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List of enzymes

This page lists enzymes by their classification in the International Union of Biochemistry and Molecular
Biology's Enzyme Commission [EC] numbering system. For a list of the EC numbers themselves, see:

List of EC numbers (EC 1)


List of EC numbers (EC 2)
List of EC numbers (EC 3)
List of EC numbers (EC 4)
List of EC numbers (EC 5)
List of EC numbers (EC 6)

Contents
Category:Oxidoreductases (EC 1) (Oxidoreductase)
Category:EC 1.1 (act on the CH-OH group of donors)
Category:EC 1.2 (act on the aldehyde or oxo group of donors)
Category:EC 1.3 (act on the CH-CH group of donors)
Category:EC 1.4 (act on the CH-NH2 group of donors)
Category:EC 1.5 (act on CH-NH group of donors)
Category:EC 1.6 (act on NADH or NADPH)
Category:EC 1.7 (act on other nitrogenous compounds as donors)
Category:EC 1.8 (act on a sulfur group of donors)
Category:EC 1.9 (act on a heme group of donors)
Category:EC 1.10 (act on diphenols and related substances as donors)
Category:EC 1.11 (act on peroxide as an acceptor -- peroxidases)
Category:EC 1.12 (act on hydrogen as a donor)
Category:EC 1.13 (act on single donors with incorporation of molecular oxygen)
Category:EC 1.14 (act on paired donors with incorporation of molecular oxygen)
Category:EC 1.15 (act on superoxide radicals as acceptors)
Category:EC 1.16 (oxidize metal ions)
Category:EC 1.17 (act on CH or CH2 groups)
Category:EC 1.18 (act on iron-sulfur proteins as donors)
Category:EC 1.19 (act on reduced flavodoxin as donor)
Category:EC 1.20 (act on phosphorus or arsenic as donors)
Category:EC 1.21 (act on X-H and Y-H to form an X-Y bond)
Category:EC 1.97 (other oxidoreductases)
Category:Transferases (EC 2) (Transferase)
Category:EC 2.1 (transfer one-carbon groups, Methylase)
Category:EC 2.2 (transfer aldehyde or ketone groups)
Category:EC 2.3 (acyltransferases)
Category:EC 2.4 (glycosyltransferases)
Category:EC 2.5 (transfer alkyl or aryl groups, other than methyl groups)
Category:EC 2.6 (transfer nitrogenous groups)
Category:EC 2.7 (transfer phosphorus-containing groups)
Category:EC 2.8 (transfer sulfur-containing groups)
Category:EC 2.9 (transfer selenium-containing groups)
Category:Hydrolases (EC 3) (Hydrolase)
Category:EC 3.1 (act on ester bonds)
Category:EC 3.2 (act on sugars - glycosylases)
Category:EC 3.3 (act on ether bonds)
Category:EC 3.4 (act on peptide bonds - Peptidase)
Category:EC 3.5 (act on carbon-nitrogen bonds, other than peptide bonds)
Category:EC 3.6 (act on acid anhydrides)
Category:EC 3.7 (act on carbon-carbon bonds)
Category:EC 3.8 (act on halide bonds)
Category:EC 3.9 (act on phosphorus-nitrogen bonds)
Category:EC 3.10 (act on sulfur-nitrogen bonds)
Category:EC 3.11 (act on carbon-phosphorus bonds)
Category:EC 3.12 (act on sulfur-sulfur bonds)
Category:EC 3.13 (act on carbon-sulfur bonds)
Category:Lyases (EC 4) (Lyase)
Category:EC 4.1 (carbon-carbon lyases)
Category:EC 4.2 (carbon-oxygen lyases)
Category:EC 4.3 (carbon-nitrogen lyases)
Category:EC 4.4 (carbon-sulfur lyases)
Category:EC 4.5 (carbon-halide lyases)
Category:EC 4.6 (phosphorus-oxygen lyases)
Category:Isomerases (EC 5) (Isomerase)
Category:EC 5.1 (racemases and epimerases)
Category:EC 5.2 (cis-trans-isomerases)
Category:EC 5.3 (intramolecular oxidoreductases)
Category:EC 5.4 (intramolecular transferases -- mutases)
Category:EC 5.5 (intramolecular lyases)
Category:EC 5.99 (other isomerases)
Category:Ligases (EC 6) (Ligase)
Category:EC 6.1 (form carbon-oxygen bonds)
Category:EC 6.2 (form carbon-sulfur bonds)
Category:EC 6.3 (form carbon-nitrogen bonds)
Category:EC 6.4 (form carbon-carbon bonds)
Category:EC 6.5 (form phosphoric ester bonds)
Category:EC 6.6 (form nitrogen-metal bonds)

Category:Oxidoreductases (EC 1) (Oxidoreductase)


Dehydrogenase
Luciferase
DMSO reductase

Category:EC 1.1 (act on the CH-OH group of donors)


Category:EC 1.1.1 (with NAD+ or NADP+ as acceptor)
Alcohol dehydrogenase (NAD) EC 1.1.1.1 (https://enzyme.expasy.org/EC/1.1.1.1)
Alcohol dehydrogenase (NADP) EC 1.1.1.2 (https://enzyme.expasy.org/EC/1.1.1.2)
Homoserine dehydrogenase EC 1.1.1.3 (https://enzyme.expasy.org/EC/1.1.1.3)
Aminopropanol oxidoreductase EC 1.1.1.4 (https://enzyme.expasy.org/EC/1.1.1.4)
Diacetyl reductase EC 1.1.1.5 (https://enzyme.expasy.org/EC/1.1.1.5)
Glycerol dehydrogenase EC 1.1.1.6 (https://enzyme.expasy.org/EC/1.1.1.6)
Propanediol-phosphate dehydrogenase EC 1.1.1.7 (https://enzyme.expasy.org/EC/1.1.1.7)
glycerol-3-phosphate dehydrogenase (NAD+) EC 1.1.1.8 (https://enzyme.expasy.org/EC/1.
1.1.8)
D-xylulose reductase EC 1.1.1.9 (https://enzyme.expasy.org/EC/1.1.1.9)
L-xylulose reductase EC 1.1.1.10 (https://enzyme.expasy.org/EC/1.1.1.10)
Lactate dehydrogenase EC 1.1.1.27 (https://enzyme.expasy.org/EC/1.1.1.27)
Malate dehydrogenase EC 1.1.1.37 (https://enzyme.expasy.org/EC/1.1.1.37)
Isocitrate dehydrogenase EC 1.1.1.42 (https://enzyme.expasy.org/EC/1.1.1.42)
HMG-CoA reductase EC 1.1.1.88 (https://enzyme.expasy.org/EC/1.1.1.88)
Category:EC 1.1.2 (with a cytochrome as acceptor)
Category:EC 1.1.3 (with oxygen as acceptor)
Glucose oxidase EC 1.1.3.4 (https://enzyme.expasy.org/EC/1.1.3.4)
L-gulonolactone oxidase EC 1.1.3.8 (https://enzyme.expasy.org/EC/1.1.3.8)
Thiamine oxidase EC 1.1.3.23 (https://enzyme.expasy.org/EC/1.1.3.23)
Xanthine oxidase EC 1.1.3.32 (https://enzyme.expasy.org/EC/1.1.3.32)
Category:EC 1.1.4 (with a disulfide as acceptor)
Category:EC 1.1.5 (with a quinone or similar compound as acceptor)
Category:EC 1.1.99 (with other acceptors)

