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Purpose and effectiveness of psychoeducation in patients with bipolar


disorder in a bipolar clinic setting

Article  in  Acta Psychiatrica Scandinavica · May 2013


DOI: 10.1111/acps.12118

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Acta Psychiatr Scand 2013: 127 (Suppl. 442): 11–18 © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd
All rights reserved ACTA PSYCHIATRICA
DOI: 10.1111/acps.12118
SCANDINAVICA

Clinical overview
Purpose and effectiveness of psychoeducation in
patients with bipolar disorder in a bipolar clinic
setting
Stafford N, Colom F. Purpose and effectiveness of psychoeducation in N. Stafford1, F. Colom2
patients with bipolar disorder in a bipolar clinic setting. 1
Leicestershire Partnership NHS Trust, Adult Mental
Health Services, Leicestershire, UK and 2Bipolar
Objective: This article reviews psychological therapies in the treatment Disorders Unit, IDIBAPS-CIBERSAM-Hospital Clinic
of bipolar disorder, in particular psychoeducation, and how the Barcelona, Barcelona, Spain
inclusion of four fundamental principles – patient/therapist
communication, flow of information, patient involvement and a
trusting relationship – can improve patient outcomes.
Method: The content of this article is based on the proceedings of a
1-day standalone symposium in November 2011 exploring how to
establish a bipolar clinic within the context of existing services in the
UK’s National Health Service.
Results: Certain psychological interventions have emerged as beneficial
add-on treatments to pharmacotherapy in bipolar disorder and are
associated with greater stabilisation of symptoms, fewer relapses and
longer time to relapse. Psychoeducation is a simple approach to support
prevention of future episodes by delivering behavioural training to
improve illness insight, early symptom identification and development Key words: psychoeducation; bipolar disorder; patient
of coping strategies. Empowering patients to actively participate in their involvement; quality of life; bipolar clinic
treatment provides independence, counteracts the current disconnect of Nick Stafford, Leicestershire Partnership NHS Trust,
therapist and patient, and increases awareness and understanding of the Cedars Centre, Cedars Avenue, Wigston, Leicestershire
challenges of living with and treating bipolar disorder. LE18 2LA, UK.
E-mail: nicholas.stafford@leicspart.nhs.uk
Conclusion: Psychoeducation enables patients to understand bipolar
disorder, get actively involved in therapy planning, and be aware of
methods for episode prevention, therefore effectively contributing to
improved treatment outcomes and patient quality of life.

Clinical recommendations
• To improve treatment, patients should have the opportunity to voice their expectations and to
participate in the decision-making process.
• Psychoeducation is a flexible intervention that is adjusted based on patient needs and recovery
progression in the long-term management of bipolar disorder.
• Bipolar clinics provide a setting that allows patients to actively contribute to their care plan.

Additional comments
• It may be difficult for patients to seek professional help during acute episodes.
• Inclusion of family and carers in psychoeducation programmes ensures regular monitoring of patient
recovery and early identification of relapse symptoms.
• Patients with marked cognitive decline may have difficulties in understanding and implementing the
goals of psychoeducation sessions.

