WESTERN MINDANAO STATE UNIVERSITY

EXTERNAL STUDIES UNIT- PAGADIAN CITY

Name: ______________________________________________________ Score: ___________

Year & Section: ____________________________ Date: ____________

Biochemistry: Molecules to Metabolism

2.1.1 Biochemostry explains living processes in terms of the chemical substances involved.
2.1.2 Carbon atoms can form four covalent bonds allowing a diversity of stable compounds to
exist.
2.1.3 Life is based on carbon compounds including carbohydrates, lipids, proteins and nucleic
acids.
2.1.4 Skill: Drawing molecular diagrams of glucose, ribose, a saturated fatty acid and a generalized 2.1.5 Skill: Identification of biochemicals such as sugars, lipids or amino acids from molecular
amino acid. (only the ring forms of D-ribose, alpha-D-glucose and beta-D-glucose are expected in diagrams.
drawings).
Identifying molecules:
*Draw each of the molecules in the table: Sugars: glucose is a 6-carbon ring, ribose & deoxyribose are 5-carbon rings

Organic compounds are the basis of life on Earth. Which compound is β-glucose Ribose Lipids: triglycerides (three fatty acid tails), phospholipids (phosphate & two fatty acid tails), steroids
(multiple ring-link structures), fatty acids (hydrocarbon chain – CH2)
life based on? ………………………………….
List the four types of biological molecules: Amino acids & Dipeptides: Look for nitrogen (N), amine group (NH2) and carboxyl group (COOH).
1. ………………………………….
In the table below, in each row there is one sugar, one lipid and on amino acid:
2. ………………………………….  Identify each molecule (specific names not required)
3. ………………………………….  Highlight/ annotate what allowed you to identify the molecule.

4. …………………………………. (we will cover this in the DNA topic)

Saturated Fatty Acid Generalized Amino Acid

Molecule: Molecule: Molecule:

……………………….. ……………………….. ………………………..
How did you know? How did you know? How did you know?
………………………… ………………………… …………………………
………………………… ………………………… …………………………
………………………… ………………………… …………………………
2.1.6 Metabolism is the web of all the enzyme-catalysed reactions in a cell or organism. 2.1.9 Application: Urea as an example of a compound that is produced by living organisms but can
2.1.7 Anabolism is the synthesis of complex molecules from simpler molecules including the also be artificially synthesized. ………………………… ………………………… …………………………
formation of macromolecules from monomers by condensation reactions.
2.1.8 Catabolism is the breakdown of complex molecules into simpler molecules including the
Use the words below to fill in the blanks in the paragraphs below.
hydrolysis of macromolecules into monomers.
kidneys protein organic vitalism