Category:EC 1.2 (act on the aldehyde or oxo group of donors)


Category:EC 1.2.1 (with NAD+ or NADP+ as acceptor)
Acetaldehyde dehydrogenase EC 1.2.1.10 (https://enzyme.expasy.org/EC/1.2.1.10)
Glyceraldehyde 3-phosphate dehydrogenase EC 1.2.1.12 (https://enzyme.expasy.org/EC/
1.2.1.12)
Pyruvate dehydrogenase EC 1.2.1.51 (https://enzyme.expasy.org/EC/1.2.1.51)
Category:EC 1.2.4
Oxoglutarate dehydrogenase EC 1.2.4.2 (https://enzyme.expasy.org/EC/1.2.4.2)

Category:EC 1.3 (act on the CH-CH group of donors)


Category:EC 1.3.1 (with NAD+ or NADP+ as acceptor)
Biliverdin reductase EC 1.3.1.24 (https://enzyme.expasy.org/EC/1.3.1.24)
Category:EC 1.3.2 (with a cytochrome as acceptor)
Category:EC 1.3.3 (with oxygen as acceptor)
Protoporphyrinogen oxidase EC 1.3.3.4 (https://enzyme.expasy.org/EC/1.3.3.4)
Category:EC 1.3.5 (with a quinone or similar compound as acceptor)
Category:EC 1.3.7 (with an iron-sulfur protein as acceptor)
Category:EC 1.3.99 (with other acceptors)

Category:EC 1.4 (act on the CH-NH2 group of donors)


Category:EC 1.4.3
Monoamine oxidase EC 1.4.3.4 (https://enzyme.expasy.org/EC/1.4.3.4)

Category:EC 1.5 (act on CH-NH group of donors)


Category:EC 1.5.1 (with NAD+ or NADP+ as acceptor)
Dihydrofolate reductase EC 1.5.1.3 (https://enzyme.expasy.org/EC/1.5.1.3)
Methylenetetrahydrofolate reductase EC 1.5.1.20 (https://enzyme.expasy.org/EC/1.5.1.20)
Category:EC 1.5.3 (with oxygen as acceptor)
Sarcosine oxidase EC 1.5.3.1 (https://enzyme.expasy.org/EC/1.5.3.1)
Dihydrobenzophenanthridine oxidase EC 1.5.3.12 (https://enzyme.expasy.org/EC/1.5.3.12)
Category:EC 1.5.4 (with a disulfide as acceptor)
Category:EC 1.5.5 (with a quinone or similar compound as acceptor)
Category:EC 1.5.7 (with an iron-sulfur protein as acceptor)
Category:EC 1.5.8 (with a flavin as acceptor)
Category:EC 1.5.99 (with other acceptors)

Category:EC 1.6 (act on NADH or NADPH)


Category:EC 1.6.1 (with NAD+ or NADP+ as acceptor)
Category:EC 1.6.2 (with a cytochrome as acceptor)
Category:EC 1.6.3 (with oxygen as acceptor)
Category:EC 1.6.4 now Category:EC 1.8.1
Category:EC 1.6.5 (with a quinone or similar compound as acceptor)
NADH dehydrogenase EC 1.6.5.3 (https://enzyme.expasy.org/EC/1.6.5.3)
Category:EC 1.6.6 (with a nitrogenous group as acceptor)
Category:EC 1.6.7 now Category:EC 1.18.1
Category:EC 1.6.8 now Category:EC 1.5.1
Category:EC 1.6.99 (with other acceptors)

Category:EC 1.7 (act on other nitrogenous compounds as donors)


Category:EC 1.7.1 (with NAD+ or NADP+ as acceptor)
Category:EC 1.7.2 (with a cytochrome as acceptor)
Category:EC 1.7.3 (with oxygen as acceptor)
Urate oxidase EC 1.7.3.3 (https://enzyme.expasy.org/EC/1.7.3.3)
Category:EC 1.7.7 (with an iron-sulfur protein as acceptor)
Category:EC 1.7.99 (with other acceptors)
Nitrite reductase EC 1.7.99.3 (https://enzyme.expasy.org/EC/1.7.99.3)
Nitrate reductase EC 1.7.99.4 (https://enzyme.expasy.org/EC/1.7.99.4)

Category:EC 1.8 (act on a sulfur group of donors)


Category:EC 1.8.1 (with NAD+ or NADP+ as acceptor)
Glutathione reductase EC 1.8.1.7 (https://enzyme.expasy.org/EC/1.8.1.7)
Thioredoxin reductase EC 1.8.1.9 (https://enzyme.expasy.org/EC/1.8.1.9)
Category:EC 1.8.2 (with a cytochrome as acceptor)
Category:EC 1.8.3 (with oxygen as acceptor)
Sulfite oxidase EC 1.8.3.1 (https://enzyme.expasy.org/EC/1.8.3.1)
Category:EC 1.8.4 (with a disulfide as acceptor)
Category:EC 1.8.5 (with a quinone or similar compound as acceptor)
Category:EC 1.8.6 deleted, included in EC 2.5.1.18
Category:EC 1.8.7 (with an iron-sulfur protein as acceptor)
Category:EC 1.8.98 (with other, known, acceptors)
Category:EC 1.8.99 (with other acceptors)

Category:EC 1.9 (act on a heme group of donors)


Category:EC 1.9.3 (with oxygen as acceptor)
Cytochrome c oxidase EC 1.9.3.1 (https://enzyme.expasy.org/EC/1.9.3.1)
Category:EC 1.9.6 (with a nitrogenous as acceptor)
Category:EC 1.9.99 transferred, now EC 1.9.98.1

Category:EC 1.10 (act on diphenols and related substances as donors)