11
Stafford and Colom

Introduction detection was associated with a significant increase


in time to first manic relapse, as well as a 30%
Psychological treatments and their effect on patients with bipolar
decrease in the number of manic episodes and
disorder
improvement in social functioning and employ-
Bipolar disorder is a chronic illness that impacts ment over 18 months (12). However, the same
on patient quality of life (QoL) and global func- approach failed to show any significant changes in
tioning. To improve care, the role of both the a larger study with a longer follow-up (13), indicat-
patient and the specialist during the treatment ing that early warning sign recognition is only a
needs to change and requires more integrative care part of the scope of topics psychoeducation needs
rather than pharmacotherapy alone. Therefore, to address (11). Not only does psychoeducation
the current therapeutic approach for bipolar help to improve adherence to lithium in patients
disorder includes the combination of psychophar- with bipolar disorder (14), adherent patients also
macological and psychological interventions (1, 2). benefit from the intervention (15). Family psycho-
Psychological interventions have emerged in education has proven to be highly efficacious in
response to studies that have shown associations preventing manic but not depressive episodes
between socio-environmental stressors and remis- (Table 1) (4).
sion–relapse cycles of bipolar disorder. Controlled
trials indicate that adjunctive family therapy (3, 4),
What is psychoeducation?
individual cognitive behavioural therapy (CBT)
(5), and interpersonal and social rhythm therapy Psychoeducation is a simple approach aimed at
(IPSRT) (6) are associated with greater stabilisa- improving the treatment outcome of patients with
tion of symptoms, improved adherence to medica- bipolar disorder and enhancing the prevention of
tion, fewer hospital admissions, lifestyle regularity, future episodes. This type of psychological therapy
habits modification and a stable social rhythm can be offered as adjunctive treatment to standard
than comparison interventions involving medica- pharmacotherapy (11) and delivers information-
tion and – sometimes – active clinical management. based behavioural training aimed at adjusting
It has to be mentioned, however, that not all patient lifestyle and strategies of coping with
psychological interventions are equally powerful in bipolar disorder, including enhancement of illness
the treatment of bipolar disorder. Several have awareness, treatment adherence, early detection of
been successful in the treatment of unipolar relapses and avoidance of potentially harmful
depression and subsequently been adapted for factors such as substance misuse and sleep depriva-
bipolar disorder, and although efficacy may be tion (16). Psychoeducation is an intervention that
displayed (5), effectiveness and long-term out- seeks to empower patients with tools that allow
comes in bipolar disorder are less convincing (7, 8). them to be more active in their therapy process.
Psychological interventions are essential during However, it does not represent a therapy option
the maintenance phase, because most cognitive that is based on patient self-help, owing to it being
and behavioural therapy targets that allow patients highly structured and requiring a directive
to achieve good social, interpersonal and occupa-
tional functioning may only be reached once
Table 1. Content of the Barcelona Bipolar Disorder Programme psychoeducational
the patient is euthymic (9, 10). In addition, the intervention for caregivers of patients with bipolar disorder
effectiveness of psychological interventions heavily
relies on content and delivery. In a simplified way, Programme sessions
these interventions can be divided into simple and Understanding the nature of the illness
complex therapies. Complex therapies tend to have Main symptoms and early identification of prodromes: manic and hypermanic
a strong theoretical background, have their own episodes
model of understanding of the disorder to be trea- Main symptoms and early identification of prodromes: depressive and mixed
episodes
ted, and require complex training and a highly Identification of triggering factors
skilled therapist, whereas simple therapies do not Treatment: mood stabilisers
require a highly developed theoretical background, Treatment: antipsychotics and antidepressants
Family and treatment: enhancing adherence
lack complexity for patient and therapist, fit easily
Planning of coping strategies
into the clinical setting and target very specific and Emergencies: suicidal thoughts, hospitalisation, pregnancy and counselling on
limited therapeutic goals (11). genetics
Among the simple therapies, psychoeducation Prevention and management of family stress: communication skills training
Prevention and management of family stress: problem-solving training
is efficacious in unipolar depression, as well as Legal and social resources
bipolar disorder. A study based on a simple inter-
vention of training patients on early warning sign Taken from Reinares et al. (4).

