein part of the enzyme
d) Enzyme with different electrophoretic pattern
e) An inactive enzyme.
15- Allopurinol inhibit conversion of
a) Hypoxanthine to IMP
b) Uric acid to Xanthine
c) Adenine to Hypoxanthine
d) Hypoxanthine to Xanthine
e) Adenine to guanine.
16- What is mean of enzyme activity
a) The conversion of proenzyme to corresponding enzyme
b) The activation energy of the enzyme catalyze the reaction
c) The concentration of the enzyme relative to substrate.
d) The amount of substrate converted to products in defined time.
e) The ability of the enzyme to bind to substrate irreversibly.
4
Important MCQs 2018
17- Which line represents the non-competitive inhibitors?
a) A
b) B
c) C
d) D
e) E
18- Michaeils constant is usually expressed in unit of ?
a) Substrate concentration
b) Reaction velocity
c) Enzyme activity
d) Reaction time
e) Ration of maximal velocity.
19- Isoenzymes are characterized by :
a) They are proteins having quaternary srtucture.
b) They have the same Km for the substrate.
c) They have different substrates.
d) They have the same electrophoretic mobility.
20- The type of LDH that increases in myocardial infarction :
a) LDH3.
b) LDH5.
c) LDH1.
d) LDH4.
e) LDH2.

Answers of enzymes
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
e a d a d d c d c a b c c e d d b a a c

Thiamine Thiamine pyrophosphate Oxidative decarboxylation

Lipoic acid Lipoic acid Oxidative decarboxylation
Niacin NAD+ & NADP+ dehydrogenation
Riboflavin FMN & FAD dehydrogenation
Pantothenic CHO-FAT- PROTEIN
CoASH
acid metabolism
Biotin Biotin Carboxylation
Folic acid Tetrahydrofolate(FH4) Carrier of one carbon unit
pyridoxine Pyridoxal phosphate Amino acids metabolism

5
Important MCQs 2018

Carbohydrates
1- Sucrose :-
a) is a non-reducing sugar.
b) Has a free anomeric carbon.
c) Result from partial hydrolysis of carbohydrates.
d) Non of the above.
2- Lactose :-
a) Disaccharide synthesized by sweet plant roots.
b) Is a galactoside
c) Is fermented by yeast enzymes
d) Is present in only alpha not beta.
3- A glycoside is formed by attaching the sugar to another molecule at a
a) Nitrogen atom (N-glycosidic bonds).
b) Oxygen (O-glycosidic bonds)
c) Both a & b
d) Neither a nor b.
4- Isomers shown by monosaccharides includes
a) Aldose-ketose isomers
b) Anomeric & epimerism
c) D-L isomers
d) All of the above.
5- A compound with no asymmetric carbon is
a) Galactose
b) Glyceraldehyde
c) Dihydroxyacetone
d) None of the above.
6- Which of the following is true :-
a) Galactose and glucose are epimers as they differ in OH of C2.
b) Fructose and glucose are epimers as they differ in OH of C2.
c) Mannose and glucose are epimers as they differ in OH of C4.
d) Mannose & Galactose are not epimers.
7- Reference sugar is :-
a) Glucose
b) Fructose
c) Glyceraldehyde
d) Dihydroxyacetone
e) Galactose.
8- All the following convert have reducing agent “cupric to cuprous” except :-
a) Glucose
b) Galactose
c) Lactose
d) Sucrose
e) Maltose.

Answers of Carbohydrates
1 2 3 4 5 6 7 8
a b c d c d c d

6
Important MCQs 2018

Lipids
1- Hexanoic acid is a fatty acid which contains
a) Six carbons atoms
b) One methyl group , one carboxyl group & four methylene groups
c) Both a & B
d) Nether a nor b
2- Lysolecithin
a) an example of lysophospholipids
b) Contain only one fatty acids
c) Result from the action of phospholipase A2
d) All of the above.
3- Phospholipase A2 from snake venom converts phosphatidyl choline to
a) Sphingomyelin
b) Phsphatidic acids
c) Lysolecithin
d) Diacylglycerol
e) Phophatidyl ethanolamine
4- What is meant by omega-3 fatty acid
a) Fatty acids with 3 double bonds
b) Three fatty acids attached to glycerol
c) There is a double bonds between carbon 3 & 4
d) A double bonds is at third carbon from the methyl end of fatty acid.
e) Fatty acid attached to carbon 3 of glycerol.
5- Phospholipids suit the membrane structure because
a) The contain phosphorus
b) Contain –ve & +ve chare
c) Contain fatty acids
d) High molecular weight
e) Are amphipathic.
6- Ceramide is essential component of all the following except
a) Sufatide
b) Sphingomyelin
c) Glucocerebroside
d) cardiolipin
7- glycerophopholipids include all of the following except :
a) cephalin
b) lecithin
c) plasmalogen
d) sphingomyelin
8- sulfatides :-
a) are present in high amounts in myelin
b) are sulfated glucocerebrosides.
c) Have asulfate attached to sphingosine
d) Is galactocerebroside sulfated at carbon 3 of galactose.