Category:EC 1.10.1(with NAD+ or NADP+ as acceptor)
Category:EC 1.10.2 (with a cytochrome as acceptor)
Coenzyme Q - cytochrome c reductase EC 1.10.2.2 (https://enzyme.expasy.org/EC/1.10.2.
2)
Category:EC 1.10.3 (with oxygen as acceptor)
Catechol oxidase EC 1.10.3.1 (https://enzyme.expasy.org/EC/1.10.3.1)
Laccase EC 1.10.3.2 (https://enzyme.expasy.org/EC/1.10.3.2)
Category:EC 1.10.99 (with other acceptors)
Category:EC 1.11 (act on peroxide as an acceptor -- peroxidases)
Category:EC 1.11.1 (peroxidases)
Cytochrome c peroxidase EC 1.11.1.5 (https://enzyme.expasy.org/EC/1.11.1.5)
Catalase EC 1.11.1.6 (https://enzyme.expasy.org/EC/1.11.1.6)
Myeloperoxidase EC 1.11.1.7 (https://enzyme.expasy.org/EC/1.11.1.7)
Thyroid peroxidase EC 1.11.1.8 (https://enzyme.expasy.org/EC/1.11.1.8)
Glutathione peroxidase EC 1.11.1.9 (https://enzyme.expasy.org/EC/1.11.1.9)

Category:EC 1.12 (act on hydrogen as a donor)


Category:EC 1.12.1 (with NAD+ or NADP+ as acceptor)
Category:EC 1.12.2 (with a cytochrome as acceptor)
Category:EC 1.12.5 (with a quinone or similar compound as acceptor)
Category:EC 1.12.7 (with an iron-sulfur protein as acceptor)
Category:EC 1.12.98 (with other known acceptors)
Category:EC 1.12.99 (with other acceptors)

Category:EC 1.13 (act on single donors with incorporation of molecular


oxygen)
Category:EC 1.13.11 (With incorporation of two atoms of oxygen)
4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27 (https://enzyme.expasy.org/EC/1.1
3.11.27))
Category:EC 1.13.12 (With incorporation of one atom of oxygen (internal monooxygenases or
internal mixed function oxidases))
Renilla-luciferin 2-monooxygenase EC 1.13.12.5 (https://enzyme.expasy.org/EC/1.13.12.5)
Cypridina-luciferin 2-monooxygenase EC 1.13.12.6 (https://enzyme.expasy.org/EC/1.13.1
2.6)
Firefly luciferase EC 1.13.12.7 (https://enzyme.expasy.org/EC/1.13.12.7)
Watasenia-luciferin 2-monooxygenase EC 1.13.12.8 (https://enzyme.expasy.org/EC/1.13.1
2.8)
Oplophorus-luciferin 2-monooxygenase EC 1.13.12.13 (https://enzyme.expasy.org/EC/1.1
3.12.13)

Category:EC 1.14 (act on paired donors with incorporation of molecular


oxygen)
Cytochrome P450 oxidase
Category:Cytochrome P450
Aromatase EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
CYP2D6 EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
CYP2E1 EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
CYP3A4 EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
Cytochrome P450 oxidase
Category:EC 1.14.12
Nitric oxide dioxygenase
Category:EC 1.14.13
Nitric oxide synthase EC 1.14.13.39 (https://enzyme.expasy.org/EC/1.14.13.39)
Category:EC 1.14.14
Aromatase EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
CYP2D6 EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
CYP2E1 EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
CYP3A4 EC 1.14.14.1 (https://enzyme.expasy.org/EC/1.14.14.1)
Category:EC 1.14.16
Phenylalanine hydroxylase EC 1.14.16.1 (https://enzyme.expasy.org/EC/1.14.16.1)
Category:EC 1.14.18
Tyrosinase EC 1.14.18.1 (https://enzyme.expasy.org/EC/1.14.18.1)

Category:EC 1.15 (act on superoxide radicals as acceptors)


Category:EC 1.15.1
Superoxide dismutase EC 1.15.1.1 (https://enzyme.expasy.org/EC/1.15.1.1)

Category:EC 1.16 (oxidize metal ions)


Category:EC 1.16.3
Ceruloplasmin EC 1.16.3.1 (https://enzyme.expasy.org/EC/1.16.3.1)

Category:EC 1.17 (act on CH or CH2 groups)


Category:EC 1.17.1
Leucoanthocyanidin reductase EC 1.17.1.3 (https://enzyme.expasy.org/EC/1.17.1.3)
Xanthine dehydrogenase EC 1.17.1.4 (https://enzyme.expasy.org/EC/1.17.1.4)
Nicotinate dehydrogenase EC 1.17.1.5 (https://enzyme.expasy.org/EC/1.17.1.5)
4-hydroxy-tetrahydrodipicolinate reductase EC 1.17.1.8 (https://enzyme.expasy.org/EC/1.1
7.1.8)
Category:EC 1.17.2
Nicotinate dehydrogenase (cytochrome) EC 1.17.2.1 (https://enzyme.expasy.org/EC/1.17.
2.1)
Category:EC 1.17.3
Xanthine oxidase EC 1.17.3.2 (https://enzyme.expasy.org/EC/1.17.3.2)
Category:EC 1.17.4
Ribonucleotide reductase EC 1.17.4.1 (https://enzyme.expasy.org/EC/1.17.4.1)
Ribonucleoside-triphosphate reductase EC 1.17.4.2 (https://enzyme.expasy.org/EC/1.17.4.
2)
Vitamin K epoxide reductase
Vitamin-K-epoxide reductase (warfarin-sensitive) EC 1.17.4.4 (https://enzyme.expasy.org/E
C/1.17.4.4)
Vitamin-K-epoxide reductase (warfarin-insensitive) EC 1.17.4.5 (https://enzyme.expasy.or
g/EC/1.17.4.5)
RRM1
RRM2
RRM2B
Category:EC 1.17.5
Caffeine dehydrogenase EC 1.17.5.2 (https://enzyme.expasy.org/EC/1.17.5.2)
Category:EC 1.17.7
Category:EC 1.17.99

Category:EC 1.18 (act on iron-sulfur proteins as donors)


Category:EC 1.18.6
Nitrogenase EC 1.18.6.1 (https://enzyme.expasy.org/EC/1.18.6.1)

Category:EC 1.19 (act on reduced flavodoxin as donor)


Category:EC 1.19.6
Nitrogenase (flavodoxin) EC 1.19.6.1 (https://enzyme.expasy.org/EC/1.19.6.1)

Category:EC 1.20 (act on phosphorus or arsenic as donors)