12
Psychoeducation in bipolar clinics

influence by a therapist. The Barcelona Bipolar November 2011 and supplemented with the rele-
Unit was the first clinic to provide structured, vant literature. The symposium was designed to
manualised and evidence-based psychoeducation give an overview of the natural history of bipolar
therapy in a set of modular sessions (Table 2), disorder, the importance of monitoring the physi-
which have been used to develop further psycho- cal health of patients on pharmacotherapy, the
education programmes adapted to satisfy the needs importance of psychoeducation as part of standard
of other bipolar clinics (17), allowing its implemen- treatment for bipolar disorder and an example of a
tation in rather diverse countries including Spain, bipolar clinic currently in operation. The objective
UK, Denmark, Norway, France, Greece, Portugal, of the workshop and the meeting was to educate
Poland, Turkey, Italy, Chile, Argentina, Mexico, UK-based healthcare professionals (HCPs) about
Columbia, Canada, Australia, China and Japan. the opportunities, challenges and expectations
Despite reports of its prophylactic efficacy, psycho- associated with setting up a bipolar clinic with the
education is not effective in treating acute episodes resources available in their own clinical practices.
and may have limitations for use in patients with a
higher number of previous manic episodes due,
probably, to neuropsychological impairment (18). Results
Furthermore, it should always be considered an
Efficacy of psychoeducation in the management of bipolar
adjunctive treatment to pharmacotherapy (19).
disorder
The efficacy of pharmacological treatment of
Aims of the study
bipolar disorder has, on occasion, led clinicians to
This article reviews psychological therapies in the forget psychological interventions as a treatment
treatment of bipolar disorder, in particular option. However, group-based psychoeducation
psychoeducation, and how the inclusion of four shows efficacy far beyond that usually seen by the
fundamental principles – patient/therapist commu- mere supportive role of the group. Psychoeduca-
nication, flow of information, patient involvement tion is effective as an add-on to maintenance
and a trusting relationship – can improve patient pharmacotherapy in the prevention of recurrences
outcomes. in bipolar disorder – in particular, episodes of
mania/hypomania, mixed episodes and depression
(17). Psychosocial interventions are by no means
Material and methods
substitutes for pharmacotherapy, but they may
The content of this article is based on the complement mood stabilisers in protecting patient
proceedings of a 1-day standalone symposium in symptom deterioration, as well as enhance adher-
ence to maintenance treatments (3, 14).
Table 2. Content of the psychoeducation programme (Barcelona Bipolar Disorders Evidence thus far has shown that psychoeduca-
Programme, The Barcelona Bipolar Clinic)
tion in combination with pharmacotherapy is
Programme sessions more effective than pharmacotherapy alone in a
number of parameters. Long-term psychoeducation
Introduction
What is bipolar illness?
(6 months) demonstrated a positive effect on
Causal and triggering factors patient adherence to lithium (14) and a significantly
Symptoms (I): mania and hypomania lower number of hospitalisation and days spent in
Symptoms (II): depression and mixed episodes hospital up to 2 years, compared with patients
Course and outcome
Treatment (I): mood stabilisers
receiving a combination of pharmacological treat-
Treatment (II): antimanic agents ment and non-structured group meetings (17).
Treatment (III): antidepressants Additionally, the number of total episodes, but also
Serum levels: lithium, carbamazepine and valproate the number of manic, depressive and mixed epi-
Pregnancy and genetic counselling
Psychopharmacology vs alternative therapies
sodes individually, was significantly lower in
Risks associated with treatment withdrawal patients receiving psychoeducation both at 2-year
Alcohol and street drugs: risks in bipolar illness (17) and 5-year (20) follow-up. A major reason why
Early detection of manic and hypomanic episodes psychoeducation appears to be so effective and
Early detection of depressive and mixed episodes
What to do when a new phase is detected? widely used in bipolar patients is that the interven-
Regularity tion reflects a medical model of the illness, thus
Stress management techniques disregarding stigmatisation and perceptional issues;
Problem-solving techniques
therefore, psychoeducation may appeal to a
Final session
wider patient population due to its straightforward
Taken from Colom et al. (17). delivery and common-sense approach (16).

