INTRO

ist
Epidermis hypodermis
Dermis lympho lupus lichen drug
interface individual cell apop panniculitis deep indurated
granulomatous
spongiosum eczema 19edema erythema nodosum
vasculopathic
psoriasiform lupus
purpura
vesiculobullous
dbdo arthritis buttons pemphigoid
pain
pemphigus vulgaris
necrosisof small
dermal vessels dit

IgA deposition Non scarring alopecia

androgenetic
trichotillomania
telogen effluvium

crust dried fluid

scale 9keratin
scar fibrosis
keloid hypertrophic scar

erosion laceration epi

ulcer racer dermis
 AUTOIMMUNE
diffuse
systemic sclerosis thickening of skin Is
inflamm fibrosis vasculopathy
Ab anti centromere t anti sci o limited
CREST
systemic lungs heart kidney 61 calcinosi
Generalized
Raynaud
Localized scleroderma Morphed 23 body sites esophageal dysmotil
thickening of skin but no systemic sclerodactyly

features
o telangiestasia

i 1 I
Linea
Eh Parry
Morphed Coup
Romberg
limbs trunkhead de Sabre
children furrow atrophy of Yz face
Bush lines skin fat bone
replaced w
collagen

Acute cutaneous subacute chronic

lupus erythematosus

4111 polycyclic lesions discoid

SOAP MD BRAIN on extensor Csun exposed

malar rash
raynaud
photosens
ulcers

Dermatomyositis
prox muscle weakness
rash
violaceous
purple keratotic papule rash
on bony prominences
thickened cuticle
looped cap prominent bv
 30 60 y lo 270 y lo
emphus vulgaris pullous Pemphigoid more common
no itch oral first then skin of
trunk
Ab attack desmosomes burning itch
blister Ab attach hemidesmosomes
ntraepidermal
subepidermal blisters
tire Nikolosfy's sign
immunofluoresce Idiopathic or drug induced
pp El
X high dose steroids ACE
can be drug induced statin
furosemide
piperacillin
ACE ARB Tx steroids IVI G
cephalosporin