Category:EC 1.20.1
Category:EC 1.20.2
Category:EC 1.20.4
Arsenate reductase (glutaredoxin) EC 1.20.4.1 (https://enzyme.expasy.org/EC/1.20.4.1)
Glutaredoxin
Category:EC 1.20.9
Category:EC 1.20.99

Category:EC 1.21 (act on X-H and Y-H to form an X-Y bond)


Category:EC 1.21.1
Iodotyrosine deiodinase EC 1.21.1.1 (https://enzyme.expasy.org/EC/1.21.1.1)
Category:EC 1.21.3
Isopenicillin N synthase EC 1.21.3.1 (https://enzyme.expasy.org/EC/1.21.3.1)
Tetrahydrocannabinolic acid synthase EC 1.21.3.7 (https://enzyme.expasy.org/EC/1.21.3.7)
Category:EC 1.21.4
Category:EC 1.21.99
Thyroxine 5-deiodinase EC 1.21.99.3 (https://enzyme.expasy.org/EC/1.21.99.3)
Iodothyronine deiodinase EC 1.21.99.3 (https://enzyme.expasy.org/EC/1.21.99.3) and EC
1.21.99.4 (https://enzyme.expasy.org/EC/1.21.99.4)

Category:EC 1.97 (other oxidoreductases)


Category:EC 1.97.1
Deiodinase EC 1.97.1.10 (https://enzyme.expasy.org/EC/1.97.1.10)

Category:Transferases (EC 2) (Transferase)


Glutathione S-transferase

Category:EC 2.1 (transfer one-carbon groups, Methylase)


Category:EC 2.1.1
Catechol-O-methyl transferase EC 2.1.1.6 (https://enzyme.expasy.org/EC/2.1.1.6)
DNA methyltransferase EC 2.1.1.72 (https://enzyme.expasy.org/EC/2.1.1.72), EC
2.1.1.113 (https://enzyme.expasy.org/EC/2.1.1.113), EC 2.1.1.37 (https://enzyme.expasy.or
g/EC/2.1.1.37)
Histone methyltransferase EC 2.1.1.43 (https://enzyme.expasy.org/EC/2.1.1.43), EC
2.1.1.125 (https://enzyme.expasy.org/EC/2.1.1.125)
Category:EC 2.1.3
Aspartate transcarbamoylase EC 2.1.3.2 (https://enzyme.expasy.org/EC/2.1.3.2)
Ornithine transcarbamoylase EC 2.1.3.3 (https://enzyme.expasy.org/EC/2.1.3.3)

Category:EC 2.2 (transfer aldehyde or ketone groups)


Category:EC 2.2.1
Transketolase EC 2.2.1.1 (https://enzyme.expasy.org/EC/2.2.1.1)
Transaldolase EC 2.2.1.2 (https://enzyme.expasy.org/EC/2.2.1.2)
Acetolactate synthase EC 2.2.1.6 (https://enzyme.expasy.org/EC/2.2.1.6)
2-Succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase EC 2.2.1.9
(https://enzyme.expasy.org/EC/2.2.1.9)

Category:EC 2.3 (acyltransferases)


Category:EC 2.3.1
Aminolevulinic acid synthase EC 2.3.1.37 (https://enzyme.expasy.org/EC/2.3.1.37)
Choline acetyltransferase EC 2.3.1.6 (https://enzyme.expasy.org/EC/2.3.1.6)
Category:EC 2.3.2
Factor XIII EC 2.3.2.13 (https://enzyme.expasy.org/EC/2.3.2.13)
Gamma glutamyl transpeptidase EC 2.3.2.2 (https://enzyme.expasy.org/EC/2.3.2.2)
Transglutaminase EC 2.3.2.13 (https://enzyme.expasy.org/EC/2.3.2.13)

Category:EC 2.4 (glycosyltransferases)


Category:EC 2.4.2
Hypoxanthine-guanine phosphoribosyltransferase EC 2.4.2.8 (https://enzyme.expasy.org/E
C/2.4.2.8)

Category:EC 2.5

Category:EC 2.5.1
Thiaminase EC 2.5.1.2 (https://enzyme.expasy.org/EC/2.5.1.2)

Category:EC 2.5 (transfer alkyl or aryl groups, other than methyl groups)

Flavin prenyltransferase EC 2.5.1.129 (https://enzyme.expasy.org/EC/2.5.1.129)

Category:EC 2.6 (transfer nitrogenous groups)


Category:EC 2.6.1
Alanine transaminase EC 2.6.1.2 (https://enzyme.expasy.org/EC/2.6.1.2)
Aspartate transaminase EC 2.6.1.1 (https://enzyme.expasy.org/EC/2.6.1.1)

Category:EC 2.7 (transfer phosphorus-containing groups)


Category:EC 2.7.2
Butyrate kinase (EC 2.7.2.7 (https://enzyme.expasy.org/EC/2.7.2.7))

Category:EC 2.8 (transfer sulfur-containing groups)


EC 2.8.1.1 (https://enzyme.expasy.org/EC/2.8.1.1): Thiosulfate sulfurtransferase
EC 2.8.1.2 (https://enzyme.expasy.org/EC/2.8.1.2): 3-mercaptopyruvate sulfurtransferase
EC 2.8.1.3 (https://enzyme.expasy.org/EC/2.8.1.3): Thiosulfate--thiol sulfurtransferase
EC 2.8.1.4 (https://enzyme.expasy.org/EC/2.8.1.4): tRNA uracil 4-sulfurtransferase
EC 2.8.1.5 (https://enzyme.expasy.org/EC/2.8.1.5): Thiosulfate--dithiol sulfurtransferase
EC 2.8.1.6 (https://enzyme.expasy.org/EC/2.8.1.6): Biotin synthase
EC 2.8.1.7 (https://enzyme.expasy.org/EC/2.8.1.7): Cysteine desulfurase
EC 2.8.1.8 (https://enzyme.expasy.org/EC/2.8.1.8): Lipoyl synthase
EC 2.8.1.9 (https://enzyme.expasy.org/EC/2.8.1.9): Molybdenum cofactor sulfurtransferase
EC 2.8.1.10 (https://enzyme.expasy.org/EC/2.8.1.10): Thiazole synthase
EC 2.8.1.11 (https://enzyme.expasy.org/EC/2.8.1.11): Molybdopterin synthase
sulfurtransferase
EC 2.8.1.12 (https://enzyme.expasy.org/EC/2.8.1.12): Molybdopterin synthase
EC 2.8.1.13 (https://enzyme.expasy.org/EC/2.8.1.13): tRNA-uridine 2-sulfurtransferase
EC 2.8.1.14 (https://enzyme.expasy.org/EC/2.8.1.14): tRNA-5-taurinomethyluridine 2-
sulfurtransferase
EC 2.8.1.15 (https://enzyme.expasy.org/EC/2.8.1.15): tRNA-5-methyluridine(54) 2-
sulfurtransferase

