DRUG STUDY FORMAT

Name of Patient : _Mrs. P_ Patient's Health Profile: _patient appears mildly anxious,
Age : _77 yrs. old_ Sex:_F_ _non-dyspneic_
Occupation : _N/A_
Date of Admission :_N/A_
Status : _Married_ Religion : _N/A_ Initial Compliant : _currently experiencing mild confusion, fatigue,
_abdominal pain, and weakness.
Diagnosis : _N/A_

Name of Classification Mechanism of ContraIndicatio Indication Side Effects Nursing

Drug: Action n Route and Dosage Responsibilities
Generic
Name:
Brand
name:
1. Generic Loop diuretic, Furosemide Indication:  peeing more than  Assess for the
name: antihypertensiv inhibits Furosemide is  Hypertension normal mentioned
Furosemide e primarily the contraindicated  feeling thirsty with a dry cautions and
absorption of in patients with Route: Oral mouth contraindications
Brand sodium and anuria and in Dosage: 20mg daily  headaches to prevent any
name: chloride not patients with a  feeling confused or dizzy untoward
Lasix only in the history of  muscle cramps or weak complication.
proximal and hypersensitivity muscles  Perform a
distal tubules to furosemide.  feeling or being sick thorough
but also in the  nausea or vomiting physical
loop of Henle.  fast or irregular assessment to
The high heartbeat establish
degree of baseline data
efficacy is before drug
largely due to therapy begins,
this unique site to determine
of action. The effectiveness of
action on the therapy, and to
distal tubule is evaluate for
independent of occurrence of
any inhibitory any adverse
effect on effects
carbonic associated with
anhydrase and drug therapy.
aldosterone.  Inspect skin to
determine
hydration status
and have a
baseline data for
effectiveness of
drug therapy.
 Assess
cardiopulmonary
status to
evaluate fluid
movement and
state of
hydration. It is
also to monitor
the effects on the
heart and lungs.
 Obtain an
accurate body
 weight to provide
baseline to
monitor fluid
balance.
 Monitor intake
and output and
voiding patterns
to evaluate fluid
balance and
renal function.
 Evaluate liver
status to
determine
potential
problems in drug
metabolism.
 Monitor the
results of
laboratory tests
to determine
drug’s effect.
 Monitor liver and
renal function
tests to identify
need for possible
dose adjustment
and toxic effects.

2. Generic Corticosteroids Beta-2 Indication:  Hoarseness  Assess for

name: adrenoceptor Salmeterol is  used to treat  throat irritation possible
Salmeterol stimulation COPD  headache contraindications
causes contraindicated  rapid heartbeat or cautions: any
Brand relaxation of for Route: Oral Inhalation  nervousness known allergies
name: bronchial monotherapy  cough to prevent
Serevent smooth muscle, treatment of Dosage: 2 inhalations  dry mouth/throat hypersensitivity
bronchodilation asthma. It b.i.d.  upset stomach reactions.
, and increased should not be  Perform a
airflow. used without physical
Salmeterol is an asthma examination to
hypothesized controller establish
to bind to 2 medication. baseline data for
sites on the Salmeterol assessing the
beta-2 should not be effectiveness of
adrenoceptor. used in patients the drug and the
The saligenin who have occurrence of
moiety binds to demonstrated a any adverse
the active site hypersensitivity effects
of the beta-2 reaction to associated with
adrenoceptor. salmeterol or to drug therapy.
any of the  Perform a skin
components in examination,
the commercial including color
product. and the presence
of lesions, to
provide a
baseline as a
reference for
drug
effectiveness.
 Monitor blood
 pressure, pulse,
cardiac
auscultation,
peripheral
perfusion, and
baseline
electrocardiogra
m to provide a
baseline for
effects on the
cardiovascular
system.
 Assess bowel
sounds and do a
liver evaluation
and monitor liver
and renal
function tests to
provide a
baseline for renal
and hepatic
function tests.
 Evaluate urinary
output and
prostate
palpation as
appropriate to
monitor
anticholinergic
 effects.
 Evaluate
orientation,
affect, and
reflexes to
evaluate CNS
effects.

