Dosis Digoxin

(Sediaan: 0,5 mg/2ml)  0,5 mg/10ml

1mg
Dosis Dewasa = = 0,017 mg/kgBB
60kg

37
Dosis Mencit = 0,017 mg/kgBB x = 0,21 mg/kgBB
3

0,21 mg
Dosis Maks = x 30g = 0,0063 mg
1000 g

Larutan Stok (untuk 10 kelompok) =

Pengenceran 0,5mg/2ml  0,5 mg/10 ml  0,05 mg/ml

V1.C1 = V2.C2

V 2. C 2 0,0063 mgx 10 ml
V1 = = =1,26 ml  Dicukupkan 10 ml
C1 0 , 0 5 mg/ml

Larutan stok 0,0063 mg/ml

1. Digoksin 0,5 mg/2ml

1mg
Dosis Dewasa = = 0,017 mg/kgBB
60kg

37
Dosis Mencit = 0,017 mg/kgBB x = 0,21 mg/kgBB
3

0,21 mg
Dosis Maks = x 30g = 0,0063 mg
1000 g

Larutan Stok (untuk 10 kelompok) =

Pengenceran 0,5mg/2ml  0,5 mg/10 ml  0,05 mg/ml

V1.C1 = V2.C2

V 2. C 2 0,0063 mgx 10 ml
V1 = = =1,26 ml  Dicukupkan 10 ml
C1 0,05 mg/ml

Larutan stok 0,0063 mg/ml

2. Bisoprolol = 10 mg, berat etiket rata-rata 122 mg

10mg
Dosis Dewasa = = 0,16 mg/kgBB
60kgBB

Dosis Mencit = 0,16 mg/kgBB x 37

= 1, 973 mg/kgBB
3

Dosis Maks = 1,973 mg

x 30g = 0,05919 mg
1000 g

Larutan stok = 5mL

x 0,05919 mg = 0,29595 mg
1 mL

BYD = 0,2959 5mg

x 122 mg = 3,61059 mg
10 mg

Pengenceran =

50 mg 5 mL (1 mg/5 mL)

X 5 mL (3,61059mg/5mL)

X= 3,61059mg
x 5 mL = 0,36 mL
50 mg

Bisoprolol = 5 mg, berat etiket rata-rata 110 mg

5mg
Dosis Dewasa = = 0,083 mg/kgBB
 60kgBB

Dosis Mencit = 0,083 mg/kgBB x 37

= 1, 023 mg/kgBB
3

Dosis Maks = 1,973 mg

x 30g = 0,030 mg
1000 g

Larutan stok = 5mL

x 0,030 mg = 0,15 mg
1 mL

BYD = 0,15mg
x 110 mg = 3,3 mg
5 mg

Pengenceran =

50 mg 5 mL (1 mg/5 mL)

X 5 mL (3,30mg/5mL)

X= 3.30mg
x 5 mL = 0,33 mL
50 mg
Dosis Epinefrin
(Sediaan: 1 mg/1ml)  1mg/10 ml
1mg
Dosis Dewasa = = 0,017 mg/kgBB
60kg

37
Dosis Mencit = 0,017 mg/kgBB x = 0,21 mg/kgBB
3

0,21 mg
Dosis Maks = x 30g = 0,0063 mg
1000 g

Larutan Stok (untuk 10 kelompok) =

Pengenceran 1mg/ml  1mg/10 ml  0,1mg/ml

V1.C1 = V2.C2

V 2. C 2 0,0063 mg/mlx 10 ml
V1 = = =0,63 ml  Dicukupkan 10 ml
C1 0 ,1 mg/ ml

Larutan stok 0,0063 mg/ml

1. Clonidin (Catapres) = 150 mcg, Berat etiket rata-rata 170 mg
150mcg
Dosis Dewasa = = 2,5 mcg/kgBB
60kg

Dosis Mencit = 2,5 mcg/kgBB x 37

= 30,83 mcg/kgBB
3

Dosis Maks = 30,83 mcg

x 30g = 0,925 mcg
(untuk mencit 30g) 1000 g

Larutan Stok (untuk 10 kelompok) =

Pengenceran 150 mcg/ml  150 mcg/10 ml  15 mcg/ml

V1.C1 = V2.C2

V 2. C 2 0 , 925 mc gx 10 ml
V1 = = =0 , 62 ml  Dicukupkan 10 ml
C1 15 mc g /ml

Larutan stok 0,925 mcg/ml

Larutan stok = 5mL

x 0,925 mcg = 4,6445 mcg
1 mL

BYD = 4,6445 mcg

x 170 mg = 5,263 mg
150 mcg

Pengenceran =

50 mg 5 mL (1 mg/5 mL)

X 5 mL (0,5263 mg/5mL)
X= 5,263mg
x 5 mL = 0.5263 mL
50mg