Category:EC 2.9 (transfer selenium-containing groups)


EC 2.9.1.1 (https://enzyme.expasy.org/EC/2.9.1.1): L-seryl-tRNA(Sec) selenium transferase
EC 2.9.1.2 (https://enzyme.expasy.org/EC/2.9.1.2): O-phospho-L-seryl-tRNA(Sec):L-
selenocysteinyl-tRNA synthase

Category:Hydrolases (EC 3) (Hydrolase)


Hydrolytic enzyme

Category:EC 3.1 (act on ester bonds)


Nuclease
Endonuclease
Exonuclease
Category:EC 3.1.1
Acid hydrolase
Phospholipase A (EC 3.1.1.4 (https://enzyme.expasy.org/EC/3.1.1.4))
Acetylcholinesterase (EC 3.1.1.7 (https://enzyme.expasy.org/EC/3.1.1.7))
Cholinesterase (EC 3.1.1.8 (https://enzyme.expasy.org/EC/3.1.1.8))
Lipoprotein lipase (EC 3.1.1.34 (https://enzyme.expasy.org/EC/3.1.1.34))
Category:EC 3.1.2
Ubiquitin carboxy-terminal hydrolase L1 (EC 3.1.2.15 (https://enzyme.expasy.org/EC/3.1.2.
15))
Category:EC 3.1.3
Phosphatase
Alkaline phosphatase (EC 3.1.3.1 (https://enzyme.expasy.org/EC/3.1.3.1))
Fructose bisphosphatase (EC 3.1.3.11 (https://enzyme.expasy.org/EC/3.1.3.11))
Category:EC 3.1.4
Phospholipase C (EC 3.1.4.3 (https://enzyme.expasy.org/EC/3.1.4.3))
CGMP specific phosphodiesterase type 5 (EC 3.1.4.17 (https://enzyme.expasy.org/EC/3.1.
4.17))
Phospholipase D (EC 3.1.4.50 (https://enzyme.expasy.org/EC/3.1.4.50))
Category:EC 3.1.21
Restriction enzyme Type 1 (EC 3.1.21.3 (https://enzyme.expasy.org/EC/3.1.21.3))
Restriction enzyme Type 2 (EC 3.1.21.4 (https://enzyme.expasy.org/EC/3.1.21.4))
Restriction enzyme Type 3 (EC 3.1.21.5 (https://enzyme.expasy.org/EC/3.1.21.5))
Restriction enzyme Type 4 (?)
Deoxyribonuclease I (EC 3.1.21.1 (https://enzyme.expasy.org/EC/3.1.21.1))
Category:EC 3.1.26
RNase H (EC 3.1.26.4 (https://enzyme.expasy.org/EC/3.1.26.4))
Category:EC 3.1.27
Ribonuclease

Category:EC 3.2 (act on sugars - glycosylases)


Category:EC 3.2.1
Amylase (EC 3.2.1.1 (https://enzyme.expasy.org/EC/3.2.1.1))
Sucrase (EC 3.2.1.10 (https://enzyme.expasy.org/EC/3.2.1.10))
Chitinase (EC 3.2.1.14 (https://enzyme.expasy.org/EC/3.2.1.14))
Lysozyme (EC 3.2.1.17 (https://enzyme.expasy.org/EC/3.2.1.17))
Maltase (EC 3.2.1.20 (https://enzyme.expasy.org/EC/3.2.1.20))
Lactase (EC 3.2.1.23 (https://enzyme.expasy.org/EC/3.2.1.23))
Beta-galactosidase (EC 3.2.1.23 (https://enzyme.expasy.org/EC/3.2.1.23))
Hyaluronidase (EC 3.2.1.35 (https://enzyme.expasy.org/EC/3.2.1.35))

Category:EC 3.3 (act on ether bonds)


Category:EC 3.3
Adenosylmethionine hydrolase
S-adenosyl-L-homocysteine hydrolase
Alkenylglycerophosphocholine hydrolase
Alkenylglycerophosphoethanolamine hydrolase
Cholesterol-5,6-oxide hydrolase
Hepoxilin-epoxide hydrolase
Isochorismatase
Leukotriene-A4 hydrolase
Limonene-1,2-epoxide hydrolase
Microsomal epoxide hydrolase
Trans-epoxysuccinate hydrolase

Category:EC 3.4 (act on peptide bonds - Peptidase)


Category:EC 3.4.11
Alanine aminopeptidase
Category:EC 3.4.15
Angiotensin converting enzyme
Category:EC 3.4.21
Serine protease
Chymotrypsin (EC 3.4.21.1 (https://enzyme.expasy.org/EC/3.4.21.1))
Trypsin (EC 3.4.21.4 (https://enzyme.expasy.org/EC/3.4.21.4))
Thrombin (EC 3.4.21.5 (https://enzyme.expasy.org/EC/3.4.21.5))
Factor X (EC 3.4.21.6 (https://enzyme.expasy.org/EC/3.4.21.6))
Plasmin (EC 3.4.21.7 (https://enzyme.expasy.org/EC/3.4.21.7))
Acrosin (EC 3.4.21.10 (https://enzyme.expasy.org/EC/3.4.21.10))
Factor VII (EC 3.4.21.21 (https://enzyme.expasy.org/EC/3.4.21.21))
Factor IX (EC 3.4.21.22 (https://enzyme.expasy.org/EC/3.4.21.22))
Prolyl oligopeptidase (EC 3.4.21.26 (https://enzyme.expasy.org/EC/3.4.21.26))
Factor XI (EC 3.4.21.27 (https://enzyme.expasy.org/EC/3.4.21.27))
Elastase (EC 3.4.21.37 (https://enzyme.expasy.org/EC/3.4.21.37))
Factor XII (EC 3.4.21.38 (https://enzyme.expasy.org/EC/3.4.21.38))
Proteinase K (EC 3.4.21.64 (https://enzyme.expasy.org/EC/3.4.21.64))
Tissue plasminogen activator (EC 3.4.21.68 (https://enzyme.expasy.org/EC/3.4.21.68))
Protein C (EC 3.4.21.69 (https://enzyme.expasy.org/EC/3.4.21.69))
Category:EC 3.4.22
Separase (EC 3.4.22.49 (https://enzyme.expasy.org/EC/3.4.22.49))
Category:EC 3.4.23
Pepsin (EC 3.4.23.1 (https://enzyme.expasy.org/EC/3.4.23.1))
Rennet (EC 3.4.23.4 (https://enzyme.expasy.org/EC/3.4.23.4))
Renin (EC 3.4.23.15 (https://enzyme.expasy.org/EC/3.4.23.15))
Trypsinogen (EC 3.4.23.18 (https://enzyme.expasy.org/EC/3.4.23.18)) and
(20/21/23/24/26)
Plasmepsin (EC 3.4.23.39 (https://enzyme.expasy.org/EC/3.4.23.39))
Category:EC 3.4.24
Matrix metalloproteinase (EC 3.4.24.7 (https://enzyme.expasy.org/EC/3.4.24.7))
Category:EC 3.4.25
Metalloendopeptidase

