LUTEINISATION AND LUTEOLYSIS

• The tissues of the newly ruptured follicle do not just go away.

• Process of development of mature C.L by day 5th estrous cycle
• The newly formed CL begins to produce progesterone.
• It must be in the blood to maintain pregnancy.
• If pregnancy does not occur, the uterus produces PG F2α,
around day 17th of the oestrous cycle.
• PG F2α kills the C.L and causes it to regress in about 3-5 days.
• If its pregnancy, the embryo prevents the uterus from
releasing PG F2α, progesterone release continues from C.L

Dynamics of follicle
• FSH stimulates a group of follicles to grow or get recruit
(recruitment).
• FSH-Green line.
• These follicles continue to grow although some eventually die off
and regress, until only one remains and matures enough to
ovulate.
• Recruitment is the phase of follicular development in which a
cohort (group) of small antral follicles begins to grow and secrete
estradiol.
• Most of the recruited follicles undergo atresia. Follicles do nt
undergo atresia are selected. Selected follicles may become
dominant or undergo atresia. In pigs, dogs and cats, a cohort of
follicles becomes dominant.
• However, in cattle, mares, and women only a single follicle
becomes dominant.
• After recruitment LH is responsible to keep follicles growing.
• As previously mentioned, many of the follicles die off until only
one is left to mature. If progesterone is not gone from the blood
when that one follicle is ready to ovulate, then it also regresses
and lets a new group of follicles be recruited.

• After recruitment LH is responsible to keep follicles growing.

• Two or three groups of follicles are recruited before the CL is
gone and ovulation occurs.

FOLLICULAR WAVES
• After recruitment LH is responsible to keep follicles growing.
 HUBDAR ALI KOLACHI
LECTURER
DVM (GOLD MEDALIST), M. PHIL (SAU)