13
Stafford and Colom

Psychoeducation is meaningful in settings where


Delivering psychoeducation in a bipolar clinic setting – who
a multidisciplinary team effort is available. A team
should deliver psychoeducation?
structure enhances the availability of a member in
There is an increasing need to provide educa- the patient’s team in moments of crisis and ensures
tional therapy not only on a specialist level, but that each intervention – for example, assessing the
in a primary-care setting. Bipolar clinics offer an early warning signs, changing a medical prescrip-
environment in which the patient interacts with a tion, controlling sleep habits or performing an
variety of HCPs, ranging from mental-health urgent determination of mood stabiliser serum
nurses to psychologists, psychiatrists, occupa- levels – is performed by a different specialist within
tional therapists and pharmacists. Such resources the team. By increasing patients’ ability to manage
are not available in a primary-care setting, where their disorder, the goal is to instil a proactive atti-
many patients with bipolar disorder are diag- tude into the patient and help them to develop
nosed and treated (21). Therefore, it is important awareness for when to seek help. The frequency of
that general practitioners (GPs) are aware of the patients’ appointments with their treating psychia-
impact that psychoeducation can have on the trist should follow an open-door policy, which
recovery process and the improvement in patient allows for fewer arranged appointments, but
QoL. It is not necessary for the GP to provide complete flexibility for unscheduled visits or
psychoeducation; however, they should be willing on-call availability upon suspicion of a new epi-
to recommend this type of therapy to their sode. In addition, psychoeducation should not be a
patients. static treatment, but improved upon on a regular
A major advantage of psychoeducation is its basis, and adjusted in content and application
relevance and applicability beyond the field of depending on the patient progression, all assessed
mental health, owing to its simple approach and through a regular review regimen (11).
the fact that most skills required to provide the
intervention are transferable to a myriad of other
When should a bipolar patient receive psychoeducation?
illnesses. The simplicity of psychoeducation allows
implementation without long, complex and Adequate timing and type of psychological inter-
thorough training of the therapist. Although the vention are essential for successful treatment out-
therapist needs to be a clinician (e.g. psychiatrist, come. Patient characteristics, such as current
psychologist, nurse), he/she should have specific symptom levels or an extensive past history of
clinical experience in the field of bipolar disorders, recurrent bipolar episodes, may imply that the
rather than being an expert on a certain type of patient cannot engage with therapy or learn to
psychotherapy. Due to the nature of the delivery utilise the skills being taught (9, 18). The individ-
of psychoeducation programmes – that is, a group ual’s needs dictate the type of therapy that is used,
setting – it is important for the therapist to have with patients potentially gaining more benefit from
experience in group work and have certain per- short-term targeted interventions, such as adher-
sonal characteristics including a sense of humour, ence therapy or relapse prevention training. These
flexibility and interpersonal skills (11). therapies address problems, including adapting to
bipolar disorder, adhering to medication or identi-
fying and self-managing early warning signs of
What is the proper setting?
relapse. Psychoeducation should be attempted
Although psychoeducation follows a simple rather when a patient is stable to be able to make full use
than a skilled approach, it is often not easy to of the opportunity to participate in adaptive
implement in an overworked and overwhelmed coping strategies involving their peers in a struc-
clinical setting. Psychoeducation based on a tured treatment setting (9).
diverse team of specialists (including psychiatrists,
psychologists, and nurses) is a simple approach for
both clinicians and patients, does not require a Discussion
highly developed theoretical background, and
What are the core issues to be addressed by psychoeducation?
promotes interpersonal skills. This strategy trans-
forms the traditional model of a healing profes- The intention of psychoeducation sessions is to
sional and a passive patient into one of a trusting promote changes in patient behaviours and atti-
relationship between patient and clinician, empow- tudes in the following areas: the individual’s
ering the patient to participate in the treatment awareness and understanding of bipolar disorder;
process and the clinician to have respect for the their adherence to the treatment regimen; the
patient’s decisions. stability of their social and sleep rhythms; reducing