Category:EC 3.5 (act on carbon-nitrogen bonds, other than peptide bonds)


Category:EC 3.5.1 (In linear amides)
Urease (EC 3.5.1.5 (https://enzyme.expasy.org/EC/3.5.1.5))
Category:EC 3.5.2 (In cyclic amides)
Beta-lactamase (EC 3.5.2.6 (https://enzyme.expasy.org/EC/3.5.2.6))
Category:EC 3.5.3 (In linear amidines)
Arginase (EC 3.5.3.1 (https://enzyme.expasy.org/EC/3.5.3.1))
Category:EC 3.5.4 (In cyclic amidines)
Adenosine deaminase (EC 3.5.4.4 (https://enzyme.expasy.org/EC/3.5.4.4))
GTP cyclohydrolase I (EC 3.5.4.16 (https://enzyme.expasy.org/EC/3.5.4.16))
Category:EC 3.5.5 (In nitriles)
Nitrilase (EC 3.5.5.1 (https://enzyme.expasy.org/EC/3.5.5.1))
Category:EC 3.6 (act on acid anhydrides)
Category:EC 3.6.1
Helicase
DnaB helicase
RecQ helicase
Category:EC 3.6.3
ATPase
NaKATPase (EC 3.6.3.9 (https://enzyme.expasy.org/EC/3.6.3.9))
ATP synthase (EC 3.6.3.14 (https://enzyme.expasy.org/EC/3.6.3.14))

Category:EC 3.7 (act on carbon-carbon bonds)


Kynureninase EC 3.7.1.3 (https://enzyme.expasy.org/EC/3.7.1.3)

Category:EC 3.8 (act on halide bonds)


EC 3.8.1.3 Haloacetate dehalogenase

Category:EC 3.9 (act on phosphorus-nitrogen bonds)


EC 3.9.1.1 (https://enzyme.expasy.org/EC/3.9.1.1): Phosphoamidase
EC 3.9.1.2 (https://enzyme.expasy.org/EC/3.9.1.2): Protein arginine phosphatase
EC 3.9.1.3 (https://enzyme.expasy.org/EC/3.9.1.3): Phosphohistidine phosphatase

Category:EC 3.10 (act on sulfur-nitrogen bonds)


EC 3.10.1.1 (https://enzyme.expasy.org/EC/3.10.1.1): N-sulfoglucosamine sulfohydrolase
EC 3.10.1.2 (https://enzyme.expasy.org/EC/3.10.1.2): Cyclamate sulfohydrolase

Category:EC 3.11 (act on carbon-phosphorus bonds)


EC 3.11.1.1 (https://enzyme.expasy.org/EC/3.11.1.1): Phosphonoacetaldehyde hydrolase
EC 3.11.1.2 (https://enzyme.expasy.org/EC/3.11.1.2): Phosphonoacetate hydrolase
EC 3.11.1.3 (https://enzyme.expasy.org/EC/3.11.1.3): Phosphonopyruvate hydrolase

Category:EC 3.12 (act on sulfur-sulfur bonds)


EC 3.12.1.1 (https://enzyme.expasy.org/EC/3.12.1.1): Trithionate hydrolase

Category:EC 3.13 (act on carbon-sulfur bonds)


EC 3.13.1.1 (https://enzyme.expasy.org/EC/3.13.1.1): UDP-sulfoquinovose synthase
EC 3.13.1.3 (https://enzyme.expasy.org/EC/3.13.1.3): 2'-hydroxybiphenyl-2-sulfinate
desulfinase
EC 3.13.1.4 (https://enzyme.expasy.org/EC/3.13.1.4): 3-sulfinopropanoyl-CoA desulfinase
EC 3.13.1.5 (https://enzyme.expasy.org/EC/3.13.1.5): Carbon disulfide hydrolase
EC 3.13.1.6 (https://enzyme.expasy.org/EC/3.13.1.6): (CysO sulfur-carrier protein)-S-L-
cysteine hydrolase
EC 3.13.1.7 (https://enzyme.expasy.org/EC/3.13.1.7): Carbonyl sulfide hydrolase
EC 3.13.1.8 (https://enzyme.expasy.org/EC/3.13.1.8): S-adenosyl-L-methionine hydrolase
(adenosine-forming)

Category:Lyases (EC 4) (Lyase)

Category:EC 4.1 (carbon-carbon lyases)


Category:EC 4.1.1
Ornithine decarboxylase (EC 4.1.1.17 (https://enzyme.expasy.org/EC/4.1.1.17))
Uridine monophosphate synthetase (EC 4.1.1.23 (https://enzyme.expasy.org/EC/4.1.1.23))
Aromatic-L-amino-acid decarboxylase (EC 4.1.1.28 (https://enzyme.expasy.org/EC/4.1.1.2
8))
RubisCO (EC 4.1.1.39 (https://enzyme.expasy.org/EC/4.1.1.39))
Category:EC 4.1.2
Fructose-bisphosphate aldolase (EC 4.1.2.13 (https://enzyme.expasy.org/EC/4.1.2.13))

Category:EC 4.2 (carbon-oxygen lyases)


Category:EC 4.2.1
Carbonic anhydrase (EC 4.2.1.1 (https://enzyme.expasy.org/EC/4.2.1.1))
Tryptophan synthase (EC 4.2.1.20 (https://enzyme.expasy.org/EC/4.2.1.20))

Category:EC 4.3 (carbon-nitrogen lyases)


Category:EC 4.3.1
Phenylalanine ammonia-lyase (EC 4.3.1.24 (https://enzyme.expasy.org/EC/4.3.1.24))

Category:EC 4.4 (carbon-sulfur lyases)


