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  • Ulcer Pathophysiology

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    joyrena ochondra
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    This document discusses peptic ulcers. It lists non-modifiable factors that can cause peptic ulcers such as age, stomach cancer, and NSAIDs. It also discusses modifiable factors like diet and lifestyle. It describes the topical and systemic effects of hydrochloric acid and increased pepsin secretion on the stomach lining and how this can cause an inflammatory cascade and mucosal damage leading to ulcer formation. It lists common signs and symptoms of peptic ulcers and notes treatment depends on the underlying cause but often involves antibiotics and proton pump inhibitors if H. pylori infection is present.

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    ULCER-PATHOPHYSIOLOGY (1)

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    This document discusses peptic ulcers. It lists non-modifiable factors that can cause peptic ulcers such as age, stomach cancer, and NSAIDs. It also discusses modifiable factors like diet and lifestyle. It describes the topical and systemic effects of hydrochloric acid and increased pepsin secretion on the stomach lining and how this can cause an inflammatory cascade and mucosal damage leading to ulcer formation. It lists common signs and symptoms of peptic ulcers and notes treatment depends on the underlying cause but often involves antibiotics and proton pump inhibitors if H. pylori infection is present.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    10 views1 page

    Ulcer Pathophysiology

    Uploaded by

    joyrena ochondra
    This document discusses peptic ulcers. It lists non-modifiable factors that can cause peptic ulcers such as age, stomach cancer, and NSAIDs. It also discusses modifiable factors like diet and lifestyle. It describes the topical and systemic effects of hydrochloric acid and increased pepsin secretion on the stomach lining and how this can cause an inflammatory cascade and mucosal damage leading to ulcer formation. It lists common signs and symptoms of peptic ulcers and notes treatment depends on the underlying cause but often involves antibiotics and proton pump inhibitors if H. pylori infection is present.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    Non Modifiable Factors

    PEPTIC ULCER Modifiable Factors

     Age  Diet and Lifestyle


     Stomach Cancer
     NSAIDS-
    Nonsteroidal anti-
    inflammatory
    drugs

    Topical and systemic Hydrogen ions and Release of cytokines,


    effects incrasr pepsin lipopolysaccharide, heat-
    secretion shock protein enzymes
    etc.

    Decreased mucus
    production, decreased
    blood flow, increased Inflammatory cascade
    neutrophils, decreased initiated (cytokines,
    bicarbonate, decreased neutrophils,
    cell restitution. lymphocytes,etc)

    Signs and Symptoms Mucosal damage


    • changes in appetite and ulceration Treatment will depend on the
    underlying cause of your ulcer. If tests
    • nausea show that you have an H.
    • bloody or dark stools pylori  infection, your doctor will
    prescribe a combination of medication.
    • unexplained weight You’ll have to take the medications for
    loss
    up to two weeks. The medications
    • indigestion include antibiotics to help kill infections
    and proton pump inhibitors (PPIs) to
    • vomiting
    help reduce stomach acid.
    • chest pain

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