DRUG STUDY

NAME____________________________________________________________ AGE____________
DIAGNOSIS_________________________________________________

DRUGS ACTION INDICATION CONTRAINDICATION ADVERSE EFFECT NURSING CONSIDERATION

Generic Name:  Analgesic and  Mild to moderate
Aspirin antirheumatic effects
are attributable to  Fever
Brand name: aspirin’s ability to
Aspergum inhibit the synthesis of
prostaglandins,
Classification: important mediators
 Analgesic of inflammation.
 Anti-  Antipyretic effects are
inflammatory not fully understood,
 Antiplatelet but aspirin probably
 Antipyretic acts in the
 Reduction of risk
 Antirheumatic thermoregulatory
 NSAID center of the
 Salicylate hypothalamus to block
effects of endogenous
pyrogen by inhibiting
Dosage:
synthesis of the
51-325mg/day
prostaglandin
intermediary.
 People with allergy to
pain salicylates or NSAIDs. This is
more common to people with
Inflammatory nasal polyps, asthma, and
conditions chronic urticaria.
such as  People with haemophilia,
rheumatic allergy to tartrazine (cross-
fever, sensitivity is common),
arthritis, and bleeding ulcers, blood
coagulation defects, and with
spondyloarthr
Vitamin K deficiency
opaties
(increased risk of bleeding)

Caution with people who have
of recurrent
impaired renal function,
transient ischemic
children and teenagers (risk
attack (precursor for developing Reye’s
to stroke) or Syndrom), patients who will
cardiovascular have surgery within 1 week,
accident (stroke) in and pregnant women (it
patients with readily crosses placenta and is
history of TIA due a possible teratogen) as well
to fibrin platelet as lactating mothers.
emboli or ischemic
stroke
 Acute aspirin toxicity:
respiratory alkalosis,
hemorrhage, tachypnea,
confusion, asterixis, pulmonary
edema, seizures, tetany,
metabolic acidosis, renal and
respiratory failure
 Aspirin intolerance:
exacerbation of bronchospasm,
rhinitis
 Gastrointestinal: nausea,
dyspepsia, heartburn, epigastric
discomfort, anorexia,
hepatotoxicity
 
Hematologic: occult blood loss,
hemostatic defects
 Hypersensitivity: anaphylactoid
reactions to anaphylactic shock
 Salicylism: dizziness, tinnitus,
difficulty hearing, nausea,
vomiting, diarrhea, mental
confusion
 Assess skin color and presence of lesions as this
may indicate hepatotoxicity, allergy, bleeding,
and other complications.
 Give drug with food or after meal if GI upset
occurs.
 To reduce the risk of the tablet lodging in the
esophagus, give drug with full glass of water.
 Ensure that patient does not crush and chew
tablets as well as sustained release preparations
to prevent losing drug’s effectivity.
 In case of overdose, institute emergency
procedures and prepare equipments for gastric
lavage, induction of emesis, and activated
charcoal.
•Observe patient for signs and symptoms of
bleeding such as easy bruising, bleeding in the
gums, and nosebleeds.
 Monitor vital signs.
 Raise side rails up to ensure patient’s safety.
 Monitor for signs and symptoms of drug allergy
such as difficulty of breathing, pruritus, and
rashes.

Prepared by:

March 2, 2019 Prof. Marcial Mesias De V MAN

Steven Matthew L. Dasig
Student Nurse and Signature DATE Clinical Instructor