Category:EC 4.4.1
Cystathionine gamma-lyase
Cystathionine beta-lyase
Leukotriene C4 synthase

Category:EC 4.5 (carbon-halide lyases)


Category:EC 4.5.1
Dichloromethane dehalogenase
Halohydrin dehalogenase

Category:EC 4.6 (phosphorus-oxygen lyases)


Category:EC 4.6.1
Adenylate cyclase (EC 4.6.1.1 (https://enzyme.expasy.org/EC/4.6.1.1))
Guanylate cyclase (EC 4.6.1.2 (https://enzyme.expasy.org/EC/4.6.1.2))

Category:Isomerases (EC 5) (Isomerase)

Category:EC 5.1 (racemases and epimerases)


Category:EC 5.1.1
Amino-acid racemase: Phenylalanine racemase (ATP-hydrolysing)
Serine racemase
Category:EC 5.1.2
Mandelate racemase
Category:EC 5.1.3
UDP-glucose 4-epimerase
Category:EC 5.1.99
Methylmalonyl CoA epimerase

Category:EC 5.2 (cis-trans-isomerases)


Category:EC 5.2
FKBP: FKBP1A
FKBP1B
FKBP2
FKBP3
FKBP5
FKBP6
FKBP8
FKBP9
FKBP10
FKBP52
FKBPL
Cyclophilin
Parvulin
Prolyl isomerase
2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
Beta-carotene isomerase
Farnesol 2-isomerase
Furylfuramide isomerase
Linoleate isomerase
Maleate isomerase
Maleylacetoacetate isomerase
Maleylpyruvate isomerase
Parvulin
Photoisomerase
Prolycopene isomerase
Prolyl isomerase
Retinal isomerase
Retinol isomerase
Zeta-carotene isomerase

Category:EC 5.3 (intramolecular oxidoreductases)


Category:EC 5.3.3
Enoyl CoA isomerase (EC 5.3.3.8 (https://enzyme.expasy.org/EC/5.3.3.8))
Category:EC 5.3.4
Protein disulfide isomerase (EC 5.3.4.1 (https://enzyme.expasy.org/EC/5.3.4.1))

Category:EC 5.4 (intramolecular transferases -- mutases)


Category:EC 5.4.2
Phosphoglucomutase (EC 5.4.2.2 (https://enzyme.expasy.org/EC/5.4.2.2))

Category:EC 5.5 (intramolecular lyases)


Intramolecular lyases:
EC number Examples
EC 5.5.1.1 Muconate cycloisomerase
EC 5.5.1.2 3-carboxy-cis,cis-muconate cycloisomerase
EC 5.5.1.3 Tetrahydroxypteridine cycloisomerase
EC 5.5.1.4 Inositol-3-phosphate synthase
EC 5.5.1.5 Carboxy-cis,cis-muconate cyclase
EC 5.5.1.6 Chalcone isomerase
EC 5.5.1.7 Chloromuconate cycloisomerase
EC 5.5.1.8 (+)-bornyl diphosphate synthase
EC 5.5.1.9 Cycloeucalenol cycloisomerase
EC 5.5.1.10 Alpha-pinene-oxide decyclase
EC 5.5.1.11 Dichloromuconate cycloisomerase
EC 5.5.1.12 Copalyl diphosphate synthase
EC 5.5.1.13 Ent-copalyl diphosphate synthase
EC 5.5.1.14 Syn-copalyl-diphosphate synthase
EC 5.5.1.15 Terpentedienyl-diphosphate synthase
EC 5.5.1.16 Halimadienyl-diphosphate synthase
EC 5.5.1.17 (S)-beta-macrocarpene synthase
EC 5.5.1.18 Lycopene epsilon-cyclase
EC 5.5.1.19 Lycopene beta-cyclase
EC 5.5.1.20 Prosolanapyrone-III cycloisomerase
EC 5.5.1.n1 D-ribose pyranase
EC 5.5.1.22 Steroid Delta Isomerase

Category:EC 5.99 (other isomerases)


Category:EC 5.99.1
Topoisomerase (type I: EC 5.99.1.2 (https://enzyme.expasy.org/EC/5.99.1.2), type II: EC
5.99.1.3 (https://enzyme.expasy.org/EC/5.99.1.3))

Category:Ligases (EC 6) (Ligase)

Category:EC 6.1 (form carbon-oxygen bonds)