14
Psychoeducation in bipolar clinics

any misuse of drugs and/or alcohol; and the wall between patients and professionals. Patients
individual’s ability to recognise and manage the have important insights and priorities that doctors
prodrome of bipolar relapse or the internal and and other HCPs lack (24). In a survey performed
external stressors that may increase their vulnera- by the Care Quality Commission, 8% of patients
bility to future relapse. Often-cited psychosocial felt that they had not been given enough time to
influences are stressful life events, family conflict discuss their treatment and condition, 7% did not
(including high levels of expressed emotion), trust or have confidence in their HCP and 5% felt
chronobiological instability (such as social and that their personal views were not taken into
circadian rhythm disruption) and treatment account. However, only a small percentage of
non-adherence (9). surveyed patients felt that they were not treated
Non-adherence to medication is a common with respect and dignity (2%) or were not carefully
feature among bipolar patients and is the major listened to (3%) (25).
reason for symptom recurrence. Non-adherence
may result from the patient feeling ‘under drug Information. A lack of information and communi-
control’, illness denial, or patients missing their cation can lead to ineffective treatment, leaving
manic periods. Patients with underlying personal- both the HCP and the patient frustrated. Inade-
ity disorders may not be aware of their prodromal quate follow-up of patients on a new treatment,
symptoms or have difficulties following treatment lack of information about the purpose of a new
advice; thus, a diagnosis of personality disorder medication, potential side-effects and disregard of
correlates with an increased possibility of patient opinion often leads to patients being unpre-
non-adherence (22). Therefore, it is important to pared for adverse events, potentially disruptive
educate patients about the consequences of non- dosing regimens and possible lack of treatment
adherence, the effect this has on their own QoL, as efficacy (26). These are only some of the factors
well as the effect on their family and friends. that contribute to 90% of HCPs suggesting that
Psychoeducation, more than being a technique, non-adherence is the main reason for treatment
is an attitude when treating the patient, with the failure (25), a situation that could be fundamen-
underlying aim of improving the relationship tally improved by a good patient–HCP dialogue.
between patient and therapist to a level that allows Evidence suggests that when patients are
both parties to readjust responsibilities and expertise adequately educated about their illness and sup-
in the treatment process. This intervention does ported to participate in the decision-making pro-
not cure bipolar disorder, but aids in the elimina- cess, healthcare outcomes are better, services are
tion of incomprehension and denial, alleviates used more appropriately, patient satisfaction is
stigma, deals effectively with guilt and prevents higher and there is less risk of litigation (27). This
learned helplessness (16), factors that seriously suggests a bidirectional flow of information, not
impede a patient’s physical and mental wellness. just from HCP to patient, but inadvertently from
patient to HCP. Psychoeducation programmes
have been devised (17, 28) to enable patients to
Empowering patients with bipolar disorder and improving their
gather information about various aspects of their
quality of life
disorder. However, only 50% of patients have been
Psychoeducation is based on the principle that to introduced to the concept of psychoeducation, and
improve care, the role of both the patient and the a staggering 86% failed to voice their desire to
specialist during the treatment needs to change. participate (25). Patients are more inclined to
When seeking control over their condition, search for information on the internet or obtain
patients value an emphatic and continuing information from psychiatrists, user support
therapeutic relationship with professionals (23). To groups, mental-health nurses and internet chat
improve patient treatment, patients should have rooms, than their pharmacist or GP (26). This
the opportunity to voice their expectations and to poses a problem as many patients with bipolar
participate in the decision-making process. There disorder are diagnosed and treated in a primary-
are four core issues that need to be considered care setting (21). In fact, as many as 90% of
when developing the treatment plan: communica- patients struggle to understand the complexity of
tion, flow and amount of information, patient bipolar disorder, whereas HCPs have the impres-
involvement in their treatment plan and the estab- sion that their patients are well educated and may
lishment of a trusting patient–HCP relationship. not see the need for improvement in information
provision on topics such as symptoms of bipolar
Communication. Listening to patients and disorder and their recognition, treatment
responding to their needs helps to break down the side-effects, treatment options, adherence issues,