3. Generic Anticholinergic Ipratropium is Indication:  Dizziness  Protect solution

Name: an Ipratropium  Used to treat  nausea for inhalation
Ipratropium acetylcholine bromide is air flow  stomach upset from light. Store
bromide antagonist via contraindicated blockage and  dry mouth unused vials in
blockade of to patients with prevent the  constipation foil pouch.
Brand muscarinic closed angle worsening of  Use nebulizer
name: cholinergic glaucoma, chronic mouthpiece
Atrovent receptors. blockage of the obstructive instead of face
Blocking urinary bladder, pulmonary mask to avoid
cholinergic enlarged disease (COPD). blurred vision or
receptors prostate, and aggravation of
decreases the an inability to Route: Oral narrow-angle
production of completely Inhalations glaucoma.
cyclic empty the  Can mix albuterol
guanosine bladder. Dosage: 2 inhalations in nebulizer for
monophosphat b.i.d. up to 1 hr.
e (cGMP). This  Ensure adequate
decrease in the hydration,
lung airways control
will lead to environmental
decreased temperature to
contraction of prevent
 the smooth hyperpyrexia.
muscles.  Have patient void
before taking
medication to
avoid urinary
retention.
 Teach patient
proper use of
inhaler.

4. Generic Bronchodilators Albuterol acts Indication:  nervousness or  Monitor

Name: on beta-2 Albuterol is Prevent and treat shakiness ECG, serum
Albuterol adrenergic contraindicated difficulty breathing,  headache electrolytes
(Salbutamol receptors to to patients with wheezing, shortness  throat or nasal irritation and thyroid
) relax the overactive of breath, coughing,  muscle aches function test
bronchial thyroid gland, and chest tightness  tachycardia results.
Brand smooth muscle. diabetes, caused by COPD.  palpitations  Administer
Name: It also inhibits ketoacidosis, the
Proventil, the release of excess body Route: Oral Inhalation medication
Ventolin immediate acid, low accurately
hypersensitivity amount of Dosage: 2 puffs prn. because
mediators from potassium in q.4h adverse
cells, especially the blood, high reactions
mast cells. blood pressure, and
diminished tolerance
blood flow might occur.
through  Raise side
arteries of the rails up
heart, low because
supply of
 client might
oxygen rich be restless
blood to the and drowsy
heart, because of
prolonged QT this drug.
interval on EKG,  Keep room
abnormal heart well-lit and
rhythm, see to it that
abnormal EKG client has a
with QT person with
changes from him closely
birth, and in case of
seizures. vertigo.
 Assess lung
sounds, PR
and BP
before drug
administrati
on and
during peak
of
medication.
 Assess pulse
for rhythm.
 Provide oral
care or let
patient
gurgle after
inhalation to
get rid of the
 unpleasant
aftertaste of
the
inhalation.
 Auscultate
lungs for
presence of
adventitious
breath
sounds that
may signal
pulmonary
edema,
airway
resistance or
bronchospas
m.
 Inspect
client’s nail
bed and oral
mucosa for
pallor.
  Place client
in position of
comfort to
facilitate
optimum
rest and
sleep.
5. Generic Statins Atorvastatin is Indication:  diarrhea  Obtain liver
Name: a selective, Atorvastatin is  Used to lower  Cold symptoms function test as a
Atorvastatin competitive contraindicated cholesterol. It  Joint pain baseline and
inhibitor of to patients with also prevents  Insomnia periodically
Brand HMG-CoA untreated heart disease,  UTI during therapy.
Name: reductase, the decreased level including heart  Nausea Discontinue drug
Lipitor rate- limiting of thyroid attacks.  Loss of appetite if AST or ALT
enzyme that hormones,  Indigestion symptoms levels increase to
converts 3- alcoholism, Route: Oral 3 times normal
 Increased transaminases
hydroxy-3- hemorrhage in levels.
 Muscle spasms
methylglutaryl- the brain, liver Dosage: 40mg daily  Withhold
 Musculoskeletal pain
coenzyme A to failure, liver atorvastatin in
 Muscle pain
mevalonate, a problems, any acute,
 Limb pain
precursor of decreased serious condition
 Mouth and throat pain
sterols, kidney function, that may suggest
rhabdomyolysis  Chest pain (angina)
including myopathy or
, recent  Lightheadedness and
cholesterol. serve as risk
operation, fainting
factor for
memory loss,  Shortness of breath or
development of
high blood other breathing
renal failure.
sugar, problems
 Ensure that
abnormal liver  Muscle weakness or loss
patient has tried
function tests, of muscle strength
cholesterol-
major  Anaphylaxis
lowering diet
traumatic  Stevens-Johnson
regimen for 3–6
injury, syndrome
months before
pregnancy,  Muscle inflammation
beginning
lactating therapy.
mother, muscle  Administer drug
pain or without regard to
 food, but at same
tenderness time each day.