6-carboxytetrahydropterin synthase

Category:EC 6.1.1
FARSB (EC 6.1.1.20 (https://enzyme.expasy.org/EC/6.1.1.20))
Category:EC 6.2 (form carbon-sulfur bonds)
EC 6.2.1.1 (https://enzyme.expasy.org/EC/6.2.1.1): Acetate--CoA ligase
EC 6.2.1.2 (https://enzyme.expasy.org/EC/6.2.1.2): Medium-chain acyl-CoA ligase
EC 6.2.1.3 (https://enzyme.expasy.org/EC/6.2.1.3): Long-chain-fatty-acid-CoA ligase
EC 6.2.1.4 (https://enzyme.expasy.org/EC/6.2.1.4): Succinate-CoA ligase (GDP-forming)
EC 6.2.1.5 (https://enzyme.expasy.org/EC/6.2.1.5): Succinate-CoA ligase (ADP-forming)
EC 6.2.1.6 (https://enzyme.expasy.org/EC/6.2.1.6): Glutarate-CoA ligase
EC 6.2.1.7 (https://enzyme.expasy.org/EC/6.2.1.7): Cholate-CoA ligase
EC 6.2.1.8 (https://enzyme.expasy.org/EC/6.2.1.8): Oxalate-CoA ligase
EC 6.2.1.9 (https://enzyme.expasy.org/EC/6.2.1.9): Malate-CoA ligase
EC 6.2.1.10 (https://enzyme.expasy.org/EC/6.2.1.10): Acid-CoA ligase (GDP-forming)
EC 6.2.1.11 (https://enzyme.expasy.org/EC/6.2.1.11): Biotin-CoA ligase
EC 6.2.1.12 (https://enzyme.expasy.org/EC/6.2.1.12): 4-coumarate-CoA ligase
EC 6.2.1.13 (https://enzyme.expasy.org/EC/6.2.1.13): Acetate-CoA ligase (ADP-forming)
EC 6.2.1.14 (https://enzyme.expasy.org/EC/6.2.1.14): 6-carboxyhexanoate-CoA ligase
EC 6.2.1.15 (https://enzyme.expasy.org/EC/6.2.1.15): Arachidonate-CoA ligase
EC 6.2.1.16 (https://enzyme.expasy.org/EC/6.2.1.16): Acetoacetate-CoA ligase
EC 6.2.1.17 (https://enzyme.expasy.org/EC/6.2.1.17): Propionate-CoA ligase
EC 6.2.1.18 (https://enzyme.expasy.org/EC/6.2.1.18): Citrate-CoA ligase
EC 6.2.1.19 (https://enzyme.expasy.org/EC/6.2.1.19): Long-chain-fatty-acid-luciferin-
component ligase
EC 6.2.1.20 (https://enzyme.expasy.org/EC/6.2.1.20): Long-chain-fatty-acid-(acyl-carrier-
protein) ligase
EC 6.2.1.21 (https://enzyme.expasy.org/EC/6.2.1.21): Transferred entry: 6.2.1.30
EC 6.2.1.22 (https://enzyme.expasy.org/EC/6.2.1.22): (citrate (pro-3S)-lyase) ligase
EC 6.2.1.23 (https://enzyme.expasy.org/EC/6.2.1.23): Dicarboxylate-CoA ligase
EC 6.2.1.24 (https://enzyme.expasy.org/EC/6.2.1.24): Phytanate-CoA ligase
EC 6.2.1.25 (https://enzyme.expasy.org/EC/6.2.1.25): Benzoate-CoA ligase
EC 6.2.1.26 (https://enzyme.expasy.org/EC/6.2.1.26): o-succinylbenzoate-CoA ligase
EC 6.2.1.27 (https://enzyme.expasy.org/EC/6.2.1.27): 4-hydroxybenzoate-CoA ligase
EC 6.2.1.28 (https://enzyme.expasy.org/EC/6.2.1.28): 3a,7a-dihydroxy-5b-cholestanate-CoA
ligase
EC 6.2.1.29 (https://enzyme.expasy.org/EC/6.2.1.29): Transferred entry: 6.2.1.7
EC 6.2.1.30 (https://enzyme.expasy.org/EC/6.2.1.30): Phenylacetate-CoA ligase
EC 6.2.1.31 (https://enzyme.expasy.org/EC/6.2.1.31): 2-furoate-CoA ligase
EC 6.2.1.32 (https://enzyme.expasy.org/EC/6.2.1.32): Anthranilate-CoA ligase
EC 6.2.1.33 (https://enzyme.expasy.org/EC/6.2.1.33): 4-chlorobenzoate-CoA ligase
EC 6.2.1.34 (https://enzyme.expasy.org/EC/6.2.1.34): Trans-feruloyl-CoA synthase
EC 6.2.1.35 (https://enzyme.expasy.org/EC/6.2.1.35): ACP-SH:acetate ligase
EC 6.2.1.36 (https://enzyme.expasy.org/EC/6.2.1.36): 3-hydroxypropionyl-CoA synthase
EC 6.2.1.37 (https://enzyme.expasy.org/EC/6.2.1.37): 3-hydroxybenzoate—CoA ligase
EC 6.2.1.38 (https://enzyme.expasy.org/EC/6.2.1.38): (2,2,3-trimethyl-5-oxocyclopent-3-
enyl)acetyl-CoA synthase
EC 6.2.1.39 (https://enzyme.expasy.org/EC/6.2.1.39): (butirosin acyl-carrier protein)—L-
glutamate ligase
EC 6.2.1.40 (https://enzyme.expasy.org/EC/6.2.1.40): 4-hydroxybutyrate-CoA ligase
EC 6.2.1.41 (https://enzyme.expasy.org/EC/6.2.1.41): 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-
octahydro-1H-inden-4-yl)propanoate-CoA ligase
EC 6.2.1.42 (https://enzyme.expasy.org/EC/6.2.1.42): 3-oxocholest-4-en-26-oate-CoA ligase
EC 6.2.1.43 (https://enzyme.expasy.org/EC/6.2.1.43): 2-hydroxy-7-methoxy-5-methyl-1-
naphthoate-CoA ligase
EC 6.2.1.44 (https://enzyme.expasy.org/EC/6.2.1.44): 3-(methylthio)propionyl-CoA ligase
EC 6.2.1.45 (https://enzyme.expasy.org/EC/6.2.1.45): E1 ubiquitin-activating enzyme
EC 6.2.1.46 (https://enzyme.expasy.org/EC/6.2.1.46): L-allo-isoleucine--holo-CmaA peptidyl-
carrier protein ligase
EC 6.2.1.47 (https://enzyme.expasy.org/EC/6.2.1.47): Medium-chain-fatty-acid-(acyl-carrier-
protein) ligase
EC 6.2.1.48 (https://enzyme.expasy.org/EC/6.2.1.48): Carnitine-CoA ligase
EC 6.2.1.49 (https://enzyme.expasy.org/EC/6.2.1.49): Long-chain fatty acid
adenylyltransferase FadD28
EC 6.2.1.50 (https://enzyme.expasy.org/EC/6.2.1.50): 4-hydroxybenzoate adenylyltransferase
FadD22
EC 6.2.1.51 (https://enzyme.expasy.org/EC/6.2.1.51): 4-hydroxyphenylalkanoate
adenylyltransferase FadD29
EC 6.2.1.52 (https://enzyme.expasy.org/EC/6.2.1.52): L-firefly luciferin-CoA ligase
EC 6.2.1.53 (https://enzyme.expasy.org/EC/6.2.1.53): L-proline-L-prolyl-carrier protein ligase
EC 6.2.1.54 (https://enzyme.expasy.org/EC/6.2.1.54): D-alanine-D-alanyl-carrier protein ligase
EC 6.2.1.55 (https://enzyme.expasy.org/EC/6.2.1.55): E1 SAMP-activating enzyme

Category:EC 6.3 (form carbon-nitrogen bonds)


Glutamine synthetase (EC 6.3.1.2 (https://enzyme.expasy.org/EC/6.3.1.2))
Argininosuccinate synthetase (EC 6.3.4.5 (https://enzyme.expasy.org/EC/6.3.4.5))
CTP synthase (EC 6.3.4.2 (https://enzyme.expasy.org/EC/6.3.4.2))

Category:EC 6.4 (form carbon-carbon bonds)


Pyruvate carboxylase (EC 6.4.1.1 (https://enzyme.expasy.org/EC/6.4.1.1))
Acetyl-CoA carboxylase (EC 6.4.1.2 (https://enzyme.expasy.org/EC/6.4.1.2))

Category:EC 6.5 (form phosphoric ester bonds)

DNA ligase (EC 6.5.1.1 (https://enzyme.expasy.org/EC/6.5.1.1))

Category:EC 6.6 (form nitrogen-metal bonds)

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