15
Stafford and Colom

lifestyle and nutrition, and factors that improve have a written copy for their reference (29).
QoL (26). Receiving help with issues that are not Regular care reviews and adjustments of the care
directly related to medical treatment could improve plan are required to adapt to the changing needs of
the QoL of patients with bipolar disorder; however, the patient. However, a large proportion of
up to 50% of patients do not receive information patients with or without a care programme
about financial advice or benefits, and how to find approach do not have an annual review process
and keep work and accommodation (29). (29) or the opportunity to communicate with their
Questionnaires are often used to assess patient care coordinator before the review. Under such cir-
status and recovery. However, most of those cumstances, getting involved in their treatment is
questionnaires have been designed by psycholo- difficult, and therefore, patient inclusion and
gists, health service researchers, social scientists involvement needs to start at treatment outset.
and health economists, leaving little room for The National Association for Patient Participa-
patient input (30). In order to improve patient tion (NAPP) aims to introduce a Patient Participa-
experiences when being treated for any illness, it is tion Group in every GP practice based on the
of importance to establish priorities for patients mutual interests of the primary-care team and the
regarding their treatment and overall care, which is practice patients (www.napp.org.uk). NAPP encour-
a difficult task as patient priorities are subjective, ages patients to take responsibility for their own
change over time, and vary between trusts depend- health and that of their family and to join network-
ing on services provided, age, gender, and also type ing groups to exchange experiences locally, region-
of illness (27). In a European-wide study by the ally and on a national level. It further supports the
European Task Force on Patient Evaluations of development of forums in the community for
General Practice (EUROPEP), patients rated patients, carers and health service staff, and recog-
receiving a quick service in cases of urgent situa- nises the need to address serious health inequalities
tions as an absolute requirement of good general that persist across the United Kingdom. Through
care, along with the possibility of making appoint- the NAPP, patients can directly get involved in
ments within short notice under normal circum- influencing national policy debates and make their
stances, a GP who also provides adequate voice heard to ensure that the patient perspective is
information on the illness and on the diagnostic incorporated into commissioning decisions.
and treatment procedures necessary, and guaran-
tees confidentiality of the patient’s information. Relationship. A good patient–HCP relationship is
Furthermore, patients’ priorities include the fundamental to successful therapy. Factors that
following: a GP who is able to relieve symptoms can influence this relationship are a lack of interest
quickly; does not only cure diseases, but also offers in the patient’s point of view and a shortage of
services in order to prevent disease; is well specialist care, in particular, as patients report a
educated and attends courses regularly; takes time more satisfying relationship with a psychiatrist
to listen and gives the patient the feeling of being than a GP or mental-health nurse. Patients have
able to freely discuss problems; is willing to check high expectations when seeing a HCP, which are
health regularly; and the possibility of seeing the often disappointed at the first hurdle – the correct
same GP at each visit (27). diagnosis. Following incorrect diagnoses (38% of
patients are misdiagnosed for 4 years) – a ‘trial
Involvement. There is a need for greater patient and error’ method for finding adequate treatment
involvement in their personal treatment care plan, and facing a disconnect between patients and
as well as in the shaping of a more patient-oriented HCPs when it comes to advice on lifestyle choices
approach in overall care on a national level. and nutritional supplements – and estimation of
A staggering 55% of patients with bipolar disorder QoL, it is not surprising that relationships between
do not have a care plan; of the 45% that do, 17% HCPs and patients have not been the most trusting
do not understand it. This is partly due to patient in the past.
views not being taken into account; but, mainly, it Patient QoL is a subjective measure and there-
is due to the lack of patient education, which dis- fore needs to be evaluated on an individual basis.
ables them from participating in the preparation of There is controversy as to whether full recovery
a care plan. Patient involvement is further impeded from bipolar disorder is possible or whether QoL
by the preparation of a care plan that is removed is a measure of recovery and defined by the ability
from their needs and personal situation. Desired of the patient to manage ongoing symptoms.
patient behaviour in a crisis, setting of personal Therefore, the HCP should provide as much
goals and ways/services to achieve these are omitted support as possible to the patient to ensure that
from many care plans and many patients do not the patient experiences independence throughout