with increase  Atorvastatin may
creatine kinase, be combined
and immune- with a bile acid–
mediated binding agent. Do
necrotizing not combine with
myopathy. other HMG-CoA
reductase
inhibitors or
fibrates.
6. Generic Anticoagulants Heparin Indication:  Bruising more easily.  Adjust dose
Name: catalyzes the Heparin is  Used to treat  Bleeding that takes according to
Heparin inactivation of contraindicated and prevent longer to stop. coagulation test
thrombin by to patients with blood clots in  Irritation, pain, redness, results
Brand ATIII by acting uncontrolled the veins, or sores at the injection performed just
Name: as a template bleeding or a arteries, or site. before injection.
Hemochron to which both severe lack of lungs.  Allergic reactions, such  Always check
Hep-Lock the enzyme platelets in the as hives, chills, and fever. compatibilities
and inhibitor blood, or have Route: Subcutaneous  Increased liver enzymes with other IV
bind to form a low platelets on liver function test solutions.
ternary caused by using Dosage: 5000 units results.  Use heparin lock
complex. heparin or b.i.d. needle to avoid
pentosan repeated
polysulfate. injections.
 Give deep
subcutaneous
injections. Do not
give heparin by
IM injection.
 Apply pressure to
all injection sites
after needle is
withdrawn.
Inspect injection
sites for signs of
hematoma. Do
not massage
injection sites.
 Mix well when
adding heparin to
IV infusion.
 Do not add
heparin to
infusion lines of
other drugs, and
do not piggyback
other drugs into
heparin line. If
this must be
done, ensure
drug
compatibility.
 Provide for safety
measures to
prevent injury
from bleeding.
 Check for signs of
bleeding;
monitor blood
 tests.
 Alert all health
care providers of
heparin use.
 Have protamine
sulfate (heparin
antidote) readily
available in case
of overdose;
each mg
neutralizes 100
units of heparin.
Give very slowly
IV over 10 min,
not to exceed 50
mg.
7. Generic Opioid Morphine has Indication:  Constipation  Instruct patient
Name: analgesics an affinity for Morphine is  Pain relief  Nausea &vomiting how and when to
Morphine delta, kappa, contraindicated ( post and peri-  Sedation ask for pain
and mu opioid to patients with operative)  Pruritus medication. Do
Brand receptors. This hypersensitivity  Respiratory depression & not stop taking
Name: drug produces to morphine, Route: IV apnea without
Avinza the majority of head injuries,  Circulatory depression & discussing with
its analgesic impaired Dosage: 1mg every 6 shock health care
effects by pulmonary mins., lockout professional. It
binding to the function, and 10mg/h may cause
mu-opioid pregnancy. withdrawal
receptor within symptoms if
the central discontinued
nervous system abruptly after
(CNS) and the prolonged use.
peripheral  Discuss safe use,
nervous system risks, and proper
(PNS). The net storage and
effect of disposal of opioid
morphine is the analgesics.
activation of  Caution patient
descending to call for
inhibitory assistance when
pathways of ambulating or
the CNS as well smoking and to
as inhibition of avoid driving or
the nociceptive other activities
afferent requiring
neurons of the alertness until
PNS, which response to
leads to an medication is
overall known.
reduction of  Advise patient
the nociceptive that morphine is
transmission. a drug with
known abuse
potential. Protect
it from theft, and
never give to
anyone other
than the
individual for
whom it was
prescribed.
 Advise patient to
change positions
slowly to
minimize
orthostatic
hypotension.
 Caution patient
to avoid
concurrent use of
alcohol or other
CNS depressants
with this
medication.
 Encourage
patients who are
immobilized or
on prolonged
bed rest to turn,
cough, and
breathe deeply
every 2 hr to
prevent
atelectasis.
 Explain to patient
how and when to
administer
morphine and
how to care for
infusion
equipment
 properly.
8. Generic Histamine-2 Famotidine is a Indication:  fatigue  Monitor for
Name: blockers competitive Famotidine is  To decrease  vomiting improvement in
Famotidine inhibitor of contraindicated the amount of  nausea GI distress.
histamine H2- in patients with acid made in  abdominal  Monitor for signs
Brand receptors. The a history of the stomach discomfort of GI bleeding.
Name: primary serious  anorexia
Pepcid clinically hypersensitivity Route: Oral  dry mouth
important reactions to  rash
pharmacologic famotidine or Dosage: 20mg b.i.d.  muscle cramps
activity is other H2
inhibition of receptor
gastric juice antagonists.
secretion.
Famotidine
reduces the
acid and pepsin
content, as well
as the volume,
of basal,
nocturnal, and
stimulated
gastric
secretion.