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Gentamicin Nursing Considerations

This document provides information about the generic drug gentamicin sulfate including its dosage, indications, adverse effects, nursing responsibilities, and client teaching points. Gentamicin sulfate is an aminoglycoside antibiotic used to treat serious infections caused by sensitive strains of bacteria. It works by inhibiting protein synthesis through binding to ribosomes. Common adverse effects include ototoxicity, nephrotoxicity, and neurotoxicity. Nurses are responsible for assessing the patient's infection and hearing before and during therapy. Client teaching includes monitoring for signs of adverse effects and following the prescribed dosage and duration of therapy.

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Miguel Sanico
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3K views2 pages

Gentamicin Nursing Considerations

This document provides information about the generic drug gentamicin sulfate including its dosage, indications, adverse effects, nursing responsibilities, and client teaching points. Gentamicin sulfate is an aminoglycoside antibiotic used to treat serious infections caused by sensitive strains of bacteria. It works by inhibiting protein synthesis through binding to ribosomes. Common adverse effects include ototoxicity, nephrotoxicity, and neurotoxicity. Nurses are responsible for assessing the patient's infection and hearing before and during therapy. Client teaching includes monitoring for signs of adverse effects and following the prescribed dosage and duration of therapy.

Uploaded by

Miguel Sanico
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd

GENERIC DOSE, INDICATION/ ADVERSE/SIDE NURSING RATIONALE CLIENT

NAME AND STRENGTH & MECHANISM OF EFFECTS RESPONSIBILITIES (10%) TEACHING


BRAND NAME FORMULATION DRUG ACTION DRUG INTERACTION (15%) (20%)
(15%) (15%)
(10%) (10%)

GENERIC: ORDERED: INDICATIONS: ADVERSE ASSESSMENT:


Gentamicin Serious infection REACTION: 1. Assess patient’s
sulfate caused by CNS: headache, infection and
TIMING: sensitive strains lethargy, numbness, hearing before
of Pseudomonas paresthesia, peripheral starting therapy and
aeruginosa, neuropathy, regularly thereafter.
BRAND: Escherichia coli, neurotoxicity, seizures, 2. Obtain specimen
DURATION: Proteus, twitching for culture and
Klebsiella, EENT: ototoxicity sensitivity tests
unknown Serratia, GU: nephrotoxicity before giving the
Eneterobacter, Hematologic: first dose.
CLASSIFICA Citrobacter, agranulocytosis, 3. weigh patient
TION: Staphylococcus. leucopenia, and review baseline
OTHER FORMS: thrombocytopenia renal function
Aminoglycoside; Injection: 40 M.O.A.: Other: hypersensitivity studies before
antibiotic mg/ml (adults), Chemical effect: reactions therapy and
10 mg/ml Inhibits protein regularly during
(pediatrics), 2 synthesis by DRUG therapy
mg/ml binding to INTERACTIONS: 4. therapy usually
(intrathecal) ribosomes. Drug-drug: Acyclovir, continues for 7 to
IV Infusion amphotericin B, 10 days. If no
(premixed): 40 Therapeutic cisplatin, response occurs in
mg, 60 mg, 80 effect: Kills methoxyflurane, other 3 to 5 days, therapy
mg, 90 mg, 100 susceptible aminoglycosides, maybe stopped
mg, 120 mg, 160 bacteria (many vancomycin: May
mg, 180 mg aerobic gram- increase ototoxicity and
available in saline negative nephrotoxicity. Use
solution organisms and together cautiously.
some aerobic Diuretics: May increase
gram-positive ototoxicity. Avoid use
organisms). Drug together.
may act against General Anesthetics:
some May increase effects of
aminoglycoside- non-depolarizing
resistant bacteria. muscle relaxant,
including prolonged
respiratory depression.
Use together only when
necessary.
Neurotoxic drugs: May
increase neurotoxicity.
Avoid use together.
Parenteral ampicillins:
May inactivate
gentamicin in vitro.
Don’t mix together.

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