16
Psychoeducation in bipolar clinics

the treatment, but also has a contact in case of psychoeducation programmes are to empower the
emergency. Psychoeducation could provide the patient to understand bipolar disorder, to get
basis for a better understanding of the other actively involved in therapy planning and to be
person’s role during the treatment process and aware of methods of episode prevention/reduction.
acceptance of increased patient involvement. The development of bipolar clinics will improve
the access to psychoeducation and greatly assist in
achieving those aims.
Bipolar UK
Established in 1983, Bipolar UK is the only
Acknowledgements
national user-led charity in England and Wales
that specifically provides support for individuals The meeting on which this supplement is based was supported
whose lives are affected by bipolar disorder. This by Bristol-Myers Squibb, Uxbridge, UK. Editorial support for
the preparation of this manuscript was provided by Ogilvy
often misunderstood and devastating condition Healthworld Medical Education, London, UK; funding was
affects every aspect of life, and the charity aims to provided by Bristol-Myers Squibb. Nick Stafford would like to
help patients take control of their disorder and thank the Leicestershire Partnership NHS Trust for its continued
incorporate it into their daily routine. Services assistance and support in developing psychoeducation
offered by this independent charity include the programmes in Leicestershire and for their partnership working
with Bipolar UK in patient involvement programmes. Francesc
following: information about the disorder; guid- Colom would like to thank the support and funding of the Spanish
ance and publications; advocacy groups against Ministry of Health, Instituto de Salud Carlos III, CIBER-SAM.
discrimination; promoting social inclusion and the Dr Colom is also funded by the Spanish Ministry of Science and
rights of people affected by bipolar disorder; a Innovation, Instituto Carlos III, through a ‘Miguel Servet’
national network of self-help groups; a dedicated postdoctoral contract (CP08/00140) and a FIS (PS09/01044).
helpline for members of the charity; a self-manage-
ment training programme; an annual conference; a Declarations of interest
comprehensive website, including an e-community;
This manuscript is a result of a 1-day educational standalone
and the quarterly bipolar journal Pendulum. symposium sponsored with an unconditional educational grant
Furthermore, the charity is involved in projects by Bristol-Myers Squibb, who also sponsored this publication.
such as the Bipolar Link, which allows the charity Dr Nick Stafford has received honoraria, educational grants
to directly work with psychiatric units in Wales, and research funds from the following pharmaceutical compa-
and London Youth, a pilot project with direct nies: AstraZeneca, Otsuka, Bristol-Myers Squibb, Glaxo-
SmithKline, Pfizer Inc, Eli Lilly, Lundbeck, Servier
interactions with young people. The charity also Laboratories and GW Pharma. He owns a small publishing
seeks to combat the stigma and prejudice experi- house, My Mind Books Ltd, which publishes mental health and
enced by those affected by bipolar disorder. Cam- wellbeing books for the general public.
paigning for the improvement in patient services to Dr Francesc Colom has served as advisory or speaker for
promote recovery, providing a forum for members the following companies: Adamed, AstraZeneca, Bristol-
Myers Squibb, Eli Lilly, GlaxoSmithKline, Lundbeck,
to express their views and experiences, develop- MSD-Merck, Otsuka, Pfizer Inc, Sanofi-Aventis, Shire and
ment of partnerships with other organisations Tecnifar. He has received copyright fees from Cambridge
concerned with mental health, and education of University Press, Solal Ed., Ars Medica, Giovani Fioriti Ed.,
employers, HCPs and local communities about the Medipage, La Esfera de Los Libros, Morales i Torres Ed,
disorder are all important parts of this effort Panamericana, Mayo Ed. & Columna.
(http://www.bipolaruk.org.uk).
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