metabolic urea organic liver

Urea is produced by the ……………………….. breakdown of excess

……………………….. in the body. This occurs in the ……………………….. and the Molecule: Molecule: Molecule:
urea is filtered out of the blood by the ……………………….. ……………………….. ……………………….. ………………………..
How did you know? How did you know? How did you know?
Friedrich Wohler synthesized urea artificially. This was the first time that an ………………………… ………………………… …………………………
……………………….. compound had been synthesized artificially ………………………… …………………………
…………………………
………………………… ………………………… …………………………
In the diagram above, what does each “E” represent? …………………………………. The theory of ……………………….. is based on the idea that living organisms which
………………………… ………………………… …………………………
Metabolism is the web of all the enzyme-catalysed reactions in a cell or organism produce and are composed of ……………………….. macromolecules, that can only
be synthesized within the living organisms themselves due to some ‘vital force’.
Anabolic Reaction Catabolic Reactions
Wohlers synthesis of ……………………….. falsified this idea, as he made urea (an
Break down complex molecules
organic compound produced in the body) synthetically in the lab.
Molecule: Molecule:
Condensation reactions (removal of water) Explain it yourself:
……………………….. Molecule:
………………………………………………………………………………………………….. ………………………..
E.g. Respiration
How did you know? ………………………..
………………………………………………………………………………………………….. How did you know?
………………………… How did you know?
………………………………………………………………………………………………….. …………………………
 Monomers
Monosaccharides (e.g. glucose)
Multiple Choice
What feature of carbon makes it
most suitable as a basis for life?
A. Its abundance in nature
B. Its bonding properties
C. Its reactivity to light
D. Its presence in the early
atmosphere of the Earth
What characteristic shows that
this molecule is cholesterol?
A. It is made of carbon rings.
B. It has a very low proportion
of oxygen to carbon.
C. It contains OH groups as do
fatty acids.
D. It is made only of nitrogen,
oxygen and hydrogen.
2.1.1 Biochemistry explains living processes in terms of the chemical substances involved.
2.1.2 Carbon atoms can form four covalent bonds allowing a diversity of stable compounds to
exist.
2.1.3 Life is based on carbon compounds including carbohydrates, lipids, proteins and nucleic
acids
…………………………………………………………………………………………
…………………………………………………………………………………………
…………………………………………………………………………………………
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Macromolecules
…………………………………………………………………………………………………..
…………………………………………………………………………………………………..
…………………………………………………………………………………………………..
Proteins
Lipids
Short Structured
Which carbon compound produced by living Describe cell respiration in terms of metabolism. (2)
organisms is inorganic?
…………………………………………………………………………………………
…………………………………………………………………………………………
A. DNA
B. Cellulose …………………………………………………………………………………………
C. Glucose …………………………………………………………………………………………
D. Carbon dioxide
Distinguish between anabolism, catabolism and metabolism. (3)
Metabolism:………………………………………………………………………..…
……………………………………………………………………………………...…
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Anabolism:………………………….…………………………………………..…….
…………………………………………………………………………………………
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Catabolism……………………………………………………………………………
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Make your OWN Summary (key words, phrases, diagrams only)
2.1.4 Skill: Drawing molecular diagrams of glucose, ribose, a saturated fatty acid and a generalized
amino acid. (only the ring forms of D-ribose, alpha-D-glucose and beta-D-glucose are expected in
drawings).
β-glucose
Saturated Fatty Acid
………………………… ………………………… …………………………
………………………… ………………………… …………………………
………………………… ………………………… …………………………
…………………………
Extended Response
Explain how Friedrich Wohler’s synthesis of urea falsified the
theory of “vitalism”. (4)
How to answer the question:
Explain the theory of “vitalism”:
……………………………………………………………………………...
……………………………………………………………………………...
……………………………………………………………………………...
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What did Friedrich Wohler synthesise?
……………………………………………………………………………...
How is the substance that Friedrich Wohler made, usually made?
……………………………………………………………………………...
……………………………………………………………………………...
Link it all together – how did Friedrich Wohler disprove “vitalism”?
……………………………………………………………………………...
……………………………………………………………………………...
……………………………………………………………………………...
……………………………………………………………………………...
2.1.5 Skill: Identification of biochemicals such as sugars, lipids or amino acids from molecular
diagrams.
Make statement on how to identify each of the biochemicals mentioned in the objective.
Ribose
…………………………………………………………………………………………
…………………………………………………………………………………………
…………………………………………………………………………………………
…………………………………………………………………………………………
…………………………………………………………………………………………
Generalized Amino Acid
…………………………………………………………………………………………
…………………………………………………………………………………………
…………………………………………………………………………………………
2.1.6 Metabolism is the web of all the enzyme-catalysed reactions in a cell or organism. 2.1.9 Application: Urea as an example of a compound that is produced by living organisms but can …………………………………………………………………………………………
2.1.7 Anabolism is the synthesis of complex molecules from simpler molecules including the
also be artificially synthesized.
formation of macromolecules from monomers by condensation reactions. …………………………………………………………………………………………
2.1.8 Catabolism is the breakdown of complex molecules into simpler molecules including the …………………………………………………………………………………………
hydrolysis of macromolecules into monomers. …………………………………………………………………………………………
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